Clinical trials: Ovarian Reserve
Fertilization Failure
Calcium Ionophore Solution Can Increase Fertilization Rate in Patients During Intracytoplasmic Sperm Injection(ICSI) Who Have Poor Ovarian Reserve?
The aim of this study is to evaluate calcium ionophore solution on fertilization rate of patients during intracytoplasmic sperm injection who have poor ovarian reserve
- Trial name
- NCT02045914
- Testing
- calcium ionophore solution
- Where
- Turkey (Türkiye)
- Volunteers
- 162 people
- Sponsor
- Baskent University
Premenopausal Breast Cancer, Breast Cancer
Ovarian Reserve in Premenopausal Breast Cancer
This is a translational, mutlicentre study. The aim of this study is to determine whether pre-treatment levels of hormones predict ovarian follicular reserve post adjuvant or neoadjuvant chemotherapy for breast cancer and…
- Trial name
- NCT01726322
- Where
- 10 sites in Ireland
- Volunteers
- 216 people
- Sponsor
- Cancer Trials Ireland
Infertility, Polycystic Ovary Syndrome
A New Algorithm to Predict Ovarian Age
To collect data of clinical, biochemical and 3D-ultrasonographic parameters of a population of fertile women aged 18-55 in order to design a new algorithm able to predict ovarian age and to evaluate the reliability of a…
- Conditions
- Infertility, Polycystic Ovary Syndrome, Premature Ovarian Failure (POF), Ovarian Cysts
- Trial name
- OvAge (NCT02086318)
- Testing
- OvAge assessment
- Where
- Italy
- Volunteers
- 720 people, healthy volunteers welcome
- Sponsor
- University Magna Graecia
Breast Cancer
Study of Preservation of Ovarian Reserve During Chemotherapy for Young Breast Cancer Patients
The purpose of this study is to assess efficacy of gonadotropin-releasing hormone agonist (goserelin) on the preservation of ovarian reserve function in young breast cancer patients treated with (neo)adjuvant chemotherapy by…
- Trial name
- NCT02430103
- Testing
- Goserelin 3.6 MG
- Where
- China
- Volunteers
- 349 people
- Sponsor
- Peking University People's Hospital
Ovarian Reserve
Predictors of Ovarian Reserve in Infertile Women
Patients will be subjected to: A. Clinical evaluation including history and examination B. Ultrasonographic evaluation of Ovarian Morphometry: Patients will be evaluated in early follicular phase of the menstrual flow (cycle's…
- Trial name
- NCT02896023
- Testing
- human menopausal gonadotropin
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Cairo University
Benign Uterine Disease
Impact of Opportunistic Salpingectomy on Ovarian Reserve in Patients Undergoing Laparoscopic Hysterectomy
Recently, many gynecologic oncologists proposed that surgeons should consider opportunistic salpingectomy to prevent ovarian cancer for all patients undergoing hysterectomy for benign disease.
- Trial name
- NCT01893086
- Testing
- LH alone, LH with opportunistic salpingectomy
- Where
- 3 sites in South Korea
- Volunteers
- 68 people
- Sponsor
- CHA University
Infertility
Growth Hormone to Improve the Clinical Outcome of Assisted Fertility in Young Patients With Decreased Ovarian Reserve
This study was a prospective randomized controlled trial. Patients aged <35 years with decreased clinical reserve function (AFC<5, Follicle stimulating hormone > 10miu/ml, Anti-mullerian hormone < 1.1μg/L) and receiving IVF/ICSI…
- Trial name
- NCT05585177
- Testing
- Growth hormone
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Nanjing University
Diminished Ovarian Reserve (DOR)
Multi-Site Cortical Puncture for DOR
A multicenter, prospective, randomized controlled clinical trial. The target population consists of patients undergoing IVF/ICSI artificial reproduction who plan to undergo ovarian stimulation and embryo retrieval (DOR) within 4…
- Trial name
- MSCPD (NCT07568639)
- Testing
- multiple ovarian cortex punctures, routine oocyte retrieval procedure
- Where
- 7 sites in China
- Volunteers
- 214 people
- Sponsor
- First Affiliated Hospital of Guangxi Medical University
Infertility, Infertility (IVF Patients)
Growth Hormone and Dehydroepiandrosterone Role in Vitro Fertilization
The goal of this study is to evaluate the role of Somatropin and Dehydroepiandrosterone (DHEA) on ovarian reserve parameters and intracytoplasmic sperm injection (ICSI) outcome in poor ovarian responder.
- Trial name
- NCT07323329
- Testing
- Somatropin (4IU for 1 month) plus, folic acid 400 mcg per day., DHEA plus folic acid 400mcg per day, control group
- Where
- Egypt
- Volunteers
- 165 people
- Sponsor
- Beni-Suef University
Pregnancy, Ovarian
Biomarkers of Ovarian Reserve and Correlation With IVF Treatments
Retrospective study to evaluate the correlation between AFC, FSHb, AMH and IVF outcomes of 347 cycles performed with three different protocols.
- Trial name
- NCT02442895
- Where
- Italy
- Volunteers
- 236 people
- Sponsor
- U.O.S. Procreazione Medicalmente Assistita e Congelamento Gameti
Ovarian Cysts
The Effect of Laparoscopic Surgery on Ovarian Reserve According to Cyst Types
The aim of our study is to compare the effect of laparoscopic ovarian cystectomy on ovarian reserve in terms of different cyst types.
- Trial name
- NCT05054946
- Testing
- Laparoscopic cystectomy
- Where
- Turkey (Türkiye)
- Volunteers
- 55 people
- Sponsor
- Ege University
Gynecologic Operations, Anti-Mullerian Hormone
The Impact of Gynecological Surgery on Ovarian Function in Women of Reproductive Age: Postoperative Changes of Serum Anti-Müllerian Hormone (AMH)
Besides the removal of lesions, the purpose of surgeries has been extended to the improvement of quality of life after procedures. Minimally invasive surgeries enabled women to experience less pain, less hospital days.
- Conditions
- Gynecologic Operations, Anti-Mullerian Hormone, Ovarian Reserve
- Trial name
- NCT00928044
- Volunteers
- 330 people, healthy volunteers welcome
- Sponsor
- Samsung Medical Center
Infertility
Autologous Endometrial Coculture (AECCT)
The purpose of this study is to determine if the use of Autologous Endometrial Coculture (AECC) in young in vitro fertilization (IVF) patients with poor ovarian reserve improves pregnancy outcome.
- Trial name
- AECCT (NCT01472861)
- Testing
- AECC (Autologous endometrial coculture), no endometrial biopsy or Autologous endometrial coculture (AECC) performed
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
Ovarian Reserve, Acupuncture Therapy
Clinical Efficacy of Acupuncture on the Liver Meridian in Women With Diminished Ovarian Reserve
Diminished ovarian reserve (DOR) refers to a decrease in the number and quality of oocytes in the ovary, which results in impaired ovarian function and decreased fertility.
- Conditions
- Ovarian Reserve, Acupuncture Therapy, Meridian
- Trial name
- GJZLLCCBGNXJ (NCT05743218)
- Testing
- electropuncture
- Where
- China
- Volunteers
- 198 people
- Sponsor
- The First Affiliated Hospital of Hunan University of Traditional Chinese Medicine
VITAMIN D Disorders
Serum Vitamin D Level and Its Association With Ovarian Reserve and IVF Outcome
Vitamin D has a major play in bone and calcium metabolism. Vitamin D deficiency (below 20 ng/ml) has also been linked to adverse health outcomes such as malignancy, cardiovascular disease, immune functioning, and glucose…
- Trial name
- NCT02317718
- Testing
- monitor reproductive outcome
- Where
- United Arab Emirates
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Fakih IVF Fertility Center
Diminished Ovarian Reserve (DOR)
Testing Herbal Pretreatment For IVF Success In Women With Low Ovarian Reserve
The goal of this clinical trial is to learn if a traditional Chinese herbal pretreatment can improve pregnancy outcomes in infertile women with diminished ovarian reserve (DOR) who are undergoing in vitro fertilization (IVF) or…
- Trial name
- PRIME (NCT07347340)
- Testing
- Bushen Tongzhi Formula
- Where
- China
- Volunteers
- 348 people
- Sponsor
- Peking Union Medical College Hospital
Breast Cancer
A Pilot Observational Study to Assess Changes in Biochemical Parameters of Ovarian Reserve With Chemotherapy
Premenopausal women who are diagnosed with breast cancer are frequently treated with chemotherapy. Chemotherapy can affect the ovaries, and the effects can range from temporary loss of menstrual periods to permanent menopause.
- Trial name
- NCT00644683
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- Lynn Henry
Uterine Artery Ligation, Ovarian Reserve
Serum Antimullerian Hormone Levels in Patients Who Underwent Uterine Artery Ligation
Investigators would like to see the amh values after uterine artery ligation
- Trial name
- NCT03896243
- Testing
- Uterine artery ligation (UAL)
- Where
- Turkey (Türkiye)
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
Breast Cancer, Fertility
Investigating the Impact of Tamoxifen Therapy on Ovarian Aging
Ovarian toxicity is a well-described side effect of traditional chemotherapy in premenopausal women receiving treatment for early stage breast cancer.
- Trial name
- NCT01384526
- Where
- United States
- Volunteers
- 266 people
- Sponsor
- University of California, San Francisco
Ovarian Insufficiency, Radiation Exposure
Effect of Radioiodine Therapy on Ovarian Reserve in Female Patients With Differentiated Thyroid Cancer
Thyroid carcinoma is the most common endocrine malignancy. Surgery is the standard therapeutic approach for patients with differentiated thyroid carcinoma (DTC), followed by radioiodine (RAI) therapy if indicated.
- Trial name
- NCT04396158
- Testing
- radioactive iodine
- Volunteers
- 38 people
- Sponsor
- Assiut University