Clinical trials: Non Celiac Wheat Sensitivity
Non-celiac Gluten Sensitivity, Wheat Intolerance
Bread Study: Comparison of the Tolerance of Spelt and Wheat Bread
This project aims to verify the hypothesis that spelt products are more tolerable than bread wheat products in a target group of individuals with self-diagnosed wheat sensitivity.
- Trial name
- NCT04401956
- Testing
- bread
- Where
- Germany
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Hohenheim
Non-Celiac Wheat Sensitivity
Malnutrition In Non-Celiac Wheat Sensitivity Patients
Non-celiac gluten sensitivity (NCGS) or 'wheat sensitivity' (NCWS) is included in the spectrum of gluten-related disorders. No data are available on the prevalence of low bone mass density (BMD) in NCWS.
- Trial name
- NCT02421796
- Where
- 2 sites in Italy
- Volunteers
- 270 people
- Sponsor
- University of Palermo
Sjogren's Syndrome, Non-celiac Gluten Sensitivity
Wheat-free Diet in the Treatment of Sjogren's Syndrome
Recent data show that some foods can increase intestinal mucosa permeability and immune activation of subjects with gastrointestinal (GI) symptoms.
- Trial name
- NCT05644795
- Testing
- Wheat/milk free diet (W/MFD) group, Rice/turkey free diet (R/TFD) group
- Where
- 3 sites in Italy
- Volunteers
- 30 people
- Sponsor
- University of Palermo
Celiac Disease, Wheat Hypersensitivity
Changes in Intestinal Permeability 4 Hours After Gluten Challenge
This study evaluates why people with celiac disease and non-celiac gluten/wheat sensitivity develop rapid onset symptoms within hours of gluten exposure. Half of subjects will be given gluten and half will not.
- Conditions
- Celiac Disease, Wheat Hypersensitivity, Gluten Sensitivity, Gluten Enteropathy
- Trial name
- NCT03288831
- Testing
- Gluten
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Non-celiac Gluten/Wheat Sensitivity
Urinary Gluten Immunogenic Peptides Detection in Non-celiac Gluten/Wheat Sensitivity
Non-celiac gluten/wheat sensitivity (NCGS/NCWS) is a syndrome characterized by both intestinal (irritable bowel syndrome [IBS]-like presentation) and extraintestinal symptoms (headache, migraine, "foggy mind", depression…
- Trial name
- NCT04219813
- Testing
- Urinary test
- Where
- 2 sites in Italy
- Volunteers
- 40 people
- Sponsor
- University of Palermo
Non-celiac Gluten Sensitivity
Extraintestinal Non Celiac Wheat Sensitivity
Non Celiac Gluten Sensitivity (NCGS), or, better, Non Celiac Wheat Sensitivity (NCWS), since it is not known the real pathogenetic component(s) of grain, is a syndrome characterized by a cohort of symptoms, both gastrointestinal…
- Trial name
- NCT04769180
- Testing
- Evaluation of extraintestinal manifestations
- Where
- 2 sites in Italy
- Volunteers
- 200 people
- Sponsor
- University of Palermo
Non-celiac Wheat Sensitivity
Osteoporosis In Non-Celiac Wheat Sensitivity Patients
Non-celiac gluten sensitivity (NCGS) or 'wheat sensitivity' (NCWS) is included in the spectrum of gluten-related disorders. No data are available on the prevalence of low bone mass density (BMD) in NCWS.
- Trial name
- NCT02421783
- Where
- 2 sites in Italy
- Volunteers
- 270 people
- Sponsor
- University of Palermo
Non-celiac Wheat Sensitivity
Oral Lesions In Non-Celiac Wheat Sensitivity Patients
Non-celiac gluten sensitivity (NCGS) or 'wheat sensitivity' (NCWS) is included in the spectrum of gluten-related disorders. No data are available on the prevalence of oral lesions in NCWS.
- Trial name
- NCT02421809
- Where
- 2 sites in Italy
- Volunteers
- 270 people
- Sponsor
- University of Palermo
Non-celiac Wheat Sensitivity
Response to Different Wheat Genotypes in Not-celiac Wheat Sensitivity
Non-celiac gluten sensitivity (NCGS) is a condition where intestinal and extraintestinal symptoms are triggered by gluten ingestion in the absence of celiac disease and wheat allergy.
- Trial name
- NCT03024775
- Testing
- Wheat flour
- Where
- 2 sites in Italy
- Volunteers
- 50 people
- Sponsor
- University of Palermo
Non Celiac Wheat Sensitivity
Nickel Allergy and Systemic Nickel Allergy Syndrome in Non Celiac Wheat Sensitivity
In the last few years, a new clinical entity has emerged which includes patients who consider themselves to be suffering from problems caused by wheat and/or gluten ingestion, even though they do not have celiac disease (CD) or…
- Trial name
- NCT02750735
- Where
- 2 sites in Italy
- Volunteers
- 200 people
- Sponsor
- University of Palermo
Non-celiac Wheat Sensitivity
Self-reported Gluten Sensitivity in High-school Students
It has been reported that a consistent percentage of the general population consider themselves to be suffering from problems caused by wheat and/or gluten ingestion, even though they do not have celiac disease or wheat allergy.
- Trial name
- NCT03021148
- Testing
- Questionnaire
- Where
- 2 sites in Italy
- Volunteers
- 500 people
- Sponsor
- University of Palermo
Non-celiac Wheat Sensitivity
KIR Genes and Non-Celiac Wheat Sensitivity
Non-celiac gluten sensitivity (NCGS) is a condition characterized by gastrointestinal and extraintestinal symptoms which are triggered by gluten ingestion in the absence of celiac disease (CD) and wheat allergy.
- Trial name
- NCT05469971
- Testing
- KIR genotyping
- Where
- 4 sites in Italy
- Volunteers
- 170 people
- Sponsor
- University of Palermo
Non-celiac Wheat Sensitivity
Abdominal Ultrasound Examination in Non-celiac Wheat Sensitivity
Recently it has been reported that a consistent percentage of the general population consider themselves to be suffering from problems caused by wheat and/or gluten ingestion, even though they do not have CD or wheat allergy.
- Trial name
- NCT03017274
- Testing
- Abdominal ultrasound examination
- Where
- 2 sites in Italy
- Volunteers
- 100 people
- Sponsor
- University of Palermo
Gluten Sensitivity, Wheat Sensitivity
Effects of a Probiotic Supplementation on Symptoms and Microbiome Characteristics in Patients With Non-celiac Gluten/Wheat Sensitivity.
The aim of this randomized, double-blind, placebo-controlled clinical trial is to investigate the effects of probiotics on symptoms and gut microbiota composition following gluten reintroduction.
- Trial name
- NCT06884241
- Testing
- Probiotic supplementation
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- University of Turin, Italy
Non-celiac Gluten Sensitivity, Wheat Hypersensitivity
Wheat Bread Study: Comparison of the Tolerance of Different Wheat Breads
This study aims to assess the differences in tolerability of differently manufactured wheat breads in a target group of individuals with suspected wheat sensitivity.
- Trial name
- NCT06152445
- Testing
- Wheat bread
- Where
- 2 sites in Germany
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- University of Hohenheim
Non-Celiac Wheat Sensitivity
Autoimmune Diseases And Serum Anti-Nuclear Antibodies Positivity In Non-Celiac Wheat Sensitivity Patients
Celiac disease (CD) is an immune-based reaction to dietary gluten (storage protein for wheat, barley, and rye) that primarily affects the small intestine in genetically predisposed patients and resolves with exclusion of gluten…
- Trial name
- NCT02248545
- Where
- 3 sites in Italy
- Volunteers
- 90 people
- Sponsor
- University of Palermo
Inflammatory Back Pain
Inflammatory Back Pain and Gluten Free Diet
Articular involvement is the most frequent extra-intestinal manifestation of inflammatory bowel diseases (IBD). IBD-related spondyloarthropathy is mainly characterised by axial involvement (including inflammatory back pain…
- Trial name
- NCT03017716
- Testing
- Gluten free diet
- Where
- 2 sites in Italy
- Volunteers
- 50 people
- Sponsor
- University of Palermo
Non-celiac Gluten Sensitivity
Tolerability of an Ancient Grain in Patients With Non-Celiac Wheat Sensitivity
Patients suffering from wheat-related troubles, in absence of celiac disease or wheat allergy diagnosis, can suffer from non-celiac wheat sensitivity (NCWS).
- Trial name
- NCT06191432
- Testing
- Administration of Triticum Monococcum flour, Administration of Triticum Aestivum flour
- Where
- Italy
- Volunteers
- 68 people
- Sponsor
- University of Palermo
Non-celiac Wheat Sensitivity
Gynaecological Disorders in Not-celiac Wheat Sensitivity
In the last few years, a new clinical entity has emerged which includes patients who consider themselves to be suffering from problems caused by wheat and/or gluten ingestion, even though they do not have celiac disease (CD) or…
- Trial name
- NCT03027492
- Testing
- Gluten free diet, NCWS open challenge with wheat
- Where
- 3 sites in Italy
- Volunteers
- 500 people
- Sponsor
- University of Palermo
Non Celiac Wheat Sensitivity, IBS (Irritable Bowel Syndrome)
NCWS or IBS/FD in Relatives of CD Patients
Over 50% of non-celiac wheat sensitivity (NCWS) patients are HLA DQ2/DQ8 positive and often have a Celiac Disease (CD) family history.
- Conditions
- Non Celiac Wheat Sensitivity, IBS (Irritable Bowel Syndrome), Functional Dyspepsia, Celiac Disease
- Trial name
- NCT07584473
- Testing
- Wheat-Free Diet
- Where
- 2 sites in Italy
- Volunteers
- 600 people
- Sponsor
- University of Palermo