Clinical trials: Obesity Associated Disorder
Early Puberty
the Association Between Obesity and Early Puberty
childhood obesity and early puberty are closely related, but existing reports usually focus on their relationship from the perspective of phenotype.
- Trial name
- NCT04317014
- Volunteers
- 628 people, healthy volunteers welcome
- Sponsor
- Shenzhen Center for Disease Control and Prevention
Obesity
Factors Associated With Obesity in Adult Women: Respiratory Exchange Ratio, Heart Rate Variation and Body Image
The prevalence of obesity all over the world has increased year by year, and how to effectively prevent and treat obesity has become an important health care issue.
- Trial name
- NCT04029532
- Testing
- Respiratory exchange ratio, Heart rate variability, Body composition
- Where
- Taiwan
- Volunteers
- 121 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
NAFLD, NASH
The European NAFLD Registry
The European NAFLD Registry is a prospectively recruited, observational study supporting the study of the clinical phenotype, natural history, disease outcomes and pathophysiology of Non-Alcoholic Fatty Liver Disease and…
- Conditions
- NAFLD, NASH, NASH - Nonalcoholic Steatohepatitis, Fibrosis, Liver
- Trial name
- NCT04442334
- Where
- 37 sites in Belgium, Finland and 10 more
- Volunteers
- 10,000 people
- Sponsor
- Newcastle University
Fatty Liver Disease
A Clinical Study of Ultrasound-derived Fat Fraction to Assess Metabolic Dysfunction-Associated Steatotic Liver Disease
Aims: To evaluate the diagnostic performance of ultrasound-derived fat fraction (UDFF) in assessing the degree of hepatic steatosis in an obese population, with liver biopsy as reference standard.
- Trial name
- NCT06487325
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Ma Zhe
Obesity, Diet Therapy
Predicting Weight Gain and Weight Loss Associated With Overeating or Fasting
This study will investigate how to better predict why some individuals gain or lose weight more easily than others. It will examine whether the increase in the amount of energy a body burns in 24 hours with overeating or the…
- Conditions
- Obesity, Diet Therapy, Weight Loss, Weight Gain
- Trial name
- NCT00687115
- Testing
- Weight Loss, Overfeeding, Overfeeding Low Pro
- Where
- United States
- Volunteers
- 83 people
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Obesity, Obstructive Sleep Apnea
Changes in Body Fat and Morphologic Characteristics Associated With OSA Resolution After Bariatric Surgery
Prospective study with inclusion of bariatric surgery candidates with diagnosed Obstructive Sleep Apnea and requiring treatment with Continuous Positive Air Pressure, aiming to evaluate at 2-6-12 months after bariatric surgery…
- Trial name
- NCT05315752
- Testing
- Bariatric surgery
- Where
- 2 sites in Belgium
- Volunteers
- 60 people
- Sponsor
- Centre Hospitalier Universitaire Saint Pierre
Obesity
Obesity in Children and Adolescents: Associated Risks and Early Intervention
The investigators hypothesize that Metformin decreases weight, normalizes lipid profile and increases insulin sensitivity; the study team hope to get better effect of weight decrease and metabolic processes repair in the…
- Trial name
- OCA (NCT01677923)
- Testing
- Metformin
- Where
- Lithuania
- Volunteers
- 182 people
- Sponsor
- Lithuanian University of Health Sciences
Liver Steatoses
Metabolic Dysfunction Associated Fatty Liver Disease in Long-Term Cholecystectomy Patients
The aim of this study was to examine the association between metabolic associated fatty liver disease (MAFLD) in participants who had undergone cholecystectomy and those who had not undergone cholecystectomy.
- Trial name
- NCT06443723
- Testing
- USG, blood tests, waist, hip, height and blood pressure measurements
- Where
- Turkey (Türkiye)
- Volunteers
- 149 people, healthy volunteers welcome
- Sponsor
- Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital
Neurodevelopmental Disorders, Irritability
AP Metabolism Transcriptomics
It is known from the literature that treatment with antipsychotic drugs (AP) induces, even before changes in blood chemistry parameters, changes in gene transcription that are evident at the level of peripheral blood mononuclear…
- Trial name
- NCT06814314
- Testing
- Transcriptomic investigation
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- IRCCS Eugenio Medea
Rheumatoid Arthritis, Ankylosing Spondylitis
PatientSpot Formerly Known as ArthritisPower
Patient Power is a patient research network and database (registry) to collect prospective information about demographics, self-reported diagnoses and medications, and willingness to participate in research from participants with…
- Conditions
- Rheumatoid Arthritis, Ankylosing Spondylitis, Fibromyalgia, Gout
- Trial name
- NCT03840928
- Where
- United States
- Volunteers
- 40,000 people, healthy volunteers welcome
- Sponsor
- Global Healthy Living Foundation
Metabolic Dysfunction-Associated Steatohepatitis (MASH), Obesity
Efficacy and Safety of CS0159 Combined With Semaglutide in MASH Patients With Obesity and T2DM
This is an exploratory study evaluating CS0159 in combination with Semaglutide in MASH patients with obesity and T2DM.
- Conditions
- Metabolic Dysfunction-Associated Steatohepatitis (MASH), Obesity, Diabetes Mellitus, Type 2
- Trial name
- NCT06492330
- Testing
- CS0159
- Where
- China
- Volunteers
- 62 people
- Sponsor
- Shanghai Jiao Tong University School of Medicine
Sepsis, Pre-Eclampsia
Establishment of an ELISA for the Recognition of Procalcitonin Variants in Patients With Hyperprocalcitonemia.
Procalcitonin is a protein consisting of 116 amino-acids which can rapidly rise under inflammatory conditions and sepsis. More than 20 years ago it has been shown that dipeptidylpeptidase-4 (DPP-4) cleaves procalcitonin from the…
- Conditions
- Sepsis, Pre-Eclampsia, Granulomatosis With Polyangiitis, Microscopic Polyangiitis
- Trial name
- NCT05703802
- Testing
- Procalcitonin-variants ELISA-Assay
- Where
- Germany
- Volunteers
- 30 people
- Sponsor
- University Hospital Muenster
Obesity
Dexmedetomidine to Treat Bariatric Surgery-associated Pain
Obesity represents one of the most important public health issues according to the World Health Organization and it has reached epidemic proportions globally.
- Trial name
- NCT02880540
- Testing
- Fentanyl, Morphine, Dexmedetomidine
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Janelle Vaughns
Obesity, Cardiovascular Risk Factor
Hipoenergetic Effect of Diet Associated or Not With the Consumption of Coconut Flour in Women With Overweight
This study aimed to evaluate the effect of weight loss with diet combined coconut flour consumption improvement weight loss and reduction in glucose, cholesterol in obese women.
- Trial name
- NCT02152111
- Testing
- Coconut flour, Diet
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Universidade Federal do Rio de Janeiro
Obesity
Changes in Sexual Function Following Bariatric Surgery
The main purposes of the study are to compare changes in sexual function, changes in sex hormones, and changes in body image and marital satisfaction at 12, 24, 36 and 48 months postoperatively in two groups: individuals who…
- Trial name
- NCT00670098
- Testing
- Bariatric surgery, lifestyle intervention (behavioral weight loss)
- Volunteers
- 207 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Binge Eating Disorder, Binge Eating Episodes
HALO-TRIAL: High, Medium And LOw Intensity Psychotherapy for Binge Eating Disorder
The HALO trial is designed as a four-armed, assessor-blinded, fidelity-monitored randomized clinical trial. The goal of this randomized controlled study is to investigate the effectiveness of four different psychotherapy programs…
- Conditions
- Binge Eating Disorder, Binge Eating Episodes, Binge Eating/Loss of Control Eating, Binge Eating Disorders
- Trial name
- HALO (NCT07698132)
- Testing
- Cognitive Behavioral Therapy Enhanced - Individual, Cognitive Behavioral Therapy Enhanced - Group, Cognitive Behavioral Therapy - Guided Self Help
- Where
- Denmark
- Volunteers
- 256 people
- Sponsor
- Herlev and Gentofte Hospital
Obesity, Type2diabetes
Susceptibility to Infectious Diseases in obEsity: an endocRine trAnslational socioLogic Evaluation, "SIDERALE"
Obesity is a life-threatening disease, defined by excessive fat accumulation that increases the risk of other diseases such as cardiovascular events, hypertension, diabetes and cancer.
- Conditions
- Obesity, Type2diabetes, Lipodystrophy, Infections
- Trial name
- SIDERALE2020 (NCT06236932)
- Testing
- Mediterranean diet, Melatonin supplementation
- Where
- 4 sites in Italy
- Volunteers
- 100 people
- Sponsor
- Federico II University
Periodontitis, Obesity
Investigation of Asprosin a Novel Adipokine in Periodontitis
Asprosin, a recently discovered glucogenic adipokine, is mainly synthesized by white adipose tissue and released during fasting. Appetite, glucose metabolism, insulin resistance, cell apoptosis, etc.
- Conditions
- Periodontitis, Obesity, Diabetes Mellitus
- Trial name
- NCT05449821
- Testing
- Serum and salivary samples will be collected. Asprosin levels will be determined by biochemical analysis
- Where
- Turkey (Türkiye)
- Volunteers
- 65 people
- Sponsor
- Ataturk University
Obesity, Metabolic Dysfunction-associated Steatotic Liver Disease
ELEVATE-LIVER: A Study to Test Whether Survodutide Helps Improve Heart Structure and Function in People With Overweight or Obesity and Fatty Liver Disease
This study is for adults aged 18 years and older who have a type of fatty liver disease called metabolic dysfunction-associated steatotic liver disease (MASLD).
- Trial name
- NCT07850063
- Testing
- Survodutide
- Where
- 25 sites in United States, China and 3 more
- Volunteers
- 600 people
- Sponsor
- Boehringer Ingelheim
Obstructive Sleep Apnea Syndrome, Obesity
Influence of nCPAP on Metabolic Consequences Associated With OSAS
Context: Obstructive sleep apnea syndrome (OSAS) is associated with cardiovascular morbidity. Recurrent episodes of occlusion of upper airways during sleep result in hormonal changes that may predispose to high cardiovascular…
- Trial name
- NCT00435643
- Testing
- nasal continuous positive airway pressure
- Where
- Brazil
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Federal University of São Paulo