Clinical trials: Oral Malodor (Halitosis)
Halitosis, Gingivitis
Day Long Prevention of Oral Malodor With a Palatal Patch (SmellX) Containing A Herbal Formula
In a previous study the prevention of halitosis by the herbal formula and delivery system (SmellX), were established both in vitro and clinicaly. The duration of relief was established as long as 8 hours.
- Trial name
- SmellX (NCT01388023)
- Testing
- herbal formula for fresh breath
- Where
- Israel
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Halitosis
Oral Hygiene Procedures on Reduction of Oral Malodor
The purpose of the study is to evaluate the effect of various oral hygiene procedures on reduction of oral malodor.
- Trial name
- NCT02113137
- Testing
- group 1: drug: chlorine dioxide, group 2: device: small tooth brush for tongue cleaning
- Where
- Japan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Ei Ei Aung
Oral Malodor, Halitosis
Effect of Miswak and Miswak Extract on Oral Malodor
The aim of this experiment is to investigate the effect of Miswak on oral malodor and to determine whether this effect -if present- is the result of the mechanical action of Miswak or the chemical effect of its extract
- Trial name
- NCT02628938
- Testing
- Miswak extract mouth wash, Miswak stick, Chlorohexidine gluconate
- Where
- Saudi Arabia
- Volunteers
- 212 people, healthy volunteers welcome
- Sponsor
- Riyadh Colleges of Dentistry and Pharmacy
Halitosis
A Clinical Trial to Assess the Effects of a Mouthwash Containing Chlorine Dioxide on Oral Malodor
A mouthwash containing chlorine dioxide would be effective to reduce oral malodor.
- Trial name
- NCT00655772
- Testing
- Chlorine Dioxide
- Where
- Japan
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Tokyo Medical and Dental University
Oral Malodor (Halitosis)
Hydrogen Sulfide Production by Oral Microflora
Oral malodor is a common condition. In most cases this condition results from the proteolytic activity of anaerobic oral bacteria.
- Trial name
- NCT00396539
- Where
- Israel
- Volunteers
- 60 people
- Sponsor
- Hadassah Medical Organization
Halitosis, Oral Malodor
Prevention of Oral Malodor With an Oral Sticker Containing Herbal Formula
the use of a herbal formulation containing sage, echinacea,lavender and mastic gum would prevent oral malodor if delivered in an appropriate delivery system to enable slow release of the active ingredients.
- Conditions
- Halitosis, Oral Malodor, Bad Breath
- Trial name
- NCT00250289
- Testing
- a mucosal sticker with herbal formula
- Where
- Israel
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Oral Malodor (Halitosis), Oral Dryness
Effects of a 50+ Toothpaste on Halitosis and Oral Comfort in Healthy Adults
The goal of this clinical trial is to compare a toothpaste designed for adults aged 50 years and older with a standard toothpaste in orally healthy adults.
- Trial name
- HALI-50PLUS (NCT07780474)
- Testing
- 50+ Toothpaste, Standard Fluoride Toothpaste
- Where
- Italy
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Pavia
Halitosis, Halitoses
Antimicrobial Photodynamic Therapy Or Lingual Scraper Associated With Periodontal Treatment In The Reduction Of Halitosis.
The aim of this study is to compare the effectiveness of two methods of treating bad breath. Patients are enrolled in the study based on an objective test using the Oral Chroma Device, which measures the concentration of volatile…
- Conditions
- Halitosis, Halitoses, Fetor Oris, Oral Malodor
- Trial name
- NCT07433816
- Testing
- Tongue scraper and oral rinse treatment, Tongue scraper and aPDT (photodynamic therapy), full mouth scaling
- Where
- Poland
- Volunteers
- 48 people
- Sponsor
- Medical University of Silesia
Halitosis
Investigating the Effect of Chlorine Dioxide and Chlorhexidine Mouthwash on Bad Breath
The ODOR trial will be a single-centric, double-blinded, parallel-group, double-armed pilot randomized controlled trial with a non-inferiority design.
- Trial name
- NCT06219226
- Testing
- Chlorine dioxide mouthwash, Chlorhexidine mouthwash
- Where
- Hungary
- Volunteers
- 60 people
- Sponsor
- Semmelweis University
Gingivitis, Halitosis
Effect of Mouthwash Containing Camellia Sinensis Extracts on Oral Malodor
The purpose of this study is to determine effect of Mouthwash containing Camellia sinensis extracts on oral malodor and gingival inflammation in gingivitis subjects.
- Trial name
- NCT00932347
- Testing
- Camellia sinensis mouthwash
- Where
- 2 sites in Thailand
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Halitosis
Effect of a Mouthwash Containing Chlorhexidine and Chlorine Dioxide on Halitosis
Halitosis significantly impacts the quality of a patient's life. This randomized, double-blind crossover trial evaluates a mouthwash containing chlorhexidine (0.01%) and chlorine dioxide (0.05%) compared with placebo.
- Trial name
- CHX+CDO (NCT07265102)
- Testing
- CHX 0.01% + CDO 0.05% mouthwash
- Where
- Vietnam
- Volunteers
- 40 people
- Sponsor
- Can Tho University of Medicine and Pharmacy
Halitosis
Effect of an Investigational Lozenge (Biofresh® 4plus) Versus Placebo Control on Oral Malodor (Intra-Oral Halitosis)
This study is designed to evaluate the effect of an investigational lozenge with the enzyme polyphenol oxidase and green coffee extract in reducing and controlling intra-oral halitosis following immediate use and daily use of the…
- Trial name
- NCT05413382
- Testing
- Biofresh® 4plus
- Where
- United States
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Novozymes A/S
Periodontitis, Halitosis
The Additional Effect of Tongue Scraping on Halitosis Parameters in Initial Periodontal Therapy
Periodontitis can lead to tooth loss which may impair chewing ability and aesthetics. In addition, periodontitis can give rise to halitosis.
- Conditions
- Periodontitis, Halitosis, Tongue Condition
- Trial name
- NCT06091228
- Testing
- tongue scraper
- Where
- Belgium
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Periodontal Diseases, Gingivitis
Randomized Trial of a Gum Health Formulation
The purpose of this study is to evaluate the safety and efficacy of a newly formulated foaming gel product on gingivitis and/or moderate periodontitis when used with or without the GLO Science accelerating device (GLO Device)…
- Conditions
- Periodontal Diseases, Gingivitis, Periodontitis, Halitosis
- Trial name
- NCT03196648
- Testing
- Gingival health formulation in an accelerating device, Gingival health formulation on a toothbrush, OTC fluoride toothpaste
- Where
- United States
- Volunteers
- 39 people
- Sponsor
- Glo Science, Inc.
Oral Bacteria, Halitosis
Effect of a Probiotic Water on Oral Health in Adults
The purpose of this study is to evaluate the effects of consuming a probiotic on salivary, plaque, and tongue bacteria, as well as oral malodor (bad breath).
- Trial name
- NCT04473404
- Testing
- Streptococcus salivarius DB-B5 - 2 billion CFU/day, Streptococcus salivarius DB-B5 - 10 billion CFU/day
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Dose Biosystems Inc.
Periodontitis, Olfactory Dysfunction
Olfactory Function and Oral Malodor in Periodontitis Before and After Periodontal Therapy
This prospective cohort study investigated the relationship between oral malodor and olfactory function in adults with generalized periodontitis.
- Conditions
- Periodontitis, Olfactory Dysfunction, Halitosis
- Trial name
- NCT07424300
- Testing
- Scaling and Root Planing (SRP)
- Where
- Turkey (Türkiye)
- Volunteers
- 101 people
- Sponsor
- Batman University
Oral Malodor (Halitosis)
Effect of Toothpastes on Oral Malodor
This study aimed to evaluate the effects of different toothpaste formulations on oral malodor in young adults, addressing the lack of clinical evidence regarding propolis- and probiotic-containing toothpastes, which have…
- Trial name
- NCT07329062
- Testing
- Propolis Containing Toothpaste, Probiotic containing toothpaste, Phosphate-based formulation toothpaste
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Çankırı Karatekin University
Halitosis
Clinical and Microbiological Effects of a Mouthwash Containing Chlorine Dioxide
Previous research has shown the oxidizing properties and microbiological efficacies of chlorine dioxide (ClO2). However, no clinical studies have investigated its microbiological efficacies on periodontal and malodorous bacteria.
- Trial name
- NCT00748943
- Testing
- Chlorine Dioxide
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Tokyo Medical and Dental University
Halitosis
Association Between Dental Implants Properties and Malodor Production
Malodor production is bacterial in origin. The bacterial activity of anaerobic bacteria results in the breakdown of proteins and the production of foul smelling compounds.
- Trial name
- NCT00254839
- Where
- Israel
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Bad Breath
Efficacy of Peppermint and Green Tea in Malodor
Background: Herbal remedies can have the role of prevention and control of bad breath Since in the previous studies, therapeutic and antibacterial effect of green tea and peppermint had been proven .we studied and compared the…
- Trial name
- NCT03053882
- Testing
- mouthwash
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Shahid Beheshti University of Medical Sciences