Clinical trials: Oxygen Reserve Index
Morbid Obesity, Surgery
Oxygen Reserve Index: Utility as Early Warning for Desaturation in Morbidly Obese Patients
The Oxygen Reserve Index (ORi) is a reference that could help clinicians with their assessments of normoxic and hyperoxic states by scaling the measured absorption information between 0.00 and 1.00.
- Trial name
- NCT03021551
- Testing
- Rainbow sensor
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Masimo Corporation
Healthy
Repeatability and Reproducibility of Oxygen Reserve Index (ORi)
This study is designed to evaluate the repeatability and reproducibility of ORi using an investigational Masimo rainbow sensor and FDA cleared rainbow sensors connected to the Masimo Radical-7 pulse oximeter and Masimo Root…
- Trial name
- NCT05636098
- Testing
- Masimo Rainbow Sensors
- Where
- United States
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Masimo Corporation
Atelectasis, Cesarean Section
The Effect of Oxygen Therapy on Atelectasis
In pregnancy, cephalal shift of the diaphragm caused by the enlarged uterus reduces the functional residual capacity and may increase the closure volume and predispose the pregnant woman to airway closure, leading to atelectasis.
- Conditions
- Atelectasis, Cesarean Section, Hypotension
- Trial name
- NCT05509764
- Testing
- lung ultrasound score
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Zonguldak Bulent Ecevit University
Desaturation, Apnea, Hypoxia
The Effectiveness of Oxygen Reserve Index in Early Detection of Desaturation in Geriatric Patients Scheduled for Oncological Surgery
This prospective observational study aims to evaluate the relationship between the Oxygen Reserve Index (ORI) and tolerable apnea time in geriatric patients undergoing elective oncologic surgery under general anesthesia.
- Conditions
- Desaturation, Apnea, Hypoxia, Oxygen Reserve Index
- Trial name
- NCT07326293
- Where
- Turkey (Türkiye)
- Volunteers
- 44 people
- Sponsor
- Ankara City Hospital Bilkent
Coronary Arterial Disease (CAD), Coronary Artery Bypass Graft (CABG)
Comparison of Oxygen Reserve Index and Spirometry in Predicting Respiratory Complications After Coronary Artery Bypass Surgery
Coronary artery disease (CAD) is one of the most common cardiac conditions, primarily caused by atherosclerosis. Studies have shown that environmental factors such as lifestyle, diet, genetics, and air pollution contribute to the…
- Conditions
- Coronary Arterial Disease (CAD), Coronary Artery Bypass Graft (CABG), Postoperative Pulmonary Complication
- Trial name
- NCT07063277
- Testing
- Preoperative Evaluation with ORI and Spirometry
- Where
- Turkey (Türkiye)
- Volunteers
- 142 people
- Sponsor
- Ankara Bilkent Sehir Hastanesi
Healthy
Oxygen Reserve Index (ORi) Validation of INVSENSOR00029
ORi is a unitless index that could help clinicians with their assessments or normoxic and hyperoxic states by scaling the measured absorption information between 0.00 and 1.00.
- Trial name
- NCT03678103
- Testing
- INVSENSOR00029
- Where
- United States
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Masimo Corporation
Oxygen Reserve Index Values
Evaluation of Oxygen Reserve Index According to Glasgow Coma Scale in Providing Oxygenation in Intracranial Surgery
Evaluation of oxygen reserve index according to Glasgow Coma Scale in providing oxygenation in intracranial surgery
- Trial name
- NCT05953493
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Trakya University
Healthy
Oxygen Reserve Index (ORi) Validation of INVSENSOR00025
ORi is a unitless index that could help clinicians with their assessments or normoxic and hyperoxic states by scaling the measured absorption information between 0.00 and 1.00.
- Trial name
- NCT03628898
- Testing
- INVSENSOR00025
- Where
- United States
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Masimo Corporation
Hyperoxemia, Oxygen Reserve Index
Oxygen Reserve Index and Prevention of Hyperoxemia
In patients under general anesthesia, the oxygen level (FiO2) used in inspiration is usually adjusted by monitoring the peripheral oxygen saturation level (SpO2).
- Conditions
- Hyperoxemia, Oxygen Reserve Index, Hyperoxia, Fraction of Inspired Oxygen
- Trial name
- NCT05505032
- Testing
- Oxygen, Masimo Root Radical 7
- Where
- Turkey (Türkiye)
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Baskent University Ankara Hospital
Apneic Oxygenation, Endolarengeal Surgery
Oxygen Reserve Index (ORi) in Identifying Desaturation
This randomized clinical trial investigates whether Oxygen Reserve Index (ORi) monitoring enables earlier detection of impending hypoxemia compared with conventional pulse oximetry during apneic intermittent ventilation in adult…
- Conditions
- Apneic Oxygenation, Endolarengeal Surgery, Oxygen Reserve Index
- Trial name
- NCT07415161
- Testing
- oxygen monitoring techniques
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Atelectasis, Lung Ultrasonography Score
Can Atelectasis Be Prevented With Oxygen Reserve Index (ORI) Monitoring?
This single-center randomized controlled trial aims to evaluate whether intraoperative monitoring using the Oxygen Reserve Index (ORI) reduces the incidence of postoperative atelectasis, as assessed by lung ultrasound (LUS), in…
- Conditions
- Atelectasis, Lung Ultrasonography Score, Hyperoxia
- Trial name
- NCT07050719
- Testing
- Peripheral Oxygen Saturation (SpO₂) Group, Peripheral Oxygen Saturation and Oxygen Reserve Index (SpO₂-ORI) Group
- Where
- Turkey (Türkiye)
- Volunteers
- 58 people
- Sponsor
- Antalya Training and Research Hospital
Healthy
Oxygen Reserve Index Validation for RD Lite Sensors
Oxygen Reserve Index (ORI) is a parameter that provides information on arterial partial pressure of oxygen (PaO2). In this study, the PaO2 is varied by controlling the concentration of oxygen the study volunteer breathes.
- Trial name
- NCT03128892
- Testing
- Oxygen Reserve Index - RD Lite Sensors
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Masimo Corporation
Out-Of-Hospital Cardiac Arrest, Oxygen Toxicity
ORI to Reduce Hyperoxia After Out Hospital Cardiac Arrest
The investigator's research proposal is a randomized controlled study evaluating two different monitoring strategies to titrate FiO2 in order to rapidly and safely achieve optimal SatO2 targets during early ROSC of non-traumatic…
- Trial name
- ORI-ONE (NCT03653325)
- Testing
- ORI measurement, oxygen saturation measurement
- Where
- 2 sites in Belgium
- Volunteers
- 100 people
- Sponsor
- Centre Hospitalier Universitaire Saint Pierre
Hypoxemia, Procedural Sedation
The Effectivity of End-tidal CO2 and Oxygen Reserve Index (ORI) Monitoring in Sedation
Endoscopic procedures are commonly performed using sedation. As drug-induced respiratory depression is a major cause of sedation-related morbidity, pulse oximetry has been established as standart practice .
- Conditions
- Hypoxemia, Procedural Sedation, Hypercapnia, Apnea
- Trial name
- NCT04793178
- Testing
- Oxygen Reserve Index, Masimo Corporation, USA.
- Volunteers
- 200 people
- Sponsor
- Yuksek Ihtisas Hospital
Hyperoxia, Hypoxia
The Association Between Sensory Block Level, Oxygen Therapy, and ORi in Varicose Vein Patients Undergoing Spinal Anesthesia (ORi: Oxygen Reserve Index)
The assessment of peripheral capillary oxygen saturation (SpO2) by pulse oximetry has become standard in perioperative care for the detection of hypoxaemia.
- Trial name
- ORi (NCT06566690)
- Testing
- Addition of ORi monitoring to SpO2 monitoring
- Where
- Turkey (Türkiye)
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Kocaeli University
Rhinoplasty, Oxidative Stress
Effect of ORI-guided Oxygen Titration on Oxidative Stress in Rhinoplasty Surgery
The aim of this study is to evaluate whether the use of Oxygen Reserve Index (ORİ) can prevent hyperoxia in patients undergoing rhinoplasty surgery and whether it can reduce oxidative stress caused by hyperoxia.
- Conditions
- Rhinoplasty, Oxidative Stress, Hyperoxia, Oxygen Reserve Index
- Trial name
- NCT07158073
- Testing
- FiO₂ titration, under the guidance of ORI, Conventional oxygen administration
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Dr. Lutfi Kirdar Kartal Training and Research Hospital
One Lung Ventilation in Thoracic Surgery
Oxygen Reserve Index Guided FiO₂ Titration in One-Lung Ventilation
One-lung ventilation (OLV) is routinely used during thoracic surgery to facilitate surgical exposure but is associated with an increased risk of intraoperative hypoxemia.
- Trial name
- NCT07359833
- Testing
- Oxygen Reserve Index (ORi)-guided oxygen titration
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Gazi University
Healthy
Oxygen Reserve Index (ORi) Expanded Data Set Validation of INVSENSOR00029
ORi is a unitless index that could help clinicians with their assessments of normoxic and hyperoxic states by scaling the measured absorption information between 0.00 and 1.00.
- Trial name
- NCT04079842
- Testing
- INVSENSOR00029
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Masimo Corporation
Healthy
Comparison of Preoxygenation Techniques in Healthy Volunteers With Monitoring of End-tidal Oxygen Fraction (FeO₂) and Oxygen Reserve Index (ORI)
The objective of this physiological study is to compare two preoxygenation techniques (non-invasive ventilation combined with high-flow nasal oxygen versus non-invasive ventilation alone) by monitoring end-tidal oxygen fraction…
- Trial name
- OXYGAME1 (NCT07334041)
- Testing
- Preoxygenation with VNI + OHD, Preoxygenation with VNI
- Where
- France
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Régional d'Orléans
General Anesthetic
Comparison of the Effects of High, Low and Minimal Flow Anesthesia Managements on ORI and Partial Oxygen Pressure
The aim of our study is to show that continuous oxygen reserve index monitoring is a non-invasive monitoring method that can be used as a supporting parameter to PaO2 in blood gas in hypoxia and hyperoxia monitoring when…
- Trial name
- NCT05329233
- Testing
- Masimo Radical-7 Pulse CO-Oximeter
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Samsun Education and Research Hospital