Clinical trials: Nutrition
Kidney Transplantation
Change of Body Composition After Kidney Transplantation in Korea
The graft survival in kidney transplantation has been improving after the introduction of new immunosuppressive agents. Therefore, other complications after transplantation are concerned; one of those is obesity.
- Trial name
- NCT01157884
- Where
- South Korea
- Volunteers
- 50 people
- Sponsor
- Seoul National University Hospital
Vitamin D Deficiency, 25-Hydroxyvitamin D Concentration
Is Vitamin D2 Treatment-associated Decrease in 25(OH)D3 Level a Reciprocal Phenomena?
Several studies have demonstrated that D2 treatment is associated with a decrease in 25(OH)D3 level and therefore have proposed that D3 would be preferable in term of raising total 25(OH)D level.
- Trial name
- NCT03035084
- Testing
- Vitamin D3, Vitamin D2
- Where
- Saudi Arabia
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- King Faisal Specialist Hospital & Research Center
Postoperative Pain
Does Ultrasound Improve Procedural Time in the Lateral Popliteal Approach to the Sciatic Nerve in Obese Patients
Ultrasound have been shown to improve the time needed to locate and block nerves in the non obese population. However, its utility is still unknown in the obese population.
- Trial name
- NCT01579747
- Testing
- Ultrasound, Nerve stimulation
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- University of New Mexico
Obesity, Lumbar Spine Surgery
WoundVac in Obese Patients Undergoing Lumbar Surgery
This is an open label, randomized clinical trial of Closed-Incision Negative-Pressure Therapy to decrease post-operative wound complications in patients with BMI ≥35kg/m2 after posterior lumbar spine surgery.
- Trial name
- NCT03688438
- Testing
- Closed-Incision Negative-Pressure Therapy
- Where
- United States
- Volunteers
- 124 people
- Sponsor
- Norton Leatherman Spine Center
Type 2 Diabetes Mellitus (T2DM), Overweight , Obesity
A Study to Evaluate Different Administration Conditions and the Food Effect of MWN109 Tablets in Chinese Participants
This is a randomized, open-label, multiple-dose study to evaluate the effects of different volumes of administration water, post-dose fasting duration, and high-fat diet on the pharmacokinetics of the 15 mg dose of MWN109 tablets…
- Trial name
- NCT07801326
- Testing
- MWN109 Tablets
- Where
- China
- Volunteers
- 162 people, healthy volunteers welcome
- Sponsor
- Shanghai Minwei Biotechnology Co., Ltd
Diabetes Mellitus Type 2, Non-alcoholic Fatty Liver Disease
Efficacy of Amlexanox vs. Placebo in Type 2 Diabetic Patients
This study involves research about an investigational medicine called Amlexanox. The reason for this study is to find out how Amlexanox can improve type 2 diabetes, insulin resistance, obesity and non-alcoholic fatty liver…
- Conditions
- Diabetes Mellitus Type 2, Non-alcoholic Fatty Liver Disease, Obesity
- Trial name
- NCT01975935
- Testing
- Amlexanox
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- University of Michigan
Food, Eating
The Effect of Dairy and Non-Dairy Snacks on Food Intake, Subjective Appetite in Children
Dairy products have the potential to be healthy snack foods for children and are provided in a variety of food matrices. For instance, milk represents a fluid product, yogurt can be classified as a semi-solid food, and finally…
- Conditions
- Food, Eating, Appetite
- Trial name
- NCT02484625
- Testing
- Potato chips, Greek yogurt, Cookies
- Where
- Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Mount Saint Vincent University
Healthy, Overweight and/or Obese Subjects
Clinical Trial to Study the Safety Tolerability, Pharmacokinetics, Food Effect & Pharmacodynamics of a New Compound P7435 in Healthy, Overweight and/or Obese Subjects
Clinical trial to study the safety tolerability, pharmacokinetics, food effect and pharmacodynamics of a new compound P7435 in in healthy, overweight and/or obese subjects
- Trial name
- NCT01764425
- Testing
- P7435
- Where
- 2 sites in India
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Piramal Enterprises Limited
Overweight, Glucose Metabolism Disorders
The Physical Activity and Nutrition in Children (PANIC) Study
The Physical Activity and Nutrition in Children (PANIC) Study is a single-centre controlled trial on the effects of a combined physical activity and dietary intervention on cardiometabolic risk factors and other health outcomes…
- Conditions
- Overweight, Glucose Metabolism Disorders, Lipid Metabolism Disorders, Blood Pressure
- Trial name
- PANIC (NCT01803776)
- Testing
- lifestyle counseling
- Where
- Finland
- Volunteers
- 504 people, healthy volunteers welcome
- Sponsor
- University of Eastern Finland
Obesity
A Research Study Looking at How 50 mg Semaglutide Daily Affects Food Intake and Emptying of the Stomach in People With Obesity
This study tests if semaglutide tablets of 50 mg can help people with obesity to lower their food intake compared to placebo. This study also tests how semaglutide 50 mg works on appetite, control of eating (such as cravings and…
- Trial name
- NCT05236517
- Testing
- Semaglutide D Dose 1, Semaglutide D Dose 2, Semaglutide D Dose 3
- Where
- Germany
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Novo Nordisk A/S
Polycystic Ovary Syndrome, Metabolic Syndrome
Metabolic Syndrome in PCOS: Precursors and Interventions
The purpose of this study is to investigate the metabolic effects of anti-androgens and oral contraceptive pills (OCPs), compared with placebo, in the treatment of women with PCOS.
- Trial name
- NCT00442689
- Testing
- flutamide, ethinyl estradiol 35 mcg and drospirenone 3 mg
- Where
- United States
- Volunteers
- 97 people
- Sponsor
- Northwestern University
Overweight, Hypercholesterolemia
Supplementation of Alpha-linolenic Acid (ALA)-Rich Oil in Humans
The objective of this study is to investigate the accumulation of n-3 LC-PUFA (EPA, DPA and DHA) in human lipids by oral supplementation of ALA-rich linseed oil.
- Trial name
- ALA_KK (NCT01317290)
- Testing
- n-3 PUFA free olive oil, linseed oil
- Where
- Germany
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- University of Jena
Metabolically Healthy Obesity, Intermittent Fasting
Healthy vs Unhealthy Obesity: Mehanistic Insights and Effects of Time-Restricted Eating
Obesity-related cardiometabolic diseases are now a leading cause of death worldwide. These diseases result from a dysfunctional adipose tissue (AT) that induces inflammation, insulin resistance and altered endocrine function.
- Trial name
- NCT05136313
- Testing
- Time-restricted eating
- Where
- Chile
- Volunteers
- 53 people
- Sponsor
- Instituto de Nutrición y Tecnología de los Alimentos
Obesity Prevention
A Randomized Clinical Trial of Home-based Exercise Combined With a Slight Caloric Restriction on Obesity Prevention Among Women
The study investigated the effectiveness of home-based exercise combined with a slight caloric restriction on weight change during 12 months in non-obese women.
- Trial name
- NCT01206413
- Testing
- Low glycemic index diet, High glycemic index diet, Home-based exercise intervention
- Volunteers
- 203 people, healthy volunteers welcome
- Sponsor
- Rio de Janeiro State University
Obesity
A Pilot Study of the Efficacy and Program Cost-effectiveness of Prevention Plus for Childhood Obesity
In 2007 the Expert Committee published recommendations on the prevention and treatment of childhood obesity. These recommendations outlined four interventions intended for advancement based on the child's age, body mass index…
- Trial name
- NCT01358448
- Testing
- growth monitoring, Growth Monitoring plus Family-based Behavioral Counseling
- Where
- 2 sites in United States
- Volunteers
- 22 people
- Sponsor
- The University of Tennessee, Knoxville
Inflammation, Malnutrition
Effects of Camelina Sativa Oil in Free-living Older Adults
The present study aims at evaluating the anti-inflammatory effects of a novel food in older adult volunteers. Briefly, this randomized, double-blind and placebo-controlled study is performed on 91 apparently healthy older adults…
- Conditions
- Inflammation, Malnutrition, Hyperglycemia, Dyslipidemias
- Trial name
- NCT04965948
- Testing
- Novel food snack
- Where
- Italy
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- University of Pavia
Obesity
Noom Coach for Bariatric Health
Mobile technologies/smartphone applications offer a means to effect behavior change without significant obstacles that typically limit implementation of empirically supported therapies (e.g., in-person sessions); however…
- Trial name
- NCT03887078
- Testing
- Noom Coach for Bariatric Health
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Noom Inc.
Diabetes, Obesity
Prospective Metabolic Surgery in T2DM Chinese Subjects
The primary goal of this study is to assess impact of metabolic surgery on glycemic control in diabetic patients.
- Trial name
- NCT02217943
- Testing
- Roux-en-Y gastric bypass, Sleeve gastrectomy
- Where
- 6 sites in China
- Volunteers
- 101 people
- Sponsor
- Ethicon Endo-Surgery
Obesity
Exercise Dose Response for Improving Insulin Sensitivity
Many of the beneficial metabolic effects of endurance exercise training are not due to adaptations to weeks, months, or even years of training, but rather much is due to the response to the most recent exercise session(s).
- Trial name
- NCT01452035
- Testing
- Exercise
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Overweight, Obesity
Effect of Intake of Dehydrated Nopal Powder From Highly Mature Cladodes on the Lipid Profile
Background: Opuntia ficus-indica is a plant from the cactus family (Cactaceae) that is widespread and of great economic importance in Mexico.
- Conditions
- Overweight, Obesity, Dyslipidemia
- Trial name
- NCT07018908
- Testing
- supplementation with 5 g dehydrated nopal powder from highly mature cladodes, supplementation with 15 g dehydrated nopal powder from highly mature cladodes, Control Group (only diet)
- Where
- Mexico
- Volunteers
- 35 people
- Sponsor
- Universidad Autónoma de Querétaro
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