Clinical trials: Oral Hygiene, open to volunteers
Carious Lesion, Ready-made Crowns
The Relation Between Oral Hygiene and Microbial Load in the Oral Cavity After Restoring Primary Molars With Two Types of Ready-made Crowns
Following the restoration of primary molars with stainless steel and bioflex crowns, an evaluation of the current state of oral hygiene in relation to the amount of microorganisms and gingival health in the oral cavity will be…
- Trial name
- bioflex crown (NCT06767670)
- Testing
- stainless steel crown, bioflex crown
- Where
- 2 sites in Egypt
- Volunteers
- 40 people
- Sponsor
- Al-Azhar University
Dental Plaque and Gingivitis, Oral Hygiene Reinforcement During Fixed Orthodontic Treatment
Mobile Application Push Notification in Improving Oral Hygiene Behaviour in Adolescent Orthodontic Patients
This research looks at whether using a mobile phone app that sends push-notification reminders can help adolescent orthodontic patients keep their teeth and gums cleaner during treatment.
- Trial name
- IMGS_EZGIGI (NCT07288853)
- Testing
- Ezgigi with push notification, EzGigi
- Where
- Malaysia
- Volunteers
- 78 people
- Sponsor
- Kumeran A/L Mohan
Mild Intellectual Disability
Effect of Virtual Reality Distraction on Perceived Pain During Dental Hygiene in Children With Mild Intellectual Disability: A Randomized Controlled Trial
The objective of this study was to evaluate whether the use of a virtual reality (VR) distractor reduces perceived pain during professional oral hygiene sessions in children with mild ID.
- Trial name
- NCT07473479
- Testing
- Professional oral hygiene session, No distractor
- Where
- Italy
- Volunteers
- 102 people
- Sponsor
- Oasi Research Institute-IRCCS
Schizophrenia Disorder
AI-assisted Masticatory Muscle Training in Patients With Schizophrenia
Dysphagia seems to be quite common and potentially severe in schizophrenia, which may lead to acute asphyxia or pneumonia. Dysphagia in schizophrenia could be associated with drug-induced Parkinsonism, dystonia, tardive…
- Trial name
- AI-assisted (NCT07154407)
- Testing
- AI-assisted Mastisting Training App
- Volunteers
- 100 people
- Sponsor
- Kaohsiung Medical University Chung-Ho Memorial Hospital
Gingivitis
Efficacy of an Amine and Zinc Lactate - Containing Mouthrinse in the Home-based Treatment of Plaque-induced Gingivitis in Adolescents.
The goal of this clinical trial is to evaluate if the adjunctive use of an amine and zinc lactate - containing mouthrinse may give significant benefits in the home-based treatment of plaque-induced gingivitis in adolescents.
- Trial name
- SPA (NCT06671106)
- Testing
- toothbrushing, flossing, Toothpaste Product
- Where
- Italy
- Volunteers
- 150 people
- Sponsor
- Università degli Studi di Ferrara
Geriatrics, Oral Health Care
Evaluation of Efficacy of Coconut Oil Mouth Care for Non-autonomous Hospitalised Elderly People.
This is a prospective, longitudinal, randomised, open-label, multicentric, interventional, comparative superiority study. The main objective is to demonstrate the superiority of oral care with coconut oil on the oral status of…
- Trial name
- COCO-CARE (NCT07406425)
- Testing
- Coconut oil mouth care, Glycerin mouthwashes
- Where
- 2 sites in France
- Volunteers
- 94 people
- Sponsor
- University Hospital, Limoges
B Thalassemia Major
Oral Health Status in Children With β-Thalassemia Major
To evaluate the effectiveness of a structured oral health educational program on oral hygiene status and oral health-related quality of life (OHRQoL) among children diagnosed with β-thalassemia.
- Trial name
- NCT07614217
- Testing
- oral health educational program for Immediate Intervention Group, routine oral hygiene instructions
- Volunteers
- 46 people
- Sponsor
- Cairo University
Specific Learning Disabilities, Dental Plaque
Plaque Removal Efficiency in Children With Specific Learning Disabilities
This study aims to evaluate the effectiveness of toothbrushing education on plaque removal in children aged 7-12 years with specific learning disabilities (SLD) and to compare their plaque removal performance with healthy…
- Conditions
- Specific Learning Disabilities, Dental Plaque, Oral Hygiene
- Trial name
- PRE-SLD (NCT07611942)
- Testing
- Standardized Toothbrushing Education
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Alanya Alaaddin Keykubat University
Dental Caries
Caries of First Permanent Molars and Association With Dietary and Oral Habits Among a Group of Egyptian Children
This cross-sectional study aims to assess the prevalence of dental caries in the first permanent molars of Egyptian children aged 6 to 7 years, and to examine how this caries status relates to the children's dietary habits and…
- Trial name
- NCT07725757
- Volunteers
- 272 people, healthy volunteers welcome
- Sponsor
- October University for Modern Sciences and Arts
Oral Health Behavior Change, Oral Hygiene, Oral Health
A Just-in-Time Digital Learning Platform for Teacher Oral Health Training
This randomized controlled trial aims to evaluate the effectiveness and implementation of a Just-in-Time Digital Learning Platform designed to improve teachers' oral health literacy and support the delivery of oral health…
- Conditions
- Oral Health Behavior Change, Oral Hygiene, Oral Health, Digital Literacy
- Trial name
- NCT07645612
- Testing
- Just-in-Time Digital Learning Platform for Teacher Oral Health Training
- Where
- Pakistan
- Volunteers
- 870 people, healthy volunteers welcome
- Sponsor
- Universiti Putra Malaysia
Motivational Interviewing, Periodontitis
Motivational Interviewing and Subgingival Instrumentation Outcomes in Periodontitis
Motivational Interviewing (MI) represents a patient centered counselling approach designed to facilitate behaviour change by guiding patients through the exploration and resolution of ambivalence toward positive health actions.
- Conditions
- Motivational Interviewing, Periodontitis, Oral Hygiene
- Trial name
- NCT07618533
- Testing
- Motivational Interviewing, Oral hygiene instructions
- Where
- India
- Volunteers
- 66 people
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Periodontitis
Performance of the Treatment of Periodontitis According to the Bioperio® Protocol
This multicenter, prospective, single-arm observational study evaluated the clinical performance of the Bioperio® protocol, a standardized, patient-centered framework for managing periodontitis.
- Trial name
- BIOPERIO (NCT07507474)
- Testing
- Periodontal non surgical treatment, Oral Hygiene Instructions, Surgical Periodontal Treatment
- Where
- Italy
- Volunteers
- 5,000 people
- Sponsor
- University of Pisa
Oral Health Behavior Change
SEHAT Virtual Oral Health Promotion for School Adolescents in Pakistan
The goal of this cluster-randomized trial is to learn if the SEHAT program works to improve oral health among school adolescents in Pakistan. It will also assess how the program affects oral health behaviors and knowledge.
- Trial name
- SEHAT (NCT07536958)
- Testing
- SEHAT Virtual Oral Health Education, Conventional Oral Health Education
- Where
- Pakistan
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- Shifa College of Dentistry
Dental Plaque, Bleeding of Subgingival Space
Antibacterial Photodynamic Therapy as an Adjunctive Treatment on Oral Hygiene in Elderly Persons
On average, the dental condition of elderly people is poor due to various reasons. The importance of oral health maintenance of the ageing population has been recognized by the World Health Organization (WHO), as oral health…
- Conditions
- Dental Plaque, Bleeding of Subgingival Space, Oral Complication
- Trial name
- NCT06576063
- Testing
- Lumoral Treatment, Standard oral hygiene methods
- Where
- 3 sites in Finland
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Koite Health Oy
Bacterial Transmission, Intubation Intratracheal
ORAL-PROTECT I: Oral Asepsis Preventing Transmission During Intubation
Postoperative respiratory complications, such as bacterial pneumonia, are common and serious problems after general anesthesia. They can lead to longer hospital stays, more complications, and increased mortality.
- Conditions
- Bacterial Transmission, Intubation Intratracheal, Chlorhexidine
- Trial name
- ORAL-PROTECT I (NCT07669064)
- Testing
- Preoperative oral decontamination with chlorhexidine
- Where
- Germany
- Volunteers
- 60 people
- Sponsor
- University Hospital Ulm
Mechanical Ventilation, Infection Prevention
Oral Care Layered Enhancement for Improved Oral Hygiene in Intensive Care Units
The goal of the ORACLE study is to evaluate the impact of implementing a standardized oral hygiene bundle on outcomes in critically ill, mechanically ventilated patients.
- Conditions
- Mechanical Ventilation, Infection Prevention, Oral Care, Oral Hygiene, Oral Health
- Trial name
- ORACLE (NCT07129733)
- Testing
- Oral hygiene bundle
- Where
- 6 sites in Brazil
- Volunteers
- 4,800 people
- Sponsor
- Hospital do Coracao
Preterm Birth, Low Birth Weight
Periodontal Disease and Small Vulnerable Newborns in Rural Nepal: A Community-based Trial
Periodontal disease in pregnant women has been implicated as a potential risk factor for adverse pregnancy outcomes, including being born preterm, small-for-gestational age, and/or low birth weight.
- Conditions
- Preterm Birth, Low Birth Weight, Small Vulnerable Newborn, Small-for-gestational Age
- Trial name
- NCT07553286
- Testing
- A package of oral health interventions, including a daily antiseptic oral rinse (alcohol-free cetylpyridinium chloride (0.075%))
- Volunteers
- 2,280 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Gingivitis, Healthy Adult
Comparative Evaluation of the Anti-Plaque and Anti-Gingivitis Effects of Nanobiofusion Gingival Gel (NBF), Placebo Gel, and Commercial Toothpaste
The goal of this clinical trial is to learn if Nanibiofusion Gingival Gel (NBF) is able to reduce dental plaque and gum inflammation in adults.
- Trial name
- NCT07850232
- Testing
- Nano Bio-Fusion (NBF) Gingival Gel, Commercial fluoride toothpaste
- Where
- Jordan
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- King Abdullah University Hospital
Hemophilia
Oral Health Status and Oral Health Related Quality of Life in a Group pf Egyptian Hemophilic Children
aim of the study: 1. to assess, investigate, and compare the oral health status and oral health related quality of life of a group of hemophilic Egyptian children before and after an oral health educational program 2.
- Trial name
- NCT07161596
- Testing
- oral health educational program
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Cairo University
Oral Hygiene
Game-based Oral Health Promotion
Parents and caregivers play a key role in shaping children's oral health-related behaviours. However, traditional oral health education (OHE) is not engaging for young children.
- Trial name
- NCT07916896
- Testing
- OHE for children, OHE for parents, OHE interactive game kits
- Volunteers
- 282 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong