Clinical trials: OSA - Obstructive Sleep Apnea
Stroke, Sleep Apnea
Telemedicine Monitoring of Sleep Apnea in Stroke
Study Objectives: Meta-analyses report a high prevalence of moderate to severe sleep apnea of more than 50% in stroke patients, with adherence rates for CPAP therapy of only 30%.
- Trial name
- HOPES (NCT02748681)
- Testing
- Auto CPAP AirSense™ 10(Resmed)
- Where
- Austria
- Volunteers
- 34 people
- Sponsor
- Neurologisches Rehabiliationszentrum Rosenhügel
Obstructive Sleep Apnoea, Obesity
Lifestyle Intervention in Obstructive Sleep Apnoea
Obstructive sleep apnoea/hypopnoea syndrome (OSAHS) is a common disorder characterised by interrupted breathing while sleeping. It is associated with cardiovascular problems such as high blood pressure, heart attack and stroke.
- Trial name
- NCT01546792
- Testing
- Combined lifestyle intervention
- Where
- 2 sites in United Kingdom
- Volunteers
- 60 people
- Sponsor
- Sheffield Teaching Hospitals NHS Foundation Trust
Sleep Apnea
Cardiac Dysfunction in Obstructive Sleep Apnea Patients: Prevalence of and Effect of nCPAP
The aim of this study is to clarify the influence of obstructive sleep apnea syndrome on left ventricular function using echocardiographic parameters including the myocardial performance index (Tei-index), and to determine the…
- Trial name
- NCT00503945
- Testing
- Nasal continuous positive airway pressure (nCPAP)
- Where
- Japan
- Volunteers
- 27 people
- Sponsor
- Nagasaki University
Obstructive Sleep Apnea
Testing Settings of NovaResp's cMAP® Software During Home PAP Therapy
The goal of this clinical trial is to identify which settings of proactive therapy work best in OSA patients who regularly adhere to PAP therapy at home.
- Trial name
- NCT07898254
- Testing
- Dynamic cMAP, Direct cMAP
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- NovaResp Technologies Inc
Syndrome of Obstructive Sleep Apnea and Hypopneas
Mandibular Advancement Devices Tali® in Patients With Syndrome of Obstructive Sleep Apnea and Hypopneas
The main objective is to evaluate middle term compliance (≥ 2 years) of the Mandibular Advancement Devices Tali® in patients with Syndrome of Obstructive Sleep Apnea and Hypopneas.
- Trial name
- NCT02878629
- Testing
- Mandibular Advancement Devices
- Where
- France
- Volunteers
- 254 people
- Sponsor
- ONIRIS
Sleep Apnea
Effects of Upper Airway Muscle Training on Obstructive Sleep Apnea Severity
The purpose of this study is to evaluate the effect of Asate Silent Sleep Training on obstructive sleep apnea (OSA) severity in patients with mild to moderate OSA.
- Trial name
- NCT04053153
- Testing
- Exercise equipment (a musical instrument that is based on the Medical Didgeridoo)
- Sponsor
- Stanford University
Obstructive Sleep Apnea, End Stage Renal Disease
Prognostic Impact of Sleep Apnea on Cardiovascular Morbidity and Mortality, in End Stage Renal Disease Patients
The purpose of this study is to prospectively evaluate the impact of sleep apnea on the cardiovascular morbidity and mortality of patients with end-stage renal disease.
- Trial name
- SASinHD_003 (NCT02073305)
- Testing
- No Sleep Apnea, Sleep Apnea - untreated, Sleep Apnea - treated
- Where
- Switzerland
- Volunteers
- 200 people
- Sponsor
- Centre Hospitalier Universitaire Vaudois
Obstructive Sleep Apnea
Effect of Interscalene Block on Obstructive Sleep Apnea in Shoulder Surgery Patients
Obstructive Sleep Apnea (OSA) is when a person stops breathing repeatedly during sleep. Breathing stops because the airway collapses and prevents air from getting into the lungs.This airway closure results in a decrease in the…
- Trial name
- NCT02034370
- Testing
- Lung-function spirometry test, Overnight sleep test
- Where
- 2 sites in United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Michigan
Obstructive Sleep Apnea
Novel physIologiC prEdictors of Positive Airway Pressure Effectiveness
Millions of Americans suffer from high blood pressure, diabetes, strokes and motor vehicle accidents due to ineffective treatment of obstructive sleep apnea (OSA).
- Trial name
- NICEPAP (NCT05067088)
- Testing
- CPAP (all patients receive CPAP as part of routine clinical care)
- Where
- United States
- Volunteers
- 262 people
- Sponsor
- Yale University
Early Onset Alzheimer Disease, Alzheimer Disease
Sleep Apnea in Early to Mid-Stage Alzheimer's Disease
Obstructive sleep apnea (OSA) is much more common in the elderly than in the young; the latest studies show prevalence between 45% and 62% in individuals over 60.
- Conditions
- Early Onset Alzheimer Disease, Alzheimer Disease, Obstructive Sleep Apnea Syndromes
- Trial name
- AZAP (NCT01400542)
- Testing
- CPAP Treatment, No treatment
- Where
- France
- Volunteers
- 22 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Obstructive Sleep Apnea
Optiflow THRIVE for Delivery of Oxygen to Patients During Total Intravenous Anesthesia While Undergoing Radiology Procedures
This trial studies how well Optiflow THRIVE works in delivering oxygen to patients during total intravenous anesthesia while undergoing radiology procedures.
- Trial name
- NCT04171037
- Testing
- Oxygen Therapy, Questionnaire Administration, Optiflow THRIVE
- Where
- United States
- Volunteers
- 108 people
- Sponsor
- M.D. Anderson Cancer Center
Sleep Apnea, Obstructive, Obesity Hypoventilation Syndrome
Treatment for Obstructive Sleep Apnea Hypopnea Syndrome and Obesity Hypoventilation Syndrome (OHS)
Sleep Apnea Hypopnea Syndrome (OSAHS), is common in patients with OHS, compared to single Obesity Hypoventilation Syndrome (OHS) or OSAHS ,patients with both of them are more susceptible to have serious hypoxia and carbon dioxide…
- Trial name
- NCT01553227
- Testing
- ventilator
- Where
- China
- Volunteers
- 24 people
- Sponsor
- Nanjing Medical University
Obstructive Sleep Apnea of Adult
Acceptable Pressure Range for Continuous Positive Airway Pressure(CPAP) Treatment
Compliance of continuous positive airway pressure （CPAP） derived from auto-titration is similar to that derived from manual titration, although pressure derived from the former was usually 2-5 cmH2O higher than the latter.
- Trial name
- NCT04925466
- Testing
- CPAP at pressure of 10 cmH2O, CPAP at minimal effective pressure
- Where
- China
- Volunteers
- 40 people
- Sponsor
- State Key Laboratory of Respiratory Disease
OSA - Obstructive Sleep Apnea, Cognitive Functions
Cognitive Function in Obstructive Sleep Apnea
Obstructive sleep apnea (OSA) is the most common sleep-related breathing disorder and has been increasingly recognized as a contributor to cognitive decline and a potential risk factor for neurodegeneration.
- Trial name
- CUFM1DN (NCT07364318)
- Where
- Slovakia
- Volunteers
- 30 people
- Sponsor
- Comenius University
Obstructive Sleep Apnea
Measurement of Critical Closing Pressure (Pcrit) During Drug-Induced Sleep Endoscopy (DISE)
This study intends to test the feasibility of measurement of the critical closing pressure (Pcrit) during drug-induced sleep endoscopy (DISE) for use in future studies, which are aimed at finding an alternative method for patient…
- Trial name
- Pcrit-DISE (NCT04232410)
- Testing
- Drug induced sleep endoscopy, Measurement of critical closing pressure of the uppper airway
- Where
- Belgium
- Volunteers
- 13 people
- Sponsor
- University Hospital, Antwerp
Obstructive Sleep Apnea, Sleep
Impact of Exogenous Ketones on Sleep Disruption in Vulnerable Populations
Obstructive Sleep Apnea (OSA) is a common medical disorder that is associated with reduced quality of life and higher risk of cardiovascular disease. Treatments for OSA and limited and not well tolerated.
- Trial name
- KETO-SLEEP 1 (NCT06655649)
- Testing
- Ketone-IQ (1,3 Butanediol)
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Johns Hopkins University
Sleep Apnea, Heart Failure
Diagnosis and Treatment of Sleep Apnea in the Acute Exacerbation of Heart Failure
Congestive heart failure affects 2.3 percent of the population (approximately 4,900,000) with an incidence of 10 per 1,000 of the population after the age of 65 (1).
- Trial name
- NCT00701038
- Testing
- auto adjusting bi-level positive airway pressure device
- Volunteers
- 54 people
- Sponsor
- Rami Khayat
Osa Syndrome
Psychological Aspects in OSA
The research project consists of an observational study. Obstructive Sleep Apnea (OSA) is a condition characterized by recurrent episodes of upper airway collapse during sleep, leading to decreased blood oxygen levels and…
- Trial name
- PSICOSA (NCT06292325)
- Testing
- Continuous Positive Airway Pressure (CPAP)
- Where
- Italy
- Volunteers
- 246 people
- Sponsor
- Fondazione Don Carlo Gnocchi ETS
Osa Syndrome
Effects of Exercise on Sleep Quality in Patients With Obstructive Sleep Apnea Syndrome
the investigators aim in this study is to investigate the effects of aerobic and oropharyngeal exercises on sleep quality in patients with Obstructive Sleep Apnea Syndrome (OSAS).
- Trial name
- NCT06006520
- Testing
- control, oro-granary exercises., aerobic exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Uskudar University
Obstructive Sleep Apnea
Actigraphy Sleep Parameters in Obstructive Sleep Apnea Patient's
Those patient's that come to the sleep unit and that accept to participate in the study will undergo a polysomnography with the extra of an actigraphy placed in their no dominant arm wrist.
- Trial name
- NCT03060915
- Testing
- Polysomnography, Actigraphy
- Where
- Spain
- Volunteers
- 106 people
- Sponsor
- Hospital Clinic of Barcelona