Clinical trials: Out-Of-Hospital Cardiac Arrest
Out-of-hospital Cardiac Arrest
Evaluation of Out-of-Hospital Cardiac Arrest Recognition by Non-physicians Dispatchers in a French Emergency Dispatch Call Center
The purpose of this study is to measure an improvement in the detection rate of cardiac arrest (CA) in the Dispatch Center as a result of debriefings and repeated trainings for non-medical operators who receive emergency calls.
- Trial name
- OCAR (NCT01992419)
- Where
- France
- Volunteers
- 300 people
- Sponsor
- Fire Brigade Of Paris Emergency Medicine Dept
Cardiopulmonary Arrest
Compare Outcomes of CPR Between the Video-laryngoscopy (VL) Users and the Direct-laryngoscopy (DL) Users
This is a clinical study based on the analysis of video-clip data of cardiopulmonary resuscitation (CPR) and clinical data for out of hospital cardiac arrest patients between 2011 and 2015.
- Trial name
- NCT03256019
- Testing
- Endotracheal Intubation
- Volunteers
- 600 people
- Sponsor
- Konkuk University Medical Center
out-of Hospital Cardiac Arrest
Pre-Hospital Cerebral Oxygenation and End-Tidal CO2 During Cardiopulmonary Resuscitation (CPR)
Cerebral saturation will be measured pre-hospital during an out-of hospital cardiac arrest with O3TM regional oximetry for Root® (Masimo®).
- Trial name
- CopernicusIb (NCT02850237)
- Where
- Belgium
- Volunteers
- 30 people
- Sponsor
- Hasselt University
Out of Hospital Cardiac Arrest
A Multi-centre Survey of Epidemiology, Treatment and Outcome of Patients Suffering an Out-of-hospital Cardiac Arrest
There is considerable variation in the incidence of out-of-hospital cardiac arrest (OHCA) across Europe. The likelihood of attempted resuscitation also varies.
- Trial name
- EuReCaONE (NCT02236819)
- Where
- Germany
- Volunteers
- 10,682 people
- Sponsor
- German Resuscitation Registry
Cardiac Arrest, Sudden
AED Log Analysis of 19 Cases in Out-of-hospital Environment
The study performed to demonstrate a reasonable assurance of safety and effectiveness of the Heart Guardian HR-501 when used in an out-of-hospital environment.
- Trial name
- NCT03969797
- Testing
- RADIAQBIO Heart Guardian HR-501
- Where
- South Korea
- Volunteers
- 19 people
- Sponsor
- RadianQbio
Out-of-hospital Cardiac Arrest (OHCA)
Application of Transesophageal Echocardiography in Pre-hospital Cardiac Arrest Patients
The Use of Point-of-Care Ultrasound (POCUS), Transthoracic Echocardiography (TTE), and Transesophageal Echocardiography (TEE) in Cardiac Arrest and Acute Coronary Syndrome Patients Studies have shown that POCUS can rapidly change…
- Trial name
- TAPCAP (NCT06672315)
- Testing
- transesophageal echocardiography
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- Jen-Tang Sun
Cardiac Arrest (CA), Cardiogenic Shock
On Scene ECPR in Ostrava
On-scene extracorporeal pulmonary resuscitation (ECPR) for out-of-hospital cardiac arrest (OHCA) seems to speed up the start of extracorporeal membrane oxygenation (ECMO) and shorten low flow during cardiopulmonary resuscitation…
- Trial name
- NCT07374289
- Testing
- Prehospital ECMO cannulation on scene of cardiac arrest, Transfer with ongoing mechanical chest compression to hospital followed by hospital ECMO cannulation
- Where
- 2 sites in Czechia
- Volunteers
- 90 people
- Sponsor
- University Hospital Ostrava
Out-Of-Hospital Cardiac Arrest
Cardiac Arrest in Residential Areas With Mobile First-responder Activation
The study aims to increase proportions of bystander defibrillation during out-of-hospital cardiac arrest (hereof referred to as cardiac arrest) in residential areas with a high density of cardiac arrests.
- Trial name
- CARAMBA (NCT04446585)
- Testing
- Automated External Defibrillator (AED), Training in cardiopulmonary resuscitation and AED use, Activation of citizen responders
- Where
- Denmark
- Volunteers
- 260 people
- Sponsor
- Emergency Medical Services, Capital Region, Denmark
Out-of-hospital Cardiac Arrest
Targeted Hypothermia Versus Targeted Normothermia After Out-of-hospital Cardiac Arrest
ILCOR guidelines recommend Target Temperature Management (TTM) to between 32°C and 36°C after out-of-hospital cardiac arrest, based on low quality evidence.
- Trial name
- TTM-2 (NCT02908308)
- Testing
- Targeted temperature management to 33°C, Standard care with early treatment of fever
- Where
- 60 sites in United States, Australia and 12 more
- Volunteers
- 1,900 people
- Sponsor
- Helsingborgs Hospital
Out-of-hospital Cardiac Arrest (OHCA)
Ventilation Performance and Feedback Simulation Trial
The study "Understanding the Effect of Feedback on Ventilation Performance of Rescuers in a Simulation Trial" will address treatments administered by Emergency Medical Services (EMS) during cardiopulmonary resuscitation (CPR) in…
- Trial name
- VENT-SIM (NCT07352709)
- Testing
- Real-time feedback
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- University of Texas Southwestern Medical Center
Cardiac Arrest
Evaluation of Muscle StO2 as a Prognostic Factor After Out of Hospital Cardiac Arrest
Out of hospital cardiac arrest is a major health problem. Prognosis is still poor even after return to spontaneous circulation. The pathophysiology of cardiac arrest implies ischemia-reperfusion and sepsis like syndrome.
- Trial name
- NCT01073098
- Testing
- Vascular occlusion test
- Where
- 2 sites in France
- Volunteers
- 51 people
- Sponsor
- Department of Clinical Research and Innovation
Out of Hospital Cardiac Arrest
Ambulance Clinicians' Experiences of Attending OHCA in Children
This research will explore ambulance clinicians' experiences of attending out of hospital cardiac arrest (OHCA) incidents involving children. OHCA occurs when the heart stops beating.
- Trial name
- NCT06922019
- Where
- United Kingdom
- Volunteers
- 2,137 people, healthy volunteers welcome
- Sponsor
- University of Warwick
Cardiac Arrest, Out-Of-Hospital Cardiac Arrest
Early Initiation of Extracorporeal Life Support in Refractory OHCA
Despite adequate conventional cardiopulmonary resuscitation (CCPR) and attempted defibrillation, a considerable number of patients in cardiac arrest fail to achieve sustained return of spontaneous circulation.
- Conditions
- Cardiac Arrest, Out-Of-Hospital Cardiac Arrest, Sudden Cardiac Death
- Trial name
- INCEPTION (NCT03101787)
- Testing
- Extracorporeal cardiopulmonary resuscitation (ECPR)
- Where
- 10 sites in Netherlands
- Volunteers
- 134 people
- Sponsor
- Maastricht University Medical Center
Cardiac Arrest, Out-Of-Hospital
Evaluation of Updated Procedure for Management of Refractory Out-of-hospital Cardiac Arrests
ECPR is a technique that has been rapidly developed in many cardiac arrest specialized centers In 2013, a specific management protocol was developed for patients in refractory out-of-hospital cardiac arrest around Nancy, France.
- Trial name
- ACEP-V2 (NCT06603649)
- Testing
- ECPR for out-of-hospital cardiac arrest
- Where
- France
- Volunteers
- 150 people
- Sponsor
- Central Hospital, Nancy, France
Out of Hospital Cardiac Arrest
Time-differentiated Therapeutic Hypothermia
The purpose of this study is to determine if 48 hours of mild therapeutic hypothermia following out of hospital cardiac arrest gives a better cerebral outcome compared to 24 hours therapeutic hypothermia.
- Trial name
- TTH48 (NCT01689077)
- Testing
- Therapeutic hypothermia
- Where
- 10 sites in Belgium, Denmark and 4 more
- Volunteers
- 355 people
- Sponsor
- University of Aarhus
Out-Of-Hospital Cardiac Arrest, Post Cardiac Arrest Syndrome
Pre-hospital Post ROSC Care: Are we Achieving Our Targets?
Rational: Out of hospital cardiac arrest is a devastating event with a high mortality. Survival rates have increased over the last years, with the availability of AED's and public BLS.
- Conditions
- Out-Of-Hospital Cardiac Arrest, Post Cardiac Arrest Syndrome, Emergency Medical Services
- Trial name
- POP-ROC (NCT04339257)
- Volunteers
- 175 people
- Sponsor
- University Medical Center Groningen
Out-of-Hospital Cardiac Arrest
Early Gastric Decompression During Advanced Cardiopulmonary Resuscitation (EGD_ACLS)
This study aimed to identify the effect of early gastric decompression on the improvement of circulation in arrest patients during cardiopulmonary resuscitation at the clinical setting of emergency department.
- Trial name
- EGD_ACLS (NCT02391857)
- Testing
- Gastric decompression
- Where
- South Korea
- Volunteers
- 40 people
- Sponsor
- Konkuk University Medical Center
Out-Of-Hospital Cardiac Arrest
The Impact of Aortic Valve Compression During Cardio-pulmonary Resuscitation on Patients With Out-of-hospital Cardiac Arrest
Purpose: This study aims to find out if the current way of performing chest compressions during resuscitation for patients who have suffered a cardiac arrest outside of the hospital is affecting their chances of recovery.
- Trial name
- AVC in OHCA (NCT05932784)
- Testing
- transesophageal echocardiography
- Where
- Taiwan
- Volunteers
- 76 people
- Sponsor
- Far Eastern Memorial Hospital
Cardiac Arrest With Successful Resuscitation, Cardiac Arrest, Cause Unspecified
Optimization of Transport and Use of a Mobile ECMO Team in Patients With Sudden Cardiac Arrest in the Moravian-Silesian Region
This study evaluates the feasibility of implementing a mobile extracorporeal membrane oxygenation (ECMO) team and optimizing patient transport logistics.
- Trial name
- NCT07009652
- Testing
- Extracorporeal cardiopulmonary resuscitation (ECPR)
- Where
- 2 sites in Czechia
- Volunteers
- 100 people
- Sponsor
- University Hospital Ostrava
Emergency Medical Service, Out-of-Hospital Cardiac Arrest
Venous Injection Compared To intraOsseous Injection During Resuscitation of Patients With Out-of-hospital Cardiac Arrest
Overall survival of patients after out-of-hospital cardiac arrest (*OHCA*) is less than 10% worldwide and in Taiwan. Interventions provided by the emergency medical system (*EMS*) before arrival at the hospital are of paramount…
- Conditions
- Emergency Medical Service, Out-of-Hospital Cardiac Arrest, Vascular Access, Intraosseous Access
- Trial name
- VICTOR (NCT04135547)
- Testing
- intra-osseous access vs. intra-venous access
- Where
- Taiwan
- Volunteers
- 1,732 people
- Sponsor
- National Taiwan University Hospital