Clinical trials: Obsessive Compulsive Disorders
Anxiety
Youth Mayo Clinic Anxiety Coach Pilot Study
This research study aims to test the feasibility and effectiveness of using the Mayo Clinic Anxiety Coach smartphone app as an addition to traditional therapy for the treatment of anxiety disorders in youth, particularly those…
- Trial name
- NCT02205177
- Testing
- Mayo Clinic Anxiety Coach
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Stephen Whiteside
Autism, Asperger's Syndrome
Exposure-Focused Family-Based CBT for Youth With ASD and Comorbid Anxiety
Autism spectrum disorders affect as many as 1 out of 88 children and are related to significant impairment in social, adaptive, and school functioning.
- Conditions
- Autism, Asperger's Syndrome, Pervasive Developmental Disorder Not Otherwise Specified, Generalized Anxiety Disorder
- Trial name
- NCT01919970
- Testing
- Cognitive Behavioral Therapy, Treatment as usual
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of South Florida
Obsessive-Compulsive Disorder, Generalized Anxiety Disorder
Memantine Treatment for Obsessive-compulsive Disorder and Generalized Anxiety Disorder
The objective of this study was to obtain preliminary open-label data on the efficacy and tolerability of memantine, an anti-glutamatergic medication with a unique pharmacodynamic profile, in individuals with OCD and individuals…
- Trial name
- NCT00674219
- Testing
- Memantine
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- University of California, Los Angeles
Obsessive-Compulsive Disorder
Dealing With Intrusive Thoughts in OCD - a Comparison of Detached Mindfulness and Cognitive Restructuring
The purpose of this study is to assess and compare the overall efficacy and differential effects of detached mindfulness and cognitive restructuring in the treatment of patients with obsessive-compulsive disorder.
- Trial name
- NCT03002753
- Testing
- detached mindfulness, cognitive restructuring
- Where
- Germany
- Volunteers
- 43 people
- Sponsor
- Christoph-Dornier-Stiftung für Klinische Psychologie
Obsessive Compulsive Disorder
Duloxetine for the Treatment of Obsessive Compulsive Disorder (OCD)
The purpose of this study is to assess the efficacy of Duloxetine in the treatment of obsessive compulsive disorder.
- Trial name
- FIJ-MC-1003 (NCT00464698)
- Testing
- Duloxetine
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Massachusetts General Hospital
Body Dysmorphic Disorder, Obsessive-compulsive Disorder
Oxytocin Administration in BDD and OCD
The purpose of the current study is to investigate the effect of an acute administration of intranasal oxytocin, relative to placebo, on social cognitive impairments among individuals with body dysmorphic disorder and…
- Trial name
- NCT02671266
- Testing
- Oxytocin
- Where
- United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Obsessive Compulsive Disorder, Trichotillomania
Developing Effective Response Inhibition Training for Symptom Relief in OCD and Trichotillomania
Obsessive-compulsive disorder (OCD) and its related disorders (e.g., trichotillomania) are characterized by the marked difficulty in inhibiting unwanted or inappropriate responses.
- Trial name
- NCT02059980
- Testing
- Response inhibition training
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- University of Wisconsin, Milwaukee
Major Depressive Disorder, Anxiety Disorder
Tapering Off Antidepressants
The purpose of this study is to compare two ways to stop taking an antidepressant medication and determine whether a faster or slower taper is better tolerated.
- Conditions
- Major Depressive Disorder, Anxiety Disorder, Obsessive Compulsive Disorder, Post-Traumatic Stress Disorder
- Trial name
- NCT02661828
- Testing
- Two-Week Antidepressant Taper Regimen, One-Week Antidepressant Taper Regimen
- Where
- 3 sites in United States
- Volunteers
- 2 people
- Sponsor
- Emory University
Obsessive-Compulsive Disorder
Transcranial Direct Current Stimulation Augmented Exposure and Response Prevention for Obsessive-Compulsive Disorder
This study is investigating whether combining noninvasive brain stimulation with behavior therapy can help to improve outcomes for obsessive-compulsive disorder (OCD).
- Trial name
- NCT02329587
- Testing
- ERP plus tDCS
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Butler Hospital
PANS, PANDAS
Antibiotic Treatment Trial for the PANDAS/PANS Phenotype
The purpose of this research study is to know if the antibiotic azithromycin, an antibiotic approved by the U.S. Food and Drug Administration (FDA) for treating infections, improves symptom severity in children with sudden and…
- Conditions
- PANS, PANDAS, Obsessive Compulsive Disorder (OCD)
- Trial name
- AZT (NCT01617083)
- Testing
- Azithromycin
- Where
- United States
- Volunteers
- 47 people
- Sponsor
- University of South Florida
Obsessive-compulsive Disorder
Stepped Care for Treating Obsessive-Compulsive Disorder
This study will determine the effectiveness and cost-effectiveness of a stepped-care treatment program for people with obsessive-compulsive disorder.
- Trial name
- NCT00316355
- Testing
- Traditional CBT, Stepped-Care CBT
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- Hartford Hospital
Obsessive-compulsive Disorder
D-cycloserine Augmentation of Cognitive Behavioral Therapy (CBT) for Pediatric Obsessive-compulsive Disorder (OCD)
The investigators are conducting a randomized double-blind placebo-controlled study to assess the efficacy of d-cycloserine augmentation of cognitive-behavioral therapy for the treatment of pediatric obsessive compulsive…
- Trial name
- NCT01411774
- Testing
- Cognitive-behavioral therapy, d-cycloserine
- Where
- 2 sites in United States
- Volunteers
- 142 people, healthy volunteers welcome
- Sponsor
- University of South Florida
Obsessive Compulsive Disorder
Intravenous Ketamine in the Treatment of Obsessive-Compulsive Disorder
Obsessive-Compulsive Disorder (OCD) is a chronic and disabling anxiety disorder and a leading cause of worldwide disability that presents a significant public health problem.
- Trial name
- IVKetamine (NCT01371110)
- Testing
- Ketamine, Midazolam
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Wayne Goodman MD
Obsessive Compulsive Disorder
A Phase 3 Study of Fluvoxamine (SME3110) in Pediatric/Adolescent Patients With Obsessive Compulsive Disorder
The objective of the first phase of this study is to evaluate the efficacy of fluvoxamine compared to placebo on change in total score of Japanese version of the Children's Yale-Brown Obsessive Compulsive Scale (JCY-BOCS) 10-item…
- Trial name
- NCT01933919
- Testing
- Fluvoxamine maleate
- Volunteers
- 38 people
- Sponsor
- AbbVie
Obsessive-Compulsive Disorder (OCD)
Open Label Trial of Rapastinel (Formerly GLYX-13) in Individuals With Obsessive-Compulsive Disorder
This research study tests whether GLYX-13 - an experimental drug that acts on a brain receptor called NMDA - can decrease symptoms of OCD within hours. This is not a treatment study.
- Trial name
- NCT02267629
- Testing
- Rapastinel (formerly GLYX-13)
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- New York State Psychiatric Institute
Obsessive-Compulsive Disorder
Memantine Augmentation in Treatment-Resistant Adults With Obsessive-Compulsive Disorder
Obsessive-compulsive disorder (OCD) is a common psychiatric illness that affects up to 2-3% of the population. People with OCD experience anxiety-provoking, intrusive thoughts, known as obsessions, and feel compelled to perform…
- Trial name
- NCT00956085
- Testing
- Memantine
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- New York State Psychiatric Institute
Obsessive-Compulsive Disorder
Memantine Augmentation in Obsessive-Compulsive Disorder
The purpose of this study is to determine whether memantine is safe and effective when used as an augmentation to standard treatment for Obsessive-Compulsive Disorder (OCD).
- Trial name
- NCT00264238
- Testing
- Memantine
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Stanford University
Obsessive-Compulsive Disorder
A Trial of Intranasal Ketamine for the Treatment of Obsessive-Compulsive Disorder
This study is being done to learn whether administration of intranasal (inhaled through the nose) ketamine reduces symptoms of obsessive-compulsive disorder (OCD). Ketamine has been approved by the U.S.
- Trial name
- NCT02234011
- Testing
- Ketamine
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Mclean Hospital
Obsessive-Compulsive Disorder
Randomized Controlled Trial of Intranasal Ketamine vs. Intranasal Midazolam in Individuals With OCD
Obsessive-compulsive disorder (OCD) is a common illness that causes significant distress and impairment. Currently, serotonin reuptake inhibitors (SRIs) are the only medications that are FDA-approved to treat OCD.
- Trial name
- NCT02206776
- Testing
- Intranasal Ketamine, Intranasal Midazolam
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- New York State Psychiatric Institute
Obsessive-Compulsive Disorder
Dextro-Amphetamine Versus Caffeine in Treatment-resistant OCD
The study hypothesis is that dextro-amphetamine (d-amphetamine) will be safe and effective when used to augment treatment for Obsessive-Compulsive Disorder (OCD), and that tolerance (loss of therapeutic effect) to the medication…
- Trial name
- NCT00363298
- Testing
- dextro-amphetamine
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Stanford University