Clinical trials: Nutrition Disorder
Obesity
Craving and Lifestyle Management Through Mindfulness Pilot Study
The purpose of this study is to determine whether an innovative program that combines mindfulness-based stress reduction and mindful eating practices with diet and exercise guidelines (CALMM+ intervention) will lead to greater…
- Trial name
- CALMM (NCT00643344)
- Testing
- Craving and Lifestyle Management through Mindfulness(CALMM+)
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Exercise, Physical Activity
The Active by Choice Today (ACT) Trial to Increase Physical Activity
The increasing prevalence of obesity in U.S. children and adolescents is a major health threat to our society, especially among minority and low social economic status (SES) populations.
- Conditions
- Exercise, Physical Activity, Obesity
- Trial name
- ACT (NCT01028144)
- Testing
- Physical Activity Program, General Health Program
- Where
- United States
- Volunteers
- 1,422 people, healthy volunteers welcome
- Sponsor
- University of South Carolina
Sleep Apnea, Obesity
Sleep Apnea in Pregnancy Screening Study
Obstructive sleep apnea is known to be a significant source of morbidity in the general population. It has been proposed to be associated with the development of preeclampsia and fetal growth restriction.
- Trial name
- SAPSS (NCT01585844)
- Where
- United States
- Volunteers
- 182 people, healthy volunteers welcome
- Sponsor
- MetroHealth Medical Center
Obesity
Healthy In-Store Marketing Study
Using a cluster randomized controlled design, this study will evaluate effects of in-store healthy food marketing strategies on sales and purchase of specific healthier items in six product categories (milk, frozen entrees…
- Trial name
- NCT02499211
- Testing
- Intervention stores
- Where
- United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Non-diabetec Obesity, Obesity (Disorder)
Weekly GLP-1 Receptor Agonists in Obese Individuals Without Diabetes
This randomized controlled trial evaluates the efficacy of three weekly GLP-1 receptor agonists (dulaglutide, semaglutide, and tirzepatide) in non-diabetic obese adults.
- Trial name
- NCT07834398
- Testing
- Dulaglutide, Semagludtide, Tirzepatide
- Where
- Saudi Arabia
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Weight Management, Cardiovascular (CV) Risk
Feasibility, Acceptability, and Validation of a User-friendly Diet Quality Tool in Adults From Ambulatory Nutrition Clinics
The study design for Perceptions and Learning About a Diet Tool (PLATE) was a prospective online dietary intake survey in adults engaged in ambulatory nutrition counseling.
- Conditions
- Weight Management, Cardiovascular (CV) Risk, Metabolic and Nutritional Disorders
- Trial name
- PLATE (NCT07109011)
- Where
- United States
- Volunteers
- 122 people
- Sponsor
- University of Pennsylvania
Acute Cardiovascular Disease
AI-POD Clinical Validation Study for Obese Patients
The study is aimed at patients who suffer from severe obesity and receive a computerised tomography (CT) scan of the heart. A total of 1200 patients across Europe are to take part in the study.
- Trial name
- AI-POD (NCT06595134)
- Testing
- Non Interventional
- Where
- 6 sites in Austria, Belgium and 3 more
- Volunteers
- 1,200 people
- Sponsor
- University Hospital, Bonn
Obesity, Overweight
Home Self-administration of Maridebart Cafraglutide With Autoinjector in Adults Living With Obesity or Overweight
The main objective of this study is to assess participants' ability to self-administer subcutaneous doses of maridebart cafraglutide at home using an autoinjector device.
- Trial name
- MARITIME-PEN (NCT07871409)
- Testing
- Maridebart cafraglutide, Autoinjector
- Where
- United States
- Volunteers
- 230 people
- Sponsor
- Amgen
Chronic Fatigue Syndrome
A Complex Intervention for Chronically Fatigued Lymphoma Survivors
The present study is a randomized controlled trial (RCT) with an overall objective to examine the effect of an interdisciplinary complex intervention on the level of fatigue in lymphoma survivors with chronic fatigue.
- Trial name
- NCT05130099
- Testing
- Interdisciplinary complex intervention
- Where
- Norway
- Volunteers
- 150 people
- Sponsor
- Oslo University Hospital
Obesity & Overweight, Energy Expenditure
Metabolic and Nutritional Responses to Acute High-intensity Interval Exercise Performed Under Hypoxic vs. Normoxic Conditions at Matched External Workload in Adults With Overweight and Obesity.
Obesity management involves lifestyle and dietary measures that include appropriate nutrition and increased physical activity (PA).
- Conditions
- Obesity & Overweight, Energy Expenditure, Substrate Oxidation
- Trial name
- HYPOXHIIT (NCT07814599)
- Testing
- HIIE - Normoxia, HIIE - Hypoxia
- Where
- France
- Volunteers
- 18 people
- Sponsor
- Laboratoire des Adaptations Métaboliques à l'Exercice en conditions Physiologiques et Pathologiques
Obesity, Overweight
A Study of Tirzepatide (LY3298176) in Chinese Participants Without Type 2 Diabetes Who Have Obesity or Overweight (SURMOUNT-CN)
This is a study of tirzepatide in Chinese participants without Type 2 Diabetes who have obesity or overweight. The main purpose is to learn more about how tirzepatide affects body weight.
- Conditions
- Obesity, Overweight, Metabolism and Nutrition Disorder
- Trial name
- SURMOUNT-CN (NCT05024032)
- Testing
- Tirzepatide
- Where
- 29 sites in China
- Volunteers
- 210 people
- Sponsor
- Eli Lilly and Company
Hepatitis
Treating Nonalcoholic Steatohepatitis (NASH) With Metformin
Nonalcoholic Steatohepatitis (NASH) is associated with progressive liver disease, fibrosis, and cirrhosis. Although the cause of NASH is unknown, it is often associated with obesity, type 2 diabetes, and insulin resistance.
- Trial name
- NCT00063232
- Testing
- Metformin
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Overweight
Probiotics for Weight Loss
This study will investigate a compound of probiotics and prebiotics in females and males with overweight with the aim to evaluate the effect on weight and metabolic markers.
- Trial name
- NCT04897698
- Testing
- LB001
- Where
- Sweden
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Obesity
Effect of Ghrelin on Glucose Metabolism After Bariatric Surgery
The purpose of this study is to determine if the altered nutrient exposure to the GI tract after bariatric surgery reveals a negative incretin effect of ghrelin.
- Trial name
- NCT02953587
- Testing
- Oral Glucose Tolerance Test (OGTT), Human Ghrelin, Saline
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Vanderbilt University Medical Center
Obesity
Pharmacokinetics of Dexmedetomidine in Morbid Obesity
Dexmedetomidine hydrochloride ,a relatively new drug in Chinais ,is a highly selective, potent a2-adrenoceptor agonist with significant analgesic, sedative and anxiolytic effects.
- Trial name
- NCT01864187
- Testing
- Dexmedetomidine
- Where
- China
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Guangzhou General Hospital of Guangzhou Military Command
Overweight, Obesity
The Effects of Exercise Snacks on Endothelial Function and Body Composition in Overweight Individuals
This randomized controlled trial investigates the effects of two types of stair-climbing exercise snacks versus moderate-intensity continuous training on vascular health, body composition, and blood lipids in overweight or obese…
- Trial name
- NCT07558421
- Testing
- Short-term stair climbing exercise snack group, Long-duration stair climbing exercise snack group, Moderate-intensity continuous exercise（MICT）
- Volunteers
- 60 people
- Sponsor
- Weifang Medical University
Obesity, Overweight
Environmental and Acceptance-Based Innovations for Weight Loss Maintenance
The major goal of this project is to evaluate an innovative approach to obesity involving modification of the home environment. The project also will evaluate if home environment modification is more effective when supplemented…
- Conditions
- Obesity, Overweight, Weight Loss
- Trial name
- ENACT (NCT01858714)
- Testing
- Behavior Therapy for Weight Loss, Behavior Therapy + Environment, Acceptance-based Behavior Therapy + Environment
- Where
- United States
- Volunteers
- 238 people
- Sponsor
- Drexel University
Obesity, Sarcopenia
Biological Effects of Weight Loss In Older, Obese Women
Obesity and sedentary lifestyle are associated with physical impairments and biological changes in older adults. Weight loss combined with exercise may reduce inflammation and may improve physical functioning in older adults who…
- Trial name
- WL+E (NCT01032733)
- Testing
- Lifestyle Counseling, Educational Control
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- University of Florida
Obesity
Pharmacokinetics of Dexamethasone in COVID-19 Obese Patients
In this regard, the present research project aims to compare dexamethasone PK in normal-weight versus obese patients treated for COVID-19.
- Trial name
- CoDEX (NCT04996784)
- Testing
- Capillary blood sampling
- Where
- Switzerland
- Volunteers
- 30 people
- Sponsor
- Jules Desmeules
Inflammatory Bowel Diseases
Preoperative Oral ImmunoNuTrition to Improve Surgical Outcomes for IBD Patients (PINT)
The central focus of this trial is to understand the effectiveness of Preoperative Immunonutrition (PINT) in improving surgical outcomes for patients with inflammatory bowel disease (IBD).
- Trial name
- PINT (NCT03333148)
- Testing
- Nestle IMPACT Immunonutrition, Arm B- Standard of Care
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham