Clinical trials: Non-Pharmacological Interventions
Alzheimer Disease
Neuropsychological and Neurophysiological Effects of Cognitive Stimulation in Patients With Alzheimer's Disease and Mild Cognitive Impairment
The present study aims to evaluate the effect of cognitive stimulation (CS) in participants with a diagnosis of moderate and mild Alzheimer's disease (AD) and mild cognitive impairment (MCI) compared to control subjects not…
- Trial name
- NCT03784183
- Testing
- Cognitive Stimulation (CS)
- Where
- Italy
- Volunteers
- 126 people
- Sponsor
- University of Roma La Sapienza
Labor Pain and Anxiety, Labor Progress
Effects of Dim Light During Labor on Pain, Anxiety, and Labor Progress
The environment of the labor room may influence how women experience childbirth. Light levels, in particular, may affect comfort, stress, and the course of labor.
- Trial name
- DIM-LIGHT (NCT07310602)
- Testing
- Dim Light Exposure During Labor, Routine Labor Room Lighting
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Pınar Erdoğan
Virtual Reality, Pain Management
Surgical Drain Removal: Pain and Anxiety Management
Background: Surgical drain removal may cause pain and anxiety in patients after bariatric surgery. Virtual reality may reduce procedure-related discomfort by directing attention away from painful stimuli.
- Conditions
- Virtual Reality, Pain Management, Pain Management After Surgery, Anxiety After Surgery
- Trial name
- NCT07081425
- Testing
- VRG Group
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Kocaeli University
Chronic Rhinitis, Chronic Pharyngitis
Efficacy and Safety of High-Concentration 35 kDa Hyaluronan Gel for Chronic Nasopharyngitis
This is a prospective, single-arm, open-label, pilot clinical study to evaluate the efficacy and safety of nasopharyngeal administration of 13.6% high-concentration 35 kDa hyaluronan (HA35) care gel in subjects with chronic…
- Conditions
- Chronic Rhinitis, Chronic Pharyngitis, Nasopharyngitis, Posterior Pharyngeal Inflammation
- Trial name
- HA35 (NCT07568548)
- Testing
- 13.6% High-Concentration 35 kDa Hyaluronan (HA35) Nasopharyngeal Care Gel
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Nakhia Impex LLC
Episodic Migraine Headache
Craniocervical Flexion Training for Reducing Migraine Headaches and Disability
Migraine, a leading cause of disability globally, necessitates effective interventions beyond pharmacotherapy due to the associated risks.
- Trial name
- NCT06751732
- Testing
- Craniocervical Flexion Training (CCFT), Diaphragm Respiratory Training, Cervical Mobilization and Traction
- Where
- Pakistan
- Volunteers
- 38 people
- Sponsor
- Riphah International University
Dementia, Agitation
Virtual Reality to Advance Dementia Care and Quality of Life
The goal of this feasibility clinical trial is to learn whether supervised virtual reality (VR) sessions can be safely and practically provided to adults aged 55 years and older with moderate-to-severe dementia who experience…
- Conditions
- Dementia, Agitation, Behavioural and Psychological Symptoms of Dementia, Major Neurocognitive Disorder
- Trial name
- VR-Care (NCT07893678)
- Testing
- Supervised Virtual Reality Sessions
- Where
- 2 sites in Canada
- Volunteers
- 10 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Postoperative Pain Management
Nursing Heat Therapy After Cholecystectomy
This randomized controlled study aims to evaluate the effect of local heat application to the feet on postoperative pain and abdominal distension in patients undergoing open or laparoscopic cholecystectomy.
- Trial name
- nursing (NCT07417319)
- Testing
- Local Heat Application
- Where
- Turkey (Türkiye)
- Volunteers
- 82 people
- Sponsor
- Aydin Adnan Menderes University
Neonatal Opioid Withdrawal Syndrome, Prenatal Opioid Exposure
Recorded Parent/Caregiver Voice for Infants With Neonatal Opioid Withdrawal Syndrome
Neonatal opioid withdrawal syndrome (NOWS) can affect a newborn infant's ability to eat, sleep, and be consoled after exposure to opioids before birth.
- Conditions
- Neonatal Opioid Withdrawal Syndrome, Prenatal Opioid Exposure, Opioid Withdrawal, Neonatal Abstinence Syndrome
- Trial name
- VOICE-NAS (NCT07864493)
- Testing
- Recorded Parent/Caregiver Voice Playback
- Where
- 2 sites in Canada
- Volunteers
- 20 people
- Sponsor
- University of Manitoba
Pain, Analgesia
Non-Pharmacologic Interventions to Relief Pain in Healthy Newborns Submitted to Vaccination to Hepatitis B
Acute procedural pain in neonates may be alleviated by non-pharmacological procedures. This study objective is to test the efficacy regarding pain attenuation of 3 interventions (skin-to-skin contact versus glucose 25% versus…
- Trial name
- NCT00713986
- Testing
- Water 2mL PO 2 minutes prior to intra-muscular injection, skin-to-skin contact, Glucose 25% 2 mL PO 2 minutes prior to injection
- Volunteers
- 640 people
- Sponsor
- Federal University of São Paulo
Burn, Child
Virtual Reality Distraction for Procedural Pain Management and Anxiety in Children With Burn Injuries : A Pilot Study
Procedural pain is the most intense and often undertreated pain associated with burn injuries. The use of analgesics does not always provide optimal relief and is accompanied by several side effects.
- Conditions
- Burn, Child, Pain, Anxiety
- Trial name
- NCT02794103
- Testing
- Virtual Reality Distraction
- Where
- Canada
- Volunteers
- 18 people
- Sponsor
- St. Justine's Hospital
Dementia, Cognitive Dysfunction
Protocolized Receptive Music Intervention to Reduce Care Refusal in Nursing Home Residents With Major Neurocognitive Disorders
The goal of this randomized study is to find out whether using a structured, protocolized music program (MUSIC CARE©) during daily hygiene care can reduce care refusal in older adults with dementia (memory and thinking…
- Conditions
- Dementia, Cognitive Dysfunction, Psychomotor Agitation, Burnout, Professional
- Trial name
- OPPOZIC' (NCT07730957)
- Testing
- Receptive music therapy, Standard Nursing Home Care
- Where
- 12 sites in France
- Volunteers
- 60 people
- Sponsor
- LNA SANTE
Labor, Second Stage of Labor
The Effect of Chocolate Consumption During Labor on Second Stage Duration
Childbirth is an energy-intensive physiological process, requiring sustained effort comparable in intensity to moderate physical activity.
- Conditions
- Labor, Second Stage of Labor, Pregnancy
- Trial name
- NCT07375836
- Testing
- 50 g of milk chocolate cocoa content 25-30%
- Volunteers
- 180 people
- Sponsor
- Hillel Yaffe Medical Center
Cognitive Impairment
Nurse-Led Active Music Program in Older Adults With Cognitive Impairment
This pilot study evaluated the feasibility and acceptability of a structured, nurse-led active music program for older adults with cognitive impairment living in a long-term care facility.
- Trial name
- NCT07831850
- Testing
- Nurse-Led Active Music Program
- Where
- Spain
- Volunteers
- 11 people
- Sponsor
- Universidad de Almeria
Cognitive Impairment
Cost-utility Analysis of the Use of the Paro Robotic Seal by Elderly Patients With Moderate or Severe Cognitive Disorders in Institutions: a Randomised Study.
Many residents from establishments for dependent elderly people (EHPAD) have memory disorders with behavioural problems such as agitation, aggression and anxiety, which make it difficult to assist them on a daily basis.
- Trial name
- PEPINO (NCT04941222)
- Testing
- With robotic seal "PARO"
- Where
- France
- Volunteers
- 33 people
- Sponsor
- Centre Hospitalier Departemental Vendee
Newborn
The Efficacy of Non-pharmacological Interventions on Pain Levels, Crying Times and Voice Decibels in Newborns
This study aimed to investigate and compare the effects of different non-pharmacological interventions (kangaroo care, holding on mother's lap, white noise listening, ambient sound listening) on newborns' crying times, voice…
- Trial name
- NCT04033874
- Testing
- kangaroo care, holding on the mother's lap, white noise listening
- Where
- Turkey (Türkiye)
- Volunteers
- 136 people, healthy volunteers welcome
- Sponsor
- Eskisehir Osmangazi University
Postoperative Delirium
Prevention of Postoperative Delirium After Acute Surgery
The aim of this trial is to evaluate the implementation and effect of an evidence based, multicomponent intervention on postoperative delirium, when fast implemented throughout the patients stay in hospital before, during and…
- Trial name
- POD-CARE (NCT04857125)
- Testing
- Patient interventions, Staff education
- Where
- Denmark
- Volunteers
- 476 people
- Sponsor
- Bispebjerg Hospital
Asthma (Diagnosis)
Changing Lifestyle to Improve Quality of Life in Spanish Adolescents With Asthma
The goal of this clinical trial is to evaluate if a multicomponent lifestyle intervention can improve health-related quality of life in adolescents with asthma.
- Trial name
- CLiQ-Asthma (NCT07870980)
- Testing
- Lifestyle-change intervention
- Volunteers
- 96 people
- Sponsor
- Universitat Internacional de Catalunya
Myasthenia Gravis
Integrating Art Therapy and Adapted Physical Activity: Toward Improved Quality of Life in Patients With Myasthenia Gravis
Myasthenia Gravis (MG) is a rare neuromuscular disease characterized by fluctuating muscle weakness and excessive fatigability. Although medical treatments have improved, MG continues to significantly impact patients' physical…
- Trial name
- APART-MG (NCT07125105)
- Testing
- Adapted Physical Activity Only, Adapted Physical Activity + Art Therapy
- Where
- France
- Volunteers
- 102 people
- Sponsor
- Universite du Littoral Cote d'Opale
Alzheimer's Disease (AD) and Related Disorders
Non-pharmacological Care of Alzheimer's Disease: Benefice of Musical Interventions
Cares of Alzheimer's disease (AD) and related disorders are presenting a real public health challenge. Because of the limited effectiveness of pharmacological treatments, there is a growing interest in care approach based on…
- Trial name
- MusicAlzheimer (NCT02833870)
- Testing
- Musical intervention, Non-musical (cooking) intervention, Control with no intervention
- Where
- France
- Volunteers
- 150 people
- Sponsor
- CHU de Reims
Mood Disorders, Major Depressive Disorder
Immune Activation, Neural Plasticity and Depression
Major depressive disorder (MDD) is a chronic, recurring and potentially life-threatening illness that affects up to 10% of the population across the globe.Increasing evidence indicates a clear link between immune dysfunction and…
- Conditions
- Mood Disorders, Major Depressive Disorder, Sleep Deprivation
- Trial name
- NCT06306248
- Testing
- Total sleep deprivation
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- IRCCS San Raffaele