Clinical trials: Onychomycosis
Onychomycosis
Clinical Trial on Onychomycosis With P-3058 Nail Solution in Pediatric Population
Pediatric patients affected by mild-to-moderate distal subungual onychomycosis (DSO) or affected by white superficial onychomycosis (WSO), due to dermatophytes, will be treated topically with P-3058 nail solution according to the…
- Trial name
- NCT02547701
- Testing
- P-3058
- Where
- 5 sites in Belgium, Germany and 3 more
- Volunteers
- 20 people
- Sponsor
- Polichem S.A.
Onychomycosis
Comparative Efficacy of Bifonazole Cream vs Placebo After Nail Ablation With Urea Paste
The study is focused to prove that the efficacy of a 1% Bifonazole cream is superior to a placebo cream after non-surgical nail ablation with a 40% urea paste.
- Trial name
- NCT00781820
- Testing
- Bifonazole cream 1%
- Where
- 51 sites in Czechia, Germany and 1 more
- Volunteers
- 693 people
- Sponsor
- Bayer
Onychomycosis
Diode Laser Treatment of Onychomycosis
The purpose of this study is to evaluate the V-Raser diode laser system with investigational Nail Fungus Handpiece in the treatment of onychomycosis.
- Trial name
- NCT01452490
- Testing
- Diode Laser Treatment
- Where
- 2 sites in United States
- Volunteers
- 50 people
- Sponsor
- ConBio, a Cynosure Company
Onychomycosis
Pharmacokinetics and Safety Study of ME1111 in Moderate to Severe Onychomycosis Patients
This study is Randomized, Double-Blind, Vehicle-Controlled, Multiple-Dose Study. The purpose is to determine the safety, tolerability, systemic exposure and pharmacokinetics of ME1111 after repeated daily topical application of…
- Trial name
- NCT01841996
- Testing
- ME1111 solution, Vehicle Solution
- Where
- 2 sites in United States
- Volunteers
- 24 people
- Sponsor
- Meiji Seika Pharma Co., Ltd.
Onychomycosis
A Clinical Investigation on Early Visible Effects of Application of K101 During 8 Weeks on Discoloured and Deformed Nails Resulting From Onychomycosis
The purpose of this study is to further evaluate and document early visible effects on nail appearance of topical K101.
- Trial name
- NCT01180491
- Testing
- K101 nail solution
- Volunteers
- 75 people
- Sponsor
- Moberg Pharma AB
Onychomycosis of Toenail
A Study to See if Low Level Laser Light Can Help to Treat Toenail Fungus
The purpose of this study is to determine whether low level laser therapy (LLLT) using the Erchonia LunulaLaser device is effective in clearing toenails with onychomycosis.
- Trial name
- NCT03066336
- Testing
- Erchonia LunulaLaser
- Where
- United States
- Sponsor
- Erchonia Corporation
Onychomycosis
Randomized, Placebo-Controlled, Double-Blind, Parallel-Group, Multi-Site Phase 2b Clinical Study
A Randomized, Placebo-Controlled, Double-Blind, Parallel-Group, Multi- Site Phase 2b Clinical Study to Assess the Efficacy, Safety and Tolerability of 8-Week Regimens of NVXT topical product in Patients with Mild to Moderate…
- Trial name
- NCT02933879
- Testing
- NVXT topical
- Where
- United States
- Volunteers
- 184 people, healthy volunteers welcome
- Sponsor
- Sun Pharmaceutical Industries, Inc.
Fungal Infection, Onychomycosis
An Open-label Study Evaluating the Effectiveness of CGB-400 Topical Gel for Fungal Infection
The goal of the current study is to evaluate the ability of CGB-400, a proprietary eutectic mixture of GRAS compounds, to clear the toenail fungal growth and improve the appearance of the fungus affected area(s).
- Conditions
- Fungal Infection, Onychomycosis, Tinea Unguium
- Trial name
- NCT05202366
- Testing
- CGB-400 Topical Gel
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- CAGE Bio Inc.
Onychomycosis
A Study of ATB1651 in Adults With Mild to Moderate Onchomycosis
The study is designed to evaluate the Safety, Tolerability and Pharmacokinetics of ATB1651 in participants with mild to moderate onychomycosis
- Trial name
- NCT06327295
- Testing
- ATB1651-102- Cohort 1, ATB1651-102- Cohort 2, ATB1651-102- Cohort 3
- Where
- New Zealand
- Volunteers
- 120 people
- Sponsor
- AmtixBio Co., Ltd.
Diabetes Mellitus, Type 2, Onychomycosis
Laser Treatment for Onychomycosis in Diabetes
Fungal infections of the toe affect one in three people with diabetes. Current treatments for fungal toe infections include oral medications, but these drugs often interact with other common medications.
- Trial name
- NCT02019446
- Testing
- Laser Treatment YAG laser, Standard Treatment (control group) terbinafine hydrochloride tablets
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- BCDiabetes.Ca
Onychomycosis
Treatment of Mild to Moderate Distal Subungual Onychomycosis of the Toenail
The purpose of the study is to determine whether NB002, 0.25%, and 0.5% are safe and effective in the treatment of distal subungual onychomycosis of the toenail.
- Trial name
- NCT00453271
- Testing
- NB-002, Vehicle control
- Where
- 24 sites in United States, Canada
- Volunteers
- 443 people, healthy volunteers welcome
- Sponsor
- NanoBio Corporation
Onychomycosis of Toenails
Efficacy and Safety of AN2690 Topical Solution to Treat Onychomycosis of the Toenail
The purpose of this study is to determine whether AN2690 topical solution is a safe and effective treatment for onychomycosis of the toenail.
- Trial name
- NCT01302119
- Testing
- AN2690 Topical Solution, 5%, Solution Vehicle
- Where
- 32 sites in United States, Canada
- Volunteers
- 604 people
- Sponsor
- Pfizer
Onychomycosis
Bioequivalency Study of Terbinafine Tablets Under Fed Conditions
The objective of this study was the bioequivalence of a Roxane Laboratories' terbinafine tablets, 250 mg, to Lamisil® Tablets, 250 mg (Novartis Pharmaceutical Corporation.) under fed conditions using a single-dose, randomized…
- Trial name
- NCT00602251
- Testing
- Terbinafine
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Roxane Laboratories
Onychomycosis, Tinea Unguium
An Evaluation of the Safety and Pharmacokinetics of Tavaborole Topical Solution for the Treatment of Fungal Disease of the Toenail in Children and Adolescents
This was an open-label study to evaluate the safety and pharmacokinetics of tavaborole 5% topical solution in treating distal subungual onychomycosis (a fungal infection) of the toenail in children and adolescents (ages 6 to 16…
- Trial name
- NCT03405818
- Testing
- Tavaborole 5% Topical Solution
- Where
- 12 sites in United States
- Volunteers
- 55 people
- Sponsor
- Pfizer
Onychomycosis
Efficacy and Safety of Two Treatment Regimens of Topical MOB015 in Adults With Distal Subungual Onychomycosis
Onychomycosis is a fungal infection that affects fingernails and/or toenails. The purpose of this trial is to investigate if MOB015 is effective and safe for treatment of patients with fungal infection of the toenails.
- Trial name
- NCT01246518
- Testing
- MOB015
- Where
- Sweden
- Volunteers
- 250 people
- Sponsor
- Moberg Pharma AB
Diabetes Mellitus, Type 2, Diabetes Mellitus, Type 1
Prevalence and Risk Evaluation of Diabetic Complications of the Foot in A Large Canadian Population
The study aims to assess foot complications among patients with diabetes in Canada, using patient data collected during diabetes foot assessments performed by the LMC Chiropody Team between February 27, 2018 and April 17, 2019.
- Conditions
- Diabetes Mellitus, Type 2, Diabetes Mellitus, Type 1, Foot Deformities, Onychauxis
- Trial name
- PEDAL (NCT04327622)
- Where
- Canada
- Volunteers
- 5,084 people
- Sponsor
- LMC Diabetes & Endocrinology Ltd.
Onychomycosis
Safety and Efficacy of Topical IDP-108 Versus Vehicle in Patients With Onychomycosis
The purpose of this study is to evaluate the safety and efficacy of topical application of IDP-108 versus vehicle in treating patients with onychomycosis.
- Trial name
- NCT01008033
- Testing
- IDP-108, Vehicle
- Where
- 72 sites in United States, Canada and 1 more
- Volunteers
- 870 people
- Sponsor
- Dow Pharmaceutical Sciences
Acquired Hallux Valgus
Prevalence and Clinical Characteristics of the Fungal Nail and Feet Infection in Patients With Hallux Valgus
This study was designed to demonstrate the prevalence of onychomycosis in hallux valgus patients. Additionally, all the prevalence of tinea pedis, the pattern of clinical manifestations, risk factors and coexistence foot…
- Trial name
- NCT02464839
- Where
- Thailand
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Onychomycosis
A Study to Evaluate Efficacy and Safety of Four Posaconazole Regimens With Placebo and Terbinafine in the Treatment of Toenail Onychomycosis (Study P05082AM2)(COMPLETED)
The purpose of this study is to evaluate the efficacy, safety, and tolerability of oral administration of four dosing regimens of posaconazole relative to placebo and terbinafine, in the treatment of toenail onychomycosis.
- Trial name
- NCT00491764
- Testing
- SCH 56592, Terbinafine
- Volunteers
- 218 people
- Sponsor
- Merck Sharp & Dohme LLC
Onychomycosis
Efficacy and Safety Study of 4 Dose Regimens of Oral Albaconazole in Subjects With Distal Subungual Onychomycosis
Phase 2 study to examine how the study drug works and its side effects in subjects with toenail fungus.
- Trial name
- NCT00730405
- Testing
- Albaconazole 100mg, Albaconazole 200mg, Albaconazole 400mg
- Where
- 33 sites in United States, Canada and 1 more
- Volunteers
- 582 people
- Sponsor
- Stiefel, a GSK Company