Clinical trials: Oral and Maxillofacial Conditions
Pain, Postoperative, Acute Pain
Gabapentin as a Pre-emptive Analgesic in Oral and Maxillofacial Surgical Procedures
The purpose of this study is to assess the effectiveness of pre-operative administration of gabapentin 900 mg in management of acute post-operative pain in patients undergoing oral and maxillofacial surgical procedures.
- Conditions
- Pain, Postoperative, Acute Pain, Facial Pain
- Trial name
- NCT02957097
- Testing
- Gabapentin
- Where
- United States
- Sponsor
- Massachusetts General Hospital
Oroantral Communication
Inverted Periosteal Flap vs Buccal Advancement Flap for Oroantral Communication Closure
This randomized controlled clinical study will evaluate the effectiveness of the inverted buccal periosteal flap in closing recent post-extraction oroantral communications and compare it with the conventional buccal advancement…
- Trial name
- NCT07630701
- Testing
- Inverted Buccal Periosteal Flap, Buccal Advancement Flap
- Where
- Syria
- Volunteers
- 24 people
- Sponsor
- Arab International University
Head and Neck Neoplasms, Quality of Life
Prospective, Observational, Real-world Oral Malignant Tumors Study
The aim of the study is to construct a register system of oral and maxillofacial malignant tumors based on a prospective, observational, real-world study in north Chinese population.
- Conditions
- Head and Neck Neoplasms, Quality of Life, Postoperative Complications
- Trial name
- POROMS (NCT02395367)
- Testing
- resection, adjuvant radiotherapy, neoadjuvant chemotherapy or adjuvant chemotherapy
- Where
- 7 sites in China
- Volunteers
- 30,000 people
- Sponsor
- Beijing Stomatological Hospital, Capital Medical University
Trismus
Evolution of Mouth Opening After Mandibular Block
Trismus is an involuntary contracture of the masticatory muscles, blocking the opening of the jaw, first intermittent then permanent and irreducible.
- Trial name
- OBloc (NCT04961554)
- Testing
- loco-regional anesthesia
- Where
- France
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Surgical Complication, Paresthesia
Trial of Bilateral Sagittal Split Osteotomy Induced Paresthesia Using Ultrasonic vs. Reciprocating Saw Instrumentation
The aim of this prospective study is to analyze the postoperative paresthesias experienced in patients who undergo bilateral sagittal split osteotomies (BSSO) using an ultrasonic saw, versus a reciprocating saw.
- Conditions
- Surgical Complication, Paresthesia, Fracture, Nerve Injury
- Trial name
- NCT05205616
- Testing
- Sonopet ultrasonic saw, Reciprocating saw
- Where
- 2 sites in United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Swelling Lips & Face
Evaluation of Oral and Maxillofacial Swellings by Ultrasonographic Features
Fifty patients were randomly selected with oral and/or maxillofacial swelling, thorough case history and clinical examination were done, then ultrasound examinations were done for all of them and they were classified into five…
- Trial name
- Research (NCT03928730)
- Testing
- resection and removal
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Tarek A Abdelsalam, MD
Oroantral Fistula
A Pedicled Buccal Periosteal Flap for the Closure of Oro-antral Fistula
The aim of this study is to evaluate both clinically and radiologically the efficacy of using the pedicled buccal periosteal flap for closure of oroantral fistula without affecting the original intraoral anatomy.
- Trial name
- NCT05987943
- Testing
- A Pedicled Buccal Periosteal Flap for the Closure of Oro-antral Fistula
- Where
- Egypt
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Marwa Taha Ibrahim
Hemoglobin Level Measurement, Blood Loss During Surgery
Efficacy of Tranexamic Acid Reducing Blood Loss During Maxillofacial Trauma Surgery
Tranexamic acid (TXA) is an inexpensive, easily used and relatively safe drug. It inhibits plasminogen activation and plasmin thus retards clot disintegration.Therapeutic application of tranexamic acid in trauma for preventing…
- Conditions
- Hemoglobin Level Measurement, Blood Loss During Surgery, Duration of Surgery
- Trial name
- NCT07392034
- Testing
- Tranexamic Acid (TXA), Normal saline
- Where
- Pakistan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Nishtar Medical University
TMJ - Oral &Maxillofacial Surgery, Oral and Maxillofacial Conditions
Biologic Augmentation of TMJ Arthroscopy Using BMAC
The goal of this clinical trial is to learn about the efficacy of using Bone Marrow Aspirate Concentrate (BMAC) during temporomandibular joint (TMJ) arthroscopy compared to standard arthroscopic procedures with corticosteroid…
- Conditions
- TMJ - Oral &Maxillofacial Surgery, Oral and Maxillofacial Conditions, TMJ Pain, TMJ Arthralgia
- Trial name
- NCT07536399
- Testing
- Bone Marrow Aspirate Concentrate, Corticosteroid (CS)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Weill Medical College of Cornell University
Pain Control
RCT: Suzetrigine vs Norco for Post-op Pain
Journavx (suzetrigine) is a novel non-opioid analgesic that is FDA approved for acute pain management and may offer a promising alternative for managing postoperative pain.
- Trial name
- NCT07195669
- Testing
- Suzetrigine (SUZ), Norco
- Where
- United States
- Volunteers
- 76 people
- Sponsor
- Jacob Lensing
Nerve Block, Cleft Palate
Maxillary Nerve Blocks in Children - An MRI Study of the Suprazygomatic Approach
Ultrasound-guided suprazygomatic maxillary nerve block (SMNB) will be performed in paediatric patients with or without the aid of ultrasound guidance.
- Conditions
- Nerve Block, Cleft Palate, Analgesia
- Trial name
- NCT05778903
- Testing
- Nerve block
- Where
- Norway
- Volunteers
- 20 people
- Sponsor
- Oslo University Hospital
Temporo-mandibular Dysfunction, Temporomandibular Disorder (TMD)
Temporomandibular Disorder (TMD) Diagnostic Concordance Between Physiotherapist and Surgeon
Jaw disorders is the leading cause in facial pain, affecting many people in the world. Despite many patients finding relief from conservative treatment, many get referred to the surgeon for an evaluation.
- Conditions
- Temporo-mandibular Dysfunction, Temporomandibular Disorder (TMD), Temporomandibular Dysfunction (TMD), Temporomandibular Disorders (TMDs)
- Trial name
- TMD (NCT07560917)
- Testing
- Physiotherapy assessment
- Where
- Canada
- Volunteers
- 70 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Cleft Palate
Comparison of Different Feeding Appliances for Cleft Palate Babies
This study will compare flexible , rigid feeding plates and a special feeding bottle for children with cleft palate.
- Trial name
- NCT06103162
- Testing
- flexible feeding plate
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Tanta University
Cleft Lip, Scarring
Botulinum Toxin to Improve Cosmesis of Primary Cleft Lip Repair
Objective: To determine if the use of botulinum toxin during primary cleft lip repair improves the cosmetic appearance of the cleft lip scar
- Conditions
- Cleft Lip, Scarring, Cleft Palate
- Trial name
- NCT02247193
- Testing
- Botulinum Toxin Type A, Normal Saline Injection
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Inferior Alveolar Nerve Injury, Neurosensory Disturbance
Comparison of the Results of Biostimulation Treatment of Inferior Alveolar Nerve Injury Using Nd:YAG and Diode Lasers With Different Wavelengths.
Intraoral surgical procedures such as sagittal split osteotomy, dental implant placement, and surgical extraction of third molars are widely performed interventions in oral and maxillofacial surgery.
- Conditions
- Inferior Alveolar Nerve Injury, Neurosensory Disturbance, Paresthesia and Hypoesthesia, Nerve Regeneration
- Trial name
- NCT07416006
- Testing
- Nd:YAG Laser Biostimulation, Diode Laser Biostimulation
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Ondokuz Mayıs University
Systemic Inflammatory Response Syndrome (SIRS)
Systemic Inflammatory Response Syndrome (SIRS) in Patients Undergoing Major Procedures in Oral and Maxillofacial Surgery
Patients undergoing major procedures in oral and maxillofacial surgery more often develop a systemic inflammatory response syndrome (SIRS) in the first days of postoperative critical care therapy than patients with a comparable…
- Trial name
- NCT01921049
- Where
- Germany
- Volunteers
- 27 people
- Sponsor
- University of Cologne
Postoperative Complications
Total Intravenous Anesthesia and Inhalation Anesthesia
The aim of us is to define the incidence of postoperative complications and recovery time in view of two anesthesia procedures. During the period between 01.01.2016 and 01.01.2017, totally 583 patients were included in the study…
- Trial name
- NCT03187717
- Volunteers
- 583 people, healthy volunteers welcome
- Sponsor
- Aydin Adnan Menderes University
Prosthesis Failure, Dental, Dental Implant Failed
Customized Oral and Maxillofacial Reconstruction
Regional oral and maxillofacial defects secondary to ablative tissue resection can contribute to severe aesthetic and functional loss, which influences patients' regular life and may cause psychological problems.
- Trial name
- NCT04884126
- Testing
- dental implant placement
- Volunteers
- 150 people
- Sponsor
- KU Leuven
Postoperative Pain
Peripheral Nerve Block Techniques During Cleft Palate
Regional blocks are commonly used in pediatric anesthesia to achieve adequate postoperative analgesia. Suprazygomatic Maxillary nerve block (SMN) and Greater Palatine nerve block (GPN) are regional blocks described for use during…
- Trial name
- NCT04467463
- Testing
- peripheral nerve block by 0.25% levobupivacaine
- Where
- 2 sites in Egypt
- Volunteers
- 40 people
- Sponsor
- Cairo University
Oroantral Fistula, Displaced Tooth
Retrieval of Displaced Root in the Maxillary Sinus Via Lateral Bony Window Using the Piezoelectric Device
Ten patients with displaced root in maxillary sinus will be included in this study. the root will be recieved via lateral bony window in maxillary sinus wall using peizoelectric device then the bony window will be repositioned in…
- Trial name
- NCT06054204
- Testing
- lateral bony window
- Where
- Egypt
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Tanta University