Clinical trials: Numbness
Teeth Staining, Numbness of the Tongue and Soft Tissue
Children Acceptance of AgNP Mouthwash Against Chlorhexidine 0.12% and Chlorhexidine .2% Mouthwashs
This study aims to evaluate and compare the children's acceptance of mouthwash containing silver nanoparticles versus Chlorhexidine 0.12% \& Chlorhexidine 0.2%
- Conditions
- Teeth Staining, Numbness of the Tongue and Soft Tissue, Bitter Taste
- Trial name
- NCT07200063
- Testing
- nano silver mouthwash, Chlorhexidine mouthwash (0.12%), Chlorhexidine mouthwash (0.2%)
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- Cairo University
Palmar and Plantar Erythema, Numbness of the Four Limbs
Traditional Chinese Medicine Treatment for Capecitabine-Related Hand-Foot Syndrome
This study is a prospective, single-center, randomized, parallel-group, open-label clinical trial titled "Intervention with the 'Xu Xue Tong Luo Traditional Chinese Medicine Compound for Capecitabine-Related Hand-Foot Syndrome."…
- Conditions
- Palmar and Plantar Erythema, Numbness of the Four Limbs, Pain in the Distal Extremities, Peeling of the Soles and Palms
- Trial name
- NCT07883642
- Testing
- Twelve-Ingredient Prepared Sichuan Aconite Hand and Foot Bath, Standard Basic Nursing Interventions
- Volunteers
- 7 people
- Sponsor
- Emeishan Hospital of Traditional Chinese Medicine
Chemotherapy Induced Peripheral Neuropathy (CIPN), Paresthesia
Gut Microbiome Profiles in Patients With Chemotherapy-induced Neuropathy in the RCT OzoParQT (NCT06706544).
Chemotherapy-induced peripheral neuropathy (CIPN) is a common and debilitating side effect of chemotherapy (CT), often requiring dose reductions or treatment interruptions, which can compromise efficacy of the planned CT…
- Conditions
- Chemotherapy Induced Peripheral Neuropathy (CIPN), Paresthesia, Numbness, Tingling
- Trial name
- OzoParQTmicrob (NCT06799351)
- Testing
- Ozone therapy
- Where
- Spain
- Volunteers
- 42 people
- Sponsor
- Bernardino Clavo, MD, PhD
Sensation Disorders, Sensation, Phantom
Prospective Study of Sensation and Satisfaction in Cancer and Transgender Mastectomy Patients
During breast surgery, sensory nerves are cut which may lead to reduced sensation and pain. Surgical reinnervation techniques have been developed with the aim of improving postoperative sensation by preserving the nerves and…
- Conditions
- Sensation Disorders, Sensation, Phantom, Pain, Postoperative, Pain, Chronic
- Trial name
- NCT06094257
- Testing
- Sensory testing
- Where
- 2 sites in United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
Chemotherapy Induced Peripheral Neuropathy (CIPN), Paresthesia
Ozone Treatment in Paresthesia (Numbness, Tingling) Secondary to Chemotherapy-induced Peripheral Neuropathy
The goal of this phase II/III randomized clinical trial is to evaluate the effect of adding rectal ozone therapy to the usual management of patients with paresthesia (numbness and/or tingling) due to chemotherapy-induced…
- Conditions
- Chemotherapy Induced Peripheral Neuropathy (CIPN), Paresthesia, Numbness, Tingling
- Trial name
- OzoParQT (NCT06706544)
- Testing
- Ozone therapy
- Where
- Spain
- Volunteers
- 42 people
- Sponsor
- Bernardino Clavo, MD, PhD
Pain, Postoperative, Numbness
Lidocaine Versus Bupivacaine in Orthognathic Surgery
In this research study, we want to learn more about the impact of two different local anesthetics (bupivacaine and lidocaine) on patient experience following orthognathic (jaw) surgery.
- Conditions
- Pain, Postoperative, Numbness, Temperature Sensation, Perception of Touch
- Trial name
- NCT06450028
- Testing
- 10 cc of 0.25% bupivacaine hydrochloride with 1:200,000 epinephrine, 6.8 cc of 2% lidocaine hydrochloride with 1:100,000 epinephrine
- Where
- United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Boston Children's Hospital
Cervical Radiculopathy, Cervical Radicular Pain
Effects of Exercises and Electrical Current Application Aiming to Strengthen Neck and Shoulder Blades Muscles on Symptoms of a Pinched Nerve in the Neck
Cervical Radiculopathy (CR) is an objective loss of sensory and/or motor function as a result of compression or irritation of the cervical spinal nerve root.
- Conditions
- Cervical Radiculopathy, Cervical Radicular Pain, Neck Pain, Numbness
- Trial name
- NCT07375823
- Testing
- Exercise Therapy, Superimposition of electrical muscle stimulation on active movement
- Where
- Cyprus
- Volunteers
- 50 people
- Sponsor
- European University of Lefke
Healthy, Cyclists
Effects of Contemporary Cycling Saddle Designs on Penile Transcutaneus Oxygen and Carbon Dioxide Levels in Elite Road Cyclists Riding on a Stationary Trainer
Aim of this research is to compare novel 3D printed cycling saddle with the bestselling saddles from two major cycling manufacturers in terms of effects on penile blood gasses and update these findings on current style of racing…
- Conditions
- Healthy, Cyclists, Blood Gas Monitoring, Transcutaneous, Penile Numbness
- Trial name
- EC-SADDLE (NCT05887193)
- Testing
- Biothesiometry, Transcutaneous blood gas monitoring, Cycling on a home trainer
- Where
- Czechia
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Milan Martínek
Penile Numbness
Vacuum Therapy for the Treatment of Penile Numbness/Sensory Changes
This is a prospective, uncontrolled, Hypothesis generating study. A total of eight adult male participants experiencing penile insensitivity will be recruited through the Ottawa Hospital's Men's Health Clinic.
- Trial name
- NCT07171567
- Testing
- Vacuum erection device
- Where
- Canada
- Volunteers
- 8 people
- Sponsor
- Ottawa Hospital Research Institute
Pain, Fear of Pain
Effectiveness of TKTX Cream on Pain and Fear in Children During Venipuncture: A Randomized Controlled Trial
Venipuncture, the process of obtaining blood samples for diagnostic purposes, is a common medical procedure performed worldwide. However, it can be associated with varying levels of pain and discomfort for patients.
- Conditions
- Pain, Fear of Pain, Venipuncture Site Numbness
- Trial name
- NCT05957718
- Testing
- TKTX cream
- Where
- Iraq
- Volunteers
- 88 people
- Sponsor
- Uppsala University
Chemotherapy-Induced Peripheral Neuropathy, Numbness
Fingolimod in Treating Patients With Chemotherapy-Induced Neuropathy
This early phase I trial studies how well fingolimod works in treating patients with chemotherapy-induced nerve pain (neuropathy). Fingolimod acts by suppressing immune reactions in the brain.
- Conditions
- Chemotherapy-Induced Peripheral Neuropathy, Numbness, Pain, Tingling
- Trial name
- NCT03943498
- Testing
- Fingolimod, Fingolimod Hydrochloride, Questionnaire Administration
- Where
- 2 sites in United States
- Volunteers
- 2 people
- Sponsor
- Mayo Clinic
Skin Numbness and Kneeling Ability
Comparison of Midline With Lateral Skin Incision in Simultaneous Bilateral TKA
This is a RCT which compare skin numbness, kneeling ability and functional outcome between midline incision and lateral incision in patients undergoing simultaneous bilateral TKA
- Trial name
- NCT04240847
- Testing
- Skin incision
- Where
- Thailand
- Volunteers
- 30 people
- Sponsor
- Thammasat University
Burning Pain, Impaired Balance
Feasibility Study of New Method of Diagnostic and Prediction of Painful CIPN
This clinical trial studies how well Diode laser fiber type Selective Stimulator (DLss) works in predicting pain development in patients with ovarian cancer who are receiving chemotherapy.
- Conditions
- Burning Pain, Impaired Balance, Malignant Ovarian Neoplasm, Numbness
- Trial name
- NCT03206216
- Testing
- Diode Laser fiber type Selective Stimulator (DLss)
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Stanford University
Agitation, Anxiety
Learning Oriented Physiotherapy - a New Approach
Outpatients that suffer from different anxiety disorders may have physical ailments that negatively affect daily life functioning and quality of life.
- Conditions
- Agitation, Anxiety, Dizziness, Pain
- Trial name
- LOF (NCT02194036)
- Testing
- Learning Oriented Physiotherapy, Widely Recognized Psychiatric Treatment
- Where
- 3 sites in Norway
- Volunteers
- 81 people
- Sponsor
- Helse Nord-Trøndelag HF
Phythoterapy, Venipuncture Site Numbness
Antiseptic and Analgesic Action Acmella Oleracea Skin: Randomized Clinical Trial
Context: Research on natural products with therapeutic, analgesic or antimicrobial purpose should be encouraged to create new drugs.
- Conditions
- Phythoterapy, Venipuncture Site Numbness, Antimicrobial, Analgesic
- Trial name
- NCT02792972
- Testing
- A. oleracea, 70% alcohol
- Volunteers
- 60 people
- Sponsor
- Ana Beatriz Alkimim Teixeira Loyola
Nerve Conduction, Numbness
Geranium Oil and Its Components for the Relief of Numbness-OB 100
This study is designed to evaluate the effectiveness of geranium oil and its components in the relief of numbness and the restoration of sensations.
- Trial name
- NCT01022437
- Testing
- Geranium Oil with component PN-34
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Pennington Biomedical Research Center
Postoperative Pain, Foot Numbness
Ultrasound Guidance Versus Electrical Stimulation for Continuous Popliteal-Sciatic Nerve Blocks
Research study to determine if pain relief following foot and/or ankle surgery is influenced by the technique used to place perineural catheter.
- Trial name
- NCT00876681
- Testing
- Popliteal catheter placed via ultrasound or electrical stimulation
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- University of California, San Diego
Soft Tissue Anesthesia (Numbness)
Safety and Efficacy Study of NV-101 in Dental Patients
The purpose of this study was: to determine if NV-101 accelerates recovery from numbness compared to placebo to evaluate safety of NV-101
- Trial name
- NCT00154167
- Testing
- NV-101 (phentolamine mesylate solution)
- Where
- United States
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- Novalar Pharmaceuticals, Inc.