Clinical trials: Overweight (BMI > 25)
Obesity &Amp;Amp;Amp; Overweight, Environmental Exposure
Weight Loss and Endocrine Disrupting Chemicals (EDCs): Lifestyle Interventions to Lose Weight and Reduce EDC Exposure in Individuals With Overweight/Obesity
The goal of this study is to examine the relationship in individuals with overweight/obesity and endocrine disrupting chemical (EDC) exposure through a two-armed, randomized clinical trial.
- Conditions
- Obesity &Amp;Amp;Amp; Overweight, Environmental Exposure, Overweight (BMI > 25)
- Trial name
- LiveWell (NCT07560579)
- Testing
- Educational curriculum, Weight loss Application, Urinary EDC metabolite testing
- Where
- United States
- Volunteers
- 226 people
- Sponsor
- Million Marker Wellness, Inc.
Overweight (BMI > 25), Obesity & Overweight
WB-EMS Combined With Nutritional Guidance for a High-Protein Diet on Body Composition, Muscle Function, Psychological and Functional Outcomes in Older Adults With Excess Adiposity
This is a 16-week randomized controlled trial (RCT) with outcome assessor blinding. The objective is to investigate the effects of resistance training (RT) combined with whole-body neuromuscular electrical stimulation (WB-NMES)…
- Conditions
- Overweight (BMI > 25), Obesity & Overweight, Aging
- Trial name
- WB-EMS (NCT07859072)
- Testing
- Whole-Body Neuromuscular Electrical Stimulation (WB-NMES), Conventional Resistance Training, High-Protein Nutritional Guidance
- Where
- Brazil
- Volunteers
- 36 people
- Sponsor
- Universidade Cesumar (UNICESUMAR)
Impaired Glucose Regulation, Impaired Glucose Tolerance (Prediabetes)
Probiotic Impact on Cognitive Performance, and Metabolic Outcomes in Overweight Young Adults With Impaired Glucose Regulation
This 12-week, double-blind, placebo-controlled trial will examine whether daily supplementation with the Lab4P probiotic can improve cognitive performance and metabolic health in overweight adults aged 18 to 40 with impaired…
- Conditions
- Impaired Glucose Regulation, Impaired Glucose Tolerance (Prediabetes), Prediabetes (Insulin Resistance, Impaired Glucose Tolerance), Overweight (BMI > 25)
- Trial name
- ProCog (NCT07073781)
- Testing
- Lab4p Probiotic Consortium
- Where
- United Kingdom
- Volunteers
- 70 people
- Sponsor
- Leeds Beckett University
Overweight (BMI > 25), Obese, Otherwise Healthy Volunteers
L. Acidophilus (Strain TW01) on Gut Health, Body Composition, and Inflammation
This is a pilot research study to investigate the effects of a probiotic supplement (L. acidophilus, strain TW01) on substances found in the stool and bloodstream, gut bacteria composition, body composition, as well as any…
- Trial name
- NCT06912100
- Testing
- Probiotic
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Connecticut
Overweight (BMI > 25), Obesity
SMART Pilot Trial of Glycemic Screening Outreach
Approximately 130 million Americans have prediabetes or type 2 diabetes (T2D) but remain unscreened and/or unaware of their diagnosis.
- Trial name
- NCT06915194
- Testing
- Text message, Patient portal message, Mailed letter
- Where
- United States
- Volunteers
- 102 people
- Sponsor
- University of California, Los Angeles
MASLD - Metabolic Dysfunction-Associated Steatotic Liver Disease, Fatty Liver Disease, Nonalcoholic
Investigation of the Efficacy of a Probiotic Mixture in Moderate Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD): A Mechanistic Trial
The goal of this clinical trial is to evaluate whether a specific probiotic mixture can improve liver health in adults with moderate metabolic dysfunction-associated steatotic liver disease (MASLD).
- Conditions
- MASLD - Metabolic Dysfunction-Associated Steatotic Liver Disease, Fatty Liver Disease, Nonalcoholic, Overweight (BMI > 25)
- Trial name
- NCT07193927
- Testing
- Lactiplantibacillus plantarum Probiotic Mixture
- Where
- Spain
- Volunteers
- 60 people
- Sponsor
- AB Biotics, SA
Metabolic Dysfunction Associated Steatotic Liver Disease, Overweight (BMI > 25)
Feasibility of the Paso Program for Patients With Metabolic Dysfunction Associated Steatotic Liver Disease
The purpose of this study is to learn whether the Paso weight loss program is feasible for Mexican and Central American patients with fatty liver disease.
- Conditions
- Metabolic Dysfunction Associated Steatotic Liver Disease, Overweight (BMI > 25), Metabolic Syndrome
- Trial name
- NCT06854185
- Testing
- Paso Program
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Baylor College of Medicine
Overweight (BMI > 25), Obese Patients
Intervention Effects on Health Promoting Behaviors and Factors Influencing Long-Term Behavior Change
This study aims to compare the 8-week virtual Healthy YOU Program with a standard care intervention that sends weekly nutrition and healthy living tips via email.
- Trial name
- HYP (NCT06892587)
- Testing
- An 8-week virtual group intervention designed to promote sustainable health behavior changes in participants, Standard of care Nutritional Information
- Where
- United States
- Volunteers
- 68 people
- Sponsor
- Colorado State University
Overweight (BMI > 25), Obese But Otherwise Healthy Participants
Pistachio Snacking and Metabolic Flexibility
The purpose of this study is to evaluate the effects of pistachio snacking on metabolic flexibility (at rest, during exercise, and in post-exercise recovery) in healthy overweight and obese adults.
- Conditions
- Overweight (BMI > 25), Obese But Otherwise Healthy Participants, Overweight or Obese, Obese Patients (BMI ≥ 30 kg/m²)
- Trial name
- NCT07340125
- Testing
- Pistachio
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of South Carolina
Overweight (BMI > 25), Obesity and Overweight
The Effect of a ChatGPT-Supported Online Group-Guided Self-Help Program on Uncontrolled and Emotional Eating Behaviors and Body Image in Overweight and Obese Woman Nurses
Nurses with overweight and female gender characteristics often experience disruptions in their eating behaviors due to stressful working conditions.
- Conditions
- Overweight (BMI > 25), Obesity and Overweight, Emotional Eating, Binge Eating
- Trial name
- NCT06653673
- Testing
- ChatGPT supported Online Guided Self-Help Program (GSHP)
- Where
- Turkey (Türkiye)
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Dokuz Eylul University
Overweight (BMI > 25), Obesity &Amp; Overweight
Effects of Three Dietary Strategies on Body Composition and Metabolic Health in Adults With Overweight or Obesity
This study aims to compare the effects of three dietary interventions-a traditional Mediterranean diet, a Mediterranean low-carbohydrate diet, and a high-protein diet-on body composition, metabolic health markers, and metabolic…
- Conditions
- Overweight (BMI > 25), Obesity &Amp; Overweight, Metabolic Syndrome (MetS), Cardiometabolic Risk Factors
- Trial name
- NCT07314177
- Testing
- Mediterranean Diet, Mediterranean Low-Carbohydrate Diet, High-Protein Diet
- Where
- Spain
- Volunteers
- 45 people
- Sponsor
- Consorcio Centro de Investigación Biomédica en Red (CIBER)
Overweight (BMI > 25), Obesity
Redox Status and Exercise Training-induced Adaptations
Excess fat accumulation is a key feature of overweight and obesity that is mainly driven by nutrient overload and insufficient physical activity.
- Trial name
- NCT07196852
- Testing
- N Acetyl L Cysteine
- Where
- Greece
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Thessaly
Fat Mass, Risk Factors Cardiovascular Disease
Follow up Study of Varapodio Trial: Effect of Longevity and Fasting Mimicking Diet on Risk Factors Age Correlated and Biomarkers of Aging
A large ongoing randomized, open-label trial aimed at evaluating the effects of two different dietary interventions, FMD and LD, on body composition and cardiovascular (CV) biomarkers in a real word population (NCT05698654) is…
- Conditions
- Fat Mass, Risk Factors Cardiovascular Disease, Epigenetic Aging, Metabolism Changes
- Trial name
- NCT07255300
- Testing
- fasting mimicking diet
- Where
- Italy
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- Fondazione Valter Longo
Diabetes (DM), Pre Diabetes
FastForward: A Prospective Analysis of Long-term Fasting and Subsequent Food Reintroduction in Humans
This study explores what happens in the body and wellbeing during and after a period of long-term fasting. At the Buchinger Wilhelmi Clinic, participants follow a medically supervised fasting program lasting five or more days…
- Conditions
- Diabetes (DM), Pre Diabetes, Overweight (BMI > 25)
- Trial name
- FastForward (NCT07155993)
- Where
- Germany
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Buchinger Wilhelmi Development & Holding GmbH
Obese Patients, Overweight (BMI > 25)
Effects of Low-intensity Blood Flow Restriction Exercise on Aerobic Capacity, Muscle Strength, Muscle Size, Biochemical-hormonal Parameters and Antioxidant Parameters in Overweight and Obese Individuals.
Participants will be selected from sedentary men aged 18-30 and over with a body mass index of 25. First, an informed consent form will be signed by the individuals.
- Trial name
- YT BFR (NCT06912919)
- Testing
- BFR-Aerobic Training, Aerobic Training Without BFR
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Cardiovascular Risk Factors, Insulin Resistance
Ice Cream Enriched With Cimarrón Bean Extrudate and Cardiovascular Risk in Adults
The goal of this clinical trial is to evaluate the chronic effects of consuming a functional ice cream enriched with Cimarrón bean (Phaseolus vulgaris local variety Cimarrón) extrudate in adults with at least one cardiovascular…
- Conditions
- Cardiovascular Risk Factors, Insulin Resistance, Overweight (BMI > 25)
- Trial name
- ICE-CBE-CARD (NCT07076563)
- Testing
- Functional Ice Cream with Cimarrón Bean Extrudate
- Where
- Chile
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Talca
Cardiovascular Disease Risk Factor, Insulin Resistance
Acute Postprandial Effects of Functional Ice Cream With Cimarrón Bean Extrudate in Adults
The goal of this non-randomized clinical trial is to evaluate the acute postprandial metabolic effects of a functional ice cream enriched with Cimarrón bean (Phaseolus vulgaris L.
- Conditions
- Cardiovascular Disease Risk Factor, Insulin Resistance, Overweight (BMI > 25), Hyperglycaemia
- Trial name
- ICE-CBE-GLULIP (NCT07053267)
- Testing
- Funrional Ice Cream
- Where
- Chile
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Talca
Overweight (BMI > 25)
Prevent and Reverse Obesity in Children, Adolescents and Young Adults
Obesity and overweight are non-communicable diseases with an increasing incidence in children, adolescents, and adults. International efforts to reverse the current epidemiological trend of rising overweight, obesity, and related…
- Trial name
- PasGras (NCT07035704)
- Testing
- MeD enriched with mushrooms, MeD enriched the Lebanese herbal mixture Za'atar, MeD Diet + semaglutinine or compatible treatment+ Za'atar or Mushroom (to be defined)
- Where
- Italy
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- piero portincasa
Obesity, Overweight (BMI > 25)
Mapping Obesity-related Subtypes And Interconnected Clusters
In the Netherlands, about half of all adults are currently living with overweight. This number is expected to rise to as much as 64% by the year 2050, especially among younger adults aged 18 to 44.
- Trial name
- MOSAIC (NCT06960434)
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Zuyd University of Applied Sciences
Obesity, Overweight (BMI > 25)
Impact of Protein Supplementation and Resistance Training on Body Composition, Functional Parameters, Metabolic Adaptation, and Nitrogen Balance in Adults Aged 45 Years and Older With Overweight or Obesity Receiving Incretin-based Medications
This study aim to evaluate the effects of protein supplements and resistance training on body composition, functional parameters, metabolic adaptation, and nitrogen balance in adults (aged ≥45 years) with overweight/obesity…
- Conditions
- Obesity, Overweight (BMI > 25), Weight Loss
- Trial name
- PRIME (NCT06950684)
- Testing
- Whey Protein Supplement, Resistance Training Program
- Volunteers
- 180 people
- Sponsor
- Assuta Medical Center