Clinical trials: Oral Dysesthesia
Burning Mouth Syndrome
Opiorphin Levels in Fluids of Burning Mouth Syndrome Patients (OPIODYN)
If epidemiological studies indicate relatively low prevalence reported in the general population, idiopathic burning mouth syndrome (BMS) is a common condition among certain groups of the population: 30% of menopausal women…
- Trial name
- OPIODYN (NCT02686359)
- Testing
- sample
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Burning Mouth Syndrome, Burning Mouth
Burning Mouth Syndrome Mouth Guard Prospective Study
This study will seek to test the effectiveness of a nonpharmacologic therapy for burning mouth syndrome (BMS). This nonpharmacologic therapy approach will be the fabrication a protective acrylic mouthguard for the maxillary arch…
- Trial name
- NCT04203134
- Testing
- Mouthguard
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- University of Florida
Oral Lichen Planus, Recurrent Aphthous Stomatitis
Improving Prescribing Quality for Oral Mucosal Disorders Using a Pharmacist-Led Model
This study aims to improve how oral mucosal disorders-such as oral lichen planus, recurrent aphthous stomatitis, burning mouth syndrome, herpes viral infection and oral candidiasis-are treated in dental settings.
- Conditions
- Oral Lichen Planus, Recurrent Aphthous Stomatitis, Burning Mouth Syndrome, Oral Candidiasis
- Trial name
- NCT07721090
- Testing
- Pharmacist-Led Prescribing Optimization and Patient Counselling
- Volunteers
- 336 people
- Sponsor
- University of Fujairah
Burning Mouth Syndrome
Treatment of Burning Mouth Syndrome With Integration of Traditional Chinese Medicine and Western Medicine
This study is an open-label randomized controlled trial of the efficacy of the integration of Traditional Chinese medicine (TCM) and western medicine based on TCM syndrome differentiation.
- Trial name
- NCT04189367
- Testing
- Traditional Chinese Medicine, Western medicine
- Where
- Taiwan
- Volunteers
- 80 people
- Sponsor
- Chang Gung Memorial Hospital
Burning Mouth Syndrome, Quality of Life
Effect to the Photobiomodulation in the Burning Mouth Syndrome
Introduction: Burning mouth syndrome (BMS) is a pathology with a low prevalence, affecting between 0.1% and 3.7% of the general population, the ratio between women and men is between 3 and 7:1.
- Conditions
- Burning Mouth Syndrome, Quality of Life, Anxiety Depression, Dry Mouth
- Trial name
- PBM-BMS (NCT05871580)
- Testing
- Low frequency laser activated photobiomodulation, Low frequency laser photobiomodulation inactive
- Where
- Spain
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Santiago de Compostela
Pain
Assessment of Peripheral GABA Receptors for Local Pain Relief
The effect of peripheral GABAA receptor activation on pain and sensitivity in healthy human subjects has never been investigated.
- Trial name
- NCT02928328
- Testing
- GABA oral solution, Intramuscular GABA, Pain modulation
- Where
- Denmark
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Aalborg University
Burning Mouth Syndrome, Taste Disorder
Burning Mouth Disorder (BMD) - A Neuropathic Pain Disorder
Oral burning can have a multitude of reasons. Recent neurophysiologic study results suggest that a primary burning mouth disorder (BMD) may be a peripheral and/or a central neuropathic disorder.
- Conditions
- Burning Mouth Syndrome, Taste Disorder, Orofacial Pain
- Trial name
- NCT00504387
- Where
- Germany
- Volunteers
- 12 people
- Sponsor
- Markus R. Fussnegger
Burning Mouth Syndrome
Neurogenic Mechanisms in Burning Mouth Syndrome
Burning mouth syndrome (BMS) is characterized by a bilateral burning sensation in the anterior tongue, hard palate and lips in the absence of any clinical or laboratory findings.
- Trial name
- BMS17 (NCT00875537)
- Testing
- Capsaicin oral gel 0.025%, Capsaicin oral gel 0.01%
- Where
- Denmark
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Burning Mouth Syndrome, Stomatodynia
Topical Amitriptyline 1% Gel for the Treatment of Burning Mouth Syndrome
Burning mouth syndrome (BMS) is a chronic oral pain condition that causes a persistent burning or stinging sensation in the mouth, often without visible changes in the tissues.
- Trial name
- TOP-AMI → TOPi (NCT07214181)
- Testing
- Topical amitriptyline 1% gel
- Where
- Spain
- Volunteers
- 30 people
- Sponsor
- Universidad de Murcia
Burning Mouth Syndrome
Therapeutic Options for Treatment of Burning Mouth Syndrome
Burning mouth syndrome is a painful condition of unknown etiology that impairs the quality of life and does not have an adequate therapeutic option.
- Trial name
- NCT04475614
- Testing
- BioGaia Prodentis lozenges, low level laser treatment with Ga-Al-As laser, B vitamin injections (Neurobion, Merck, Darmstadt, Germany)
- Where
- Croatia
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- University of Zagreb
Sleep Disorders, Circadian Rhythm
The Efficacy of Melatonin in the Burning Mouth Syndrome
Burning mouth ( BMS) syndrome is the oral disorder characterized by an intraoral burning sensation for which no medical or dental cause can be found.
- Trial name
- BMS (NCT03788733)
- Testing
- Melatonin 3 mg
- Where
- Spain
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Universidad de Murcia
Burning Mouth Syndrome
Effect of Gluten Free Diet in Patients With Burning Mouth Syndrome
Gluten free diet (GFD) is now being tested in patients affected by schizophrenia, autism and multiple sclerosis, making GFD a possible therapeutic weapon not only for celiac disease or gluten sensitivity.
- Trial name
- NCT01867151
- Testing
- Gluten Free Diet, Normal Diet
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
Burning Mouth Syndrome
Efficacy of Melatonin in Burning Mouth Syndrome (BMS)
The purpose of this study is to determine whether melatonin is effective in the treatment of burning mouth syndrome (BMS).
- Trial name
- BMS2013 (NCT02580734)
- Testing
- melatonin
- Volunteers
- 20 people
- Sponsor
- University of Milan
Pain, Diabetic Neuropathies
A Research Study of V3381 for the Treatment of Diabetic Peripheral Neuropathic Pain
The objective of this study is to investigate the safety and efficacy of an investigational drug, V3381, for the treatment of diabetic peripheral neuropathic (DPN) pain (pain in one's feet and legs, or even in one's hands and…
- Trial name
- NCT00375960
- Testing
- V3381
- Where
- 6 sites in United States, Canada
- Volunteers
- 50 people
- Sponsor
- Vernalis (R&D) Ltd
Burning Mouth Syndrome
Study Evaluating the Laser Diode Effect Burning Mouth Syndrome
The aim of this study was to report the effect of laser diode on the treatment of burning mouth syndrome (BMS) Patients were randomly allocated to two different groups: the first one (group A) underwent Laser diode whereas the…
- Trial name
- laser (NCT02757612)
- Testing
- laser diode
- Where
- Spain
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Universidad de Murcia
Stomatitis, Pain
MucoLock™ for Treatment of Stomatitis
The purpose of this research is to test how well people can tolerate MucoLock™ as a treatment for mouth pain or burning sensation and how well it works to reduce mouth pain or burning sensation.
- Conditions
- Stomatitis, Pain, Burning Mouth, Burning Mouth Syndrome
- Trial name
- NCT07506018
- Testing
- MucoLock Oral Gel
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Baptist Health South Florida
Burning Mouth Syndrome, Glossodynia
Evaluation of the Effectiveness of the Selected Method of Treatment of Primary Burning Mouth Syndrome
The burning mouth syndrome (BMS) is a chronic pain syndrome of the oral mucosa. Feels like experiencing a burning sensation, pain, stinging, or numbness in the mouth along with a feeling of dryness, paraesthesia, taste…
- Trial name
- NCT04884503
- Testing
- Clonazepam tablets, tongue pads
- Where
- Poland
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Wroclaw Medical University
Burning Mouth Syndrome, Orofacial Pain
Burning Mouth Syndrome: Effects of Occlusal Splint Therapy
Burning Mouth Syndrome (BMS) causes chronic oral pain and significantly affects quality of life. Effective treatments are limited and often provide only temporary relief.
- Conditions
- Burning Mouth Syndrome, Orofacial Pain, Mouth Dryness
- Trial name
- NCT07344909
- Testing
- Essix splint
- Where
- Sweden
- Volunteers
- 12 people
- Sponsor
- Malmö University
Fibromyalgia, Irritable Bowel Syndrome
Efficacy of Transcranial Magnetic Stimulation (TMS) in Chronic Idiopathic Pain Disorders
Objectives : To investigate the analgesic effects of repeated sessions of unilateral rTMS in patients with chronic pain syndrome due to fibromyalgia, IBS or burning mouth syndrome. Primary outcome will be numerical pain scores.
- Conditions
- Fibromyalgia, Irritable Bowel Syndrome, Burning Mouth Syndrome
- Trial name
- NCT00374673
- Testing
- Repetitive transcranial magnetic stimulation
- Where
- France
- Volunteers
- 60 people
- Sponsor
- Hospital Ambroise Paré Paris
Primary Burning Mouth Syndrome (BMS)
Theravex® for Burning Mouth Syndrome
In this randomized, double-blind, placebo-controlled trial, 116 adults with primary BMS were assigned (1:1) to receive THERAVEX® Total Oral Care Plus or placebo for 8 weeks.
- Trial name
- NCT07564843
- Testing
- THERAVEX® Total Oral Care Plus
- Where
- Egypt
- Volunteers
- 116 people, healthy volunteers welcome
- Sponsor
- Biointelligent Technology Systems SL