Clinical trials: Osteoporosis Secondary
Osteoporosis
Assessment of TRACP-5b in Primary and Secondary Osteoporosis
Assessment of the TRACP-5b level in 1ry OP and 2ry OP such as RA and seronegative spondylitis, that may help in surrogating the use of BMD.
- Trial name
- NCT05103592
- Testing
- Tartrate- resistant Acid Phosphatase marker
- Volunteers
- 84 people
- Sponsor
- Assiut University
Osteoporosis, Secondary Hyperparathyroidism
Calcium and Vitamin D Malnutrition in Elderly Women
This study is designed to test whether calcium supplementation alone or calcium plus vitamin D reduces the incidence of fractures, reduces high parathyroid secretory activity, and halts bone loss in a population-based sample of…
- Trial name
- NCT00352170
- Testing
- calcium supplementation, calcium and vitamin D3 supplementation
- Volunteers
- 1,180 people, healthy volunteers welcome
- Sponsor
- Creighton University
Osteoporosis Secondary, Diabetes Mellitus, Type 1
the Type ONe dIabetic Bone Collaboration Study
In this cross-sectional clinical study, we will examine the bones of 111 Type 1 Diabetes (T1D) patients and 37 age-matched healthy controls with the aim of describing a T1D Bone Phenotype.
- Trial name
- TONICS (NCT05673837)
- Where
- Denmark
- Volunteers
- 148 people, healthy volunteers welcome
- Sponsor
- Odense University Hospital
Breast Cancer, Prostate Cancer
Pilot Study of Secondary Causes of Osteopenia/Osteoporosis in Adults With Breast and Prostate Cancer
The investigators hypothesis is that secondary causes of bone loss are prevalent in patients with breast and prostate cancer, and those patients with secondary causes of bone loss are at higher risk for treatment related bone…
- Conditions
- Breast Cancer, Prostate Cancer, Osteopenia, Osteoporosis
- Trial name
- NCT01277562
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- City of Hope Medical Center
Postmenopausal Osteoporosis, Postmenopause
Frequency of Hyperparathyroidism in Postmenopausal Osteoporosis and Its Treatment
Recently, an increase in the prevalence of hyperparathyroidism and hypovitaminosis D in postmenopause women has been occurring in Mexico and the world.
- Conditions
- Postmenopausal Osteoporosis, Postmenopause, Hyperparathyroidism, Secondary, Hypovitaminosis D
- Trial name
- NCT05347082
- Testing
- Cholecalciferol
- Where
- Mexico
- Volunteers
- 47 people
- Sponsor
- Hospital Regional 1o de Octubre
Osteoporosis
Osteoporosis Disease Management Demonstration Project (0000-040)
The purpose of the study is to evaluate the impact disease management interventions in treatment compliance among post-fracture and osteoporosis patients.
- Trial name
- NCT00145067
- Testing
- Disease Management Assessment
- Volunteers
- 230 people
- Sponsor
- Merck Sharp & Dohme LLC
Secondary Osteoporosis, Spinal Cord Injury
The Efficacy of Denosumab in Incomplete Patients Spinal Cord Injury
The purpose of this study is to determine the usefulness of a drug, denosumab, to prevent the loss of bone in participants legs due to SCI.
- Trial name
- NCT03029442
- Testing
- Denosumab (Prolia)
- Where
- 2 sites in United States
- Volunteers
- 5 people
- Sponsor
- James J. Peters Veterans Affairs Medical Center
Secondary Osteoporosis
Efficacy of Zoledronic Acid + Colaren vs Zoledronic Acid + Conventional Treatment for Osteoporosis in HIV+ and HIV- Men
Clinical trial to assess the effectiveness of the supplement Colaren® associated with zoledronic acid 4mg/annually in the treatment of osteoporosis secondary, compared to standard treatment plus zoledronic acid 4mg/annually.
- Trial name
- OSZCO (NCT03930992)
- Testing
- Colaren in HIV positive, standard treatment in HIV positive, Colaren in HIV negative
- Where
- Mexico
- Volunteers
- 30 people
- Sponsor
- University of Guadalajara
Osteoporosis
Efficacy of Oral Ibandronate in Osteoporosis
There has been no comparative data between oral ibandronate and oral ibandronate plus active vitamin D
- Trial name
- NCT03186131
- Testing
- Ibandronate, Oral Ibandronate and Vitamin D
- Where
- Japan
- Volunteers
- 100 people
- Sponsor
- Shinshu University
Osteoporosis
Secondary Prevention of Osteoporotic Fractures: a Multiple Center Fracture Liaison Service in Greece
This is multiple center, prospective study aiming to investigate the tracking and outcome of patients attending Greek General hospitals with low-trauma fractures.
- Trial name
- NCT02637180
- Testing
- anti-osteoporotic medication
- Where
- 4 sites in Greece
- Volunteers
- 397 people
- Sponsor
- Hellenic Society for the Study of Bone Metabolism
Osteoporosis, Renal Osteodystrophy
The Effects of 12-months of Denosumab on Bone Density in Prevalent Kidney Transplant Recipients
This is a Phase 2 Multi-Center Clinical Trial (safety and effectiveness trial) in 60 patients (40 denosumab; 20 placebo) who have had a kidney transplant for 12-months or longer with more than 30% of kidney function.
- Conditions
- Osteoporosis, Renal Osteodystrophy, Kidney Transplant; Complications
- Trial name
- ProliaKTx (NCT03960554)
- Testing
- Denosumab Inj 60 mg/ml
- Where
- 3 sites in United States
- Volunteers
- 8 people
- Sponsor
- Thomas Nickolas, MD MS
Osteoporosis
Cancer and Osteoporosis Research With Alendronate and Lupron (C.O.R.A.L )
Multi-center,double blind randomized phase III placebo controlled study in 250 men with histologically proven prostate cancer with out bone metastases who are beginning ADT therapy and who will receive concomitant treatment with…
- Trial name
- NCT00236002
- Testing
- Alendronate
- Volunteers
- 182 people
- Sponsor
- Canadian Urology Research Consortium
Osteoporosis, Chronic Kidney Disease Mineral and Bone Disorder
Osteoporosis & Renal Disease: Research in Primary Health Care Services
Osteoporosis, a silent and multifactorial systemic skeletal disorder, severely compromises bone strength and significantly increases the risk of fragility fractures.
- Trial name
- NCT07848490
- Testing
- Fracture risk assessment tool (FRAX), Dual-Energy X-ray Absorptiometry (DXA)
- Where
- Portugal
- Volunteers
- 622 people
- Sponsor
- Universidade do Porto
Osteoporosis Secondary, Breast Cancer Females
Vitamin k, D-chiro Inositol and α-lactalbumin in Bone Homeostasis
In women with breast cancer undergoing adjuvant hormone therapy, the marked tissue hypoestrogenism induced by therapy with aromatase inhibitors and/or tamoxifen ± GnRH analogues causes a significant acceleration in bone mass…
- Trial name
- Synostea (NCT07256769)
- Testing
- Group 1: calcium carbonate/cholecalciferol, Group 2: Synostea® (calcium carbonate/cholecalciferol/vitamin K/α-lactalbumin/ d-chiro-inositol)
- Where
- 2 sites in Italy
- Volunteers
- 134 people
- Sponsor
- Regina Elena Cancer Institute
Osteoporotic Fractures, Osteoporosis
Stop At One Stockholm (SAOS)- Secondary Fracture Prevention Through Active Patient Identification and Staff Education.
This is a study on the effects of education on secondary fracture prevention in primary health care centers (PHCC) and referral from hospitals to these PHCC of patients with recent fragility fractures.
- Conditions
- Osteoporotic Fractures, Osteoporosis, Osteoporosis Risk
- Trial name
- SAOS (NCT04565743)
- Testing
- Support on dentification and treatment of patients with high risk of osteoporotic fractures
- Where
- Sweden
- Volunteers
- 38 people
- Sponsor
- Helena Salminen
Hemodyalysis, Kidney Tansplant
Assessment of Mineral and Bone Disorders in Kidney Transplant Recipients
This study aims to integrate bone measurements (including bone turnover markers (BTM), bone mineral density (BMD) measurement, vertebral fracture assessment (VFA), trabecular bone score (TBS) ) commonly used in the general…
- Conditions
- Hemodyalysis, Kidney Tansplant, Osteoporosis, CKD-MBD - Chronic Kidney Disease Mineral and Bone Disorder
- Trial name
- NCT07141043
- Where
- Romania
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Grigore T. Popa University of Medicine and Pharmacy
Osteoporosis With Current Fragility Fracture
Evaluation of an Osteoporosis Prevention Strategy in Women With Osteoporotic Fracture of the Upper Limb
Osteoporosis is a disease characterized by reduced bone mass and increased skeletal fragility, predisposing to an increased fracture risk.
- Trial name
- PREVOST (NCT01780012)
- Testing
- Osteoporosis prevention program
- Where
- France
- Volunteers
- 436 people
- Sponsor
- Hospices Civils de Lyon
Chronic Kidney Diseases, Hyperparathyroidism, Secondary
Analysis of Bone Microarchitecture With HR-pQCT of Patients With Chronic Kidney Disease (CKD) Candidates for Renal Transplantation
While the duration of renal transplant function has increased over the last decade kidney transplanted patients (KTP) still exhibit a fracture risk 4 times higher than in the general population.
- Trial name
- TRANSBONE (NCT02523209)
- Testing
- HR-pQCT, DEXA
- Where
- France
- Volunteers
- 102 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Spinal Fracture, Osteoporosis
Quality of Life After Vertebroplasty Versus Conservative Treatment in Patients With Painful Osteoporotic Vertebral Fractures
The purpose of this study is to determine whether percutaneous vertebroplasty is able to improve long-term quality of life in patients with pain secondary to osteoporotic vertebral fractures, compared to conventional medical…
- Conditions
- Spinal Fracture, Osteoporosis, Back Pain
- Trial name
- NCT00994032
- Testing
- percutaneous injection of cement into the vertebral body, Medical treatment
- Where
- Spain
- Volunteers
- 120 people
- Sponsor
- Hospital Clinic of Barcelona
Osteoporosis
Teriparatide (Forsteo) Treatment in Postmenopausal Women: Mechanism of Action
Previously the approach to treatment of osteoporosis has been to use medications which prevent excessive resorption of bone. More recently medications that build up new bone, i.e.
- Trial name
- Forsteo (NCT01293292)
- Testing
- Teriparatide
- Where
- United Kingdom
- Volunteers
- 19 people
- Sponsor
- Sheffield Teaching Hospitals NHS Foundation Trust