Clinical trials: Osteopenia, open to volunteers
Bone Loss, Jaw, Edentulous
Effectiveness of 3D-printed Patient-specific Resorbable Scaffolds for Maxillary Bone Regeneration
The objective of this study is to test the bone formation capacity of a 3D printed scaffold with a plastic material called Polycaprolactone (PCL), compared to the use of synthetic bone grafts, for bone formation in the maxilla or…
- Conditions
- Bone Loss, Jaw, Edentulous, Edentulous Mouth, Jaw Fractures
- Trial name
- OSTEOPRINT (NCT06773923)
- Testing
- PCL Scaffold, PTFE + Bio-Oss®
- Where
- Chile
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Universidad Austral de Chile
Osteoporosis, Osteopenia
Serum Myostatin and Irisin Levels in Postmenopausal Women: Association With Bone Mineral Density and Muscle Strength
This study aims to evaluate the relationship between serum myostatin and irisin levels and bone mineral density and muscle strength in postmenopausal women.
- Trial name
- MYOIRISIN (NCT07519551)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
Peri-Implantitis, Alveolar Bone Loss
Non-Surgical Treatment of Peri-Implantitis With Ultrasonic Carbon Tip
As the frequency of dental implants increases, the incidence of complications and peri-implant diseases also increases. Early diagnosis and treatment of the disease is important to prevent consequences up to implant loss.
- Trial name
- NCT06514677
- Testing
- Ultrasonic Carbon Tip, Titanium Curette
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Kutahya Health Sciences University
Low Bone Mineral Density, Muscle Oxygenation
Bone and Muscle Oxygenation in Military Test Pilots
This prospective, single-group interventional pilot study will evaluate the effects of a 12-week resistance and core stabilization exercise program on bone mineral density and resting muscle oxygenation in male military test…
- Trial name
- BMO-MTP (NCT07787143)
- Testing
- Supervised Resistance and Core Stabilization Exercise Program
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Emine Merve Ersever
Bone Substitutes, Alveolar Bone Grafting
Bone Augmentation Techniques in the Mandible Posterior Region
This study will compare three methods to rebuild lost bone in the back part of the lower jaw (posterior mandible) before dental implant placement.
- Trial name
- NCT06661447
- Testing
- Cortical Shell Bone Grafting
- Where
- Ecuador
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Universidad de Especialidades Espiritu Santo
Alveolar Bone Loss, Tooth Loss / Rehabilitation
Bone and Soft Tissue Healing After Socket Preservation With NOVAMag or Permamem Membranes
After tooth extraction, the surrounding bone and soft tissue may undergo dimensional reduction. Socket preservation involves placement of a bone graft into the extraction socket and coverage with a membrane to support healing…
- Conditions
- Alveolar Bone Loss, Tooth Loss / Rehabilitation, Alveolar Bone Grafting, Socket Preservation
- Trial name
- NCT07856693
- Testing
- NOVAMag Membrane, permamem Membrane, Alveolar Socket Preservation With an Allogeneic Bone Graft
- Where
- Croatia
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Zagreb
Obesity and Obesity-related Medical Conditions, Diabetes
Routine Validation and Reproducibility Testing of Laboratory Assays and Research Techniques Used for Endocrine, Cardiometabolic, and Musculoskeletal Disorder Research (VALD)
The purpose of this research study is to validate (check the accuracy of) laboratory assays, intravenous catheter insertion, and equipment or devices and their reproducibility, which is necessary to perform high quality research…
- Conditions
- Obesity and Obesity-related Medical Conditions, Diabetes, Atherosclerotic Disease, Heart Failure
- Trial name
- VALD (NCT07083557)
- Testing
- Endothelial cell collection
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Bettina Mittendorfer
Periodontal Disease, Periodontal Bone Loss
Laser Assisted Open Flap Debridement
The study involves the surgical treatment of patients with Stage I to III of periodontitis. Following completion of Steps 1 and 2 of periodontal therapy according to the EFP guidelines for the treatment of periodontitis, sites…
- Trial name
- LaserOpen (NCT07807215)
- Testing
- Mechanical Open Flap debridement, Laser assisted open flap debridement
- Where
- Italy
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Bari Aldo Moro
Cognitive Performance, Age-Related Macular Degeneration
Lutein, Zeaxathin, and Fish Oil Supplementation
The goal of this clinical trial is to learn the impact of lutein, zeaxanthin, and fish oil (LZF) supplementation in healthy adults.
- Conditions
- Cognitive Performance, Age-Related Macular Degeneration, Bone Loss
- Trial name
- NCT06489873
- Testing
- Active Comparator (Lutein, zeaxanthin, and fish oil supplement (LZF)
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Texas A&M University
Osteopenia, Osteoporosis
Calcium-Rich Food Versus Calcium Carbonate for Bone Health
This study will compare adherence, tolerability, safety, and treatment satisfaction between a calcium-rich food and a traditional calcium carbonate supplement in women ages 40 to 90 who are at increased risk for osteoporosis.
- Conditions
- Osteopenia, Osteoporosis, Bone Health in Perimenopausal Women, Menopause Related Conditions
- Trial name
- NCT07763509
- Testing
- 500 mg calcium from milk-derived minerals, Calcium Carbonate 500 MG
- Where
- United States
- Volunteers
- 217 people, healthy volunteers welcome
- Sponsor
- Cornell University
Periodontal Diseases, Periimplant Diseases
Markers of Bone Destruction and Oxidative Stress in Peri-implantitis
The aim of this study is to evaluate and compare the levels of bone resorption (RANKL, OPG) and oxidative stress (Nitrotyrosine, NQO1) markers, along with pro-inflammatory cytokines (IL-1β), in the saliva and peri-implant…
- Trial name
- NCT07397884
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Alveolar Bone Loss
Demineralized Dentin Allograft Versus Demineralized Dentin Autograft for Socket Preservation
This study is designed to evaluate and compare clinically and radiographically the effectiveness of Demineralized Dentin Allograft (DDA) versus Demineralized Dentin Autograft (Auto-DD) for preservation of alveolar ridge…
- Trial name
- NCT06457373
- Testing
- Demineralized Dentin Allograft, Demineralized Dentin Autograft
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Horus University
Horizontal Atrophy of Edentulous Alveolar Ridge
Crestal Bone Loss Around Narrow Diameter Implants Versus Standard Diameter Implants With Bone Augmentation in Horizontally Deficient Posterior Mandibular Sites.
Dental implant treatment, in many cases, may be impeded by anatomical limitations, such as narrow atrophic ridges. In order to overcome that, additional surgical procedures, such as guided bone regeneration, are often required to…
- Trial name
- NCT06221306
- Testing
- Dental implant: NDI, Dental implant: SDI
- Where
- Egypt
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Cairo University
Osteoporosis, Osteopenia
A Study Evaluating the Performance of Using AI Software and Chest X-rays to Screen for Osteoporosis as Compared to Standard DXA Scans in Patients 50 Years and Older
The goal of this study is to assess the performance of an artificial intelligence software (Osteo Signal) in detecting osteoporosis risk in adults 50 years and older.
- Trial name
- NCT07421713
- Testing
- Osteo Signal
- Where
- 3 sites in Netherlands, United Kingdom
- Volunteers
- 595 people, healthy volunteers welcome
- Sponsor
- Promedius Inc
Bone Loss, Alveolar
Evaluation of Bone Gain Using Customized 3D Zirconia Barrier Versus Titanium Mesh
Evaluation of clinical and radiographical amount of bone gained using customized 3D printed zirconia barrier compared to titanium mesh in combined ridge defect at the esthetic zone.
- Trial name
- NCT06559605
- Testing
- zirconia barrier, titanium mesh
- Where
- Egypt
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Cairo University
Alveolar Bone Atrophy, Alveolar Bone Grafting
Digital Planning and Clinical Assessment of the Treated Atrophic Posterior Maxilla With a Sinus Lift Procedure: a Cross-sectional Study.
Maxillary posterior area is the most challenging site for dental implant placement. Indeed, complex remodeling processes, resulting in changes of the maxillary sinus and shape of the alveolar ridge will cause difficulties in…
- Conditions
- Alveolar Bone Atrophy, Alveolar Bone Grafting, Peri-Implant Health, Sinus Floor Augmentation
- Trial name
- NCT07526337
- Where
- Lebanon
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Saint-Joseph University
Alveolar Bone Loss, Periodontal Diseases
Evaluation of the Effectiveness of Odontogenic Grafts Obtained From Human Teeth on Bone Formation
Tooth extraction triggers a cascade of biological events mediated by the local inflammatory response following surgical intervention and by the loss of masticatory stimulation to the periodontium.
- Conditions
- Alveolar Bone Loss, Periodontal Diseases, Periodontal Bone Loss, Periodontal Atrophy
- Trial name
- NCT07573761
- Where
- Turkey (Türkiye)
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Istanbul Saglik Bilimleri University
Meniere Disease, Osteoporosis
Menier's Disease - Bone Density Study
Meniere's disease is a progressive and debilitating inner ear disease characterised by vertigo and hearing loss. Several studies have linked Menierws disease with lower bone density and lower vitamin D levels.
- Conditions
- Meniere Disease, Osteoporosis, Osteopenia, Vitamin D Deficiency
- Trial name
- NCT05322538
- Testing
- vitamin D plasma levels baseline, Dual-energy X-ray absorptiometry at baseline, cervical Vestibular evoked myogenic potentials at baseline
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- HaEmek Medical Center, Israel
Periodontal Diseases, Periodontal Pocket
Comparison of Gingival Flap Procedure Using Conventional Surgical Loupes vs. Videoscope for Visualization
This study is being performed to compare different methods of visualization during routine gum surgery. The gum surgery is standard of care.
- Conditions
- Periodontal Diseases, Periodontal Pocket, Periodontitis, Periodontal Inflammation
- Trial name
- NCT05932017
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Texas A&M University
Tooth Extraction, Tooth Extraction Site Healing
Assessment of the Impact of Neocement Inject P® (Beta-Tricalcium Phosphate) on Bone Volume in Alveolar Ridge Preservation After Tooth Extraction
The goal of this randomized clinical trial is to assess whether β-TCP (Beta-Tricalcium Phosphate) improves alveolar ridge preservation (ARP) in patients who need tooth extraction.
- Conditions
- Tooth Extraction, Tooth Extraction Site Healing, Alveolar Bone Grafting, Alveolar Bone Loss
- Trial name
- BTCPARPBV (NCT07638319)
- Testing
- Neocement Inject P® (Beta-Tricalcium Phosphate)
- Where
- Portugal
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Egas Moniz - Cooperativa de Ensino Superior, CRL