Clinical trials: Older Patients
Older Adults, Nursing Homes
Technology Use, Safe Health Information, and Artificial Intelligence Among Older Adults
Objective The aim of this research is to evaluate how improving the technology use skills of older adults in nursing homes changes their perceptions of access to safe health information and the use of artificial intelligence.
- Conditions
- Older Adults, Nursing Homes, Artifical Intelligence, Technology Use
- Trial name
- NCT07881614
- Testing
- E-Health Literacy Based Education
- Where
- Turkey (Türkiye)
- Volunteers
- 46 people
- Sponsor
- Ondokuz Mayıs University
Older Adults With Complex Care Needs
Digital Bridge: Using Technology to Support Patient-centered Care Transitions From Hospital to Home
Older adults who live with multiple chronic conditions are more likely to experience frequent admissions and discharges from hospital. These transitions are often challenging and leave people at risk of readmission.
- Trial name
- DB (NCT04287192)
- Testing
- Digital Bridge:Tool Intervention
- Where
- Canada
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Mount Sinai Hospital, Canada
Gastrointestinal Cancers, Frailty
Longitudinal Geriatric Vulnerability, Chemotherapy Toxicity, and Functional Outcomes in Older Adults With Gastrointestinal Cancer
Older adults with gastrointestinal cancers may be more likely to experience side effects from chemotherapy and difficulties with everyday activities. These problems are not always explained by age alone.
- Conditions
- Gastrointestinal Cancers, Frailty, Sarcopenia in Elderly, Malnutrition Elderly
- Trial name
- VITAL-GI (NCT07184047)
- Testing
- Standard-of-Care Systemic Chemotherapy
- Where
- Turkey (Türkiye)
- Volunteers
- 132 people
- Sponsor
- Ankara Etlik City Hospital
Preoperative Prehabilitation in Older Adults Undergoing Hepatectomy
Prehabilitation Before Liver Surgery in Older Adults
Many older adults who need liver surgery (hepatectomy) are physically weak before their operation. This can make recovery harder and may lead to more complications after surgery.
- Trial name
- NCT07877311
- Testing
- Preoperative Prehabilitation Program
- Where
- 6 sites in China
- Volunteers
- 500 people
- Sponsor
- Lining Xu
Balance Control in Elderly, Falls (Accidents) in Old Age
Turkish Adaptation of the Multidimensional Falls Efficacy Scale in Older Adults
Falls are a major health concern among older adults and can lead to injuries, reduced independence, and a lower quality of life.
- Conditions
- Balance Control in Elderly, Falls (Accidents) in Old Age, Older Adults (65 Years and Older)
- Trial name
- NCT07878832
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people
- Sponsor
- Gazi University
Chronic Insomnia, Older Adults
Brief Behavioral Therapy for Insomnia (BBTi) in Middle-aged and Older Adults With Chronic Insomnia
This study aims to investigate whether a nurse-led brief behavioral therapy can effectively improve chronic insomnia and sleep health in older adults.
- Conditions
- Chronic Insomnia, Older Adults, Sleep Hygiene, Sleep Health
- Trial name
- NCT06073990
- Testing
- Brief Behavioral Treatment for Insomnia (BBTi)
- Where
- Taiwan
- Volunteers
- 80 people
- Sponsor
- National Cheng-Kung University Hospital
Older People, Pain
Exploring the Acute and Dynamic Relationships Between Movement and Pain in Older Adults With Musculoskeletal Pain
The purpose of this research study is to evaluate the effect of brief bouts of intermittent walking on bodily pain, pain during movement, and how the body adapts to musculoskeletal pain in older adults.
- Trial name
- NCT06886906
- Testing
- Intermittent light walking, uninterrupted sitting
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Indiana University
ASA Class III/IV Patients, COPD III/IV
Remimazolam Versus Propofol for Procedural Sedation in Gastrointestinal Endoscopy: A Single-Centre Prospective Observational Comparative Study in a High-Risk Population
Remimazolam is a new, ultra-short-acting benzodiazepine approved in Romania for procedural sedation. It shows significant clinical benefits compared to other sedatives like Propofol or Midazolam, especially in elderly or…
- Conditions
- ASA Class III/IV Patients, COPD III/IV, Age 65 and Older, Multiple Organ Failure
- Trial name
- NCT07362173
- Testing
- Administering remimazolam, Administering propofol
- Where
- Romania
- Volunteers
- 203 people
- Sponsor
- Iuliu Hatieganu University of Medicine and Pharmacy
Fall Risk in Middle-Aged and Older Adults
Short-term Changes in Postural Sway, Gait, and fNIRS-derived Cortical Metrics After a 4-week AI-assisted Exercise Program: a Single-arm Pre-post Study
This single-arm pre-post study will enroll 50 participants aged 52-65 years who will undergo a 4-week AI-assisted exercise intervention.
- Trial name
- NCT07876011
- Testing
- AI-assited exercise
- Where
- China
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Peking University Third Hospital
Older Adults (60 - 85 Years Old), Sarcopenia
Evaluation of Sarcopenia and Muscle Biomechanics in Older Adults After Lumbar Fusion Surgery
Abstract Background: Lumbar fusion (LF) surgery successfully restores the mechanical stability of the spine; however, postoperative kinesiophobia and complications can trigger secondary sarcopenia.
- Conditions
- Older Adults (60 - 85 Years Old), Sarcopenia, Lumbar Fusion Surgery, Low Back Pain
- Trial name
- NCT07866807
- Where
- Turkey (Türkiye)
- Volunteers
- 51 people
- Sponsor
- Karamanoğlu Mehmetbey University
Older Patients, Surgery
Dexmedetomidine-esketamine and tDCS for Prevention of Neurocognitive Complications After Surgery
Neurocognitive complications, mainly delirium and neurocognitive disorders, are common cerebral complications in older patients after surgery and associated with worse outcomes.
- Conditions
- Older Patients, Surgery, Dexmedetomidine, Esketamine
- Trial name
- NCT07576517
- Testing
- Dex-Esk, Active tDCS
- Where
- 6 sites in China
- Volunteers
- 1,996 people, healthy volunteers welcome
- Sponsor
- Peking University First Hospital
Older Patients, Surgery
Long-term Follow-up of Dexmedetomidine-esketamine and tDCS for Neurocognitive Complications After Surgery
Neurocognitive complications, mainly delirium and neurocognitive disorders, are common cerebral complications in older patients after surgery and associated with worse long-term outcomes.
- Conditions
- Older Patients, Surgery, Dexmedetomidine, Esketamine
- Trial name
- NCT07576543
- Testing
- Dex-Esk, Active tDCS
- Where
- 6 sites in China
- Volunteers
- 1,996 people, healthy volunteers welcome
- Sponsor
- Peking University First Hospital
Mobility Impairment, Community Dwelling Older Adults
Motor Imagery and Turning Practice to Improve Mobility: Pilot Trial
The goal of this clinical trial is to evaluate whether combining in-person turning practice with home-based Motor Imagery Therapy (MIT) is feasible and may improve mobility in community-dwelling older adults aged 65 years and…
- Trial name
- MI-TURN (NCT07705360)
- Testing
- Motor Imagery Therapy, Stress Management Education, Locomotor Turning Practice
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Boise State University
Physical Function in Older Adults
Application-Based Personalized Exercise Program in Older Adults
This study aims to evaluate the feasibility, usability, adherence, and potential effects of an application-based personalized multicomponent exercise program in older adults.
- Trial name
- NCT07872176
- Testing
- Application-Based Personalized Multicomponent Exercise Program
- Where
- South Korea
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Korea University Guro Hospital
Physical Performance, Quality of Life, and Mental Health in Older Adults
Comparison of Physical Performance, Quality of Life and Mental Health in Hiking and Sedentary Geriatric Individuals
This observational study aims to compare physical performance, quality of life, and mental health levels between older adults who participate in hiking at least once a week for at least 6 months and sedentary older adults.
- Trial name
- NCT07867756
- Where
- Turkey (Türkiye)
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Halic University
Postoperative Mortality, Frailty at Older Adults
Predictive Value of Frailty Scores and Admission Laboratory Markers for Postoperative ICU Mortality
This prospective observational study aims to evaluate the predictive value of the Clinical Frailty Scale (CFS), the Katz Activities of Daily Living (ADL) scale, and admission laboratory markers for postoperative mortality among…
- Conditions
- Postoperative Mortality, Frailty at Older Adults, Activities of Daily Living, Postoperative Complications
- Trial name
- GERI-MORTAL (NCT07279519)
- Where
- Turkey (Türkiye)
- Volunteers
- 393 people
- Sponsor
- Malatya Egitim Ve Arastirma Hastanesi
Older Adults (60 - 85 Years Old)
Multiple Breathing Training on Pulmonary Function and Respiratory Muscle Strength in Older Adults
This study were to investigate the effects of multiple breathing training on pulmonary function, respiratory muscle strength, chest expansion, fractional exhaled nitric oxide (FeNO), aerobic capacity, and dyspnea symptoms in…
- Trial name
- NCT07459153
- Testing
- Multiple breathing training
- Where
- Thailand
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Chulalongkorn University
Older Adults (65 Years and Older), Polypharmacy (People Under Treatment With 5 or More Drugs)
Impact of Pharmacotherapy Optimization in Polymedicated Lebanese Older Adults in Primary Health Care Centers
Why are the researchers doing this study? Many older adults take five or more medicines every day. Some of these medicines may no longer help them. Some may even cause harm, such as falls, confusion or tiredness.
- Conditions
- Older Adults (65 Years and Older), Polypharmacy (People Under Treatment With 5 or More Drugs), Primary Health Care, Social Determinants of Health (SDOH)
- Trial name
- PHARMACT-PHC (NCT07866677)
- Testing
- Structured pharmacotherapy optimization, Usual Care
- Where
- Lebanon
- Volunteers
- 452 people
- Sponsor
- National Institute of Public Health, Clinical Epidemiology, and Toxicology-Lebanon (INSPECT-LB)
Frailty at Older Adults, Mastication
Oral Function Intervention in Community-Dwelling Older Adults
Oral frailty is a potentially reversible condition associated with physical frailty and functional decline in older adults. Interventions targeting oral function may therefore improve broader physical health.
- Conditions
- Frailty at Older Adults, Mastication, Physical Functional Performance, Aging
- Trial name
- NCT07866781
- Testing
- Integrated Oral Function Intervention
- Where
- Taiwan
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Kaohsiung Medical University Chung-Ho Memorial Hospital
Healthy, Young Adults
Sensory Interaction and Balance Control During Standing and Walking in Healthy Young and Older Adults
This project is designed to: a) develop a new test called Sensory Integration in Walking (SensIWalk) Test which would allow us to evaluate sensory interaction process in locomotion assess whether Locomotor CTSIB and to…
- Conditions
- Healthy, Young Adults, Older Adults (65 Years and Older), Elderly
- Trial name
- NCT06629922
- Testing
- No intervention
- Where
- Belgium
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Hasselt University