Clinical trials: Obsessive-compulsive Disorder (OCD)
Obsessive-Compulsive Disorder
Internet-delivered CBT for Adolescents With OCD: A Randomized Controlled Study
The effect of Internet-delivered Cognitive Behavior Therapy (ICBT) on adolescents (12 to 17 years) with Obsessive-Compulsive Disorder is studied. Participants are randomized to either ICBT or a no-treatment condition.
- Trial name
- BiPOCD (NCT02191631)
- Testing
- Internet-delivered Cognitive Behavior Therapy
- Where
- Sweden
- Volunteers
- 67 people
- Sponsor
- Karolinska Institutet
Obsessive-Compulsive Disorder
Metacognitive Therapy for Patients With Obsessive-Compulsive Disorder
Cognitive behavior therapy is the most effective treatment of obsessive-compulsive disorder. However, the majority of treated patients remain symptomatic.
- Trial name
- NCT01483339
- Testing
- Metacognitive Therapy, Exposure and Response Prevention
- Where
- Germany
- Volunteers
- 37 people
- Sponsor
- Philipps University Marburg
Obsessive-Compulsive Disorder
Pilot Study of CBT With tDCS for Adults Being Treated for Obsessive Compulsive Disorder
This pilot study aims to compare the effect of transcranial direct current stimulation (tDCS) versus sham stimulation, delivered immediately prior to cognitive-behavioral therapy (CBT) for obsessive-compulsive disorder (OCD), on…
- Trial name
- NCT05964998
- Testing
- transcranial direct current stimulation
- Where
- United States
- Sponsor
- Rogers Behavioral Health
Obsessive-Compulsive Disorder
Trial of MR-guided Focused Ultrasound (MRgFUS) Bilateral Capsulotomy for the Treatment of Refractory Obsessive-compulsive Disorder (OCD)
The proposed study is to evaluate the safety and initial efficacy of MRgFUS for patients with treatment-refractory OCD. This study is designed as a prospective, single arm, nonrandomized study.
- Trial name
- NCT03156335
- Testing
- Focused Ultrasound
- Where
- 2 sites in Canada
- Volunteers
- 12 people
- Sponsor
- Sunnybrook Health Sciences Centre
Stroke, Ischemic, Stroke Hemorrhagic
Transnasal Induction of Normothermia for Neurogenic Fever
The objective of this study is to evaluate the efficacy of the COOLSTAT® Transnasal Thermal Regulating Device in reducing temperature in a population of febrile subjects who meet the inclusion/exclusion criteria.
- Conditions
- Stroke, Ischemic, Stroke Hemorrhagic, Seizures, Metabolic Encephalopathy
- Trial name
- NCT06038513
- Testing
- Transnasal Thermal Regulating Device
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- CoolTech LLC
Obsessive - Compulsive Disorder
Efficacy and Underlying Mechanisms of Group-Based Natural Psychotherapy for Anxiety Disorder
This study aims to preliminarily explore the intervention effect and feasibility of group natural psychotherapy (a new Eastern culture-based psychotherapy method) for patients with anxiety disorder through a randomized controlled…
- Trial name
- NCT07518264
- Testing
- Group-based Natural Psychotherapy
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Beijing HuiLongGuan Hospital
Obsessive-Compulsive Disorder in Children, Obsessive-Compulsive Disorder in Adolescence
Treatment Effects of Family Based Cognitive Therapy in Children and Adolescents With Obsessive Compulsive Disorder
To investigate the benefits and harms, and the neural and neurocognitive mediators of treatment response, in family-based cognitive behavioural therapy versus family-based psychoeducation and relaxation training in children and…
- Trial name
- TECTO (NCT03595098)
- Testing
- Family Based Cognitive Behavioural Therapy, Family Based Psychoeducation/Relaxation Training
- Where
- Denmark
- Volunteers
- 128 people
- Sponsor
- Anne Katrine Pagsberg
Obsessive Compulsive Disorder (OCD)
NAC for Treatment-Resistant OCD and Other Related Disorders
This is a randomized, double-blind, placebo-controlled study investigating N-acetylcysteine (NAC) as an augmentation therapy for individuals with treatment-resistant obsessive-compulsive disorder (TR-OCD), studied within a…
- Trial name
- NCT06956157
- Testing
- N-Acetylcysteine Tablets
- Where
- China
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Guangdong Provincial People's Hospital
Obsessive-Compulsive Disorder, Cognitive Behavioral Therapy
Cognitive Behavioral Group Treatment for Obsessive-compulsive Disorder in Youth
Obsessive-compulsive disorder (OCD) is a debilitating disorder characterized by unwanted intrusive thoughts and disrupting repetitive rituals.
- Conditions
- Obsessive-Compulsive Disorder, Cognitive Behavioral Therapy, Adolescent
- Trial name
- NCT04891367
- Testing
- Cognitive behavioral therapy
- Where
- Denmark
- Volunteers
- 72 people
- Sponsor
- Aarhus University Hospital
Obsessive - Compulsive Disorder, Tic Disorder, Chronic Motor or Vocal
Integrating Exposure and Response Prevention and Habit Reversal Techniques to Treat a Tourettic Subtype of Obsessive-Compulsive Disorder (Tourettic OCD)
Obsessive-Compulsive Disorder and Tic Disorders frequently co-occur, and a subgroup of patients - those with a Tourettic Subtype of OCD (TOCD) - present with concurrent obsessive-compulsive and tic symptoms.
- Conditions
- Obsessive - Compulsive Disorder, Tic Disorder, Chronic Motor or Vocal, Tic Disorders, Tic Disorder, Combined Vocal and Multiple Motor
- Trial name
- TORCH (NCT07725926)
- Testing
- Exposure and Response Prevention (ERP), Habit Reversal Training (HbRT, Psychoeducation and Supportive Intervention
- Where
- 2 sites in United Kingdom
- Volunteers
- 40 people
- Sponsor
- University College London Hospitals
Obsessive Compulsive Disorder
Study of Magnetic Brain Stimulation in Treatment of Obsessive Compulsive Disorder
In a preliminary pilot study, the investigators tested the efficacy of rTMS over the medial prefrontal cortex in symptom profiles of obsessive compulsive disorder (OCD) patients.
- Trial name
- rTMS (NCT02018185)
- Testing
- Transcranial Magnetic Stimulation
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- University of Manitoba
Obsessive-Compulsive Disorder
Towards Remission and Full Recovery From Obsessive-compulsive Disorder
Obsessive-compulsive disorder (OCD) is a disabling psychiatric illness that is characterized by distressing obsessional thoughts and time-consuming compulsive rituals.
- Trial name
- RCT2023 (NCT06318806)
- Testing
- Psychotherapy
- Where
- Canada
- Volunteers
- 160 people
- Sponsor
- Ciusss de L'Est de l'Île de Montréal
Obsessive - Compulsive Disorder
Neural Mechanisms of the Sensorymotor Circuit in Sensory Phenomena in OCD
The goal of this clinical study is to investigate the neural mechanisms of abnormal sensory phenomena in patients with Obsessive-Compulsive Disorder and to evaluate whether modulation of the insula-supplementary motor area…
- Trial name
- NCT07480408
- Testing
- repetitive transcranial magnetic stimulation (rTMS)
- Where
- China
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Shanghai Mental Health Center
Pathologic Skin Picking, Neurotic Excoriation
N-Acetyl Cysteine in Pathologic Skin Picking
The goal of the proposed study is to evaluate the comparative efficacy of N-acetyl cysteine to placebo in pathologic skin picking.
- Conditions
- Pathologic Skin Picking, Neurotic Excoriation, Psychogenic Excoriation, Dermatillomania
- Trial name
- NCT01063348
- Testing
- N-Acetyl Cysteine
- Where
- United States
- Volunteers
- 66 people
- Sponsor
- University of Chicago
Tourette's Syndrome, Tourette Syndrome
Subthalamic Stimulation in Tourette's Syndrome
The main objective of this project is to evaluate the efficacy of subthalamic nucleus deep brain stimulation (STN DBS) in treating motor and phonic tics in medically refractory Tourette's syndrome (TS).
- Conditions
- Tourette's Syndrome, Tourette Syndrome, Gilles de la Tourette Syndrome, Tourette Disorder
- Trial name
- STN-DBSinTS (NCT02619084)
- Testing
- STN DBS
- Where
- Italy
- Volunteers
- 10 people
- Sponsor
- Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta
Obsessive-Compulsive Disorder
Safety and Effectiveness of Capsulotomy in Refractory OCD
Obsessive-compulsive disorder (OCD) is a severely disabling psychiatric disorder with a worldwide lifetime prevalence of 2-3% (Islam et al., 2015).Despite the efficacy of pharmacological and behavioural treatment methods for most…
- Trial name
- NCT02375152
- Testing
- Anterior Capsulotomy
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Ruijin Hospital
Obsessive - Compulsive Disorder
Accelerated rTMS in Hospitalized Patients With OCD: a Feasibility and Mechanistic Study
This study investigates a new treatment approach for Obsessive-Compulsive Disorder (OCD), a condition characterized by unwanted repetitive thoughts and behaviors.
- Trial name
- arTMS-OCD (NCT07135414)
- Testing
- iTBS, dTMS, ERP
- Where
- Belgium
- Volunteers
- 60 people
- Sponsor
- University Hospital, Ghent
Obsessive-Compulsive Disorder (OCD)
Metacognitive Therapy for Obsessive-Compulsive Disorder
Cognitive behavior therapy is the most effective treatment of obsessive-compulsive disorder. However, the majority of treated patients remain symptomatic.
- Trial name
- NCT02867449
- Testing
- Metacognitive Therapy, Exposure and Response Prevention
- Where
- 2 sites in Germany
- Volunteers
- 74 people
- Sponsor
- University of Leipzig
Psychotherapy Intervention Evaluation
iCBT for Children and Adolescents With Obsessive-compulsive Disorder II
Internet-based psychotherapy for children and adolescents with obsessive-compulsive symptoms and an age of 6 to 18 years. Sessions are verified with teleconferencing with an psychotherapist, children and their parents.
- Trial name
- NCT05037344
- Testing
- Cognitive-behavioral psychotherapy
- Where
- Germany
- Volunteers
- 60 people
- Sponsor
- University Hospital Tuebingen
Obsessive-Compulsive Disorder
Tolerability and Efficacy of High Dose Escitalopram for the Treatment of Obsessive-Compulsive Disorder (OCD)
Objectives: To evaluate tolerability and efficacy of escitalopram treatment in high dose than 20-50 mg/d in out-patients with OCD Type of the study: Open label, prospective study.
- Trial name
- NCT00305500
- Testing
- escitalopram
- Where
- Israel
- Volunteers
- 100 people
- Sponsor
- Abarbanel Mental Health Center