Clinical trials: Obesity (BMI > 35) and Diabetes Mellitus
Diabetes Mellitus, Type 2
Laparoscopic Gastric Bypass for Type 2 Diabetes Mellitus With Body Mass Index (BMI) < 35
The aim of this study is to evaluate the effect of Roux-en-y gastric bypass (RYGB) in controlling diabetes in subjects with mild obesity (BMI 26-35).
- Trial name
- NCT00999050
- Testing
- Gastric bypass for diabetic patients <35 BMI
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Weill Medical College of Cornell University
Diabetes Mellitus, Metabolic Surgery
Metabolic Surgery; Gastric Bypass vs Sleeve Gastrectomy; Efects Over Type 2 DM With Bad Metabolic Control (MSO1CT)
The aim of the study is to compare the efficacy of laparoscopic gastric bypass versus vertical gastrectomy for the resolution of DM in patients with BMI 30-35.
- Conditions
- Diabetes Mellitus, Metabolic Surgery, Sleeve Gastrectomy, BPGY
- Trial name
- MSO1CT (NCT03891056)
- Testing
- metabolic surgery
- Where
- Spain
- Volunteers
- 40 people
- Sponsor
- Hospital Universitario Doctor Peset
Normal Healthy Volunteer, Safety After Oral Intake
A Research Study to Evaluate BLX-7006 in Healthy Adults
This study will test an oral medicine called BLX-7006, which acts like the hormone Glucagon-like Peptide-1 (GLP-1) to help control blood sugar and body weight. Current GLP-1 medicines are given by injection.
- Trial name
- NCT07140055
- Testing
- BLX-7006
- Where
- Australia
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Biolexis Therapeutics
Guidelines, Diabetes Mellitus Type 2
Adherence to Clinical Guidelines for Management of Patients With Type 2 Diabetes Mellitus and Obesity
Observational study in physicians regarding their adherence to clinical guidelines (by American Diabetes Association 2025) for the management of type 2 diabetes mellitus and obesity via questionnaire
- Conditions
- Guidelines, Diabetes Mellitus Type 2, Obesity Type 2 Diabetes Mellitus, Obesity (BMI > 35) and Diabetes Mellitus
- Trial name
- NCT07839546
- Testing
- Questionnaire regarding the adherence to American Diabetes Association
- Where
- Greece
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Aristotle University Of Thessaloniki
Glucose Metabolism, Lipid Metabolism
Effects of 10-gram Collagen Protein Hydrolysate on Cardiometabolic Health
The effects of a 10g/day collagen hydrolysate for a period of 4 weeks on glycemic control and cardiovascular health in a parallel design study using overweight/ obese men and women who are likely to have a disturbed lipid and…
- Trial name
- NCT05282641
- Testing
- 10 g of collagen hydrolysate
- Where
- Netherlands
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Obesity, Morbid, Obesity (BMI > 35) and Diabetes Mellitus
Pilot Study of an Intervention Involving Cognitive Training and tDCS in Morbidly Obese Subjects
The study aims to: 1) investigate the effects of cognitive training (CT) and combined CT and transcranial direct current stimulation (tDCS) on food intake and 2) to further understand its neuropsychological and neurophysiological…
- Conditions
- Obesity, Morbid, Obesity (BMI > 35) and Diabetes Mellitus, Obesity (BMI > 35) and High Blood Pressure, Obesity (BMI > 35) and Dyslipemia
- Trial name
- NCT03943979
- Testing
- Cognitive Training, transcranial Direct-Current Stimulation (tDCS)
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Parc de Salut Mar
Obesity (BMI > 35) and Diabetes Mellitus, Obesity (BMI > 35) and Dyslipemia
Preoperative Optimization With Tirzepatide, Ketogenic Diet, or Standard Care Before One Anastomosis Gastric Bypass Surgery
This study compares three preoperative strategies before one anastomosis gastric bypass(OAGB) for severe obesity. Participants will be assigned to receive either tirzepatide medication for 60 days, a ketogenic diet for 4 weeks…
- Conditions
- Obesity (BMI > 35) and Diabetes Mellitus, Obesity (BMI > 35) and Dyslipemia, Obesity (BMI > 35) and High Blood Pressure
- Trial name
- OPTI-OAGB (NCT07622992)
- Where
- Italy
- Volunteers
- 96 people
- Sponsor
- Mario Musella MD
Diabetes Mellitus, Non-Insulin-Dependent
Effect of Laparoscopic Roux-en-Y Gastric Bypass Surgery on Non-severe Obesity With Type 2 Diabetes Mellitus
The effect of roux-en-Y gastric bypass(RYGB) on patients with type 2 diabetes mellitus(T2DM) and a body mass index(BMI)>35kg/m2 is clear.
- Trial name
- NCT02091323
- Testing
- gastric bypass surgery
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Guangzhou General Hospital of Guangzhou Military Command
Obesity (BMI > 35), Obesity (BMI > 35) and Diabetes Mellitus
HUGO-SLEEVE: Evaluating the Feasibility of Robotic Sleeve Gastrectomy With a New Platform
Severe obesity is a chronic condition that can lead to a range of serious health problems. One common treatment option is sleeve gastrectomy, a weight-loss operation in which the size of the stomach is reduced.
- Conditions
- Obesity (BMI > 35), Obesity (BMI > 35) and Diabetes Mellitus, Obesity (BMI > 35) and Dyslipemia, Obesity (BMI > 35) and High Blood Pressure
- Trial name
- NCT07884994
- Testing
- Sleeve Gastrectomy using Hugo RAS platform
- Where
- Germany
- Volunteers
- 50 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Obesity, Type 2 Diabetes
Longitudinal Cohort Study Comparing 2 Surgical Techniques in Patients With Class 3 Obesity and Type 2 Diabetes
Wight loss surgery provides good glycemic control in type 2 diabetes. The technique of "Roux-en-Y gastric bypass" is more effective than the "Adjustable Gastric Band" on weight loss.
- Trial name
- OBEDIAB (NCT00688974)
- Testing
- Roux-en-Y gastric bypass, Adjustable gastric band
- Where
- France
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- University Hospital, Lille
Obesity, Myelomeningocele
Extended Criteria For Fetal Myelomeningocele Repair
The purpose of this study is to offer pre-natal Myelomeningocele (MMC) repair surgery to pregnant women with one of the former surgery exclusion factors A BMI of 35-40 kg/m2 Diabetes; patients will require good glycemic control…
- Conditions
- Obesity, Myelomeningocele, Pregnancy, Diabetes Mellitus in Pregnancy
- Trial name
- NCT02664207
- Testing
- Open Fetal Repair of Myelomeningocele
- Where
- 2 sites in United States
- Volunteers
- 12 people
- Sponsor
- The University of Texas Health Science Center, Houston