Clinical trials: Older Adult
Aging
A New Adaptive Physical Activity Technology in Older Adults
The purpose of this study is to explore the feasibility and acceptability of a new physical activity technology (Jintronix) based on TV screen, virtual games and motion sensing cameras among pre-disabled older adults.
- Trial name
- Jintronix (NCT02467491)
- Testing
- Jintronix
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- University of Florida
Frail Elderly w/ Multimorbidity & Functional Limitations
The PAtient-Centred Team - Effectiveness and Cost-effectiveness Study
There is an urgent need to develop new care models for patients with long-term and complex needs. Our goal is services that are seamless, pro-active and person-oriented.
- Trial name
- PACT (NCT02541474)
- Testing
- Integrated care
- Where
- Norway
- Volunteers
- 1,200 people
- Sponsor
- University Hospital of North Norway
Healthy
ActivE³ - Everyone, Everywhere, Everyday WP 2 - Personalized Data-driven Coaching Platform for Stimulating and Promoting Active Lifestyle and Health Risk Prevention
The objective of WP2 of the Active3 project is to develop a digital solution for promoting and monitoring physical activity in social settings (real or virtual) that implements a Preventive Medicine approach to healthy aging.
- Trial name
- Active3-WP2 (NCT07350915)
- Testing
- Digital Therapeutics
- Where
- Italy
- Volunteers
- 237 people, healthy volunteers welcome
- Sponsor
- Politecnico di Milano
Anger Problems, Spiritual Well-being
Laughter Yoga's Impact on Children's Anger and Well-Being
This study aims to evaluate the effects of laughter yoga on anger levels and mental well-being in schoolchildren. Research indicates that laughter yoga has the potential to reduce stress and improve communication skills.
- Trial name
- NCT06827015
- Testing
- Laughter-Based Anger Reduction Program
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 96 people
- Sponsor
- Mersin University
Falls in the Elderly
Follow-up of Elderly Subjects With Falls Recruited in the Geriatric Departments of Several French Hospitals
Falls are the leading cause of accidental death among the elderly, with nearly 8,000 deaths per year in France, including more than 950 deaths on average per year in the Northwest interregion between 2006 and 2013.
- Trial name
- PREMOB (NCT05281835)
- Where
- France
- Volunteers
- 1,000 people
- Sponsor
- University Hospital, Lille
Acute Respiratory Infection
Efficacy and Safety of Polyoxidonium, Nasal and Sublingual Spray, 6 mg/ml in Children Aged 1-12 Years With ARI
The purpose of this study is is to demonstrate superiority of Polyoxidonium, nasal and sublingual spray, 6 mg/ml over placebo in children aged from 1 to 12 years with acute respiratory viral infections.
- Trial name
- NCT03840135
- Testing
- Polyoxidonium 6 mg/ml
- Where
- 11 sites in Russia
- Volunteers
- 172 people
- Sponsor
- NPO Petrovax
Sarcopenia in Elderly
Evaluation of the JUICE HA® as an Anti-sarcopenia
This study plans to recruit 60 participants aged 65 years and older who have been diagnosed with sarcopenia by a physician. Participants will be randomly assigned into JUICE HA® supplement and placebo group.
- Trial name
- NCT06950125
- Testing
- JUICE HA® supplement
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- China Medical University Hospital
Pneumococcal Pneumonia, Pneumonia, Bacterial
Phase I to Test a New Pneumococcal Vaccine
To obtain first-in-human data on a new candidate vaccine against Streptococcus pneumoniae in healthy adult and elderly volunteers.
- Trial name
- NCT03303976
- Testing
- Bioconjugate pneumococcal vaccine, Multivalent plain polysaccharide vaccine
- Where
- Germany
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- LimmaTech Biologics AG
Potassium, Decreased Level, Postsurgical Pain, Chronic
Serum Potassium as a Predictor of Clinical Outcomes in an Older Patient Cohort With Chronic Postsurgical Pain
Perioperative serum potassium in patients over 65 impacts recovery, quality of life and physical functioning. While perioperative serum potassium is an important preoperative risk factor for poor surgical outcomes in older…
- Trial name
- NCT05385640
- Testing
- NO intervention
- Where
- China
- Volunteers
- 3,088 people
- Sponsor
- Chinese PLA General Hospital
Sleep
Energy-efficient and Health Promoting Light for Elderly People
to investigate the effect of two lightning conditions on sleep hypothesizing that sleep length is influenced by the color of light during daytime
- Trial name
- light-age (NCT02216318)
- Testing
- blue light
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Glostrup University Hospital, Copenhagen
Acute Myeloid Leukemia
Venetoclax and HMA Treatment of Older and Unfit Adults With FLT3 Mutated Acute Myeloid Leukemia (AML) (A MyeloMATCH Treatment Trial)
This phase II MyeloMATCH treatment trial compares the usual treatment of azacitidine and venetoclax to the combination treatment of azacitidine, venetoclax and gilteritinib in treating older and unfit patients with acute myeloid…
- Trial name
- NCT06317649
- Testing
- Azacitidine, Biospecimen Collection, Bone Marrow Aspiration
- Where
- 229 sites in United States, Canada and 1 more
- Volunteers
- 147 people
- Sponsor
- National Cancer Institute (NCI)
Cardiovascular Risk Factor
Prognosis in the Elderly Chinese: the Northern Shanghai Study
The Northern Shanghai Study is a prospective community-based study, which is aimed to investigate the prognostic factors, including conventional cardiovascular risk factors and asymptomatic target organ damage, for mortality and…
- Trial name
- NSS (NCT02368938)
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- Shanghai 10th People's Hospital
Functional Limitation
Metabolic Costs of Daily Activities in Older Adults
The work will evaluate the metabolic costs for daily activities across the lifespan and evaluate the influence of having functional impairments.
- Trial name
- CHORES-XL (NCT02129855)
- Where
- United States
- Volunteers
- 269 people, healthy volunteers welcome
- Sponsor
- University of Florida
Age-Related Cognitive Decline, Age-Related Memory Disorders
Memory Improvement With Docosahexaenoic Acid Study (MIDAS)
The purpose of this study is to investigate the effect of docosahexaenoic acid (DHA, 22:6n-3) in improving cognitive functions in subjects with age-related cognitive decline.
- Trial name
- MIDAS (NCT00278135)
- Where
- 14 sites in United States
- Volunteers
- 485 people
- Sponsor
- dsm-firmenich Switzerland AG
New Biomarkers for Measuring Vitamin D Level
A New Paradigm for Vitamin D Sufficiency
Although the African-American (AA) population tends to have lower serum 25(OH)D levels compared to whites, there is no evidence that the lower 25(OH)D levels in African-Americans are harmful.
- Trial name
- NCT02969850
- Testing
- Vitamin D Supplementation, Calcium
- Where
- United States
- Volunteers
- 444 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Diabetes Mellitus, Non-Insulin Dependent
Evaluation of SCOUT DS in Subjects With Type 2 Diabetes #2
The primary objective of the trial is to collect SCOUT DS and Hemoglobin A1c measurements of subjects who have been diagnosed with Type 2 diabetes.
- Trial name
- TCOYD2 (NCT01346046)
- Where
- United States
- Volunteers
- 264 people, healthy volunteers welcome
- Sponsor
- VeraLight, Inc.
Cognition, Diabetes Mellitus, Type 2
Adaptive Cognitive Training on Cognitive Function in Elderly Diabetes Patients in the Community
Objective A growing body of evidence supports diabetes as a risk factor for cognitive decline. Diabetes is significantly associated with accelerated cognitive decline, poorer cognitive function, and mild cognitive impairment and…
- Conditions
- Cognition, Diabetes Mellitus, Type 2, Aging
- Trial name
- NCT06524388
- Testing
- adaptive cognitive training
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Fanfan Zheng
Dietary Supplement, Placebo
Neuromuscular Responses to Acute Beetroot Ingestion in Women Older Adults
Beetroot juice supplementation has shown the capacity for provoking different physiological effects (e.g. vasodilation and muscle contraction increments).
- Trial name
- BEET_ELDERLY (NCT05337527)
- Testing
- beetroot juice
- Where
- Spain
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Universidad Francisco de Vitoria
Chronic Kidney Disease, Chronic Renal Insufficiency
Growth Hormone Treatment in Infants Aged 1 to 2 Years With Chronic Renal Insufficiency (CRI) and Growth Retardation.
This trial is conducted in Europe. Objective(s): To evaluate the effect of human growth hormone on infants aged 1 to 2 years with chronic renal insufficiency (CRI) and growth retardation despite an adequate dietary intake.
- Trial name
- NCT00184769
- Testing
- somatropin
- Where
- 20 sites in Portugal, Spain
- Volunteers
- 16 people
- Sponsor
- Novo Nordisk A/S
Functional Fitness Deterioration, Gait Balance
Health and Gait Outcomes in Elderly Dancers Compared to Inactive Adults
The aim of this observational study is to assess functional fitness and spatial-temporal gait parameters in individuals aged 65 years and over who regularly participate in senior dance classes.
- Trial name
- NCT07170241
- Where
- Hungary
- Volunteers
- 180 people
- Sponsor
- Dr. Kovács Éva
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