Clinical trials: Orthodontic Tooth Movement, active
Orthodontics, Root Resorption
Effects of PBM on Fixed-appliance Orthodontic Patients
The aim of this study is to investigate the effects of photobiomodulation therapy (PBM) on the dental and periodontal health of patients undergoing fixed-appliance orthodontic treatment, including orthodontically induced root…
- Trial name
- NCT06199674
- Testing
- photobiomodulation therapy, orthodontic fixed-appliance
- Where
- Hong Kong
- Volunteers
- 50 people
- Sponsor
- The University of Hong Kong
Tooth Wear, Orthodontic Extrusion
Orthodontic and Articular Effects of the One-Step No-Prep Protocol
This study investigates how the One-Step No-Prep protocol with orthodontic assistance affects dental and jaw function in adults treated for localized tooth wear.
- Trial name
- OSNPO (NCT07533240)
- Testing
- Low-dose Cone-Beam Computed Tomography
- Where
- Belgium
- Volunteers
- 30 people
- Sponsor
- Mainjot Amélie
Malocclusion of Anterior Teeth
Clinical Evaluation of Zirconium Dioxide Nano-Coated Arch Wires
"This clinical trial aims to evaluate the clinical performance and efficiency of zirconium dioxide nano-coated orthodontic archwires compared to conventional archwires.
- Trial name
- NCT07813117
- Testing
- Zirconium dioxide nano-coated archwire, Conventional orthodontic archwire
- Volunteers
- 20 people
- Sponsor
- Al-Azhar University
Accelerated Orthodontic Tooth Movement
Comparing MOP, Prostaglandin E1, and Calcitriol to Accelerate Orthodontic Tooth Movement
This study will compare the effects of MOP (micro-osteoperforation), prostaglandin E1, and calcitriol on the rate of orthodontic tooth movement.
- Trial name
- acceleration (NCT07842120)
- Testing
- PGE₁ (pharmacological) • Agent: Prostaglandin E1, Calcitriol (1,25-(OH)₂D₃) local injection • Agent: Calcitriol (1,25-(OH)₂D₃) Vitamin D3, microosteoperforation MOP (surgical)
- Where
- 2 sites in Iraq
- Volunteers
- 60 people
- Sponsor
- Ghufran Dhari Awad
Maxillary Canine Retraction, Local Calcitriol Delivery
Clinical Evaluation of Local Calcitriol Delivery on Maxillary Canine Retraction
This study will evaluate the effect of locally applied Calcitriol on dental and skeletal changes during upper canine retraction.
- Conditions
- Maxillary Canine Retraction, Local Calcitriol Delivery, Orthodontic Tooth Movement
- Trial name
- CALCR25 (NCT07200349)
- Testing
- Calcitriol Delivery
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Crowding of Anterior Mandibular Teeth
Evaluating the Efficacy of Micro-Osteoperforations Technique on the Orthodontic Tooth Movement Acceleration in Moderate Mandibular Anterior Crowding Cases Treated With Clear Aligners
Patients with moderate mandibular anterior crowding will be treated in this study. The efficacy of micro-osteoperforations technique by special drill in accelerating orthodontic tooth movement during clear aligners therapy will…
- Trial name
- NCT05492773
- Testing
- Micro-osteoperforations Technique, Active comparater
- Where
- Syria
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Hama University
Stage IV Periodontitis, Orthodontic Tooth Movement
Effect of MOPs During Orthodontic Movement in Periodontitis Patients
Micro-osteoperforations (MOPs) cause cortical bone injuries and consequently increase the expression of inflammatory mediators, allowing for increased bone and periodontal ligament remodeling associated with orthodontic movement.
- Trial name
- MOPorthoperi (NCT06068270)
- Testing
- Micro-ostoperforations (MOPs)
- Where
- Spain
- Volunteers
- 28 people
- Sponsor
- Universidad Complutense de Madrid
Malocclusion
Comparison of Orthodontic Molar Protraction With and Without Adjunctive Surgery
This study will compare orthodontic molar protraction with and without adjunctive periodontally accelerated osteogenic orthodontic (PAOO) surgery prior to orthodontic tooth movement.
- Trial name
- PAOO (NCT03794726)
- Testing
- Orthodontic Molar Protraction and PAOO, Orthodontic Molar Protraction
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Malocclusion, Canine Retraction
Maxillary Canine Retraction Using Stainless Steel and Titanium-molybdenum Alloy Wires in TAD-supported Segmental Mechanics
The goal of this randomized clinical study is to compare the effectiveness of stainless steel (SS) and titanium-molybdenum alloy (TMA) wires for maxillary canine retraction using TAD-supported segmental mechanics.
- Conditions
- Malocclusion, Canine Retraction, Orthodontics, Tooth Movement Techniques
- Trial name
- NCT07645417
- Testing
- A titanium-molybdenum alloy reverse-closing loop, A stainless steel reverse closing loop
- Where
- Bangladesh
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Tanzila Rafique
Orthodontics
Study of the Use of Orthopulse Photobiomodulation
This PMCF study evaluates the safety and performance of OrthoPulse photobiomodulation to accelerate tooth movement during alignment with fixed appliances.
- Trial name
- NCT05650359
- Testing
- OrthoPulse, No intervention
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Biolux Technology GmbH
Malocclusion of Anterior Teeth
Effects of Laser Therapy and Vitamin D Pills on Braces Tooth Movement: A Random Controlled Study
This clinical trial aims to evaluate the efficacy of low-level laser therapy (LLLT) in conjunction with oral vitamin D3 supplementation in accelerating orthodontic tooth movement in adults with crowded mandibular anterior teeth…
- Trial name
- LLLT (NCT07286474)
- Testing
- Cholecalciferol (Vit D3), Low-Level Laser Therapy, Fixed Orthodontic Appliance
- Where
- Saudi Arabia
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Universiti Sains Malaysia
Angle Class I Malocclusion, Dental Crowding
Clinical Performance of Direct-Printed Versus Thermoformed Aligners
The goal of this study is to evaluate and compare the clinical effectiveness of in-office directly 3D-printed clear aligners versus conventional multilayered thermoformed aligners.
- Conditions
- Angle Class I Malocclusion, Dental Crowding, Tooth Spacing
- Trial name
- NCT07637227
- Testing
- Direct-Printed Aligner, Thermoformed aligner
- Where
- 3 sites in Iraq
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- University of Baghdad
Malocclusion Class I
Diode Laser Versus LED for Maxillary Canine Retraction in Orthodontic Patients
This study aims to compare the effects of diode laser and light-emitting diode (LED) photobiomodulation on maxillary canine retraction during fixed orthodontic treatment.
- Trial name
- NCT07810699
- Testing
- Diode Laser Photobiomodulation, LED Photobiomodulation
- Where
- Vietnam
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Can Tho University of Medicine and Pharmacy
Malocclusion, Clear Aligner Appliance
Impact of Aligner Replacement Protocols on Predictability of Planned Dental Movements: Evaluation of Double Aligner
The study will evaluate the impact of replacing aligners after 7 days with new aligners made of different materials on the predictability of planned dental movements.
- Conditions
- Malocclusion, Clear Aligner Appliance, Orthodontics, Tooth Movement
- Trial name
- NCT06882395
- Testing
- Group 1: FLX aligners for 10 days, Group 3: FLX aligners for 7 days, followed by new FLX aligners for 3 days., Group 2: FLX aligners worn for 7 days, followed by FLX35 aligners for 3 days.
- Where
- Brazil
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- Neodent
Clear Aligner Therapy, Malocclusions
Evaluation of the Effect of Aligner Seaters on the Predictability of Tooth Movement in Clear Aligner Therapy.
The goal of clinical trial is to know the role clear aligner seater. The main question it aims to answer is to evaluate the use of clear aligner seater on the effectiveness of clear aligner therapy by questioning the…
- Trial name
- NCT07726485
- Testing
- Aligner seater
- Where
- Iraq
- Volunteers
- 34 people
- Sponsor
- University of Baghdad
Orthodontic Tooth Movement, Tooth Movement
Evaluation of the Biomechanical Response of Orthodontic Tooth Movement to Clear Aligner vs Fixed Orthodontic Appliance
Abstract Background: Orthodontic tooth movement (OTM) is mediated by biologic responses of the periodontal ligament (PDL) and alveolar bone to applied mechanical forces, involving release of inflammatory mediators such as…
- Trial name
- NCT07399483
- Testing
- diagnostic Test: Collection of GCF: from the gingival sulcus using paper point ,Tooth Mobility via Periotest ,3D Digital Model Superimposition using Intraoral Scanning
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Mansoura University
Tooth Movement Techniques, Distalization by Miniscrews
Evaluation of Three-Dimensional Printed Orthodontic Molar Distalizer
A randomized clinical trial to evaluate a newly designed 3D printed miniscrew-supported molar distalization device in comparison to the conventional miniscrew-supported distal jet appliance in correction of Class II malocclusion…
- Trial name
- RCT (NCT07191158)
- Testing
- Group 1 conventional, Group 2 3D printed
- Where
- Iraq
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- University of Baghdad
Orthodontic Tooth Movement, Low Level Laser Therapy
Comparison of Rate of Tooth Movement Between MOPs vs MOPs & LLLT Combined
Orthodontic treatment is often prolonged, requiring years to achieve desirable outcomes. The prolonged duration of treatment increases the risk of complications such as root resorption, periodontal damage, and patient…
- Conditions
- Orthodontic Tooth Movement, Low Level Laser Therapy, Canine Retraction
- Trial name
- NCT07626580
- Testing
- Micro-osteoperforation, Low Level Laser Therapy and Micro-osteoperforations Combined
- Where
- Pakistan
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Effect of Piezocision and Injectable Platelets Rich Fibrin on Tooth Movement
Evaluation of Piezocision Versus Injectable Platelet-rich Fibrin During Orthodontic Canine Retraction Orthodontic Canine Retraction: A Comparative Clinical Study
Comparison of piezocisin and injectable platelets rich fibrin during canine retraction
- Trial name
- NCT07239024
- Testing
- Iprf and piezocision
- Where
- Egypt
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Malocclusions, Canine Retraction
Assessment of the Locally Administrated Vitamin D3 and Corticision Efficacy on Orthodontic Canine Retraction
To study the effect vitamin D effect on orthodontic tooth movement when used in combination with coticision technique, independent t test or an equivalent non-parametric test will be used for comparison.
- Trial name
- NCT07455656
- Testing
- patients will receive local application of vitamin D3 combined with corticision
- Where
- Egypt
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University