Clinical trials: Older People
Alzheimer's Disease (AD), Older Adults (65 Years and Older)
Improv Music Therapy for Older Adults
Older adults and their care partners will participate in music therapy sessions for approximately 8 weeks. Before and after the 8 week study period, participants will fill out questionnaires about their mood, stress levels, and…
- Trial name
- NCT07419022
- Testing
- Clinical Improvisation
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Older People
Reablement in Residential Aged Care - a Randomized Controlled Trail
Background: The global increase in older adults presents challenges for maintaining health and autonomy in residential aged care (RAC) facilities, where passivity has been shown to often diminish quality of life.
- Trial name
- Re-RAC (NCT06793501)
- Testing
- Reablement intervention, Control group
- Where
- Sweden
- Volunteers
- 84 people
- Sponsor
- Region Örebro County
Chronic Kidney Diseases
ProtocoL for GFR Measurement Using Iohexol (SCOPE-PLUS) - A Substudy of the SCOPE Study
SCOPE-PLUS is an optional substudy of the observational SCOPE Study (Screening for Chronic Kidney Disease among Older People across Europe, NCT02691546).
- Trial name
- SCOPE-PLUS (NCT04449172)
- Where
- 5 sites in Austria, Italy and 2 more
- Volunteers
- 100 people
- Sponsor
- Istituto Nazionale di Ricovero e Cura per Anziani
Healthy Lifestyle, Physical Exercise
Lifestyle and Brain Vascular Function
Cognitive performance is negatively related to an impaired glucose metabolism, possibly due to impairments in brain vascular function.
- Conditions
- Healthy Lifestyle, Physical Exercise, Healthy Diet, Cerebrovascular Circulation
- Trial name
- NCT04234009
- Testing
- Healthy Lifestyle
- Where
- Netherlands
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Frail Elderly Syndrome
Enhanced Primary Care for Elderly
The present health care situation for the elderly in many countries is insufficient and not designed according to the health care needs of the aged population.
- Trial name
- NCT03180606
- Testing
- Multi-disciplinary and personalized primary care
- Where
- 2 sites in Sweden
- Volunteers
- 1,304 people
- Sponsor
- Region Östergötland
Serious Mental Illness, Older Adults
A Pilot Randomized Controlled Trial of the Hopeful and Healthy Living Program
The goal of this clinical trial is to learn if a novel psychosocial intervention is effective in helping adults over 50 with serious mental illness (SMI) increase their social connections and participate in more healthy lifestyle…
- Trial name
- (HHL) (NCT06940843)
- Testing
- Hopeful and Healthy Living (HHL)
- Where
- 2 sites in United States
- Volunteers
- 60 people
- Sponsor
- Boston University Charles River Campus
Quality of Hospital Entrance Reception, Social Robots
Hospitality Oriented Service Perception Evolution With Robots (HOSPER)
The HOSPER project aims to determine if using Pepper and NAO social robots at the IRCCS INRCA in Ancona's (Italy) entrance is a viable way to improve the current reception and guidance services for hospital visitors.
- Trial name
- HOSPER (NCT07002411)
- Testing
- Innovative hospital reception service with social robot NAO, Innovative hospital reception service with social robot PEPPER
- Where
- Italy
- Volunteers
- 200 people
- Sponsor
- Istituto Nazionale di Ricovero e Cura per Anziani
Prediabetes, Obesity
Veterans Achieving Weight Loss and Optimizing Resilience-Using Protein
Diabetes is a major health concern in obese older Veterans, especially in those who are African American. The negative impact of diabetes on muscle and physical function contributes to metabolic as well as physical decline and is…
- Trial name
- VALOR-UP (NCT03835416)
- Testing
- Foods rich in high quality protein
- Where
- United States
- Volunteers
- 105 people
- Sponsor
- VA Office of Research and Development
Dementia, Cognitive Impairment
Effect of Circadian Light on Hospitalized Persons With Dementia and Older Adults With Cognitive Impairments.
Light stimulates the human visual system and the biological functions in the retina, also referred to as non-visual responses, e.g. hormone production.
- Trial name
- NCT05535790
- Testing
- Naturalistic LED light, Standard/traditional lighting
- Volunteers
- 80 people
- Sponsor
- Zealand University Hospital
Diabetes, Older People
Comprehensive Approach to Reduce Elderly Functional Decline in Diabetes: the CARED Study
Importance. Conventionally, treatment goals for diabetic patients primarily target glycemic levels and traditional cardiovascular risk factors (blood pressure, lipids) control to reduce macro- and micro-vascular complications.
- Trial name
- CARED (NCT06842459)
- Testing
- Geriatric Assessment
- Where
- 2 sites in Italy
- Volunteers
- 180 people
- Sponsor
- University of Cagliari
Fall, Balanced
Development and Applications of Daily-use Fall Risk Assessment Device to Prevent Elderly People From Falling
This research attempts to develop an artificial intelligence (AI) enabled device for measuring the dynamic balance ability of older people with a sensor using an optical principle called Frustrated Total Internal Reflection.
- Trial name
- ITF-Balance (NCT05693480)
- Testing
- Balance sensor
- Where
- Hong Kong
- Volunteers
- 1,300 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Frailty, Comprehensive Geriatric Assessment
Integrated Care with GP Participation for Older Persons in the Ambulatory Care Hub: a Prospective Cohort Study.
Comprehensive Geriatric Assessment (CGA) demonstrates positive outcomes amoung community-dwelling older people living with frailty.
- Trial name
- NCT05527223
- Where
- Ireland
- Volunteers
- 303 people
- Sponsor
- University of Limerick
Muscle Weakness, Bone Health
Healthy Older People Everyday (HOPE) - Role of Healthy Diet on Muscle and Bone Health
Certain clinical syndromes eg frailty, sarcopenia, dementia, depression, cognitive impairment, vision impairment and falls in older adults carry an increased risk for poor health outcomes and if identified early, can be…
- Conditions
- Muscle Weakness, Bone Health, Cognitive Decline
- Trial name
- HOPE-DIET (NCT03786835)
- Testing
- Protein supplementation and regular physical activity
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- National University Hospital, Singapore
Frailty, Older People
A Service-Learning Program for Comprehensive Geriatric Assessment and Health Promotion in Older Adults
The GEROS Project aims to develop and implement a Service-Learning (S-L) program that integrates Comprehensive Geriatric Assessment (CGA) and health promotion, for students at the Faculty of Health Sciences and Welfare at the…
- Conditions
- Frailty, Older People, Comprehensive Geriatric Assessment, Health Promotion
- Trial name
- GEROS (NCT06890325)
- Testing
- Comprehensive Geriatric Assessment (CGA), Health education
- Where
- Spain
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Vic - Central University of Catalonia
Depressive Symptoms, Aging
Digital Gaming Intervention for Older People in Long-term Care
Older people in long-term care (LTC) are often less physically active than their community-dwelling peers. Low physical activity level is associated with more symptoms of anxiety and depression as well as with lower physical…
- Conditions
- Depressive Symptoms, Aging, Loneliness, Sedentary Behavior
- Trial name
- NCT06018974
- Testing
- Yetitablet gaming
- Where
- Finland
- Volunteers
- 49 people
- Sponsor
- University of Oulu
Cancer (Active Cancer, Meaning Not Being Cancer Free), of Any Stage and Involving Any Treatment/Care Regimen; i.e. Curative, Life-extending, or Palliative
International Study to Evaluate a Navigation Program for Older People With Cancer and Their Family Caregivers (EU NAVIGATE Study)
Most people with cancer are older, and this affects millions of Europeans yearly. Integrating high-quality, equitable, and cost-effective care across the continuum of supportive, palliative, and end-of-life care for both patients…
- Trial name
- EU NAVIGATE (NCT06110312)
- Testing
- NavCare-EU
- Volunteers
- 489 people
- Sponsor
- Vrije Universiteit Brussel
COPD, Healthy Older Adults
Acute Effects of Supramaximal High-Intensity Interval Training in People With COPD
High-intensity exercise is essential for optimal development of cardiorespiratory fitness and health. This is, however, challenging for most people with chronic obstructive pulmonary disease (COPD) due to ventilatory limitations…
- Trial name
- COPD-HIIT-AC (NCT05874999)
- Testing
- Supramaximal High-Intensity Interval Training at 60% of MPO6, Moderate-Intensity Continuous Training, Supramaximal High-Intensity Interval Training at 80% of MPO6
- Where
- Sweden
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Umeå University
Seasonal Allergic Rhinitis (SAR)
Efficacy and Safety of GSP 301 Nasal Spray in the Treatment of Seasonal Allergic Rhinitis (SAR)
Study to evaluate the efficacy, safety and tolerability of GSP 301 NS compared with placebo NS and individual monotherapy formulations for the treatment of Seasonal Allergic Rhinitis (subjects 12 years of age and older)
- Trial name
- GSP 301-304 (NCT02870205)
- Testing
- GSP 301 NS, GOM-NS, GMM-2 NS
- Where
- 43 sites in United States
- Volunteers
- 1,176 people
- Sponsor
- Glenmark Specialty S.A.
Influenza
Immunogenicity and Safety Study of GlaxoSmithKline (GSK) Biologicals' Influenza Vaccine, Fluarix®/Influsplit SSW® (2013/2014 Season), in Adults 18 Years of Age and Older
The purpose of this study is to assess, in adults 18 years of age and above, the immunogenicity and reactogenicity of the seasonal influenza vaccine, Fluarix/Influsplit SSW 2013/2014, containing the three vaccine influenza…
- Trial name
- NCT01884519
- Testing
- Fluarix/Influsplit SSW® (2013-2014 season)
- Where
- 4 sites in Germany
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Coronavirus
Omicron BA.4/5-Delta Strain Recombinant Novel Coronavirus Protein Vaccine (CHO Cells)
Popular title: Clinical study of Omicron BA.4/5-Delta strain recombinant novel coronavirus protein vaccine (CHO cells). Purpose of the study: Main objectives: To evaluate the immunogenicity and safety of Omicron BA.4/5-Delta…
- Trial name
- NCT05850507
- Testing
- Omicron BA.4/5-Delta strain recombinant novel coronavirus protein vaccine (CHO cells), Recombinant novel coronavirus protein vaccine (CHO cells)
- Where
- China
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Anhui Zhifei Longcom Biologic Pharmacy Co., Ltd.