Clinical trials: Oral Surgical Procedures
Periodontal Diseases, Dental Diseases
Instrumentation Effectiveness of Modified, Area-Specific Hand Scalers During Non-Surgical Periodontal Therapy
The goal of this project is to analyze the effectiveness of calculus and biofilm removal using area-specific hand scalers such as Mini Five® Gracey Curettes and Micro Mini Five® Gracey Curettes in periodontal pockets that are 5mm…
- Trial name
- NCT03729167
- Testing
- Scaling and root planing
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Oral Cancer, Oral Cavity Cancer
Radial Forearm Donor Site Closure
The radial forearm free flap (RFFF) is widely used in head and neck reconstruction. Its thinness, pliability, pedicle length, and vessel size are particularly suited for oropharyngeal and oral cavity reconstruction.
- Conditions
- Oral Cancer, Oral Cavity Cancer, Donor Site Complication
- Trial name
- NCT05740033
- Testing
- Split-Thickness Skin Graft for Radial Forearm Donor Site Closure, Hatchet Flap for Radial Forearm Donor Site Closure
- Where
- Canada
- Volunteers
- 120 people
- Sponsor
- University of British Columbia
Periodontitis
Effect of Smoking Cessation on Non-surgical Periodontal Therapy
The aim of this prospective study is to verify the efficacy of smoking cessation on non-surgical periodontal therapy in adult subjects with chronic periodontitis.
- Trial name
- EsCAPE (NCT02493270)
- Testing
- Smoking cessation therapy, Non-surgical periodontal therapy
- Volunteers
- 177 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Periodontitis, Furcation Defects
Use of a Bone Substitute Material in the Surgical Therapy of Furcation Defects
The aim of this randomized clinical trial is to evaluate the potential benefit of the use of a bone substitute material in the treatment of furcation degree II-involved molars.
- Trial name
- NCT06270303
- Testing
- Access flap & surgical debridement, Application of bone substitute material (BioOss Collagen)
- Where
- Sweden
- Volunteers
- 200 people
- Sponsor
- Göteborg University
Periodontitis
The Application of a Fasting- Mimicking Diet in Periodontitis: A Feasibility Study
The aim of the present study is to test if a fasting mimicking diet (FMD) can influence the systemic and periodontal response following non-surgical periodontal therapy.
- Trial name
- NCT05684627
- Testing
- Fast mimicking diet group, Normal diet group
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Akdeniz University
Periodontitis
Minimally Invasive Non- Surgical Periodontal Therapy of Intrabony Defects: Healing Patterns and Smoking Impact
This study is consisted of two arms. At first, a randomized controlled clinical trial will be conducted. Eighty systematically healthy, non-smoker patients with Periodontitis stage III or IV, grades B to C will be included.
- Trial name
- NCT07117097
- Testing
- Minimally Invasive Non- Surgical Periodontal Therapy (MINST), conventional Non-Surgical Periodontal Treatment (cNSPT)
- Volunteers
- 120 people
- Sponsor
- University of Turku
Periimplantitis, Periimplant Diseases
Non-surgical Treatment of Peri-implantitis Using Chitosan Brush and Tetracycline Slurry
Aim: The aim of this prospective, randomized, parallel arm, blind clinical trial is to compare the clinical and radiographic outcomes following non-surgical treatment of mild peri-implant defects using Labrida Bioclean with or…
- Trial name
- NCT06695559
- Testing
- Labrida Bioclean, Tetracycline slurry
- Where
- Greece
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Aristotle University Of Thessaloniki
Post Operative Hemorrhage
Direct Oral Anticoagulants and Management of Blleding Following Dental Extractions. A Prospective Cohort Study.
Evaluation of DOACs treatment on post-extraction bleeding
- Trial name
- DOACS_1 (NCT06365242)
- Where
- Italy
- Volunteers
- 49 people
- Sponsor
- University of Pisa
Polycystic Ovary Syndrome, Periodontitis
Non-surgical Periodontal Therapy and Myo-inositol in Polycystic Ovary Syndrome Women Having Chronic Periodontitis
The Purpose of this study is to assess the correlation between the inflammatory periodontal status and the medical treatment status in Polycystic Ovary Syndrome(PCOS) women with systemic inflammation and to evaluate the effect of…
- Conditions
- Polycystic Ovary Syndrome, Periodontitis, Insulin Resistance
- Trial name
- NCT02633462
- Testing
- scaling and root planing , Myo-inositol, Myo-inositol
- Volunteers
- 56 people
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Periodontal Disease, Periodontitis
Effect of Nano-Hyaluronic Acid in Intrabony Defects Treated With Minimally Invasive Non-Surgical Technique
This randomized controlled clinical trial aims to evaluate the effectiveness of using nano-hyaluronic acid (nano-HyA) gel alongside a minimally invasive non-surgical technique (MINST) to treat deep intrabony defects in patients…
- Trial name
- NCT07595757
- Testing
- Minimally invasive non-surgical technique (MINST), nano-hyaluronic acid
- Where
- Egypt
- Volunteers
- 28 people
- Sponsor
- Cairo University
Periodontitis
Effects of Prebiotic Oral Healthcare Products as an Adjunct to Non-surgical Periodontal Therapy
The aim of this study is to determine the impact of a prebiotic toothpaste and mouthrinse in periodontitis patients as an adjunct to scaling and rootplaning.
- Trial name
- NCT02520375
- Testing
- Prebiotic, Control
- Volunteers
- healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Periodontology, Oral Surgery
Case Series of New Alloplastic Bone Graft Material
A case series to compare the handling and effectiveness of two different treatment approaches using a new alloplastic bone graft material in ridge preservation compared to allograft existing historical data.
- Trial name
- NCT02221557
- Testing
- easy-graft (beta-Tricalcium Phosphate)
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Sunstar Americas
Blepharoptosis, Lagophthalmos
Magnetic Correction of Eye Lid Paralysis
Objective 1: Determine the safety and feasibility of externally mounted magnets for extended management of chronic eyelid movement disorders by measuring visual acuity and corneal and skin integrity and comfort over 8 weeks of…
- Conditions
- Blepharoptosis, Lagophthalmos, Facial Paralysis
- Trial name
- NCT02988856
- Testing
- Magnetic lid system
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Kevin Houston
Chronic Periodontitis
Different Surgical Modalities in the Treatment of Periodontitis
The purpose of the present study is to determine: 1) the efficacy of 2 periodontal surgical procedures, the conservative simplified papilla preservation technique and the more resective open flap debridement with osseous…
- Trial name
- NCT01642641
- Testing
- Non-surgical Subgingival Debridement (SD), Simplified Papilla Preservation Flap, Resective Periodontal Flap with Osseous Recontouring (RPFO)
- Where
- 3 sites in United Kingdom
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Queen Mary University of London
Periodontitis
Effects of PRF and i-PRF on Clinical and Biochemical Parameters in Non-Surgical Periodontal Therapy
The goal of this clinical trial is to learn if adding platelet-rich fibrin (PRF) or injectable platelet-rich fibrin (i-PRF), obtained from the participant's own blood, to standard non-surgical periodontal treatment helps improve…
- Trial name
- PRF-NSPT (NCT07525531)
- Testing
- Non-surgical periodontal therapy (NSPT), Platelet-rich fibrin (PRF), Injectable platelet-rich fibrin (i-PRF)
- Where
- Turkey (Türkiye)
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Ondokuz Mayıs University
Colorectal Cancer, Nutrition Aspect of Cancer
Immunonutrition for Prehabilitation of Patients With Colorectal Cancer Before Surgery
Perioperative immunonutrition has been proposed as a strategy to modulate the inflammatory response and improve outcomes after colorectal surgery.
- Trial name
- IMNUTPREH-CRC (NCT07653737)
- Testing
- Oral nutritional supplement with inmmunonutrition, Standard oral nutritional supplement
- Where
- Spain
- Volunteers
- 56 people
- Sponsor
- Fundacion para la Investigacion Biomedica del Hospital Universitario Ramon y Cajal
Surgical Extraction of Impacted Third Molars
The Use of Manuka Honey to Improve Healing After Third Molars Surgery
Since there is an evidence that Manuka honey is an antibacterial agent, the present study aims to confirm this characteristic and assess its effect in improving healing and reducing postsurgical symptoms, if topically applied…
- Trial name
- NCT02483741
- Testing
- Manuka Honey
- Where
- Syria
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Damascus University
Oral Surgical Procedures, Surgery, Oral
Standardized Osteotomy Guides for Free Flap Reconstruction of Continuous Defects of the Jaws - a Simplified Method
The aim of the present project is to evaluate the outcome from reconstruction of the jaws, with a standardized simplified technique, after a continuous defect.
- Conditions
- Oral Surgical Procedures, Surgery, Oral, Mandibular Reconstruction
- Trial name
- NCT05715359
- Testing
- Reconstruction
- Where
- Sweden
- Volunteers
- 200 people
- Sponsor
- Lund University Hospital
Periodontitis, Mouthwash
Oral Health Outcomes With Amphion Mouthwash as an Adjunct to Non-Surgical Periodontal Therapy
Periodontitis is a chronic inflammation caused by dental plaque that can destroy periodontal tissues. Current primary treatments include mechanical removal methods such as supragingival scaling and subgingival curettage.
- Trial name
- NCT07402694
- Testing
- Amphion® Mouthwash
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Colon Cancer
Mechanical Bowel Preparation and Oral Antibiotics Before Colon Cancer Surgery
This study aims to demonstrate that a preoperative combination of mechanical bowel preparation and oral antibiotics, before elective laparoscopic colon cancer surgery, is associated with a reduction of postoperative surgical site…
- Trial name
- COLONPREP (NCT03475680)
- Testing
- Sennosides colonic preparation, Oral Gentamycin, Oral Ornidazole
- Where
- France
- Volunteers
- 193 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
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