Clinical trials: Onychomycosis of Toenail
Onychomycosis of Toenail
Photodynamic Therapy For Onychomycosis
The purpose of this study is clinical and mycological clearance of onychomycosis using photodynamic therapy (PDT) with aminolevulinic acid (ALA) 10% gel at 6 months, 3 months, 9 months and 12 months
- Trial name
- NCT07756671
- Testing
- ALA 10% gel, PDT, Urea
- Where
- 3 sites in United States
- Volunteers
- 5 people
- Sponsor
- The University of Texas Health Science Center, Houston
Onychomycosis of Toenail
URGO MICKAEL Filmogel, Topical Treatment of Onychomycosis
The objective of this clinical study is to evaluate the performance of URGO MICKAEL Filmogel as a topical treatment for mild to moderate onychomycosis
- Trial name
- MICKAEL (NCT07828184)
- Testing
- URGO MICKAEL Filmogel
- Where
- France
- Volunteers
- 54 people
- Sponsor
- CEN Biotech
Onychomycosis of Toenail
Safety and Tolerability Study of SKX-16 in Subjects With Moderate to Severe Distal Subungual Onychomycosis
This study is being conducted to determine the pharmacokinetics, systemic exposure, safety and tolerability after daily topical application of SKX-16 (Luliconazole 10% Solution) for duration of 29 days in a maximal use setting in…
- Trial name
- NCT05110638
- Testing
- SKX-16 (Luliconazole 10% Solution)
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- SATO Pharmaceutical Co., Ltd.
Onychomycosis of Toenail
Comparison of Efficacy and Safety Between Methylene Blue-mediated Photodynamic Therapy and 5% Amorolfine Nail Lacquer for Toenail Onychomycosis Treatment
Study centre and address King Chulalongkorn Memorial Hospital Primary objective To compare the efficacy and the safety of methylene blue-mediated photodynamic therapy and 5% amorolfine nail lacquer for toenail onychomycosis in…
- Trial name
- NCT03098342
- Testing
- Methylene blue-mediated photodynamic therapy, Amorolfine 5% Nail Lacquer
- Where
- Thailand
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Chulalongkorn University
Onychomycosis of Toenails, Onychomycosis of Fingernail
Exploring Different Dose-frequency Home Photodynamic Therapy Protocols Using a Novel Home-targeted LED Device for Onychomycosis
This randomized feasibility trial aims to determine the optimal light energy dose and treatment frequency for home-based photodynamic therapy (hPDT) using a novel LED device (L-Home PhoD) for the treatment of onychomycosis.
- Trial name
- HomePDT_Nails (NCT07012343)
- Testing
- Photodynamic Therapy with Conventional Methylene Blue, urea 40% cream
- Where
- Thailand
- Volunteers
- 50 people
- Sponsor
- Chulalongkorn University
Onychomycosis of Toenail
Light Therapy for Onychomycosis Study
This is a pilot prospective study designed to capture information about the safety and effectiveness of the ToeFX Therapy Light.
- Trial name
- NCT05139888
- Testing
- Single wavelength light (red) only, Dual wavelength light (red/blue)
- Where
- Canada
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- ToeFX Inc.
Onychomycosis of Toenail
Safety, Tolerability and Efficacy of Trichostatin A in Patients With Mild to Severe Onychomycosis
This is a multicenter, open label study designed to evaluate the safety, tolerability, and efficacy of topically administered VTR-297 solution.
- Trial name
- NCT07065773
- Testing
- Trichostatin A
- Where
- 5 sites in United States
- Volunteers
- 50 people
- Sponsor
- Vanda Pharmaceuticals
Onychomycosis of Toenail
A Phase 2 Study to Assess the Effectiveness of Topical Terbinafine in Participants With Mild to Moderate Onychomycosis of the Toenails
Onychomycosis is a fungal infection of the toenail caused by a range of organisms, including dermophytes, non-dermophyte molds, and yeasts.
- Trial name
- NCT07382427
- Testing
- 2.4% Topical Terbinafine, 10% Topical Efinaconazole, Vehicle Control
- Volunteers
- 200 people
- Sponsor
- Onyx Axiom
Onychomycosis of Toenail
Effect of the Erchonia® LunulaLaser™ for the Treatment of Toenail Onychomycosis
The purpose of this clinical study is to demonstrate the efficacy of the Erchonia LunulaLaser™, for the treatment of onychomycosis of the toenail.
- Trial name
- NCT06006455
- Testing
- Erchonia LunulaLaser
- Where
- United Kingdom
- Volunteers
- 28 people
- Sponsor
- Erchonia Corporation
Onychomycosis of Toenails
Study in Patients With Onychomycosis Treated With Mycoclear® and Ciclopirox
The goal of this study is to learn about the effectiveness and safety of two products, ciclopirox or Mycoclear®, in treating fungal infections.
- Trial name
- NCT06971341
- Where
- Italy
- Volunteers
- 80 people
- Sponsor
- University of Bologna
Onychomycosis of Toenail
Pilot Study of Swift Microwave Device for Onychomycosis
This is an open, single site, pilot study in Canadian subjects diagnosed with mild to moderate toenail onychomycosis caused by dermatophytes.
- Trial name
- NCT05674747
- Testing
- Swift Microwave treatment - weekly x 4wks, Swift Microwave treatment - Every other week x 4wks, Swift Microwave treatment - Every other week x 24wks
- Where
- Canada
- Volunteers
- 39 people
- Sponsor
- Mediprobe Research Inc.
Dermatologic Disease, Onychomycosis of Toenail
Photodynamic Therapy and Topical Antifungal for Onychomycosis in Patients With Diabetes.
There are different therapeutic alternatives for onychomycosis. Systemic therapy is widely used due to its easy accessibility, low cost and high efficacy, but may be associated with systemic adverse events and drug-drug…
- Conditions
- Dermatologic Disease, Onychomycosis of Toenail, Diabetic Foot, Diabetes Mellitus
- Trial name
- NCT06485050
- Testing
- Photodynamic therapy
- Where
- Spain
- Volunteers
- 10 people
- Sponsor
- Universidad Complutense de Madrid
Onychomycosis of Toenail, Fungal Infection
Topical Application of Essential Oils to Treat Onchomycosis
Patients with documented onychomycosis of one or more toe nails will be treated with a daily application of a topical lacquer containing several essential oils.
- Conditions
- Onychomycosis of Toenail, Fungal Infection, Toenail Infection
- Trial name
- NailFungus (NCT06417983)
- Volunteers
- 50 people
- Sponsor
- Medical Life Care Planners, LLC
Onychomycosis of Toenail
Efficacy and Safety of a Medical Device for the Treatment of Toenail Onychomycosis
This study evaluates the effect of the medical device "Excilor® Forte" in the treatment of toenail onychomycosis. Half of the participants will receive the tested product and the other half will receive a comparator (Amorolfin…
- Trial name
- NCT03382717
- Testing
- Excilor Forte, Loceryl 5%
- Where
- 2 sites in Tunisia
- Volunteers
- 102 people
- Sponsor
- Oystershell NV
Onychomycosis of Toenail
A Study to See if Low Level Laser Light Can Help to Treat Toenail Fungus
The purpose of this study is to determine whether low level laser therapy (LLLT) using the Erchonia LunulaLaser device is effective in clearing toenails with onychomycosis.
- Trial name
- NCT03066336
- Testing
- Erchonia LunulaLaser
- Where
- United States
- Sponsor
- Erchonia Corporation
Onychomycosis of Toenail
To Evaluate Hallux Terbinafine Subungual Gel (HSG) in the Treatment of Onychomycosis
The key objective is to establish the efficacy, safety, tolerability, and pharmacokinetics of investigational drug Hallux Terbinafine Subungual Gel (HSG) administered over 44 weeks to patients with distal-lateral subungual…
- Trial name
- NCT05135910
- Testing
- Hallux Terbinafine Subungual Gel
- Where
- 4 sites in United States
- Volunteers
- 35 people
- Sponsor
- Hallux, Inc.
Onychomycosis of Toenail
Laser Treatment of Toenail Onychomycosis With a 1064 nm Nd:YAG-laser
This study aims to assess if laser treatment can cure fungal infection in toenails. Nail clippings from eligible subjects were obtained and randomised into two groups.
- Trial name
- NCT05260450
- Testing
- 1064 nm Nd:YAG-laser therapy
- Where
- Denmark
- Volunteers
- 20 people
- Sponsor
- Aalborg University Hospital
Toenail Onychomycosis, Distal and Lateral Subungual Toenail Onychomycosis
Blue Light Photodynamic Therapy Treatment for Distal and Lateral Subungual Toenail Onychomycosis
This research study will evaluate the safety and efficacy of using blue light photodynamic therapy (PDT) for treating toenail fungal infections.
- Trial name
- NCT03022903
- Testing
- Aminolevulinic Acid (ALA)
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- University of Alabama at Birmingham
Onychomycosis of Toenail
Clinical Evaluation of Efficacy and Safety of a Medical Device for the Treatment of Toenail Onychomycosis
The efficacy and safety of Solver Pen (prototype number X92001704) is evaluated in this randomized, open label, controlled, investigator-blinded, comparative clinical trial in 76 patients.
- Trial name
- NCT04961684
- Testing
- Solver Pen, Loceryl 5%
- Where
- Tunisia
- Volunteers
- 76 people
- Sponsor
- Oystershell NV
Onychomycosis of Toenail, Onychomycosis
Early Feasibility Study to Evaluate the Efficacy of the RenewalNail™ Plasma Treatment System in Patients With Onychomycosis (Fungal Nail)
A study to determine if a three-treatment protocol with the RenewalNail™ plasma treatment system over a week will result in mycological cure and/or clear nail growth on the treated hallux toe.
- Trial name
- NCT03216200
- Testing
- plasma treatment
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- DeviceFarm, Inc.