Clinical trials: Out-Of-Hospital Cardiac Arrest
Out-Of-Hospital Cardiac Arrest
Sex-unique Disparities in Survival and Resuscitation After Out-of-hospital Cardiac Arrest - a Danish Analysis
The goal of this observational study is to investigate characteristics in out-of-hospital cardiac arrests (OHCA) related to sex differences.
- Trial name
- NCT05583084
- Testing
- Investigation
- Volunteers
- 27,000 people
- Sponsor
- Prehospital Center, Region Zealand
Out-Of-Hospital Cardiac Arrest, Infarction, Myocardial
Post-ROSC Electrocardiogram After Cardiac arrEst
PEACE study retrospectively evaluate patients who suffered an out-hospital cardiac arrest (OHCA) and who underwent a coronary angiography, enrolled in the registry of the Province of Pavia (Italy), Ticino Region (Switzerland)…
- Trial name
- PEACE (NCT04096079)
- Volunteers
- 1,000 people
- Sponsor
- Fondazione IRCCS Policlinico San Matteo di Pavia
Out-Of-Hospital Cardiac Arrest, Oxygen Toxicity
ORI to Reduce Hyperoxia After Out Hospital Cardiac Arrest
The investigator's research proposal is a randomized controlled study evaluating two different monitoring strategies to titrate FiO2 in order to rapidly and safely achieve optimal SatO2 targets during early ROSC of non-traumatic…
- Trial name
- ORI-ONE (NCT03653325)
- Testing
- ORI measurement, oxygen saturation measurement
- Where
- 2 sites in Belgium
- Volunteers
- 100 people
- Sponsor
- Centre Hospitalier Universitaire Saint Pierre
Cardiac Arrest, Cardiopulmonary Arrest
Lowlands Saves Lives: A Randomized Trial Comparing CPR-quality Between Face-to-face vs. Lifesaver VR Training
The objective of the Lowlands Saves Lives trial is to compare the quality of cardiopulmonary resuscitation (CPR) between face-to-face versus Lifesaver Virtual Reality smartphone application trained participants using a randomized…
- Conditions
- Cardiac Arrest, Cardiopulmonary Arrest, Out-Of-Hospital Cardiac Arrest
- Trial name
- NCT04013633
- Testing
- Lifesaver virtual reality training, Face-to-face training
- Where
- Netherlands
- Volunteers
- 381 people, healthy volunteers welcome
- Sponsor
- Radboud University Medical Center
Cardiac Arrest
Head-up Position and High Quality Cardiopulmonary Resuscitation in OHCA
Elevation of the head and thorax, also known as Head-up cardiopulmonary resuscitation (HUP CPR), has been studied extensively in pigs in ventricular fibrillation (VF).
- Trial name
- GRAVITY (NCT03996616)
- Testing
- Head UP Position, Impedance Threshold Device, New Automated CPR
- Where
- 2 sites in France
- Volunteers
- 126 people
- Sponsor
- University Hospital, Grenoble
Out-of-hospital Cardiac Arrest
German Cardiac Arrest Registry
In Germany, 70.000 to 100.000 patients suffer from out-of-hospital cardiac arrest (OHCA) every year. More than half of these are due to cardiac causes.
- Trial name
- G-CAR (NCT05142124)
- Where
- 25 sites in Germany
- Volunteers
- 400 people
- Sponsor
- Leipzig Heart Science gGmbH
Cardiac Arrest (CA), Cardiogenic Shock
On Scene ECPR in Ostrava
On-scene extracorporeal pulmonary resuscitation (ECPR) for out-of-hospital cardiac arrest (OHCA) seems to speed up the start of extracorporeal membrane oxygenation (ECMO) and shorten low flow during cardiopulmonary resuscitation…
- Trial name
- NCT07374289
- Testing
- Prehospital ECMO cannulation on scene of cardiac arrest, Transfer with ongoing mechanical chest compression to hospital followed by hospital ECMO cannulation
- Where
- 2 sites in Czechia
- Volunteers
- 90 people
- Sponsor
- University Hospital Ostrava
Out-Of-Hospital Cardiac Arrest, Cardiac Arrest
Steroid Treatment After Resuscitated Out-of-Hospital Cardiac Arrest
Comatose patients resuscitated from Out-of-Hospital Cardiac Arrest (OHCA) often develop a complicated systemic inflammatory response and have a poor prognosis with neurological damage being the most common cause of death.
- Conditions
- Out-Of-Hospital Cardiac Arrest, Cardiac Arrest, Cardiac Arrest With Successful Resuscitation, Post Cardiac Arrest Syndrome
- Trial name
- STEROHCA (NCT04624776)
- Testing
- Methylprednisolone, Isotonic saline
- Where
- 2 sites in Denmark
- Volunteers
- 158 people
- Sponsor
- Christian Hassager
Out-Of-Hospital Cardiac Arrest
Tissue Oxygenation During Cardiopulmonary Resuscitation as a Predictor of Return of Spontaneous Circulation
The main objective of the trial is to find out if there is correlation between cerebral and skeletal muscle oxygenation values during cardiopulmonary resuscitation and if these values can predict return of spontaneous…
- Trial name
- NCT04058925
- Testing
- NIRS device
- Where
- Slovenia
- Volunteers
- 30 people
- Sponsor
- Miha Košir
Cardiac Complications, Sudden Cardiac Arrest
The Study Aims to Investigate the Frequency and Clinical Characteristics of Out-of-hospital Cardiac Arrests (OHCA) Occurring in Poland in 2023. This Research Seeks to Provide a Comprehensive Analysis of OHCA Incidents Across the Country, Focusing on Their Prevalence and the Associated Clinical fe
1. Objective According to the 2021 European Resuscitation Council (ERC) Guidelines, sudden cardiac arrest is the third leading cause of death in Europe.
- Conditions
- Cardiac Complications, Sudden Cardiac Arrest, Cardiac Diseases, Cardiac Arrest (CA)
- Trial name
- OHCA_PL (NCT06948266)
- Where
- Poland
- Volunteers
- 100,000 people
- Sponsor
- Medical University of Gdansk
Cardiac Arrest
Pragmatic Airway Resuscitation Trial
The primary objective of the trial is to determine if 72-hour survival after out-of-hospital cardiac arrest (OHCA) is improved with initial endotracheal intubation (ETI) over initial laryngeal tube (LT) airway management…
- Trial name
- PART (NCT02419573)
- Testing
- Endotracheal Intubation, Laryngeal Tube (King)
- Where
- 6 sites in United States
- Volunteers
- 3,004 people
- Sponsor
- University of Alabama at Birmingham
Heart Arrest, Ventricular Fibrillation
AED Use in Out-of-Hospital Cardiac Arrest: A New Algorithm Named "One Shock Per Minute"
The aim of the trial is to evaluate a new AED algorithm that proposes a new timeline between the time devoted to administer a defibrillation shock, and the time devoted to chest compressions.
- Trial name
- DEFI2005 (NCT00139542)
- Testing
- One shock per minute AED protocol, Guidelines 2000 AED protocol
- Where
- France
- Volunteers
- 5,107 people
- Sponsor
- Fire Brigade Of Paris Emergency Medicine Dept
Arrest Cardio Respiratory
Free Iron and Out of Hospital Cardiac Arrest
Out of hospital cardiac arrest is associated with a poor prognosis. The aim of this study is to provide a better understanding of perturbations of iron metabolism after cardiac arrest and to analyze the impact on clinical…
- Trial name
- DESFER (NCT03491670)
- Where
- France
- Volunteers
- 25 people
- Sponsor
- University Hospital, Brest
Post-Cardiac Arrest Syndrome
Xenon for Neuroprotection During Post-Cardiac Arrest Syndrome in Comatose Survivors of an Out of Hospital Cardiac Arrest
XePOHCAS: Prospective, randomized, multicenter interventional trial in adult subjects with out-of-hospital cardiac arrest comparing treatment with standard-of-care post-cardiac arrest intensive care (which is targeted temperature…
- Trial name
- XePOHCAS (NCT03176186)
- Testing
- Xenon
- Where
- 10 sites in United States, Denmark
- Volunteers
- 1,436 people
- Sponsor
- Invero Pharma, Inc.
Cardiac Arrest, Out-Of-Hospital
Prehospital ECPR in Moravia Silesia Region
Cardiopulmonary resuscitation (CPR) for out-of-hospital cardiac arrest (OHCA) in specific cases could be improved by Extracorporeal membrane oxygenation (ECMO; ECPR).
- Trial name
- 01-Pain (NCT07041086)
- Testing
- Extracorporeal membrane oxygenation (ECMO)
- Where
- 2 sites in Czechia
- Volunteers
- 100 people
- Sponsor
- University Hospital Ostrava
Out-Of-Hospital Cardiac Arrest, Resuscitation Registry
European Registry of Cardiac Arrest Study Two
This study will evaluated the epidemiology and the outcome of patients suffering out-of-hospital cardiac arrest in 27 european nations. The special focus in the EuReCa TWO study is on bystander CPR.
- Trial name
- EuReCa TWO (NCT03130088)
- Testing
- no intervention planed
- Where
- Germany
- Volunteers
- 35,000 people
- Sponsor
- German Resuscitation Registry
Out-of-Hospital Cardiac Arrest
Predicting Long-term Outcomes After Cardiac Arrest by Using Serum NGAL
This study was performed to determine the prognosis of patients after cardiac arrest using serum markers called NGAL. The initial NGAL values of patients with post-cardiac arrest syndrome are checked by blood tests, and the…
- Trial name
- NCT03615300
- Testing
- serum NGAL
- Where
- South Korea
- Volunteers
- 73 people
- Sponsor
- Uijeongbu St. Mary Hospital
Cardiac Arrest
Washington Study of Hemofiltration After Out-of-Hospital Cardiac Arrest
The purpose of this study is to assess the feasibility of hemofiltration in patients resuscitated from cardiac arrest. Cardiac arrest is the loss of mechanical activity of the heart including the loss of detectable pulse, or…
- Trial name
- NCT01509040
- Testing
- Standard Care, Low Volume Hemofiltration, High Volume Hemofiltration
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- University of Washington
Out-of-hospital Cardiac Arrest
Tracheal Intubation vs. Bag-valve-mask Ventilation in Patients With Out-of-Hospital Cardiac Arrest _ CAAM STUDY
The aim of this study is to improve the management of patients in cardiac arrest, and this by comparing two initial airway management methods: Tracheal intubation and bag-valve-mask ventilation.
- Trial name
- CAAM (NCT02327026)
- Testing
- bag-valve-mask ventilation, tracheal intubation
- Where
- France
- Volunteers
- 2,043 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Heart Arrest, Cardiac Arrest
Mechanisms of Ultra-acute Hyperglycemia After Successful Resuscitation From Out-of-hospital Cardiac Arrest
The aim of the study is to describe the mechanisms of ultra-acute hyperglycemic response after return of spontaneous circulation (ROSC) in patients suffering out-of-hospital cardiac arrest.
- Trial name
- NCT01968148
- Where
- 2 sites in Finland
- Volunteers
- 30 people
- Sponsor
- Helsinki University Central Hospital