Clinical trials: One-lung Ventilation
Pulmonary Arterial Hypertension (PAH), Pulmonary Vascular Disease
Assessment of Six-minute Walking Distance 6MWD Between High Altitude HA vs. Sea Level LA in Patients With Pulmonary Arterial Hypertension PAH
To study the effect of relocation from high altitude (Quito: 2850m) to sea level on six-minute walking distance and scores in patients with pulmonary arterial hypertension PAH, who live permanently >2600m.
- Conditions
- Pulmonary Arterial Hypertension (PAH), Pulmonary Vascular Disease, Six-minute Walk Test, High Altitude Effects
- Trial name
- NCT07804472
- Testing
- Descent from 2850m to sea level
- Where
- Switzerland
- Volunteers
- 20 people
- Sponsor
- Silvia Ulrich Somaini
Airway Extubation, Weaning Mechanical Ventilation
One-Hour Positive Pressure Ventilation After a Pressure Support Spontaneous Breathing Trial
This is a randomized, open, multicenter, pragmatic, adaptive clinical trial with intention-to-treat analysis. The study will compare two weaning strategies from mechanical ventilation in critically ill patients admitted to…
- Conditions
- Airway Extubation, Weaning Mechanical Ventilation, Extubation Failure
- Trial name
- NCT07324460
- Testing
- One-hour positive pressure ventilation, Immediate extubation
- Volunteers
- 4,000 people
- Sponsor
- Hospital do Coracao
Thoracic Anesthesia, Geriatric Anesthesia
The Effect of Single Lung Ventilation Duration and Intraoperative Brain Oxygenation on Cognitive Function and Postoperative Pain in Geriatric Patients
One lung ventilation (OLV) is commonly used in thoracic surgery. Although the lack of ventilation of the lung in the surgical area (independent lung) during OLV redirects pulmonary blood flow to the dependent lung, shunt…
- Conditions
- Thoracic Anesthesia, Geriatric Anesthesia, One Lung Ventillation (OLV), POCD - Postoperative Cognitive Dysfunction
- Trial name
- NCT07339124
- Testing
- Cognitive Remediation, Pain Medicine
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Ankara Ataturk Sanatorium Training and Research Hospital
Thoracic Surgery, Epidural Anesthesia
The Effect of Regional Anesthesia Techniques on Brain Tissue Oxygenation in Thoracic Surgery
Today, it is preferred that the lung with pathology for thorax surgery is not under ventilation during operation in terms of reliability and ease of operation.
- Conditions
- Thoracic Surgery, Epidural Anesthesia, Cerebral Oxygen Saturation
- Trial name
- NCT04373174
- Testing
- Regional oximetry probe, Thoracic Epidural block
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Bursa Yuksek Ihtisas Training and Research Hospital
Non Invasive Ventilation Failure in Preterms
Non-invasive Ventilation
Risk factors for non invasive ventilation failure in preterms that lead them to use invasive ventilation
- Trial name
- CPAP (NCT07186790)
- Volunteers
- 160 people
- Sponsor
- Assiut University
Respiratory Failure, Hypoxemia
NIV-FOB, HFNC-FOB- Comparison of Methods
The aim of the study is to asses safety and indications and contraindications for performing bronchofiberocopy (FB) with respiratory support methods, i.e. non-invasive ventilation (NIV) and high flow nasal oxygen therapy (HFNO).
- Conditions
- Respiratory Failure, Hypoxemia, Hypoxemic Respiratory Failure
- Trial name
- NIRA (NCT05655026)
- Testing
- NIV, HFNO
- Where
- Poland
- Volunteers
- 300 people
- Sponsor
- Medical University of Silesia
Pulmonary Neoplasm
Impact of Different Lung Isolation Devices on Pharyngolaryngeal Injuries After Pulmonary Resection
The goal of this clinical trial is to assess the impact of laryngeal mask combined with visual bronchial blocker on pharyngolaryngeal injury after pulmonary resection in patients with pulmonary nodules.
- Trial name
- PLIAP (NCT07117539)
- Testing
- visual bronchial blocker (VBB), double-lumen endotracheal tube (DLT)
- Where
- 3 sites in China
- Volunteers
- 270 people
- Sponsor
- Tingting Li
Thoracic Surgery
A Clinical Comparison of Three Bronchial Blockers for One-Lung Ventilation in Thoracic Surgery
This is a clinical trial comparing surgical conditions during one-lung ventilation with three different bronchial blockers or with double-lumen endobronchial tubes.
- Trial name
- NCT00188916
- Where
- Canada
- Volunteers
- 120 people
- Sponsor
- University Health Network, Toronto
Lung Cancer
Effects of Positive End-Expiratory Pressure on Biventricular Function During One-Lung Ventilation
One lung ventilation (OLV) is essential during thoracic surgery. During OLV, intrapulmonary shunt can be increased resulting hypoxemia. Wang et al measured intrapulmonary shunt by transesophageal echocardiography.
- Trial name
- NCT02483806
- Testing
- PEEP
- Where
- South Korea
- Volunteers
- 36 people
- Sponsor
- Yonsei University
One-Lung Ventilation, Thoracic Surgery
Left Double Lumen Tube Selection
The aim of this study was to determine the accuracy and practicality of ultrasound in the selection of double lumen tube and whether the complications that may occur intraoperatively and postoperatively can be reduced.
- Trial name
- NCT06457763
- Testing
- Ultrasound
- Where
- Turkey (Türkiye)
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Marmara University
Lung Resection Surgery, Anesthesia General
Effect of Oxygen Administration in the Non-dependent Lung on Postoperative Complications After Lung Surgery
The purpose of this study is to analyze the effectiveness of apneic oxygenation and CPAP applied to the non-dependent lung during pulmonary resection surgery in reducing inflammatory response, ischemia-reperfusion injury, and…
- Trial name
- NCT07461779
- Testing
- Medicinal gas - oxygen (Nippon Gases 200 bar), CPAP, Oxygen therapy according to standard clinical practice
- Where
- Spain
- Volunteers
- 177 people
- Sponsor
- Francisco Andres de la Gala
One-Lung Ventilation
Estimating Blood Concentrations of Anaesthetics During One-Lung Ventilation (OLV)
The aims of the study is to determine if end-tidal concentrations of the anaesthetic gases isoflurane and sevoflurane as measured by a standard gas monitor are related to the blood levels during one-lung ventilation.
- Trial name
- NCT02821455
- Testing
- Lung Surgery with One-Lung Ventilation
- Where
- United Kingdom
- Volunteers
- 19 people
- Sponsor
- University of Edinburgh
One Lung Ventilation
Evaluation Of One Lung Ventilation With Ultrasound in Thorax Surgery Operations
BACKGROUND: The aim of this study is to evaluate the confirmation of double lumen tube placement with thoracic Ultrasound (USG) in thorax surgery operations with one lung ventilation.
- Trial name
- NCT06064773
- Testing
- thoracic USG
- Where
- Turkey (Türkiye)
- Volunteers
- 130 people
- Sponsor
- Dokuz Eylul University
Ventilator Lung, Anesthesia; Functional
Minimal Flow Application in One Lung Ventilation
Interest in low fresh gas flow anesthesia has increased in recent years. The high standard of anesthesia machines, the presence of monitors that continuously and thoroughly analyze the anesthetic gas composition, and the…
- Trial name
- NCT04376307
- Testing
- minimal flow anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Dr. Lutfi Kirdar Kartal Training and Research Hospital
Pleural Effusion, Malignant, Pleural Mesothelioma
A Comparative Study Between Regional Anesthesia in Thoracoscopes and the Conventional General Anesthesia
Video-assisted thoracic surgery (VATS) is usually performed with general anesthesia and single lung ventilation. However, performing thoracic surgery under awake regional anesthesia has several potential advantages including…
- Conditions
- Pleural Effusion, Malignant, Pleural Mesothelioma, Pleural Empyema, Pulmonary Diseases or Conditions
- Trial name
- VATS (NCT05077111)
- Testing
- Thoracic Epidural Anesthesia, General Anesthesia with One Lung Ventilation
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Mohamed Reda Ashour
Thoracic Surgery, One Lung Ventilation
Insertion Depth of Left-sided Double-lumen Tube: a New Predictive Formula
The authors developed a formula for predicting the accurate depth of DLT insertion into the appropriate bronchus based on height as follows [The predicted insertion depth of left DLT (cm) equals 0.249 × (BH)0.916] [R].
- Conditions
- Thoracic Surgery, One Lung Ventilation, Left-sided Double Lumen Tube
- Trial name
- NCT04329416
- Testing
- Predicted depth of insertion, Optimized depth of insertion, Adjustment of depth of insertion
- Where
- Saudi Arabia
- Volunteers
- 65 people
- Sponsor
- Imam Abdulrahman Bin Faisal University
Positive-Pressure Respiration, Intrinsic
Flow Controlled Ventilation in Thoracic Surgery
This trial investigates effects of individualized (by compliance guided pressure settings) flow-controlled ventilation compared to best clinical practice pressure-controlled ventilation in thoracic surgery requiring one lung…
- Trial name
- NCT04534933
- Testing
- Evone, Primus
- Where
- Austria
- Volunteers
- 46 people
- Sponsor
- Medical University Innsbruck
Thoracic Surgery, Low-flow Anesthesia
Effect of Low-Flow Anesthesia in Single Lung Ventilation on Postoperative Respiratory Complications
Mechanical ventilation in thoracic surgery patients is often complicated because patients are usually in the lateral decubitus position and the operated lung is intermittently deflated to facilitate surgical exposure .
- Trial name
- Low-Flow Anest (NCT06838091)
- Testing
- Observational
- Where
- Turkey (Türkiye)
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Başakşehir Çam & Sakura City Hospital
Patients Are Recruited From One Thoracic and Cardiac Surgery ICU
Study of Safety and Efficacy on Neuromyopathy of Early Standing With the Assistance of Tilt Table in Critically Patients
Critically ill patients frequently develop muscle weakness due to critical illness-related acute neuropathy and/or myopathy. This disorder is associated with difficulties in weaning from mechanical ventilation, prolonged…
- Trial name
- TILT (NCT02047617)
- Testing
- the standard physiotherapy group, standing table group
- Where
- France
- Volunteers
- 145 people
- Sponsor
- Centre Chirurgical Marie Lannelongue
Lung Neoplasms
Hemodynamic Changes During One Lung Ventilation in Non-intubated Vedio-assisted Thoracoscopic Operations
Non-intubated thoracoscopic surgery has been proved as an adequate alternative for management of many lung conditions such as pneumothorax , lung volume reduction, pulmonary metastasectomy, removal of lung nodules, segmentectomy…
- Trial name
- NCT02123173
- Where
- Taiwan
- Volunteers
- 71 people
- Sponsor
- National Taiwan University Hospital