Clinical trials: Neuropsychological Tests
Multiple Sclerosis
Psychometric Validation of Cognitive Endpoints
The study will entail cognitive assessment of a single cohort of patients with Multiple Sclerosis. Each subject will be assessed twice, approximately 45 days apart. There will be no intervention or control group.
- Trial name
- NCT01335633
- Where
- 4 sites in United States
- Volunteers
- 60 people
- Sponsor
- Kessler Foundation
Drepanocytosis, Chronic Neurological Deficiency
Transfusion Exchanges and Cognition in Sickle Cell Disease
DREPA-COG is an observational study evaluating the effect of exchange transfusions on cognitive function in adults with severe sickle cell disease (SS or Sβ0).
- Trial name
- DREPA-COG (NCT07168447)
- Where
- 6 sites in France
- Volunteers
- 85 people
- Sponsor
- Centre Hospitalier St Anne
Mild Cognitive Impairment (MCI), Subjective Cognitive Decline (SCD)
LETHE-AT: a Personalized Multidomain Lifestyle Intervention for Individuals at Increased Risk of Memory Impairment.
The goal of this clinical trial is to learn whether a hybrid multidomain lifestyle program can prevent cognitive decline and reduce dementia risk in community-dwelling adults in mid- to late life who are at increased risk of…
- Trial name
- LETHE-AT (NCT07376135)
- Testing
- A tailored hybrid multidomain lifestyle intervention group, Self-guided multimodal lifestyle advice group
- Where
- 3 sites in Austria
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Phenylketonuria
The Effect of Supplemental Docosahexaenoic Acid (DHA) on Neurocognitive Outcomes in Teen and Adult Women With Phenylketonuria(PKU)
The purpose of this study is to determine if taking supplemental DHA improves measures of processing speed and executive function in teen and adult women with PKU.
- Trial name
- PKU&DHA (NCT00892554)
- Testing
- Docosahexaenoic Acid, Corn/soy oil
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- Emory University
Anterior Temporal Epilepsy, Anterior Temporal Lobectomy
Anterior Temporal Epilepsy Neuropsychological Assessment of Faces
The purpose is to evaluate neuropsychological effects of anterior temporal epilepsy in face perception by comparison of performances of epileptic patients and control individuals, sex-, age- and socio-educational level-matched.
- Conditions
- Anterior Temporal Epilepsy, Anterior Temporal Lobectomy, Face Perception
- Trial name
- ATENA-F (NCT02888925)
- Testing
- Mooney test, Benton Face Recognition test, Face inversion effect test
- Where
- France
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Central Hospital, Nancy, France
Brain Damage, Health Behavior
A Neuropsychological Test Battery for the Assessment of Time Deficits
Time processing involves different abilities - i.e. estimating the duration of an event and moving in past and future time - and it is a fundamental ability in everyday life.
- Trial name
- NCT04419818
- Testing
- Virtual Reality
- Where
- Italy
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Istituti Clinici Scientifici Maugeri SpA
HIV Infections, Central Nervous System Diseases
Clinical Trial of Brain-Penetrating HIV Drugs to Prevent Cognitive Impairment in China
This primary aim of the project is to determine the association between antiretroviral therapy that better distributes into the central nervous system and prevention of HIV-associated neurocognitive impairment.
- Conditions
- HIV Infections, Central Nervous System Diseases, Dementia
- Trial name
- NCT01340950
- Testing
- zidovudine-lamivudine-nevirapine, tenofovir-lamivudine-efavirenz
- Where
- 2 sites in China
- Volunteers
- 250 people
- Sponsor
- University of California, San Diego
Schizophrenic Disorders
Neuropsychological Assessment of Remediation for Cognitive Impairments in Schizophrenia
This study evaluates the effect of a cognitive remediation program on neurocognitive, social cognitive and metacognitive functions designed for patients living with a schizophrenia spectrum disorder.
- Trial name
- NARCIS (NCT04608032)
- Testing
- [Eco-Sz] Ecological Cognitive training program for schizophrenia spectrum disorder, Recovery-Oriented Therapy
- Where
- 2 sites in France
- Volunteers
- 70 people
- Sponsor
- Centre hospitalier de Ville-Evrard, France
Multiple Sclerosis, Cognition Disorders
Trial of Memantine for Cognitive Impairment in Multiple Sclerosis
This study is designed to determine whether memantine is an effective treatment for memory and cognitive problems associated with multiple sclerosis when compared to placebo.
- Trial name
- NCT00300716
- Testing
- Memantine
- Where
- 4 sites in United States
- Volunteers
- 82 people
- Sponsor
- Oregon Health and Science University
Alzheimer Disease, Memory Disorders
Virtual Reality Cognitive Stimulation for Alzheimer's
This study aims to evaluate whether immersive virtual reality (VR) can improve cognitive function and memory in patients with Alzheimer's disease.
- Trial name
- CODDI (NCT07645638)
- Testing
- Virtual reality
- Where
- Spain
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Universidad de Burgos
Cerebral Neurological Illness
Pilot Study of New Computer-based Neuropsychological Tool: Visual Tests, Touch Responses
This study is aimed at investigating three new tests that will form part of a computerized tool designed to test brain/cognitive functioning.
- Trial name
- NCT03502603
- Testing
- Railroad Test, Swamp Test, Presidents Recognition Test
- Where
- United States
- Volunteers
- 137 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Cognitive Benefits
Citicoline, Creatine, and Omega-3 Effects in Middle Age Women
The purpose of this study is to determine the functional effects of a citicoline, creatine, and omega-3 fatty acids combination when administered for a duration of four weeks (28 days) to non-psychiatric adult female participants.
- Trial name
- NCT01502813
- Testing
- Citicoline, Omega-3 Fatty Acids and Creatine
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Deborah Yurgelun-Todd
Traumatic Brain Injury, Trauma
The Effect of Mild Traumatic Brain Injury on Recovery From Injury
Mild traumatic brain injury (TBI) is a common injury that can produce significant functional sequelae and ongoing disabling symptoms.
- Conditions
- Traumatic Brain Injury, Trauma, Head Injury, Brain Concussion
- Trial name
- NCT00295074
- Testing
- neuropsychologic testing
- Where
- United States
- Volunteers
- 800 people
- Sponsor
- University of Pittsburgh
Postoperative Cognitive Dysfunction
Post Cardiac Surgery Neurocognitive Decline: Correlations Between Neuropsychological Tests and Functional MRI Techniques
Postoperative cognitive decline (POCD) is a frequent complication after cardiac surgery. It is estimated that 40-70% of all cardiac patients show cognitive dysfunction during the first post-surgical week.
- Trial name
- CardChNeuroMRI (NCT01622452)
- Volunteers
- 50 people
- Sponsor
- Fondazione Toscana Gabriele Monasterio
COVID-19
A Two Year Longitudinal Clinical Study of Neurocognitive and Psychiatric Symptoms in Post COVID-19 Patients
The prospective, longitudinal, open observational study monitors patients with cognitive and neuropsychological symptoms after COVID-19 infection, in a longitudinal manner to see how the disease has affected their physical…
- Trial name
- PASC24 (NCT06298006)
- Testing
- Follow-up
- Where
- Sweden
- Volunteers
- 57 people
- Sponsor
- Region Örebro County
Alzheimer Disease, Parkinson Disease
The Relationship Between Neuropsychological Testing and MRI, PET and COBRE - Project 1: AIM 2 (GE-180)
The complex pathological cascades leading to both Alzheimer's disease (AD) and Parkinson's disease (PD) involve, at various points, inflammation.
- Conditions
- Alzheimer Disease, Parkinson Disease, Inflammation
- Trial name
- NCT03702816
- Testing
- GE180 PET Scan
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Aaron Ritter, MD
COVID-19, Long Haul
Digital Cognition Study During Long-COVID
The persistence of the COVID-19 disease symptoms, such as extreme fatigue, shortness of breath, cardiovascular complications, depression and anxiety, pain, brain fog, loss of taste/smell, headaches as well as loss of memory has…
- Trial name
- DIGICOG (NCT06391970)
- Testing
- Cognitive screening
- Where
- Luxembourg
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Luxembourg Institute of Health
Neurodegenerative Diseases, Cognition Disorders in Old Age
Probiotics in Mild Alzheimer's Disease
The main objective is to investigate whether administration of probiotics to patients with mild Alzheimer's Disease (AD) reduces neuroinflammation, improves cognitive function and modifies neurophysiological measures, compared to…
- Trial name
- NCT06181513
- Testing
- Probiotic Blend Capsule
- Where
- Cyprus
- Volunteers
- 40 people
- Sponsor
- University of Nicosia
Acute Stress Reaction
The Efficacy of Vitamin D Supplementation to Sustain Performance Outcomes
The goal of this clinical trial is to find out if vitamin D supplements help healthy adults maintain their cognitive and simple physical task performance and emotional state during highly stressful situations.
- Trial name
- NCT07654777
- Testing
- Vitamin D3 (Cholecalciferol)
- Where
- United States
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Walter Reed Army Institute of Research (WRAIR)
Feeding and Eating Disorders, Anorexia Nervosa
Cognitive Training for Patients With Eating Disorders
Eating disorders are severe mental illnesses, mainly affecting adolescent- and young adult women. The prognoses for eating disorders are relatively poor, and a large part of patients with these illnesses do not benefit from…
- Conditions
- Feeding and Eating Disorders, Anorexia Nervosa, Bulimia Nervosa, Binge-Eating Disorder
- Trial name
- TCRTRCT (NCT03808467)
- Testing
- Cognitive Remediation Therapy, Treatment as usual
- Where
- 3 sites in Norway
- Volunteers
- 100 people
- Sponsor
- Norwegian University of Science and Technology