Clinical trials: Overweight
Obesity
Metformin vs Conjugated Linoleic Acid and an Intervention Program With Healthy Habits in Obese Children
The purpose of this clinical trial is to examine the effects of conjugated linoleic acid (CLA) vs metformin along with an intervention program with healthy habits on body composition, weight, M value in CLAMP and clinical…
- Trial name
- NCT02063802
- Testing
- metformin, Conjugated Linoleic Acid, Healthy habits program
- Where
- Mexico
- Volunteers
- 120 people
- Sponsor
- Laboratorios Silanes S.A. de C.V.
Chronic Kidney Disease, Type 2 Diabetes
A Research Study to See if Kidney Damage in People With Chronic Kidney Disease and Type 2 Diabetes Living With Overweight or Obesity Can be Reduced by CagriSema Compared to Semaglutide, Cagrilintide and Placebo
This study will look if CagriSema can lower kidney damage in people with chronic kidney disease (CKD), type 2 diabetes (T2D) and overweight or obesity. CagriSema is a new investigational medicine.
- Conditions
- Chronic Kidney Disease, Type 2 Diabetes, Obesity
- Trial name
- NCT06131372
- Testing
- Cagrilintide, Semaglutide
- Where
- 129 sites in United States, Argentina and 11 more
- Volunteers
- 626 people
- Sponsor
- Novo Nordisk A/S
Weight Loss
Oral VK2735 for Weight Management in Adults With Type 2 Diabetes Mellitus Phase 3 (SUNRISE 2)
This study is one of two planned Phase 3 studies to support the weight management indication for VK2735 Oral in obese (BMI ≥ 30 kg/m2) or overweight (BMI ≥ 27 kg/m2) adults with Type 2 Diabetes Mellitus.
- Trial name
- NCT07868939
- Testing
- VK2735 Oral
- Volunteers
- 560 people
- Sponsor
- Viking Therapeutics, Inc.
Overweight and Obesity
A Study to Investigate the Safety and Tolerability of TE-8105 in Overweight/Obese Participants Without Diabetes
This is a Phase 1/2a, first-in-human, prospective, open-label study to evaluate the safety, tolerability, PK, PD, and effect on body weight of TE-8105 in overweight/obese participants without diabetes.
- Trial name
- NCT06471530
- Testing
- TE-8105 SAD Cohort 1, TE-8105 SAD Cohort 3, TE-8105 SAD Cohort 5 (Adaptive cohort)
- Where
- Australia
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Immunwork, Inc.
Overweight
Delivering Geospatial Intelligence to Health Care Providers
Physician counseling for physical activity, dental services, and academic support services such as tutoring could be improved through physician knowledge of local community resources and physician counseling directing patients to…
- Trial name
- CHICA GIS (NCT01567228)
- Testing
- CHICA GIS (enhanced electronic medical record)
- Where
- United States
- Volunteers
- 1,076 people
- Sponsor
- Indiana University
Weight Loss, Obesity
Weight Loss Using a Feedback Device in Obese People With the Metabolic Syndrome
The purpose of this study is to determine if a weight loss app (VA MOVE!® Coach App) along with regularly scheduled telephone counseling, will motivate obese people with metabolic syndrome to lose weight and improve the symptoms…
- Conditions
- Weight Loss, Obesity, Pre-Diabetes, Metabolic Syndrome
- Trial name
- NCT03491930
- Testing
- VA MOVE! Coach app, Telephone Coaching, Standard of Care for weight loss.
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Rockefeller University
Obesity, Overweight
Avoid and Resist Strategies for Weight Management
The proposed randomized controlled trial tests two self-regulatory approaches to improve intentional weight loss and diet quality in individuals with overweight or obesity: (1) an environmental control strategy (AVOID) and (2) an…
- Trial name
- NCT05143931
- Testing
- Home food environment and grocery delivery (AVOID), Inhibitory control training (RESIST), WW
- Where
- United States
- Volunteers
- 503 people, healthy volunteers welcome
- Sponsor
- Cedars-Sinai Medical Center
Body Weight Changes, Overweight and Obesity
A Self-directed Mobile Intervention to Promote Weight Control Among Employees of a Lebanese University
WaznApp study is a 12-week randomized controlled trial aimed to evaluate the feasibility and preliminary efficacy of a self-directed behavioral weight-loss intervention targeting employees of an academic institution, using two…
- Conditions
- Body Weight Changes, Overweight and Obesity, Sedentary Lifestyle, Health Behavior
- Trial name
- WaznApp (NCT03321331)
- Testing
- Lark (JITAI), MyFitnessPal (no JITAI)
- Where
- Lebanon
- Volunteers
- 123 people, healthy volunteers welcome
- Sponsor
- American University of Beirut Medical Center
Obesity, Hypertension
Lifestyle On-line Intervention in Patients With Obesity and Hypertension
This study aims to describe a totally self-applied online program to promote healthy lifestyles (nutritional education and exercise practice) for obese participants with hypertension.
- Trial name
- NCT03396302
- Testing
- Educational intervention
- Where
- Spain
- Volunteers
- 105 people
- Sponsor
- Cardenal Herrera University
Obesity
Diet Tracking Prescriptions for Weight Loss
Lifestyle interventions are effective at producing modest weight loss. One of the strongest predictors of weight loss is food tracking, which involves logging all food and beverage consumed each day in an effort to stay within a…
- Trial name
- NCT06311175
- Testing
- Dietary Tracking Prescription
- Where
- United States
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- University of Connecticut
Obesity and Obesity-related Medical Conditions, Appetite
Effects of Meal Characteristics on Appetite
The overall aim of the study is to determine effects of different meal characteristics on energy intake, eating rate and appetite.
- Trial name
- NCT07178405
- Testing
- Meal low in energy density, low in ultra-processed food, Meal low in energy density, high in ultra-processed food, Meal high in energy density, low in ultra-processed food
- Where
- Sweden
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- Göteborg University
Obesity
Prevention & Promotion in the Treatment of Obesity
Making healthy food choices requires sacrificing immediate pleasures of consuming high calorie foods in order to achieve long-term health goals.
- Trial name
- PROSPER (NCT02990494)
- Testing
- STANDARD, PREVENT, PROMOTE
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- The Miriam Hospital
Heart Failure, Diabetes Mellitus
Effects of a High Protein Diet on Clinical Outcomes in Heart Failure
This research project was designed to study the role of dietary modifications in heart failure (HF) patients that suffer from type 2 diabetes mellitus and obesity.
- Trial name
- NCT01423266
- Testing
- 12-week supervised weight loss intervention
- Where
- United States
- Volunteers
- 78 people
- Sponsor
- University of California, Irvine
Fetal Growth Restriction
A Randomized Air Filter Intervention Study of Air Pollution and Fetal Growth in a Highly Polluted Community
The purpose of this study is to use an air filter intervention to evaluate the relationship between particulate matter air pollution exposure during pregnancy and fetal growth.
- Trial name
- NCT01741051
- Testing
- HEPA Filter
- Where
- Mongolia
- Volunteers
- 540 people, healthy volunteers welcome
- Sponsor
- Simon Fraser University
Obesity
Effects of a Multimodal Preference-based Parental Intervention on Preschoolers' Physical Activity Behaviour - a Cluster-randomized Trial
This study investigates whether a preschool-based physical activity intervention involving parents as active agents of behavioral change affects objectively measured physical activity in preschool children.
- Trial name
- NCT01070251
- Testing
- Participatory parent-focused intervention, State-sponsored PA program
- Where
- 2 sites in Germany
- Volunteers
- 826 people
- Sponsor
- Heidelberg University
Pediatric Obesity
Nudge-Based Exercise Intervention for Adolescents With Obesity
This study will evaluate whether a nudge-based exercise program can improve body mass index (BMI) and physical activity in adolescents with obesity. About 140 adolescents aged 10-19 years will participate.
- Trial name
- NCT07824453
- Testing
- Standard Exercise Intervention, Nudge-Based Exercise Intervention
- Where
- China
- Volunteers
- 140 people
- Sponsor
- Nanjing Children's Hospital
Monogenic Obesity
A Study Evaluating Mibavademab Treatment of Obesity Due to Leptin (LEP) Gene Mutations in Children, Adolescents and Adults
This study is researching an experimental drug called mibavademab. The study is focused on patients with a condition called monogenic obesity.
- Trial name
- NCT07220772
- Testing
- Mibavademab
- Where
- 3 sites in Germany, Turkey (Türkiye)
- Volunteers
- 4 people
- Sponsor
- Regeneron Pharmaceuticals
Cancer, Obesity
Community Activation for Prevention (CAPs): A Study of Community Gardening
The investigators previous studies show that community gardening is associated with reduction of key health behaviors for cancer prevention in diverse populations.
- Conditions
- Cancer, Obesity, Lifestyle, Sedentary, Physical Activity
- Trial name
- CAPs (NCT03089177)
- Testing
- Community Garden Intervention
- Where
- United States
- Volunteers
- 296 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Boulder
Obesity
Pharmacokinetic Properties of Lorcaserin in Obese or Overweight Elderly Subjects
The purpose of this study is to evaluate the PK properties of lorcaserin in obese or overweight elderly subjects.
- Trial name
- NCT00828581
- Testing
- lorcaserin
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Eisai Inc.
Obesity, Metabolic Syndrome
Effect of Resvida, a Comparison With Calorie Restriction Regimen
The purpose of this study is to compare the effects of the antioxidant "resveratrol" to a diet intervention (Calorie Restriction) to determine how each of them affects the following: gene expression profile, cholesterol (lipids)…
- Conditions
- Obesity, Metabolic Syndrome, Diabetes, Aging
- Trial name
- Resvida (NCT00823381)
- Testing
- resveratrol, Calorie Restriction
- Where
- United States
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine