Clinical trials: Oxidative Stress
Endothelial Function, Oxidative Stress
Black Forest Cocoa Flavanol Supplementation and Health Trial
This randomized, double-blind, controlled clinical trial will evaluate the effects of daily cocoa flavanol supplementation on vascular and inflammatory biomarkers in healthy adult men aged 30 to 75 years.
- Conditions
- Endothelial Function, Oxidative Stress, Inflamation, Vascular Health
- Trial name
- NCT07747714
- Testing
- Cocoa Flavanol Supplement, Low-Flavanol Control Powder
- Where
- 2 sites in United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- The Black Forest LLC
Eczema, Atopic Dermatitis
NPQ Plus Supplementation for Skin Health and Antioxidant Status
This study evaluated the effects of NPQ Plus supplementation on skin health, antioxidant status, fatigue, and self-perceived well-being in healthy adults with skin concerns.
- Conditions
- Eczema, Atopic Dermatitis, Skin Health, Fatigue Symptom
- Trial name
- NCT07703215
- Testing
- NPQ Plus
- Where
- Malaysia
- Volunteers
- 55 people
- Sponsor
- N REMEDIER (M) SDN BHD
Pigmentation, Oxidative Stress
A Study to Evaluate the Ability of Sunscreen Products to Modulate the Effects of Deep UVA +/- HEV Blue Light Induced Pigmentation and Biomarkers of Cutaneous Oxidative Stress
To assess the level of sub pigmentation following an acute exposure to a Deep Ultraviolet A and high energy Blue Light wavelengths (380-420 nm).
- Trial name
- NCT07695753
- Testing
- Sunscreen application #1, Sunscreen application #2
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Kenvue Brands LLC
Inflammation, Oxidative Stress
Reduction of Exposure, Inflammation, and Oxidative Stress Following at Least 2 Years of Switching to THS Use Compared to Cigarette Smoking
This is a cross-sectional 3-group study with subjects enrolled and matched by region (Asia, Europe), age, sex, and average daily product consumption over the last 2 years as self-reported.
- Conditions
- Inflammation, Oxidative Stress, Smoking, Smoking Abstinence
- Trial name
- NCT05385055
- Testing
- THS use, Cigarette smoking, Smoking abstinence
- Where
- 37 sites in Bulgaria, Czechia and 4 more
- Volunteers
- 974 people, healthy volunteers welcome
- Sponsor
- Philip Morris Products S.A.
Skin Condition, Anti-Oxidative Stress
Efficacy Evaluation Study of Vitamin C and Glutathione Liquid Sachet
The objective of this study is to evaluate the effect of liquid vitamin C and glutathione supplements on human skin condition improvement and anti-oxidation.
- Trial name
- NCT07379216
- Testing
- Vitamin C and Glutathione Liquid Sachet
- Where
- Taiwan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- TCI Co., Ltd.
Oxidative Stress
Bioavailability of PRUVIN® and Its Effects in Healthy Subjects (INDIGO)
To evaluate the effect of different doses of PRUVIN® (N-acetylcysteine [NAC] and glycine) on reduced glutathione levels in healthy elderly subjects
- Trial name
- NCT05041179
- Testing
- Pruvin R, Isomaltulose
- Where
- Germany
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Société des Produits Nestlé (SPN)
Psychological Well-Being, Oxidative Stress
A Study to Assess the Efficacy of CaroRite™ on Psychological Well-being, Oxidative Stress and Quality of Life in Healthy Individuals
The present study is a randomized, placebo-controlled, double-blind clinical study in which 94 individuals will be screened, and considering a screening failure rate of 20%, approximately 76 participants will be randomized in a…
- Conditions
- Psychological Well-Being, Oxidative Stress, Quality of Life
- Trial name
- NCT05931315
- Testing
- CaroRite™
- Where
- 4 sites in India
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Vedic Lifesciences Pvt. Ltd.
Oxidative Stress
Sperm Oxidative Stress and Pregnancy Success During IUI and IVF
Oxidative stress (OS) is characterized by an imbalance between the production of reactive oxygen species (ROS) and the ability of the body to eliminate them.
- Trial name
- NCT03539874
- Where
- Canada
- Volunteers
- 250 people
- Sponsor
- Fertilys
Skin Fold, Skin Laxity
A Safety and Effectiveness Study of CELLBOOSTER® Lift (Stabilized Booster Complex Using CHAC Technology)
The current post-market clinical investigation has been designed to evaluate the efficacy and safety of CELLBOOSTER® Lift, a HA-based product marketed by SUISSELLE SA.
- Conditions
- Skin Fold, Skin Laxity, Skin Texture Disorder, Skin Depression
- Trial name
- NCT06000839
- Testing
- (D0) Intradermal injection - micropapula technique, (D14) Intradermal injection - micropapula technique, (D28) Intradermal injection - micropapula technique
- Where
- France
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Suisselle
Oxidative Stress
Clinical Trial to Investigate the Efficacy and Safety of LN-OS-22 on Oxidative Stress and Systemic Inflammation in Overweight and Obese Population.
The present clinical investigation has been proposed to further substantiate the evidence of the antioxidant and anti-inflammatory activity of the extract in the healthy adult population with BMI ranging from ≥25.0 kg/m2 and ≤…
- Trial name
- NCT05404217
- Testing
- LN-OS-22, Maltodextrin
- Where
- 3 sites in India
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Vedic Lifesciences Pvt. Ltd.
Oxidative Stress, Inflammation
Antioxidant Effect of Ozonated Vegetable Oil and Vitamins in Moderately Active Subjects
The purpose of this pilot study is to evaluate the antioxidant effect of a nutraceutical formulation based on vegetable oil and vitamin complex (vitamin K2 and vitamin B9) in subjects with the same level of physical activity (LAF…
- Trial name
- ANTIOX001 (NCT05592509)
- Testing
- Ozonized vegetable oil with vitamines
- Where
- Italy
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- S&R Farmaceutici S.p.A.
Oxidative Stress
EValuation of the Antioxidant and Anti-inflammatory Capacity of Nutraceutical IMMU·SYSTEM Food Supplement (EVAANIS)
The aim of the study is to verify the effectiveness of Nutraceutical IMMU·SYSTEM Dietary supplement in reducing the levels of oxidative stress and inflammation in a sample of healthy adult subjects with high baseline levels of…
- Trial name
- EVAANIS (NCT04912947)
- Testing
- Immusystem
- Where
- Italy
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Complife Italia Srl
Skin Condition, Anti Oxidative Stress
Investigation of the Efficacies of Multi Berries Juice on Anti Oxidant Effect and Improvement of Skin Conditions
To assess multi berries juice on anti-oxidant effect and skin condition improvement
- Trial name
- NCT04878523
- Testing
- multi berries juice
- Where
- Taiwan
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- TCI Co., Ltd.
Oxidative Stress, Healthy Aging
Efficacy of Solarplast for Health and Oxidative Stress
Solarplast is a unique mixture of antioxidant enzymes and single antioxidant molecules that are capable of attack oxidants that cause damage to the cells in the human body and cause premature aging.
- Conditions
- Oxidative Stress, Healthy Aging, Skin Health
- Trial name
- NCT04144777
- Testing
- Solarplast
- Where
- United States
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Deerland Enzymes
Muscle Soreness, Muscle Damage
The Chronic Effects of Carnitine on Recovery
This study investigated the effects of CarnipureTM, a high-quality L-carnitine ingredient, on long term (5 weeks) recovery, muscle damage, and SOD status in a population of males and females while training two days per week.
- Conditions
- Muscle Soreness, Muscle Damage, Resistance Training, Oxidative Stress
- Trial name
- NCT04420377
- Testing
- Carnipure, Resistance Training
- Where
- United States
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Applied Science & Performance Institute
Oxidative Stress, Muscle Strength
The Short Term Effects of Oceanix Supplementation on Recovery
The purpose of this study will be to examine the effects of Oceanix supplementation on isometric mid-thigh pull force kinetics and salivary immunoglobulin A (indice of immune function) following a one-week intense resistance…
- Conditions
- Oxidative Stress, Muscle Strength, Resistance Training, Muscle Damage
- Trial name
- NCT04315077
- Testing
- Oceanix®, Resistance Training
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Applied Science & Performance Institute
Oxidative Stress, Muscle Strength
The Effects of Antioxidant Supplementation on Multiple Endurance Race Performance, Physiology, and Recovery.
Thirty active male and female athletes will be recruited for the study. Subjects will be examined at baseline for VO2max performance.
- Conditions
- Oxidative Stress, Muscle Strength, Resistance Training, Body Composition
- Trial name
- NCT04314596
- Testing
- Cross Training Course, Oceanix
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Applied Science & Performance Institute
Oxidative Stress, Muscle Strength
The Long-term Effects of Oceanix™ on Resistance Training Adaptations
This study will examine the effects of Oceanix™, an antioxidant supplement, on muscle performance, immune and endocrine function, recovery and safety in participants undergoing resistance training.
- Conditions
- Oxidative Stress, Muscle Strength, Resistance Training, Body Composition
- Trial name
- NCT04136821
- Testing
- Oceanix, Resistance Training
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Applied Science & Performance Institute
Oxidative Stress, Quality of Life
Effect of an Iridoid Enriched Beverage on Skin Autofluorescence
The objectives of this clinical trial are to evaluate the effectiveness of an iridoid enriched beverage containing noni and cornelian juices and olive leaf extract on advanced glycation end product levels.
- Conditions
- Oxidative Stress, Quality of Life, Metabolic Syndrome
- Trial name
- NCT01597076
- Testing
- iridoid enriched mixed fruit beverage
- Where
- Indonesia
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Tahitian Noni International, Inc.
Oxidative Stress
Safety and Tolerability of Antioxidant (AT-001)for Reducing Brain Oxidative Stress
The purpose of this study is to determine the safety, bioavailability, and effectiveness of an organic yeast-selenium compound in reducing brain oxidative stress.
- Trial name
- NCT01731093
- Testing
- AT-001
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Alltech Life Sciences Inc.