Clinical trials: Obsessive-Compulsive Symptoms
Schizophrenia, Treatment Resistant Depression (TRD)
Treatment Resistance in Psychiatric Disorders: the Search for Biological Markers Predictive of Response to Treatment
The disruption of immune system is a key candidate in the pathogenesis of psychiatric disorders, especially those resistant to traditional treatments.
- Conditions
- Schizophrenia, Treatment Resistant Depression (TRD), Bipolar Disorder (BD), Catatonia
- Trial name
- BIO-INM (NCT07741981)
- Testing
- Blood sampling, lumbar puncture, stool sampling, skin microbiopsy and psychometrics scales
- Where
- France
- Volunteers
- 700 people
- Sponsor
- Centre Hospitalier St Anne
Schizophrenia, Obsessive-Compulsive Symptoms
Repetitive Transcranial Magnetic Stimulation (rTMS) as an add-on Treatment for Resistant Obsessive-compulsive Symptoms in Patients With Schizophrenia
This is a study to evaluate the efficacy of rTMS for relief of obsessive-compulsive symptoms in patients with schizophrenia.
- Trial name
- NCT02105064
- Testing
- Active rTMS
- Where
- Brazil
- Volunteers
- 12 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Depression, Anxiety Disorders
School Withdrawal in Adolescents
The aim of the study is to evaluate the impact of the outpatient ambulatory child psychiatric care system on the functioning of anxio-depressive adolescents in school retreat by describing the modalities of individual psychic…
- Conditions
- Depression, Anxiety Disorders, Obsessive-Compulsive Disorder, Behavior Disorders
- Trial name
- DESCOL (NCT03904784)
- Testing
- school withdrawal teenagers
- Where
- France
- Volunteers
- 8 people
- Sponsor
- Centre Hospitalier Intercommunal Creteil
Depression, Dysthymic Disorder
Internet-delivered Transdiagnostic Intervention for Anxiety and Depression
Objectives 1. To test the effectiveness and acceptability of an augmented internet-supported transdiagnostic intervention in Romania. 2.
- Conditions
- Depression, Dysthymic Disorder, Panic Disorder, Social Phobia
- Trial name
- iTAD (NCT02739607)
- Testing
- Transdiagnostic program
- Where
- Romania
- Volunteers
- 100 people
- Sponsor
- West University of Timisoara
OCD
Pilot Study to Evaluate Escitalopram in Obsessive-compulsive Disorder
This study will determine the safety and effectiveness of escitalopram (Lexapro)in treating obsessive-compulsive disorder (OCD) symptoms.
- Trial name
- NCT00215137
- Testing
- escitalopram
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- Duke University
Obsessive-compulsive Disorder
Booster as an Adjunct to Internet-based Cognitive Behavior Therapy (CBT)
In this trial, we test if adding an Internet-based booster program to regular Internet-based cognitive behavior therapy (ICBT) is effective for patients with obsessive-compulsive disorder (OCD).
- Trial name
- NCT01525576
- Testing
- Booster
- Where
- Sweden
- Volunteers
- 98 people
- Sponsor
- Karolinska Institutet
Obsessive-Compulsive Disorder and Symptoms
Brief Anxiety Sensitivity Treatment for Obsessive Compulsive Symptoms
Obsessive-compulsive disorder (OCD), characterized by recurrent obsessions and/or compulsions, is a disabling psychiatric condition affecting approximately 2-3% of the population.
- Trial name
- COAST (NCT02635178)
- Testing
- Cognitive Anxiety Sensitivity Treatment, Physical Health Education Training
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Florida State University
Bipolar Affective Disorders, Cyclothymic Disorder
The Influence of the Menstrual Cycle on Lithium and Sertraline Blood Levels
The aim of this study is to determine whether blood levels of lithium or sertraline are affected by different phases of the menstrual cycle and whether there is an effect on psychiatric symptoms.
- Conditions
- Bipolar Affective Disorders, Cyclothymic Disorder, Schizoaffective Disorder, Major Depressive Disorder
- Trial name
- NCT01385709
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- Weill Medical College of Cornell University
Hoarding Disorder
Comparison of Treatment for Hoarding Disorder
This study proposes to compare two forms of treatment for Hoarding Disorder (HD), a common and impairing neuropsychiatric syndrome that has a profound impact on the lives and functioning of individuals, families, and society.
- Trial name
- NCT02040805
- Testing
- Group Cognitive Behavioral Therapy, Peer Facilitated Support Group
- Where
- 2 sites in United States
- Volunteers
- 323 people
- Sponsor
- University of California, San Francisco
Well-Being, Psychological, Mood Disturbance
Neurofeedback and Well-Being Among People With Co-Occurring Obsessive Compulsive Disorder and Post-traumatic Stress Symptoms
The proposed study will collect novel data evaluating the feasibility of a neurofeedback training program delivered to prospective clients with a history of clinically concerning trauma-related mental health symptoms who are on a…
- Conditions
- Well-Being, Psychological, Mood Disturbance, Emotional Regulation, Dissociation
- Trial name
- NCT07217925
- Testing
- Neuroptimal (Zengar, Inc.) Neurofeedback
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Wayne State University
Obsessive-Compulsive Symptoms, Cognitive Control
Brain Function and Cognitive Control Training in Children With Obsessive-Compulsive Symptoms
The goal of this clinical trial is to learn about brain function and cognition in children ages 8-12 who have subclinical obsessive-compulsive symptoms (OCS), such as unwanted thoughts or repetitive behaviors.
- Trial name
- AKILI - OCS (NCT07839013)
- Testing
- Cognitive Control Training
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Columbia University
Obsessive-compulsive Disorders and Symptoms, Obsessive-Compulsive Disorder
Inference-Based Cognitive Therapy Versus Exposure and Response Prevention for Obsessive-Compulsive Disorder
Obsessive-compulsive disorder (OCD) is a highly disabling psychiatric illness, characterized by obsessional thoughts that cause patients to perform time-consuming and distressing compulsive rituals.
- Trial name
- RCT_TOC_16 (NCT03677947)
- Testing
- Exposure and response prevention, Inference-based cognitive therapy
- Where
- Canada
- Volunteers
- 150 people
- Sponsor
- Centre de Recherche de l'Institut Universitaire en santé Mentale de Montréal
Schizophrenia OCD, Obsessive Compulsive Disorder
Aripiprazole in the Treatment of Patients With Schizophrenia and Symptoms of Obsessive Compulsive Disorder (OCD)
To evaluate the effectiveness of flexible doses (15-30mg) of Aripiprazole in the treatment of patients with schizophrenia and co-morbid symptoms of OCD in the outpatient setting.
- Trial name
- NCT00374348
- Testing
- Aripiprazole
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Jamaica Hospital Medical Center
Obsessive-Compulsive Disorder, Anxiety Disorders
Pharmacogenetics of Antidepressant-Induced Disinhibition
The purpose of this study is to identify pharmacogenetic profiles associated with selective serotonin reuptake inhibitors (SSRI)-induced behavioral disinhibition in children with Major depressive disorder (MDD), anxiety disorders…
- Conditions
- Obsessive-Compulsive Disorder, Anxiety Disorders, Major Depressive Disorder, Antidepressant Drug Adverse Reaction
- Trial name
- PGx-AID (NCT03953014)
- Where
- Canada
- Volunteers
- 120 people
- Sponsor
- University of Calgary
Tourette Syndrome, Obsessive Compulsive Disorder
Developmental Phenomenology of Obsessive Compulsive Disorder and Tourette Syndrome in Children and Adolescents
OBJECTIVES: I. Characterize the natural history, associated features, and severity of symptoms of obsessive compulsive disorder and Tourette syndrome in children and adolescents. II.
- Trial name
- NCT00004324
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- National Center for Research Resources (NCRR)
Obsessive Compulsive Disorder, Major Depressive Disorder
Integrating Pharmacogenomic Testing Into a Child Psychiatry Clinic
The purpose of this study is to examine the feasibility, acceptability, and utility of pharmacogenomic (PGX) testing (specifically for the cytochrome P450 2D6 and 2C19 genes) prior to initiating treatment with an antidepressant…
- Conditions
- Obsessive Compulsive Disorder, Major Depressive Disorder, Anxiety
- Trial name
- PGX (NCT02855580)
- Where
- United States
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- University of Florida
Depression, Obsessive-Compulsive Disorder
Pharmacogenetics in Primary Care Psychotropics
Pragmatic trial of pharmacogenetic testing at the time of prescription for a selective serotonin reuptake inhibitor, tricyclic antidepressant or atypical antipsychotic. Does real time intervention improve patient outcomes?
- Conditions
- Depression, Obsessive-Compulsive Disorder, Generalized Anxiety Disorder
- Trial name
- NCT03232502
- Testing
- Pharmacogenetic testing
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- University of Arizona
Hoarding Disorder, Hoarding
Rapid Non-Invasive Brain Stimulation for Hoarding Disorder
This study explores whether rapid non-invasive brain stimulation can help reduce hoarding disorder symptoms.
- Conditions
- Hoarding Disorder, Hoarding, Clutter
- Trial name
- TMS-HOLA (NCT06712914)
- Testing
- MagPro X100 by MagVenture
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Stanford University
Anorexia Nervosa
Identifying Networks Underlying Compulsivity in Anorexia Nervosa for Targeting With Neuromodulation
Transcranial Magnetic Stimulation (TMS) is approved by the Food and Drug Administration (FDA) for the treatment of refractory Major Depressive Disorder (MDD) and obsessive-compulsive disorder (OCD).
- Trial name
- NCT06138782
- Testing
- Repetitive Transcranial Magnetic Stimulation (rTMS)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of California, San Francisco
Aneurysms, Arteriovenous Malformations
Neurosurgical Outcome Network
The evaluation of neurosurgical outcomes varies from center to center, and the predictive factors that determine these outcomes are not fully known or shared.
- Conditions
- Aneurysms, Arteriovenous Malformations, Cavernomas, Skull Base Tumors
- Trial name
- NEON (NCT06724029)
- Where
- 27 sites in Italy
- Volunteers
- 4,500 people
- Sponsor
- Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta