Clinical trials: Noncommunicable Diseases
Arterial Hypertension
"Community-based, eHealth Supported Management of Cardiovascular Risk Factors by Lay Village Health Workers (ComBaCaL aHT TwiC 1 & ComBaCaL aHT TwiC 2)
ComBaCaL aHT TwiC 1 and aHT TwiC 2 are two cluster-randomized controlled trials that are identical in intervention, design and endpoints.
- Trial name
- NCT05684055
- Testing
- First-line antihypertensive single-pill combination (SPC), Standardized counselling and referral to the closest health facility
- Where
- 2 sites in Lesotho, Switzerland
- Volunteers
- 1,354 people
- Sponsor
- University Hospital, Basel, Switzerland
Atopic Dermatitis, Food Allergy in Children
Preventing Atopic Dermatitis and ALLergies in Children
The primary objective is of the PreventADALL study is to test if primary prevention of allergic diseases is possible by simple and low cost strategies, and secondary to asses the impact of xenobiotic exposure and microbiota in…
- Conditions
- Atopic Dermatitis, Food Allergy in Children, Asthma, Rhinitis, Allergic
- Trial name
- PreventADALL (NCT02449850)
- Testing
- Food intervention, Skin care
- Where
- Norway
- Volunteers
- 2,701 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
Surveys and Questionnaires, Noncommunicable Diseases
Use of Airtime Incentives to Improve Short Message Service Surveys in Colombia and Tanzania
This study evaluates the effect of four different airtime incentive amounts on short message service (SMS) survey cooperation, response, refusal and contact rates, as compared to control group, in Colombia and Tanzania.
- Trial name
- NCT03768934
- Testing
- 1X airtime incentive, 2X airtime Incentive, Lottery airtime incentive
- Where
- 2 sites in Colombia, Tanzania
- Volunteers
- 2,151 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Surveys and Questionnaires, Noncommunicable Diseases
Use of Airtime Structure to Improve Interactive Voice Response Surveys in Bangladesh and Uganda
This study evaluates the effect of three different airtime incentive structures on interactive voice response (IVR) survey cooperation, response, refusal and contact rates, as compared to a control group, in Bangladesh and Uganda.
- Trial name
- NCT03773146
- Testing
- 1X Airtime Incentive, Lottery Airtime Incentive
- Where
- 2 sites in Bangladesh, Uganda
- Volunteers
- 4,550 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Cardiovascular Risk Factor
Surveillance of Cardiovascular Risk Factors in Cameroonian Garrison
Purpose: The objective of our study was to assess the cardiovascular risk of a Cameroonian military population and compare it to the cardiovascular risk of the neighboring civilian population.
- Trial name
- NCT04315441
- Testing
- STEPS and AUDIT questionnaires
- Volunteers
- 566 people, healthy volunteers welcome
- Sponsor
- Support and Education Technic Centre
Anemia and Pregnancy, Metabolism and Foetal Growth
Foetal Exposure and Epidemiological Transition: Role of Anaemia in Early Life for Non-communicable Diseases Later
Study Hypotheses: 1. Anaemia, which is frequent before conception as well as during early pregnancy, affects metabolism and foetal growth trajectories, influencing the risk of NCDs in the offspring. 2.
- Conditions
- Anemia and Pregnancy, Metabolism and Foetal Growth, Epigenetics
- Trial name
- FOETALforNCD (NCT02191683)
- Where
- Tanzania
- Volunteers
- 1,748 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Diabetes Mellitus, Diabetic Neuropathies
Integrated Oral Care Intervention for Xerostomia in Diabetes Patients
Diabetes patients commonly experience dry mouth also known as xerostomia which can affect eating speaking oral health and overall quality of life.
- Trial name
- IOCID (NCT07425275)
- Testing
- Integrated Oral Care Intervention
- Where
- Pakistan
- Volunteers
- 80 people
- Sponsor
- Khyber Medical University Peshawar
Non-communicable Diseases (NCDs)
Community-Based Chronic Disease Care in Rural Lesotho
This ComBaCaL cohort study is to assess the impact of community-based, lay-led chronic disease screening and care interventions in rural Lesotho.
- Trial name
- ComBaCaL (NCT05596773)
- Where
- 2 sites in Lesotho, Switzerland
- Volunteers
- 17,500 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Academic Performance; Primary Prevention; Physical Activity
Active Smarter Kids: A Cluster-randomized Controlled Trial
The relationship between physical activity and academic performance has received widespread attention owing to the pressure on schools to graduate pupils who meet accepted academic standards.
- Trial name
- ASK (NCT02132494)
- Testing
- Physical activity
- Where
- Norway
- Volunteers
- 1,202 people
- Sponsor
- Western Norway University of Applied Sciences
Chronic Obstructive Pulmonary Disease (COPD), Acute Coronary Syndrome
Feasibility Study of a Digital Interactive Life-style Platform for Individuals After Rehabilitation
The goal of this clinical trial is to evaluate the feasibility and usability of a digital lifestyle platform designed to support patients after discharge from inpatient rehabilitation.
- Conditions
- Chronic Obstructive Pulmonary Disease (COPD), Acute Coronary Syndrome, Fragility Fracture, Minor Stroke
- Trial name
- Feas Platf (NCT07597031)
- Testing
- Digital Lifestyle Platform, Usual Care (Standard Post-Rehabilitation Care)
- Where
- 2 sites in Switzerland
- Volunteers
- 240 people
- Sponsor
- Matthias Wilhelm, MD
Non-communicable Diseases (NCD), Addiction to Opioids
Systematic Examination of Health Inequalities: Documentation, Patterns, and Determinants
The existence of social inequalities is a major global issue and a salient challenge for the European Union. During COVID-19 pandemic, health disparities became more evident.
- Conditions
- Non-communicable Diseases (NCD), Addiction to Opioids, Incarceration, Opioid-use Disorders
- Trial name
- CHANCE (NCT07558187)
- Where
- 5 sites in Greece
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- University of Thessaly
Metabolic Associated-dysfunction Steatotic Liver Disease (MASLD), Metabolic Associated-dysfunction Steatohepatitis (MASH)
Behavioral Lifestyle Intervention for Metabolic Dysfunction-associated Steatotic Liver Disease (MASLD) in Adults
The goal of this randomized control trial study is to compare an acceptance-based weight loss program with an occupational therapy behavioral lifestyle modification intervention in adults with metabolic associated-dysfunction…
- Trial name
- NCT06121999
- Testing
- Standard of care acceptance-based behavioral weight loss program, Occupational therapy dietary and lifestyle modifications
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Grand Valley State University
Diabete Mellitus, Cardiovascular Disease Risk Factor
The Mauritius and Rodrigues Non-Communicable Disease (NCD) Study
Mauritius is located in the southern Indian Ocean with a population of 1.3 million in 2023. Mauritius is a multiethnic nation with 68% South Asian, 27% African (Creole), 3% Chinese and 2% Franco Mauritians.
- Conditions
- Diabete Mellitus, Cardiovascular Disease Risk Factor, Ischemic Cardiovascular Disease, Hypertension
- Trial name
- NCT07048717
- Where
- Mauritius
- Volunteers
- 39,082 people, healthy volunteers welcome
- Sponsor
- Umeå University
Gestational Diabetes Mellitus (GDM)
Implementation and Evaluation of Bump2Baby and Me+ Programme for Gestational Diabetes Mellitus in Routine Maternity Care Setting.
Gestational diabetes mellitus (GDM) affects approximately 1 in 7 pregnancies globally and is associated with significant short and long-term health consequences for both mothers and infants.
- Trial name
- B2B&ME+ (NCT07189221)
- Testing
- Life Style Intervention
- Volunteers
- 3,600 people
- Sponsor
- University College Dublin
HIV Infections, Non Communicable Diseases
Geriatric HIV Cohort in Sub Sahara Africa
The overall goal of the proposal is to improve capacity for detection and management of non-communicable diseases and geriatric syndromes in the aging HIV population in sub-Saharan Africa
- Conditions
- HIV Infections, Non Communicable Diseases, Aging
- Trial name
- HASA (NCT04313699)
- Testing
- Antiretroviral treatment
- Volunteers
- 500 people
- Sponsor
- Makerere University
Package of Essential Non-Communicable Diseases (PEN), Peer Coaching
PEN Implementation Study
There is a gap in the implementation of PEN services as well as in the monitoring and evaluation of the WHO PEN in Nepal. One reason for such gaps is due to a lack of team-based care in low-resource settings like Nepal.
- Conditions
- Package of Essential Non-Communicable Diseases (PEN), Peer Coaching, Clinical Audit, Mixed Method Implementation Study
- Trial name
- NCT05880784
- Testing
- Reinforcement of Peer coaching and clinical audit, Continuation of usual practice without intervention
- Where
- Nepal
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Shahid Gangalal National Heart Centre
Body Weight Maintenance, Nutritional and Metabolic Diseases
Effects of Daily Eating Duration on Health
This study would recruit about 50 healthy adult women and randomly divide the participants into two groups for a ten-week crossover intervention study.
- Trial name
- NCT05964179
- Testing
- time extended feeding, time restricted feeding
- Where
- South Korea
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Chung-Ang University
Pregnant Women
Impact of UFPs and MNPs on Fetal Health
This project aims at unravelling mechanisms by which exposure to air pollution (in particular Ultrafine Particulate (UFP, PM0.1), and micro nano plastic's) interferes with the normal foetus development, with a short-term causal…
- Trial name
- UPRISE (NCT07238608)
- Where
- Spain
- Volunteers
- 1,600 people
- Sponsor
- Instituto de Investigacion Sanitaria La Fe
Health Risk Behaviors, Non Communicable Diseases
Compare Smokers' Appraisal of Proposed Plain Packs and Existing Cigarette Packs
2 Objectives 1. To explore the noticeability of pictorial health warnings and perceptions of attractiveness and harmfulness towards plain cigarette packets and existing cigarette packets with 85% pictorial warnings in current…
- Trial name
- NCT05907226
- Where
- Hong Kong
- Volunteers
- 1,283 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Surveys and Questionnaires, Non Communicable Diseases
Comparison of IVR and CATI Surveys in Bangladesh
This study focuses on mechanisms to adapt the performance of interactive voice response (IVR) and computer assisted telephone interviews (CATI) surveys conducted in low-and middle-income (LMIC) setting (Bangladesh) and evaluates…
- Trial name
- NCT04508010
- Testing
- IVR, CATI
- Where
- Bangladesh
- Volunteers
- 6,151 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health