Clinical trials: Oxygen Reserve Index
Healthy
Oxygen Reserve Index (ORi) Validation of INVSENSOR00014
The Oxygen Reserve Index (ORi) is a reference that could help clinicians with their assessments of normoxic and hyperoxic states by scaling the measured absorption information between 0.00 and 1.00.
- Trial name
- NCT03500341
- Testing
- INVSENSOR00014
- Where
- United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Masimo Corporation
Atelectasis, Cesarean Section
The Effect of Oxygen Therapy on Atelectasis
In pregnancy, cephalal shift of the diaphragm caused by the enlarged uterus reduces the functional residual capacity and may increase the closure volume and predispose the pregnant woman to airway closure, leading to atelectasis.
- Conditions
- Atelectasis, Cesarean Section, Hypotension
- Trial name
- NCT05509764
- Testing
- lung ultrasound score
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Zonguldak Bulent Ecevit University
Apneic Oxygenation, Endolarengeal Surgery
Oxygen Reserve Index (ORi) in Identifying Desaturation
This randomized clinical trial investigates whether Oxygen Reserve Index (ORi) monitoring enables earlier detection of impending hypoxemia compared with conventional pulse oximetry during apneic intermittent ventilation in adult…
- Conditions
- Apneic Oxygenation, Endolarengeal Surgery, Oxygen Reserve Index
- Trial name
- NCT07415161
- Testing
- oxygen monitoring techniques
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Intensive Care Unit
Non-invasive Early Oxygen- Reserve-index (ORI) Determination to Prevent Hypoxaemia During Endotracheal Intubation
The purpose of this study is to determine whether ORI monitoring increases the lowest oxygen saturation level during the interval between the first laryngoscopy (defined as introduction of the laryngoscope into the mouth) and the…
- Trial name
- NESOI-2 (NCT05867875)
- Testing
- Unblinded ORI values, Blinded ORI values
- Where
- 21 sites in France
- Volunteers
- 950 people
- Sponsor
- Nantes University Hospital
Hyperoxia, Hyperoxemia
Hyperoxemia and Oxygen Reserve Index During Neurointerventional Anesthesia
The goal of this observational study is to learn how often high blood oxygen levels (hyperoxemia) occur in adults receiving general anesthesia for planned (elective) neurointerventional procedures, such as brain aneurysm coiling…
- Conditions
- Hyperoxia, Hyperoxemia, Cerebrovascular Disorders, Intracranial Aneurysms
- Trial name
- NCT07859982
- Testing
- Oxygen Reserve Index Monitoring (Observational)
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Fatih Sultan Mehmet Training and Research Hospital
Sarcopenia, Preoxygenation
Comparison of the Time to Reach End-Tidal Oxygen Value of 90 and Oxygen Reserve Index Decline Times During Preoxygenation in Sarcopenic and Non-Sarcopenic Patients
The purpose of this study is to compare the time required to reach an end-tidal oxygen (EtO2) value of 90% and the time until the Oxygen Reserve Index (ORI) drops below 0.55 during preoxygenation in sarcopenic and non-sarcopenic…
- Conditions
- Sarcopenia, Preoxygenation, Oxygen Reserve Index
- Trial name
- NCT06847672
- Testing
- preoxygenation
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Ankara City Hospital Bilkent
Healthy
Repeatability and Reproducibility of Oxygen Reserve Index (ORi)
This study is designed to evaluate the repeatability and reproducibility of ORi using an investigational Masimo rainbow sensor and FDA cleared rainbow sensors connected to the Masimo Radical-7 pulse oximeter and Masimo Root…
- Trial name
- NCT05636098
- Testing
- Masimo Rainbow Sensors
- Where
- United States
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Masimo Corporation
Oxygen Reserve Index
Oxygen Reserve Index in Different Fresh Gas Flow
Our primary objective is to determine whether oxygen reserve index ORI can be a reliable and sensitive indicator of hypoxia and hyperoxia in low-flow anesthesia settings.
- Trial name
- NCT06649279
- Testing
- Oxygen reserve index
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people
- Sponsor
- Sakarya University
Healthy
Oxygen Reserve Index (ORi) Validation of INVSENSOR00029
ORi is a unitless index that could help clinicians with their assessments or normoxic and hyperoxic states by scaling the measured absorption information between 0.00 and 1.00.
- Trial name
- NCT03678103
- Testing
- INVSENSOR00029
- Where
- United States
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Masimo Corporation
Brain Death
ORI and ETCO₂ Relationship With Arterial Blood Gas During Apnea Test
This observational study aims to evaluate the relationship between the Oxygen Reserve Index (ORI) and End-Tidal Carbon Dioxide (ETCO2) values with arterial blood gas parameters in patients undergoing the apnea test for the…
- Trial name
- NCT06983990
- Testing
- No intervention (observational monitoring only)
- Where
- Turkey (Türkiye)
- Volunteers
- 35 people
- Sponsor
- Bursa Yuksek Ihtisas Training and Research Hospital
Pre-operative Exercise
Evaluation of the Effects of Preoperative Breathing Exercises on Preoxygenation Period
The aim of this observational study is to compare the effects of preoperative breathing exercises during the preoxygenation period in patients undergoing abdominal surgery.
- Trial name
- NCT06401096
- Testing
- Preoperative respiratory exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 194 people, healthy volunteers welcome
- Sponsor
- Ankara City Hospital Bilkent
Morbid Obesity, Surgery
Oxygen Reserve Index: Utility as Early Warning for Desaturation in Morbidly Obese Patients
The Oxygen Reserve Index (ORi) is a reference that could help clinicians with their assessments of normoxic and hyperoxic states by scaling the measured absorption information between 0.00 and 1.00.
- Trial name
- NCT03021551
- Testing
- Rainbow sensor
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Masimo Corporation
Hyperoxemia, Intraoperative Oxygen Therapy
Oxygen Reserve Index-Guided Oxygen Titration During Surgery in the Beach Chair Position
This study aims to evaluate whether guidance by the Oxygen Reserve Index (ORi) improves inspiratory oxygen fraction (FiO₂) titration compared with conventional pulse oximetry (SpO₂)-guided oxygen administration in adult patients…
- Conditions
- Hyperoxemia, Intraoperative Oxygen Therapy, Beach Chair Position, Cerebral Oxygenation
- Trial name
- ORI-BCP (NCT07404267)
- Testing
- ORi-Guided FiO₂ Titration, SpO₂-Guided FiO₂ Titration
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Fatih Sultan Mehmet Training and Research Hospital
Obesity &Amp;Amp; Overweight, Elderly (People Aged 65 or More)
Evaluation of Oxygen Reserve Index (ORi) in Obese and Non-Obese Patients Over 65 Years Old
After obtaining ethical committee approval, this single-center, prospective, observational study included volunteer patients of both sexes, aged 65 years and older, with ASA II-III risk scores, who were scheduled for elective…
- Conditions
- Obesity &Amp;Amp; Overweight, Elderly (People Aged 65 or More), Oxygen Reserve Index
- Trial name
- NCT07679724
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Ankara City Hospital Bilkent
One Lung Ventilation in Thoracic Surgery
Oxygen Reserve Index Guided FiO₂ Titration in One-Lung Ventilation
One-lung ventilation (OLV) is routinely used during thoracic surgery to facilitate surgical exposure but is associated with an increased risk of intraoperative hypoxemia.
- Trial name
- NCT07359833
- Testing
- Oxygen Reserve Index (ORi)-guided oxygen titration
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Gazi University
Hyperoxemia, Oxygen Reserve Index
Oxygen Reserve Index and Prevention of Hyperoxemia
In patients under general anesthesia, the oxygen level (FiO2) used in inspiration is usually adjusted by monitoring the peripheral oxygen saturation level (SpO2).
- Conditions
- Hyperoxemia, Oxygen Reserve Index, Hyperoxia, Fraction of Inspired Oxygen
- Trial name
- NCT05505032
- Testing
- Oxygen, Masimo Root Radical 7
- Where
- Turkey (Türkiye)
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Baskent University Ankara Hospital
Healthy
Oxygen Reserve Index Validation for RD Lite Sensors
Oxygen Reserve Index (ORI) is a parameter that provides information on arterial partial pressure of oxygen (PaO2). In this study, the PaO2 is varied by controlling the concentration of oxygen the study volunteer breathes.
- Trial name
- NCT03128892
- Testing
- Oxygen Reserve Index - RD Lite Sensors
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Masimo Corporation
Hypoxia
Oxygen Reserve Index for Kids
In infants less than two years old the new Oxygen Reserve Index (ORI) will be measured during general anaesthesia. It will evaluated if and how ORI-monitoring gives earlier warning of hypoxaemia than conventional oxygen…
- Trial name
- ORIkids (NCT03845192)
- Testing
- ORI measurement by Radical 97
- Where
- Germany
- Volunteers
- 107 people
- Sponsor
- Johannes Gutenberg University Mainz
One-Lung Ventilation, Hypoxemia During Surgery
Oxygen Reserve Index in One-Lung Ventilation During Elective Thoracic Operations
The investigators' goal is to perform an observational cohort study investigating the use of oxygen reserve index (ORi) in patients undergoing elective thoracic surgery and one-lung ventilation (OLV).
- Conditions
- One-Lung Ventilation, Hypoxemia During Surgery, Oxygen Reserve Index, Perfusion Index
- Trial name
- NCT05050552
- Testing
- Masimo Radical-7 Pulse CO-Oximeter
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Trakya University
Hypoxemia
Pre-oxygenation in Sitting Position and Oxygen Reserve Index
This prospective, controlled and randomized study aims at comparing the effect of position on the oxygen reserve index alarm time which is considered as predictor of hypoxemia in prolonged apnea which might be faced during…
- Trial name
- NCT05964309
- Testing
- supine group, sitting group
- Where
- Saudi Arabia
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Imam Abdulrahman Bin Faisal University