Clinical trials: Opacity
Pulmonary Nodule, Solitary
Is Bronchoscopy Necessary in the Preoperative Workup of GGO Lung Cancer?(ECTOP-1005)
This study is one of Eastern Cooperative Thoracic Oncology Projects (ECTOP-1005). It aims to evaluate the role of flexible bronchoscopy in the pre-operative workup of ground glass opacity featured lung cancer.
- Trial name
- NCT03591445
- Testing
- Flexible Bronchoscopy
- Where
- China
- Volunteers
- 615 people
- Sponsor
- Fudan University
Bone Density Increased, Body Height
Milk Supplementation and Bone Health in Children
Objectives: to examine the effects of a Yili child formula milk and regular milk on bone health and growth in young children. Study design: cluster randomized controlled trial.
- Trial name
- NCT05074836
- Testing
- Formula milk, Regular milk, Control foods
- Where
- China
- Volunteers
- 254 people, healthy volunteers welcome
- Sponsor
- Sun Yat-sen University
Multiple Ground Glass Opacities (GGOs)
A Registry for Patients With Multifocal Ground Glass Opacities (GGOs)
The purpose of this registry study is to actively monitor people with GGOs and collect information about them, so that investigators can learn more about these lesions and about the risk of developing lung cancer in study…
- Trial name
- NCT03802981
- Where
- 32 sites in United States, Canada
- Volunteers
- 338 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Cataract, Lens Opacities
Visual Performance, Patient Satisfaction and PCO Rate After Implantation of a Trifocal Hydrophobic IOL
Prospective, controlled, single-surgeon, single-center post-market clinical follow up study to investigate the clinical outcomes of a hydrophobic trifocal IOL (PhysIOL POD F GF)
- Conditions
- Cataract, Lens Opacities, Presbyopia
- Trial name
- PHY1703 (NCT03306342)
- Testing
- IOL implantation experimental
- Where
- France
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Beaver-Visitec International, Inc.
Segmentectomy
3D Reconstruction in Video-assisted Thoracoscopic Surgery (VATS) Segmentectomy
Anatomical variations of pulmonary vessel may cause serious problems during pulmonary segmentectomy. Three-dimensional （3D）computed tomography (CT) presents 3D images of pulmonary vessels and the tracheobronchial tree and may…
- Trial name
- DRIVATS (NCT04004494)
- Testing
- 3D reconstruction
- Where
- 3 sites in China
- Volunteers
- 191 people
- Sponsor
- Ruijin Hospital
Lung Neoplasms
Safety and Feasibility of Pulmonary Surgery Marker System in the Intraoperative Localization of Small Pulmonary Nodules
As the detection of small pulmonary nodules continuously grows, the intraoperative localization of small pulmonary nodules is in great demand.
- Trial name
- NCT04211051
- Testing
- LungBrella marker implantation and VATS partial lobe resection
- Where
- China
- Volunteers
- 10 people
- Sponsor
- Ruijin Hospital
Floaters, Vitreous Opacities
Imaging of Vitreous Opacities in a Canadian Population
The goal of this clinical trial is to capture imaging data of eye floaters in the population to build an imaging database to learn more about them in.
- Trial name
- NCT06204848
- Testing
- SVO-ID
- Where
- Canada
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- PulseMedica
Corneal Opacities
Corneal Opacities in Children
A prospective observational study on corneal opacities in infants and children (1 month to 18 years old) will be conducted at CHLA. Most of these cases will be due to congenital corneal opacity (e.g.
- Trial name
- OCT (NCT02117323)
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- Oregon Health and Science University
Keratoconus
PRoTECT: Corneal Wavefront Guided PRK + Epi-off CXL vs. PTK+Epi-off CXL in Keratoconus
Keratoconus causes irregular astigmatism and reduced vision. Epi-off corneal crosslinking (CXL) stabilizes the cornea but often leaves higher-order aberrations uncorrected.
- Trial name
- PRoTECT (NCT07372911)
- Testing
- Schwind AMARIS excimer laser, Corneal collagen crosslinking epi-off accelerated
- Where
- Mexico
- Volunteers
- 50 people
- Sponsor
- Instituto de Oftalmología Fundación Conde de Valenciana
Cataract, Lens Opacities
Rotational Stability Analysis of a Toric Monofocal IOL
This is a single-center, prospective PMCF study whereby patients undergoing routine cataract surgery will have monolateral implantation of hydrophilic monofocal toric intraocular lens Ankoris.
- Conditions
- Cataract, Lens Opacities, Astigmatism
- Trial name
- PHY2013 (NCT04933487)
- Testing
- IOL implantation experimental
- Where
- Germany
- Volunteers
- 23 people
- Sponsor
- Beaver-Visitec International, Inc.
Lung Ground-glass Opacities, Active Surveillance
Surveillance for Multifocal GGNs
This study is a single-arm, multi-center, phase III trial conducted under the Eastern Cooperative Thoracic Oncoloy Project (ECTOP) with the identification number ECTOP-1021.
- Trial name
- NCT06097910
- Testing
- Watchful waiting
- Where
- China
- Volunteers
- 370 people
- Sponsor
- Fudan University
Cataract, Lens Opacities
PMCF Study on Monofocal Toric IOL (PODEYE TORIC) in Asia
This is a single-center, prospective, open-label PMCF study whereby patients undergoing routine cataract surgery will have mono- or bilateral implantation of hydrophobic acrylic monofocal toric intraocular lens PODEYE TORIC…
- Conditions
- Cataract, Lens Opacities, Astigmatism
- Trial name
- PHY2102 (NCT04778501)
- Testing
- IOL implantation experimental
- Where
- Philippines
- Volunteers
- 45 people
- Sponsor
- Beaver-Visitec International, Inc.
Pulmonary Nodules, Lung Neoplasms
Deep Learning Time-Series Prediction of Long-Term Growth Patterns of Pulmonary Ground-Glass Nodules Using Serial CT
Pulmonary ground-glass nodules (GGNs) are commonly found on chest CT scans. Some stay stable for years, while others slowly or rapidly turn into lung cancer.
- Conditions
- Pulmonary Nodules, Lung Neoplasms, Adenocarcinoma of Lung
- Trial name
- GGN-Trajectory (NCT07647692)
- Testing
- Serial Thin-Slice Chest CT
- Where
- China
- Volunteers
- 4,750 people
- Sponsor
- Peking University People's Hospital
Multiple Primary Lung Cancers
Treatment of EGFR-TKI for Residual Lesions of Multiple Synchronous Ground-glass Opacities
This study is a multi-center, prospective, double-blind randomized controlled clinical trial. The purpose is to evaluate the efficacy and safety of EGFR-TKI on residual GGOs after surgery in patients with multiple primary lung…
- Trial name
- TERMGGO (NCT04982900)
- Testing
- furmonertinib
- Where
- 6 sites in China
- Volunteers
- 138 people
- Sponsor
- Ruijin Hospital
Cataract, Lens Opacities
PMCF Study on EDOF (Isopure) vs Monofocal (Micropure) IOL
Multicenter, prospective, randomised, controlled, single-blind post-market clinical follow-up (PMCF) study to compare the clinical outcomes of an enhanced depth of focus (EDOF) IOL with the outcomes obtained with a monofocal…
- Trial name
- PHY2001 (NCT04249492)
- Testing
- IOL implantation experimental (Isopure 1.2.3.), IOL implantation active comparator (Micropure 1.2.3.)
- Where
- 12 sites in Austria, Czechia and 4 more
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Beaver-Visitec International, Inc.
Bone Density Increased
Radiographic Assessment of Bone Dimension Around Immediate Implants With FDBA and I-PRF vs FDBA Alone
The present study is a human, prospective, parallel, randomised controlled clinical trial conducted for radiographic assessment of bone dimension around immediate implants with FDBA and I-PRF vs FDBA Alone The trial is in…
- Trial name
- NCT06522321
- Testing
- i-PRF and FDBA
- Where
- India
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Krishnadevaraya College of Dental Sciences & Hospital
Corneal Opacity
Comparison of Ultrasonic Pachymetry With Orbscan in Corneal Haze
This study is planned to compare the results of ultrasonic and Orbscan pachymetry in corneal haze not related to surgery. Corneal haze is graded with slit-lamp by a single examiner.
- Trial name
- NCT00439114
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Baskent University
Eye Diseases, Postcataract Aphakia
Investigation of the Safety and Effectiveness of Monofocal Toric Intraocular Lens (IOL)
This study is a prospective, multicenter, randomized, double masked trial comparing an investigational Monofocal Toric intraocular lens (IOL) (PODEYE TORIC CYL 1.5 D) and a commercially available non-toric monofocal IOL.
- Conditions
- Eye Diseases, Postcataract Aphakia, Cataract, Lens Opacities
- Trial name
- NCT06399211
- Testing
- PODEYE TORIC Monofocal IOL, Alcon AcrySof SA60AT Monofocal IOL
- Volunteers
- 261 people
- Sponsor
- Beaver-Visitec International, Inc.
Cataract, Lens Opacities
Feasibility Investigation of Biometry and Tomography Measurements in a Heterogeneous Patient Cohort
The planned clinical investigation will be conducted to acquire raw data for the development of the algorithm. The data acquisition is intended to obtain first impressions of the potential performance of the changed hardware and…
- Conditions
- Cataract, Lens Opacities, Artificial Lens Implant, Corneal Astigmatism
- Trial name
- BioBase (NCT05458661)
- Testing
- Clinical Prototype BioBase (SN 07 and SN 08)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Carl Zeiss Meditec AG
Lung Cancer, Spreading of Tumor
Impact of ctDNA in Cancer Early Detection and STAS Evaluation in Patients With GGOs
The aim of the study is the early and non-invasive diagnosis of lung cancer in patients with pulmonary ground glass opacity. In particular, objective of the study is to evaluate the presence or absence of circulating tumor DNA…
- Conditions
- Lung Cancer, Spreading of Tumor, Circulating Tumor Cell
- Trial name
- NCT05187767
- Testing
- cf DNA and ct DNA
- Where
- Italy
- Volunteers
- 80 people
- Sponsor
- University of Roma La Sapienza