Clinical trials: Oropharyngeal Dysphagia
Oropharyngeal Dysphagia
Utilization of Negative Pressure Suction to Reduce Aspiration in Oropharyngeal Dysphagia
This is an investigator initiated prospective study to determine whether the use of a negative pressure suction in the hypopharynx will reduce the amount of aspiration during Video Fluoroscopic Swallowing Exam (VFSE) among…
- Trial name
- NCT03368079
- Testing
- Negative Pressure Suction Catheter
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- University of California, Davis
Oropharyngeal Dysphagia
Effect of Pharyngeal Inhibition by rTMS on Swallowing Function
The aim of this study is to test the hypothesis that rTMS on the dominant swallowing hemisphere is able to modify swallowing coordination.
- Trial name
- rTMSvideoSS (NCT02170454)
- Testing
- magnetic stimulation
- Where
- France
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University Hospital, Rouen
Brain Stem Infarctions, Dysphagia, Oropharyngeal
Effect of Botulinum Toxin Injection Into Upper Esophageal Sphincter in Patients With Medullary Infarction
Dysphagia is an important complication in patients with medullary infarction, the incidence rate is 57%-69%. Compared with other brain infarctions, the medulla oblongata involves multiple swallowing-related nerve nuclei, and the…
- Conditions
- Brain Stem Infarctions, Dysphagia, Oropharyngeal, Dysphagia, Esophageal
- Trial name
- NCT06196606
- Testing
- Botulinum toxin type A for injection
- Where
- China
- Volunteers
- 20 people
- Sponsor
- The First Affiliated Hospital of Zhengzhou University
Dysphagia
Pharyngocise Dose Response Study
In this study supported by an American Cancer Society grant, the investigators are evaluating two levels of swallowing exercise intensity on the maintenance of swallowing muscles and their function in Head/Neck cancer patients…
- Trial name
- NCT01279837
- Testing
- Pharyngocise
- Where
- United States
- Volunteers
- 130 people
- Sponsor
- University of Florida
Deglutition Disorders, Swallowing Disorder
Validation of BRACS to European Portuguese
The goal of this observational study is to translate and validate the fiberoptic endoscopic evaluation of swallowing scale "The Boston Residue and Clearance Scale - BRACS" to European Portuguese
- Conditions
- Deglutition Disorders, Swallowing Disorder, Dysphagia, Oropharyngeal
- Trial name
- NCT06558435
- Testing
- FEES
- Where
- Portugal
- Volunteers
- 16 people
- Sponsor
- Centro Hospitalar de Entre o Douro e Vouga
Dysphagia, Oropharyngeal, Stroke, Ischemic
Combined Conventional Speech Therapy and Functional Electrical Stimulation in Dysphagia Following Stroke
This study will evaluate the effectiveness of conventional speech therapy associated with functional electrical stimulation in patients with dysphagia after ischemic stroke.
- Trial name
- NCT03649295
- Testing
- Functional Electrical Stimulation, Conventional Speech Therapy
- Where
- Brazil
- Volunteers
- 33 people
- Sponsor
- Hospital Geral de Fortaleza
Oropharynx Cancer, Radiotherapy; Complications
Adaptive RadioTherapy for OroPharynx Cancer
This is a phase II randomized trial, where patients with histologically proven squamous cell carcinoma of oropharynx that have primary tumor (T3 - T4) in place, treated with curative intent chemoradiation, will be randomized to…
- Conditions
- Oropharynx Cancer, Radiotherapy; Complications, Radiotherapy Side Effect, Dysphagia
- Trial name
- ART-OPC (NCT04901234)
- Testing
- Standard radiotherapy +/- chemotherapy, Experimental radiotherapy +/- chemotherapy
- Where
- 2 sites in Australia, Canada
- Volunteers
- 120 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Oropharyngeal Dysphagia
Design and Implementation of a Nutritional Intervention in Patients With Oropharyngeal Dysphagia
The purpose of this trial is to design, implement and evaluate the effect of a nutritional intervention in patients with Oropharyngeal Dysphagia on body composition and oral intake of energy and protein.
- Trial name
- NCT02959450
- Testing
- Modified consistency and volume diet
- Where
- Mexico
- Volunteers
- 127 people
- Sponsor
- Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran
Oropharyngeal Dysphagia, Dysphagia
Subacute Effect of Pharyngeal Pharmacological Sensory Stimulation in Elderly Patients With Oropharyngeal Dysphagia
Oropharyngeal sensory impairments are a potential target for treatment of oropharyngeal dysphagia (OD) in older patients. We previously found acute administration of TRP sensory stimulants improved VFS signs and swallow response.
- Conditions
- Oropharyngeal Dysphagia, Dysphagia, Swallowing Disorder
- Trial name
- FIS2018 (NCT04741620)
- Testing
- Capsaicin 10microM (TRPV1 natural agonist), Piperine 150microM (TRPV1 & TRPA1 natural agonist), Cinnamaldehyde 756,6microM + zinc 70microM (TRPA1 natural agonist)
- Where
- Spain
- Volunteers
- 150 people
- Sponsor
- Hospital de Mataró
Oropharyngeal Dysphagia, Swallowing Disorder
Screening and Intervention of Postextubation Dysphagia
This clinical trial aims to test the validity of a two-item swallowing screen and to examine the effects of the Swallowing and Oral-Care (SOC) Program on resumption of oral intake, incidence of penetration and aspiration, and…
- Conditions
- Oropharyngeal Dysphagia, Swallowing Disorder, Randomized Controlled Trial, Endotracheal Intubation
- Trial name
- NCT03284892
- Testing
- SOC program
- Where
- Taiwan
- Volunteers
- 145 people
- Sponsor
- National Taiwan University Hospital
Acupuncture, Dysphagia
Efficacy and Mechanism of 'Yanjiu Needle' for Pharyngeal Dysphagia Based on sEMG Features
Dysphagia is one of the most common and serious complications following stroke. It can easily lead to aspiration and aspiration pneumonia, reduce patients' quality of life, increase healthcare costs, and result in high mortality…
- Conditions
- Acupuncture, Dysphagia, Surface EMG
- Trial name
- NCT07656025
- Testing
- Yanjiu Acupuncture, a three-point acupuncture technique, control group
- Volunteers
- 100 people
- Sponsor
- The Third People's Hospital of Huizhou
Deglutition Disorders, Stroke
Effect Of Vitalstim In Patients With Chronic Post-stroke Oropharyngeal Dysphagia
Prospective, randomized, controlled, three-arm, open-label, blinded analysis. Patients admitted with stroke diagnosis and with suspected dysphagia that meet the initial inclusion and exclusion criteria will be consented into the…
- Trial name
- VITAL (NCT02379182)
- Testing
- standard clinical care, transcutaneous electrical stimulation at sensory level, transcutaneous electrical stimulation at motor level
- Where
- Spain
- Volunteers
- 90 people
- Sponsor
- Pere Clave
Stroke, Acute, Dysphagia, Oropharyngeal
Feasibility Study of Biofeedback in Dysphagia Therapy Post Stroke
This study will investigate the feasibility of delivering swallowing therapy using surface electromyography as a means of biofeedback to patients with dysphagia in the acute stroke setting.
- Trial name
- NCT03499574
- Testing
- Dysphagia therapy using surface EMG as biofeedback, Usual Care
- Where
- United Kingdom
- Volunteers
- 27 people
- Sponsor
- University of Nottingham
Stroke, Dysphagia
Effect of Kinesiology Taping and Swallowing Exercises on Suprahyoid Muscle Thickness and Swallowing Function in Stroke Patients With Dysphagia
This randomized controlled single-blind study aims to investigate the effect of kinesiology taping combined with resistance exercises on suprahyoid muscle thickness and swallowing function in patients with stroke-related…
- Conditions
- Stroke, Dysphagia, Cerebrovascular Disorders
- Trial name
- NCT06988215
- Testing
- Kinesiology Taping with Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people
- Sponsor
- Istanbul Physical Medicine Rehabilitation Training and Research Hospital
Dysphagia, Head and Neck Cancer
Chemo/XRT +/- Amifostine to Assess Outcomes Related to Xerostomia, Mucositis, & Dysphagia
RATIONALE: Drugs used in chemotherapy work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Radiation therapy uses high-energy x-rays to kill tumor cells.
- Conditions
- Dysphagia, Head and Neck Cancer, Mucositis, Xerostomia
- Trial name
- NCT00503776
- Testing
- exercise intervention, amifostine trihydrate, therapeutic dietary intervention
- Where
- United States
- Volunteers
- 41 people
- Sponsor
- Vanderbilt-Ingram Cancer Center
Dysphagia
Simultaneous Fluoroscopic and Endoscopic Examination of the Oropharyngeal Phase of Deglutition
To correlate findings between two commonly-used types of swallowing studies: videofluoroscopy and flexible endoscopic evaluation of swallowing (FEES).
- Trial name
- NCT00584623
- Where
- United States
- Sponsor
- University of California, Davis
Carcinomas, Squamous Cell, Dysphagia
A Pilot Study of Acupuncture Treatment for Dysphagia
The current standard of care for advanced HNC is concurrent chemoradiation therapy (CRT), which has led to increased survival rates, but with significant acute and long-term toxicities.
- Trial name
- NCT00797732
- Testing
- Acupuncture
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- Dana-Farber Cancer Institute
Otorhinolaryngologic Disease, Otorhinolaryngologic Neoplasm
Ultrasound Evaluation of Tongue Movements in Speech and Swallowing
This study will assess the use of ultrasound-a test that uses sound waves to produce images-as a diagnostic tool for evaluating speech and swallowing.
- Conditions
- Otorhinolaryngologic Disease, Otorhinolaryngologic Neoplasm, Pharyngeal Neoplasm, Polymyositis
- Trial name
- NCT00001167
- Where
- United States
- Volunteers
- 570 people, healthy volunteers welcome
- Sponsor
- National Institutes of Health Clinical Center (CC)
Dysphagia, Oropharyngeal, Stroke
Screening of Dysphagia Via Ultrasonography in Patients With Stroke
Oropharyngeal dysphagia is commonly seen in patients with stroke. Clinical assessment may be used to evaluate dysphagia in patients with stroke however reliability of this method is controversial and videofluoroscopic study is…
- Trial name
- NCT04344392
- Testing
- Ultrasonographic study, Videofluoroscopic study temporal parameters, Videofluoroscopic study distance parameters
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
Dysphagia
The PhINEST Study - Pharyngeal ICU Novel Electrical Stimulation Therapy
This is a prospective, multi-site, randomised, sham-controlled, single-blind (outcome assessor-blinded) study designed to assess the effects of Pharyngeal Electrical Stimulation (PES) (using Phagenyx®) for the treatment of…
- Trial name
- PhINEST (NCT03840395)
- Testing
- Pharyngeal Electrical Stimulation (PES)
- Where
- 5 sites in Austria, Germany and 1 more
- Volunteers
- 72 people
- Sponsor
- Phagenesis Ltd.