Clinical trials: Nutraceutical
Non-alcoholic Fatty Liver Disease
Efficacy of a Natural Components Mixture in the Treatment of Non Alcoholic Fatty Liver Disease (NAFLD)
The objective of this study is to provide clinical data to support the effectiveness of a mixture of ingredients of natural origin, suitably selected and packaged, in the protection from liver damage, in subjects with NAFLD.
- Trial name
- NUTRAFAST (NCT02369536)
- Testing
- nutraceutical mixture
- Where
- Italy
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Neuromed IRCCS
Chronic Fatigue Syndrome
Therapy for Chronic Fatigue Syndrome: A Presumptive Mitochondrial Disorder
The purpose of this study is to determine whether therapy that has been shown to be beneficial for mitochondrial diseases is also beneficial for Chronic Fatigue Syndrome (CFS) patients.
- Trial name
- NCT01872351
- Testing
- Nutraceuticals
- Where
- United States
- Sponsor
- Columbia University
Type 2 Diabetes
Nutraceutical Citrulline in Pregnancy
The purpose of this study is to determine if oral of L-citrulline (3 grams/day) for 3 weeks provided in mid-pregnancy to pregnant women with type 2 diabetes will increase the plasma L-arginine/ADMA ratio, lower maternal blood…
- Trial name
- NCT02772887
- Testing
- L-Citrulline
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- University of Pittsburgh
Cognitive Impairment, Old Age; Debility
Dietary Supplementation and Cognitive Functions in the Elderly
In recent years, globally, there has been a growth in both the size and the proportion of older adults in the world population. The World Health Organization (WHO) has estimated that by 2030, 1 in 6 people will be 60 years of age…
- Trial name
- ESPINS (NCT06352099)
- Testing
- Dietary supplement with micronised diosmin, hesperidin and herbal extracts
- Where
- Italy
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Dyslipidemias, Diabetes Mellitus, Type 2
Use of Nutraceuticals in Clinical Practice
The aim of this study will be to evaluate the use of the nutraceutical with cardio-metabolic actions in clinical practice in addition to a Mediterranean diet scheme, normally recommended in the clinic.
- Conditions
- Dyslipidemias, Diabetes Mellitus, Type 2, Hypertension
- Trial name
- NCT04161859
- Testing
- Nutraceutical
- Where
- Italy
- Volunteers
- 387 people
- Sponsor
- University of Pavia
Obesity
Anti-psychotic Medication (New Use) Weight Loss Study
This is a pilot study to determine the safety and efficacy of an investigational product (IHBG-10) on weight change and changes in body composition in subjects who have just started taking (for less than three months) certain…
- Trial name
- NCT01272752
- Testing
- IHBG-10
- Where
- United States
- Sponsor
- Avera McKennan Hospital & University Health Center
Overweight/Obesity, Insulin Resistance
Efficacy of Hydroxycinnamates and Beta-glucans as a Dietary Tool Against Obesity (OBHEALTH)
The study aimed at assessing the effect of a decaffeinated green coffee extract, rich in hydroxycinnamates, oat beta-glucans or the combination of both bioactive compounds on overweight/obese subjects with hyperglycemia.
- Trial name
- OBHEALTH (NCT05009615)
- Testing
- Green coffee extract, Beta glucan, Green coffee + beta-glucan
- Where
- Spain
- Volunteers
- 30 people
- Sponsor
- Instituto de Ciencia y Tecnología de Alimentos y Nutrición
Irritable Bowel Syndrome, Irritable Bowel Syndrome With Diarrhea
Effect of Consuming a Nutraceutical Composition on Signs and Symptoms in Adult Patients With Irritable Bowel Syndrome
Irritable bowel syndrome is characterized by the presence of chronic, recurrent abdominal pain, alterations in bowel habits, and abdominal distension. The medical diagnosis is made using the Rome IV criteria.
- Conditions
- Irritable Bowel Syndrome, Irritable Bowel Syndrome With Diarrhea, Irritable Bowel Syndrome With Constipation, Irritable Bowel Syndrome Mixed
- Trial name
- NCT07103772
- Testing
- Ananá
- Where
- Mexico
- Volunteers
- 94 people
- Sponsor
- Universidad Autonoma de Nuevo Leon
Alzheimer's Disease
Phase 2 Study to Examine Grape Seed Extract as an Anti-Oligomerization Agent in Alzheimer's Disease (AD)
Alzheimer Disease (AD) is a progressive brain disease generally known as senile dementia. Our proposed study will establish safety and pharmacokinetics of Meganatural-AZ GSPE in AD subjects.
- Trial name
- NCT02033941
- Testing
- Meganatural-Az Grapeseed Extract
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Hillel Grossman
Iron Deficiency (Without Anemia)
Effect of Ferrous iROn and cUrcumin sTatus on Inflammatory and Neurotrophic markErs
INTRODUCTION: Iron is a vital nutrient for many physiological processes including DNA production, oxygen transport and neuronal processes.
- Trial name
- Fe-ROUTINE (NCT04465851)
- Testing
- Ferrous Sulphate 65 mg, Curcumin, Ferrous Sulphate 18mg
- Where
- United Kingdom
- Volunteers
- 155 people, healthy volunteers welcome
- Sponsor
- University of Westminster
Obesity
Study of the Nutraceutical Properties and Health Benefits of Traditional Components of the Mediterranean Diet
The present protocol is designed to conduct nutrigenomic and nutrigenetic studies on foods conforming to the Mediterranean diet, in order to determine the effect functional foods have on blood parameters (cholesterol metabolism…
- Trial name
- NCT01890070
- Testing
- Hazelnuts, Chocolate, Red wine
- Where
- Italy
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Rome Tor Vergata
Coronary Artery Disease
Cholesterol-lowering Effects of nutraceuticaLs Versus Ezetimibe in Statin-intolerant Patients
Treatment with statins has a class I indication after percutaneous coronary intervention (PCI), but is often discontinued by patients due to side effects.
- Trial name
- CHOLESS (NCT01807078)
- Testing
- Ezetimibe, Nutraceuticals
- Where
- Italy
- Volunteers
- 200 people
- Sponsor
- University of Roma La Sapienza
Sensorineural Hearing Loss, Tinnitus
ACEMg Hearing Preservation, Tinnitus and Hyperacusis Relief
ACEMg (Soundbites) is a neuroprotectant supplement designed to block the initiating biological events in the inner ear leading to inner ear hearing loss, sensorineural hearing loss, SNHL, which accounts for more than 90% of all…
- Conditions
- Sensorineural Hearing Loss, Tinnitus, SNHL, Inner Ear Hearing Loss
- Trial name
- OTISRWD (NCT06477354)
- Testing
- ACEMg
- Where
- United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Keep Hearing, Inc.
Colorectal Cancer, Surgery--Complications
Effect of the Nutraceutical "MICODIGEST 2.0" on the Complications After Surgery for Colorectal Cancer
Most of Colorectal cancer (CRC) diagnosed are candidates for surgical resection with curative intent, although colorectal surgery is associated with some complications that could be life-threatening.
- Trial name
- NCT04821258
- Testing
- MICODIGEST 2.0 supplement
- Where
- Spain
- Volunteers
- 48 people
- Sponsor
- Fundacin Biomedica Galicia Sur
Hypercholesterolemia
Long Term Efficacy and Tolerability of a Nutraceutical Combination (Red Yeast Rice, Policosanols and Berberine) in Low-moderate Risk Hypercholesterolemic Patients: a Double-blind, Placebo Controlled Study
Background: Statins are at the forefront of strategies to manage hypercholesterolemia. However, 10-15% of patients result to be intolerant to any statins, even at low daily doses and almost one- third of statin users discontinue…
- Trial name
- NCT02078167
- Testing
- nutraceutical combination (red yeast rice, policosanols and berberine)
- Volunteers
- 60 people
- Sponsor
- Comitato Etico di Area Vasta Sud Est
Muscle Loss
Leucine-enriched Nutraceutical and Attenuating Muscle Loss
This leucine-enriched protein gummy (as a gummy bar/slab) will be studied to address age-related loss of muscle mass and strength/function in older persons.
- Trial name
- NCT03197402
- Testing
- Leucine-enriched protein gel delivery system, Milk protein gel delivery system
- Where
- 4 sites in Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- McMaster University
Androgenic Alopecia, Hair Loss/Baldness
Study to Evaluate Xtressé Gummy Supplement in Men With Androgenic Alopecia
The goal of this study is to determine if Xtresse' gummy is safe and may help regrow hair in men with androgenic alopecia (common pattern hair loss).
- Conditions
- Androgenic Alopecia, Hair Loss/Baldness, Hair Thinning
- Trial name
- NCT07637071
- Testing
- Xtressé Hair Growth Gummies
- Where
- 2 sites in United States
- Volunteers
- 48 people
- Sponsor
- Restore Biologics Holdings, Inc. dba Xtressé
Hypercholesterolemia
Nutraceutical in Cardiovascular Primary Prevention
Nutraceuticals have attracted interest as possible approach to be associated with lifestyle changes for lowering plasma cholesterol levels in patients with moderate hypercholesterolemia.
- Trial name
- NIRVANA (NCT03216811)
- Testing
- nutraceutical
- Where
- Italy
- Volunteers
- 52 people
- Sponsor
- University Hospital of Ferrara
Joint Discomfort, Musculoskeletal Pain
A Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Effects of resO™ Bone and Joint Support Postbiotic on Physical Function, Pain Interference, and Mobility in Adults With Joint Discomfort
This randomized, double-blind, placebo-controlled study evaluates the effects of resO™ Bone and Joint Support Postbiotic on physical function, pain interference, mobility, and recovery in adults aged 18-75 years experiencing…
- Conditions
- Joint Discomfort, Musculoskeletal Pain, Mobility Limitation
- Trial name
- RESO101 (NCT07602426)
- Testing
- Supplement
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Able Biolabs, LLC
Close Contacts of Active Tuberculosis
Efficacy of Nyaditum Resae(R) Against Active TB in Georgia
The use of a supplement food like "Nyaditum resae" is a reliable opportunity to stop the progression towards active TB through the most updated knowledge of this disease:the induction of tolerance.
- Trial name
- NCT02897180
- Testing
- Nyaditum resae(R)
- Where
- Georgia
- Volunteers
- 3,300 people, healthy volunteers welcome
- Sponsor
- Fundació Institut Germans Trias i Pujol