Clinical trials: One-Lung Ventilation
One Lung Ventilation, Continuous Positive Airway Pressure
Differential Lung Ventilation vs. CPAP
In this study we compared the efficacy of continuous positive airway pressure (CPAP) to differential lung ventilation, in terms of patient's oxygenation, during video assisted thoracoscopic lung resection.
- Conditions
- One Lung Ventilation, Continuous Positive Airway Pressure, Differential Lung Ventilation
- Trial name
- NCT03563612
- Testing
- cpap
- Where
- Israel
- Volunteers
- 29 people
- Sponsor
- Rambam Health Care Campus
Thoracic Surgery
Pressure-Controlled vs Volume-Controlled Ventilation During One Lung Ventilation
Compared with the information available in sepsis and trauma-associated ARDS, less is known about the cause and pattern of lung injury after thoracic surgery. Definition of lung injury in this context is difficult.
- Trial name
- NCT00975468
- Testing
- Pressure Controlled vs. Volume Controlled Ventilation during OLV
- Where
- Saudi Arabia
- Volunteers
- 40 people
- Sponsor
- King Faisal University
Lung Cancer
Effects of Intraoperative Continuous Airway Pressure (CPAP) on the Inflammatory Response to One-lung Ventilation
This is a randomized placebo-controlled trial studying the effects of intraoperative continuous airway pressure (CPAP) on the inflammatory response of the lung with cancer undergoing lobectomy.
- Trial name
- NCT01368601
- Testing
- CPAP (Continuous airway pressure)
- Where
- Spain
- Volunteers
- 60 people
- Sponsor
- Parc de Salut Mar
Mechanical Ventilation Complication
Effect of Anesthetics on Oxygenation and Microcirculation During One-lung Ventilation
One-lung ventilation during thoracic surgery may affect systemic oxygenation and peripheral microcirculation by hypoxic pulmonary vasoconstriction.
- Trial name
- NCT02191371
- Testing
- propofol, desflurane
- Where
- South Korea
- Volunteers
- 104 people
- Sponsor
- Seoul National University Hospital
Lung Cancer, Lung Diseases
Comparison of Double Lumen Tube Location Verification Techniques in Single Lung Ventilation
The aim of this study was to compare auscultation, fiberoptic bronchoscopy (FOB) and video double lumen tube (VDLT) double lumen tube (DLT) location confirmation techniques in terms of intraoperative tube location confirmation…
- Trial name
- NCT07107893
- Testing
- double lumen tube with video
- Where
- Turkey (Türkiye)
- Volunteers
- 93 people
- Sponsor
- Kayseri City Hospital
Pulmonary Arterial Hypertension (PAH), Pulmonary Vascular Disease
Assessment of Total Pulmonary Resistance sPAP/CO Between Sea Level LA vs. High Altitude HA After Re-ascent in Patients With Pulmonary Arterial Hypertension PAH
To study the effect of a re-ascent after a one-week stay at sea level (after prior descent from 2850m) to high altitude (Quito Ecuador: 2850m) on pulmonary resistance (sPAP/CO) and other hemodynamic outcomes in patients with…
- Conditions
- Pulmonary Arterial Hypertension (PAH), Pulmonary Vascular Disease, High Altitude, Echocardiography
- Trial name
- NCT07804693
- Testing
- Re-Ascent from sea level to 2850m
- Where
- Switzerland
- Volunteers
- 20 people
- Sponsor
- Silvia Ulrich Somaini
One Lung Ventilation in Thoracic Surgery
Comparison of Double-lumen Tube Intubation Between Fiberoptic Bronchoscopy and Video Laryngoscope
The goal of this clinical trial is to compare the first-attempt success rate in double-lumen tube intubation. The main question it aims to answer: Is there any difference in the first-attempt success rate of intubation between…
- Trial name
- NCT07241208
- Testing
- Fibertoptic Bronchoscopy
- Where
- South Korea
- Volunteers
- 130 people
- Sponsor
- Kyung Hee University Hospital at Gangdong
Heart Valvular Disease, Coronary Arteriosclerosis
Comparison of Airway Management With Bronchial Blocker and Double-Lumen Tube in Single-Lung Ventilation
In this study, the primary aim is to compare the impact of using a double-lumen tube and bronchial blocker for single-lung ventilation in patients undergoing minimal invasive cardiac surgeries on postoperative pulmonary…
- Conditions
- Heart Valvular Disease, Coronary Arteriosclerosis, One-lung Ventilation
- Trial name
- NCT06299735
- Testing
- Minimally Invasive Cardiac Surgery (airway management with double-lumen tube), Minimally Invasive Cardiac Surgery (airway management with endobronchial blocker)
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Ankara City Hospital Bilkent
Acute Respiratory Distress Syndrome
Very Low Tidal Volume vs Conventional Ventilatory Strategy for One-lung Ventilation in Thoracic Anesthesia
The purpose of this study is to determine if a protective ventilatory strategy during one-lung ventilation (OLV) based on low tidal volume, PEEP and alveolar recruitment maneuver can reduce Acute Respiratory Distress Syndrome…
- Trial name
- NCT01504893
- Testing
- Protective one lung ventilation
- Where
- 16 sites in Italy
- Volunteers
- 984 people
- Sponsor
- Azienda Ospedaliera S. Maria della Misericordia
Pulmonary Embolism, Sleep Apnea Syndrome (OSAS)
Impact of Sleep Related Breathing Disorders on Outcomes of Acute Pulmonary Embolism
This study aimsto compare short-termclinical outcomesand one-year recurrence rates in patients with acute pulmonary embolism with versus without sleep-disordered breathing, recruited from Alexandria MainUniversityHospital.
- Trial name
- NCT07356908
- Testing
- polysomnography
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Alexandria University
Neonatal Respiratory Distress Syndrome
Early Neonatal Respiratory Distress: Changes in Level IIb Hospital Over a Period of One Year
Respiratory distress is one of the first hospital grounds during the neonatal period. The clinical presentation and severity vary by gestational age and cause.
- Trial name
- DROPE (NCT02824497)
- Testing
- No intervention. It's a description study
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Fondation Hôpital Saint-Joseph
Postoperative Pulmonary Complications, One Lung Ventilation
The Effect of Single Lung Ventilation Duration on Postoperative Pulmonary Complications in Thoracic Surgery
This observational study investigates the relationship between the duration of single-lung ventilation (SLV) and the incidence of postoperative pulmonary complications (PPCs) such as pneumonia, pneumothorax, hemothorax, acute…
- Conditions
- Postoperative Pulmonary Complications, One Lung Ventilation, Ards, Postoperative Pulmonary Atelectasis
- Trial name
- NCT07100860
- Testing
- One-Lung ventilation
- Where
- Turkey (Türkiye)
- Volunteers
- 134 people
- Sponsor
- Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital
Thoracic Surgery, Lung Isolation
A Clinical Comparison of Two New Bronchial Blockers vs. Double Lumen Tubes in One Lung Ventilation
Patients undergoing thoracic surgery require selective ventilation of one lung, which allows surgery to proceed on the operative lung that is deflated, and no longer moving.
- Trial name
- NCT02983149
- Testing
- Double lumen tube, Fuji blocker, EZ blocker
- Where
- Canada
- Volunteers
- 90 people
- Sponsor
- University Health Network, Toronto
Pulmonary Disease
Effect of Different Oxygen Concentration on Postoperative Pulmonary Complications After Pulmonary Reexpansion
To evaluate the effect of 80% inspiratory oxygen fraction (FiO2) and 30% FiO2 on the incidence of pulmonary complications after pulmonary reexpansion following one-lung ventilation and 2-hour postoperative within the first 7 days…
- Trial name
- NCT06202586
- Testing
- low FiO2, high FiO2
- Where
- China
- Volunteers
- 300 people
- Sponsor
- RenJi Hospital
One-Lung Ventilation, Thoracic Surgery Video Assisted
The Effects of Different Types of Non-ventilated Lung Management on DO2 During OLV in the Supine Position
The aim of this study is the comparison of oxygen delivery during OLV+capnothorax and OLV+capnothorax and CPAP.
- Conditions
- One-Lung Ventilation, Thoracic Surgery Video Assisted, Supine Position
- Trial name
- OLVinFACHIR (NCT02959515)
- Testing
- Capnothorax, Capnothorax and CPAP
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- Centro Cardiologico Monzino
Pulmonary Complication, Thoracic Surgery
Driving Pressure Limited Ventilation During Video-assisted Thoracoscopic Lobectomy
This study aims to investigate the feasibility of a driving pressure limited mechanical ventilation strategy compared to a conventional strategy in patients undergoing one-lung ventilation during Video-assisted thoracoscopic…
- Trial name
- NCT03177564
- Testing
- Protective ventilation 1, Protective ventilation 2, Driving Pressure Limited Ventilation
- Where
- China
- Volunteers
- 90 people
- Sponsor
- The Affiliated Hospital of Xuzhou Medical University
Obese Patients, One Lung Ventilation
Effects of 1:1 Inspiratory to Expiratory Ratios on Oxygenation and Intrapulmonary Shunt Fraction During One Lung Ventilation in the Obese Patients
One-lung ventilation, even in patients with healthy weight, causes an impairment in gas-exchange and respiratory mechanics. We hypothesized that oxygenation during the one-lung ventilation in obese patients would be improved by…
- Trial name
- NCT02185378
- Testing
- I:E ratio 1:2, I:E ratio 1:1
- Where
- South Korea
- Volunteers
- 36 people
- Sponsor
- Yonsei University
Epidural Block, Electrical Impedance Tomography
Epidural Block Impairs HPV During One-lung Ventilation: an EIT- Based Prospective Observation Study
Define the effect of epidural block on HPV by EIT.
- Trial name
- NCT04730089
- Testing
- Electrical impedance tomography
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Shanghai Zhongshan Hospital
Prone Positioning, Covid19
Use of Combined Prone Positioning and High-Flow Nasal Cannula, and Non-invasive Positive Pressure Ventilation to Prevent Intubation in COVID-19 Infection
This research aims to understand if prone positioning combined with high-flow nasal cannula (HFNC) or non-invasive positive pressure ventilation (NIPPV) safely reduce the rate of intubation in acute hypoxemic and/or hypercapnic…
- Conditions
- Prone Positioning, Covid19, Hypoxemic Respiratory Failure, ARDS
- Trial name
- NCT04694638
- Testing
- Body position change
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Mayo Clinic
One-Lung Ventilation
Estimating Blood Concentrations of Anaesthetics During One-Lung Ventilation (OLV)
The aims of the study is to determine if end-tidal concentrations of the anaesthetic gases isoflurane and sevoflurane as measured by a standard gas monitor are related to the blood levels during one-lung ventilation.
- Trial name
- NCT02821455
- Testing
- Lung Surgery with One-Lung Ventilation
- Where
- United Kingdom
- Volunteers
- 19 people
- Sponsor
- University of Edinburgh