Clinical trials: Older People
Frailty
Psychometric Properties of the Elderly Health Questionnaire Among Community-dwelling Older People
The aims of this study are to validate the reliability and validity of Elderly Health Questionnaire in assessing frailty risk of community-dwelling older adults.
- Trial name
- NCT04166123
- Where
- Taiwan
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Fall Prevention, Exercise
Comparison of a Group-delivered vs. Individually Delivered 'LiFE' Program
In the Lifestyle-Integrated Functional Exercise (LiFE) program, exercises to increase strength and improve balance are embedded into daily life activities.
- Trial name
- LiFE-is-LiFE (NCT03462654)
- Testing
- iLiFE, gLiFE
- Where
- 2 sites in Germany
- Volunteers
- 310 people, healthy volunteers welcome
- Sponsor
- Heidelberg University
Healthy Aging, Elderly (People Aged 65 or More)
Sandplay-Act. Older: Structured Sandplay Activity for Older Individuals
This research was planned to determine the effect of structured sandplay activities on positive and negative affect and levels of meaning in life in elderly individuals.
- Trial name
- NCT07735351
- Testing
- Sandplay-Act. Older: Structured Sandplay Activity for Older Individuals, Control
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Suleyman Demirel University
Immunosenescence, Uninfected Older
Interferon Reference for Older People - REFIPA Study
The diagnosis of respiratory viral infections is mainly based on PCR tests targeting the DNA or RNA of suspected viruses, including SARS-CoV-2, RSV and influenza viruses.
- Trial name
- REFIPA (NCT07239830)
- Testing
- Uninfected older adults
- Where
- France
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Older Persons Interested in Improving Their Brain Health
A Comparison of Two Approaches to Developing Brain Health Programs
This is a research study, designed to test and create new ideas that other people can use. The purpose of this research study is to evaluate two ways of helping people learn to keep their brain healthy.
- Trial name
- NCT04822129
- Testing
- Treatment as Usual, Cogtrastim Model
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Nova Southeastern University
Healthy, Aging
Homeostatic Sleep Regulation in Older Persons
The purpose of this study is to test the hypothesis that sleep homeostasis, also known as sleep pressure or sleep drive, is different in healthy older and younger individuals.
- Trial name
- NCT00601445
- Testing
- Amount of sleep and wake
- Where
- United States
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- National Institute on Aging (NIA)
Old Age; Debility
Older People Gait: Physiomechanics and Functionality
The aim of study is to investigate gait in active elderly people regarding the kinematic parameters of gait, indicators of physical fitness and quality of life.
- Trial name
- NCT04348539
- Testing
- Balance training
- Where
- Brazil
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Federal University of Rio Grande do Sul
Sarcopenia
Cut-off Values of Muscle Thickness Ratio for Sarcopenia
The loss of muscle mass is one of the major diagnostic criteria for sarcopenia. Many methods are also used for the definition of sarcopenia. However there is no information about cut-off values in this respect in the literature.
- Trial name
- NCT03993405
- Testing
- Ultrasonographic evaluation
- Where
- Turkey (Türkiye)
- Volunteers
- 292 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Healthy Ageing
Efficacy of a Toe Flexion Training Protocol on Older Adults' Mobility
This randomized controlled trial aims to explore the effect of a toe flexion resistance training protocol on toe flexion strength and morphology, as well as in older adults (65-85 completed years) mobility related construct.
- Trial name
- PRP-Pied-AUT (NCT05703945)
- Testing
- Progressive training program, Control group
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Major Depressive Episode (MDE), Beliefs
Belief Update: The Effects of Depression and Antidepressants in Older People
People in good health do not perceive the future in the same way as those suffering from depression. This difference in perception affects behaviour and emotions and warrants further investigation, both before and after treatment…
- Conditions
- Major Depressive Episode (MDE), Beliefs, Beliefs About Future, Depression
- Trial name
- OLDBELIEFS (NCT07681492)
- Testing
- Response to questionnaire
- Where
- 2 sites in France
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Hospital Center Guillaume Régnier
COVID-19
A Clinical Trial to Evaluate the Recombinant SARS-CoV-2 Vaccine (CHO Cell) for COVID-19
phase I study will evaluate safety and immunogenicity of a recombinant SARS-CoV-2 vaccine (CHO cell) in Chinese healthy population aged 3 years and older.
- Trial name
- NCT04869592
- Testing
- low-dose Recombinant SARS-CoV-2 Vaccine (CHO cell), high-dose Recombinant SARS-CoV-2 Vaccine (CHO cell)
- Where
- China
- Volunteers
- 3,100 people, healthy volunteers welcome
- Sponsor
- National Vaccine and Serum Institute, China
Aging, Fall
Design and Implementation of a Physical Exercise Program With Virtual Reality to Improve Functional Capacities in Older People.
TITLE: Desing and implementation of a Immersive Virtual Reality exercise program to improve balance in older people INTRO: Older people grow around the world at a faster rate than any other age group, resulting in an accelerated…
- Conditions
- Aging, Fall, Quality of Life
- Trial name
- NCT04336670
- Testing
- Immersive Virtual Reality exercise program, Usual care
- Where
- Spain
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Pablo Campo-Prieto
Sarcopenia in Elderly
The Effect of Adding Elastic Resistance Training in Routine Physical Exercise on Walking Speed of Elderly People With Sarcopenia in Griya Wreda Jambangan, Surabaya
The goal of this randomized clinical trial is to learn whether adding elastic resistance training (ERT) to routine physical exercise can improve walking speed in older adults aged 60 years or older with sarcopenia living at Griya…
- Trial name
- NCT07859969
- Testing
- Elastic Resistance Training, Routine Physical Exercise
- Where
- Indonesia
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Dr. Soetomo General Hospital
Health Services, Geriatric
Self Care for Older Persons in Singapore: An Intervention Study
The main aim of the project is to evaluate a self-care intervention program aimed at enhancing the ability of mildly disabled and healthy older persons in Singapore to manage their health.
- Trial name
- SCOPE (NCT01672177)
- Testing
- Chronic disease self-management training
- Where
- 12 sites in Singapore
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- National University of Singapore
Cognitive Change
Yoga Training and Retinal Vasculature
This study will compare the impact of a novel high-speed, cued yoga program to a standard yoga program on retinal microvasculature, cognition and neuromuscular function.
- Trial name
- NCT06099405
- Testing
- High-speed, Cognitive Challenge Yoga, Traditional yoga
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- University of Miami
COVID-19, Vaccine Reaction
Improving Vaccination in Older Adults by Inducing Autophagy With Spermidine
Easing the morbidity and economic burden of age-related diseases is one of the major medical challenges. One of the key obstacles to healthy ageing is immune senescence, including the failure of lymphocytes to respond adequately…
- Trial name
- NCT05421546
- Where
- United Kingdom
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Oxford
Aging, Hiv
2nd AC+: New Village Model
This study evaluates implementation of the Village Model to support older people living with HIV.
- Conditions
- Aging, Hiv, Loneliness, Social Isolation
- Trial name
- 2nd AC+ (NCT04323176)
- Testing
- Village Model implementation
- Where
- 2 sites in United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Muscle Weakness, Bone Health
Healthy Older People Everyday (HOPE) - Role of Healthy Diet on Muscle and Bone Health
Certain clinical syndromes eg frailty, sarcopenia, dementia, depression, cognitive impairment, vision impairment and falls in older adults carry an increased risk for poor health outcomes and if identified early, can be…
- Conditions
- Muscle Weakness, Bone Health, Cognitive Decline
- Trial name
- HOPE-DIET (NCT03786835)
- Testing
- Protein supplementation and regular physical activity
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- National University Hospital, Singapore
Pre-biabetes
Effects of Milk Probiotics Intervention on Blood Glucose Control Middle-aged and Elderly People With Pre-diabetes
This study aims to conduct a 8-week probiotics intervention involving for middle-aged and elderly individuals with pre-diabetes, assessing its impact on blood glucose control in comparison to placebo
- Trial name
- NCT06972524
- Testing
- a special probiotics from Mengniu Group, supplemented with milk powder, regular milk powder does not contain any additional supplementation, and the color, flavor, shape, taste, and weight are same with the probiotic milk powder
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Huilian Zhu
Aging, Adaptation
Psycho-educational Intervention Programme for Comprehensive Preparation for Retirement: Study Protocol
Background: The transition to retirement can be a challenging event, necessitating the adjustment of new routines, roles and expectations.
- Conditions
- Aging, Adaptation, Psychosocial Factors, Psychology
- Trial name
- NCT06533202
- Testing
- Psychoeducational Programme, Education Programme
- Where
- Spain
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- University of Salamanca