Clinical trials: Obesity, Abdominal
Insulin Resistance, Obesity
Metformin Effect on Brain Function in Insulin Resistant Elderly People
Alzheimer's disease (AD) and other forms of dementia are rapidly increasing with the aging of the population, and show a clear preponderance among people with insulin resistance.
- Conditions
- Insulin Resistance, Obesity, Obesity, Abdominal
- Trial name
- NCT03733132
- Testing
- Metformin Hydrochloride
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Mitochondrial Respiratory Chain Deficiencies
Abdominal Adiposity and Muscle Mitochondrial Functions
Numerous studies have demonstrated that excess perivisceral adipose tissue is associated with metabolic diseases such as insulin resistance.
- Trial name
- Mithycal (NCT00446745)
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement
Obesity
Growth Hormone, Cardiovascular Risk, and Visceral Adiposity
This study will compare growth hormone levels and cardiovascular risk markers in normal weight and overweight women and men. In women and men with increased abdominal weight, growth hormone (GH) versus placebo will be…
- Trial name
- NCT00131378
- Testing
- Nutropin AQ growth hormone
- Where
- United States
- Volunteers
- 142 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Cardio-metabolic Health
Peer-modeled Intervention
The goal of this clinical trial is to learn about the effects of a peer-led behavioural change intervention on the cardio-metabolic health of women aged 18 to 49 years.
- Trial name
- NCT07476716
- Testing
- A peer-modelled behavioural change intervention
- Where
- Uganda
- Volunteers
- 157 people
- Sponsor
- KU Leuven
Obesity, Overweight
Abdominal and Core Exercises on Respiratory Functions in Obese and Overweight Women (COREBREATH)
This study aims to examine the effects of an 8-week Pilates-based exercise program on breathing functions in overweight and obese women (BMI ≥ 25).
- Conditions
- Obesity, Overweight, Pulmonary Disease, Muscle Weakness
- Trial name
- COREBREATH (NCT07103499)
- Testing
- Pilates-Based Core and Breathing Exercise Program
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Ondokuz Mayıs University
Adults, Overweight , Obesity
High Phenolic Olive Oil for Enhancing Metabolic Health: a Randomized-controlled Trial in Patients With cEntral Obesity (HOPE)
Olive oil is a fundamental component of the Mediterranean diet and a major source of monounsaturated fatty acids with well-established cardioprotective properties.
- Conditions
- Adults, Overweight , Obesity, Metabolic Abnormalities, Consented to Participate in the Trial and Signed an ICF
- Trial name
- HOPE (NCT07445503)
- Testing
- Low phenolic olive oil, High phenolic olive oil
- Where
- Greece
- Volunteers
- 80 people
- Sponsor
- University of Peloponnese
Psoriasis, Arthritic Psoriasis
Evaluation of Adipokines and Fat Tissue in Psoriasis and Psoriatic Arthritis
Body composition analysis and especially body fat distribution in regions of interest (android and in particular intra-abdominal region) provides some information on the risk of cardiovascular disease.
- Trial name
- ADIPSO (NCT02849795)
- Testing
- bone densitometry, questionnaires, biological analyses
- Where
- France
- Volunteers
- 199 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Central Obesity, Ventilatory Function
Effect of Thoracic Mobilization in People With Central Obesity
The goal of this clinical trial is to learn whether Mulligan thoracic mobilization in extension improves ventilatory functions and chest wall expansion in adults with central obesity.
- Trial name
- NCT07718178
- Testing
- Mulligan Thoracic Mobilization, low carbohydrate, Aerobic Exercise
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
Central Obesity, Time Restricted Eating
Impact of Chronotype-Based Time-Restricted Eating on Visceral Fat and Metabolic Health in Physically Inactive Adults With Central Obesity
Time-restricted eating (TRE) has gained attention as a promising dietary strategy for enhancing body composition and metabolic health.
- Trial name
- NCT07062315
- Testing
- Chronotype-matched time-restricted eating, Chronotype-unmatched time-restricted eating
- Where
- China
- Volunteers
- 90 people
- Sponsor
- Chinese University of Hong Kong
Obesity
Epigenetic Regulation of Human Adipose Tissue Distribution
The purpose of this study is to collect data to help researchers better understand the different ways that women or men store fat (apple shape versus pear shape).
- Trial name
- Eiffel 2 (NCT02728635)
- Testing
- Dual-energy X-ray absorptiometry (DEXA)/ Magnetic resonance imaging (MRI) and Magnetic resonance spectroscopy (MRS), Adipose tissue biopsies, FSIGTT/ RMR
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- AdventHealth Translational Research Institute
Abdominal Obesity, Obesity
Suture Length Effects in Acupoint Implantation for Abdominal Obesity
Obesity is a metabolic disorder and has become a global health issue with a steadily increasing prevalence. According to the Health Promotion Administration's statistical report, the overweight and obesity rate among adults in…
- Trial name
- NCT07125716
- Testing
- 1 inch, 0.5 inch
- Where
- Taiwan
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Cardiovascular Diseases, Obesity, Visceral
Extreme Exercise and Energy Expenditure (4E) Study
The goal of this clinical trial is to provide evidence, through an extreme exercise prescription (1,144 km of road cycling on seven consecutive days), that weight loss is not the appropriate outcome to evaluate the effects of…
- Conditions
- Cardiovascular Diseases, Obesity, Visceral, Liver Fat, Metabolic Syndrome
- Trial name
- NCT05895916
- Testing
- High-volume road cycling
- Where
- Canada
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Institut universitaire de cardiologie et de pneumologie de Québec, University Laval
Upper Body Obesity
Exercise-stimulated Muscle Glucose Uptake in Upper Body Obesity
The purpose of this study is to provide the first integrated examination of the interaction between muscle insulin action and exercise-stimulated muscle glucose uptake in obesity from the whole body to the cellular/molecular…
- Trial name
- NCT04532814
- Testing
- Exercise
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Obesity, Obesity, Abdominal
Effect of Balanced Hypocaloric Diet Associated With Supplementation of Eggplant Meal in the Remission of Cardiovascular Risk Factors
Cardiovascular diseases (CVD) prevail as the main cause of death in developed and developing countries and are among the most frequent causes of disabilities in Brazil and in the world.
- Trial name
- NCT01622309
- Testing
- eggplant meal, cassava meal
- Where
- Brazil
- Volunteers
- 363 people
- Sponsor
- Universidade Federal do Rio de Janeiro
Abdominal Muscles Strength, Abdominal Muscles Endurance
Combined Effects of Dead Bug Exercise and Double Straight Leg Raises Versus Conventional Physical Therapy Exercise on Core Stability and Waist Circumference in Healthy Young Individuals
Increased sedantry lifestyle has caused a decrese in core stability. Moreover alongwith sedantry lifestyle unhealthy eating habits have also increased causing an increase in abdominal adiposity and waist circumference.
- Conditions
- Abdominal Muscles Strength, Abdominal Muscles Endurance, Abdominal Muscles Flexibility, Waist Circumference
- Trial name
- NCT07467044
- Testing
- Combination of Dead Bug Exercise and Double Straight Leg Raises, Abdominal stretches
- Where
- Pakistan
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Health Sciences Lahore
Obesity, Obesity, Abdominal
Immunometabolic Effects of Non-drug Strategies in the Clinical Management of Obesity: Translational Study
Forty women aged between 18 and 75 years-old with a BMI> 30kg/m2 are recruited to participate in the evaluation of their medical management.
- Conditions
- Obesity, Obesity, Abdominal, Obesity, Visceral, Female
- Trial name
- PPAR-NAPAS (NCT04436419)
- Testing
- Alpha lipoic acid (plus full hospitalization)
- Where
- France
- Volunteers
- 40 people
- Sponsor
- Fauqué
Obesity, Obesity, Morbid
Endoscopic Metabolic and Bariatric Therapies
This is a prospective collection of data from adult patients who have had an endoscopic metabolic and bariatric endoscopy procedure (EMBT) for primary or revision surgical procedures for obesity.
- Conditions
- Obesity, Obesity, Morbid, Obesity Associated Disorder, Bariatric Surgery Candidate
- Trial name
- EMBTs (NCT05725967)
- Testing
- Primary Obesity Endoscopic Procedures, Endoscopic Revision of Bariatric Surgical Procedures, Bariatric Surgery Procedures
- Where
- United States
- Volunteers
- 5,000 people
- Sponsor
- Christopher C. Thompson, MD, MSc
Postmenopausal Women
Effect of Electroacupuncture on Central Obesity and Fatty Liver in Postmenopausal Women
The aim of this study is to determine the effect of electroacupuncture on central obesity and fatty liver in postmenopausal women.
- Trial name
- NCT07437001
- Testing
- Medical treatment, Hypocaloric diet, Electroacupuncture
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
Non-Alcoholic Fatty Liver Disease, Central Obesity
12-Month Once-a-week HIIT Improves Body Adiposity and Liver Fat
Obesity and non-alcoholic fatty liver disease (NAFLD) are two related growing epidemics that are becoming pressing public health concerns.
- Trial name
- NCT03912272
- Testing
- High-intensity Interval Training, Usual Care Control
- Where
- Hong Kong
- Volunteers
- 160 people
- Sponsor
- The University of Hong Kong
Obese Patients, Hypothalamic Neoplasms
KETO-TUMOR: a Study on Brain Tumors and Central Obesity
Hypothalamic-chiasmatic tumours account for 5-10% of CNS tumours in children and can compromise hypothalamic function, causing alterations in energy balance and weight gain.
- Trial name
- NCT07396896
- Testing
- Dietary intervention
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- Meyer Children's Hospital IRCCS