Clinical trials: Neuropathy, open to volunteers
Carpal Tunnel Syndrome (CTS)
Pulsed Radiofrequency Versus Hyaluronidase Hydrodissection for Treatment of Carpal Tunnel Syndrome
The aim of this study is to compare the clinical efficacy and safety of ultrasound-guided pulsed radiofrequency and hyaluronidase hydrodissection in the treatment of carpal tunnel syndrome.
- Trial name
- NCT07269613
- Testing
- Pulsed Radiofrequency, Hyaluronidase Hydrodissection
- Where
- Egypt
- Volunteers
- 56 people
- Sponsor
- Sohag University
Ischemic Heart Disease, Nerve Injury
Association Between Radial Artery Intervention and Development of Neuropathy in the Hand - A Prospective Study
Evaluation of potential nerve damage after radial CAG/PCI.
- Conditions
- Ischemic Heart Disease, Nerve Injury, Carpal Tunnel Syndrome
- Trial name
- ACCESS-IV (NCT05365282)
- Where
- Denmark
- Volunteers
- 400 people
- Sponsor
- Aarhus University Hospital Skejby
Chronic Kidney Disease Stage 3 and 4, Diabetes
Prediction of Peripheral Neuropathy With Functional Testing
Diabetes and chronic kidney disease (CKD) are two distinct pathologies. The former is defined as an impairment in insulin production and/or utilization, while the latter refers to structural or functional abnormalities of the…
- Trial name
- PredictNP (NCT06933108)
- Where
- France
- Volunteers
- 70 people
- Sponsor
- Université catholique de l'Ouest
Carpal Tunnel Syndrome
Thenar Muscle Ultrasound in CTS Evaluation
This study will include 20 patients aged 18-75 years who have been diagnosed with carpal tunnel syndrome (CTS) based on electrophysiological examinations performed within the last three months, as well as 20 healthy volunteers…
- Trial name
- NCT06730724
- Testing
- No intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Beylikduzu State Hospital
Chemotherapy
A Stuty on the Treatment and Nursing Care of CIPN Patients With Traditional Chinese Medicine Hot Package
The combination of platinum and taxane drugs has a chemotherapy-induced peripheral neuropathy (CIPN) rate of 73% to 83%. Its symptoms can not only limit daily activities and cause a variety of accidental injuries, but also easily…
- Trial name
- NCT06492083
- Testing
- traditional Chinese medicine hot bag
- Where
- China
- Volunteers
- 90 people
- Sponsor
- The Fourth Affiliated Hospital of Zhejiang University School of Medicine
Carpal Tunnel Syndrome (CTS)
Comparison of Rest Splints vs High-Intensity Laser Therapy in Carpal Tunnel Syndrome
The aim of this study is to compare the effectiveness of rest splints and high-intensity laser therapy(HILT) added to physical therapy programs for patients with carpal tunnel syndrome in terms of pain, function, nerve conduction…
- Trial name
- NCT07294157
- Testing
- Rest splint group, high-intensity laser therapy (HILT)
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 78 people
- Sponsor
- Afyonkarahisar Health Sciences University
Acute Lymphoblastic Leukemia ALL
Tracjectories and Predictors of Chemotherapy Induced Peripheral Neuropathy in Children With Acute Lymphoblastic Leukemia
The goal of this study is to explore the trajectory patterns of chemotherapy induced peripheral neuropathy over the course of chemotherapy and identify predictors of distinct trajectories in children with acute lymphoblastic…
- Trial name
- NCT07326930
- Where
- 3 sites in China
- Volunteers
- 173 people
- Sponsor
- The Hong Kong Polytechnic University
Carpal Tunnel Syndrome, Median Neuropathy
Hydrodissection With Neuroprolotherapy Versus Open Release for Carpal Tunnel Syndrome
This study is a randomized controlled, parallel-group, non-inferiority trial designed to compare ultrasound-guided hydrodissection combined with neuroprolotherapy versus open carpal tunnel release in patients with carpal tunnel…
- Trial name
- HN-CTS (NCT07576803)
- Testing
- Ultrasound-guided Hydrodissection of the Median Nerve, Open Carpal Tunnel Release
- Where
- Brazil
- Volunteers
- 72 people
- Sponsor
- Universidade Federal de Pernambuco
Carpal Tunnel Syndrome, Wound Infection
abSorbable vErsus Non-absorbable SuturEs for Wound Closure in Carpal Tunnel Release
Carpal Tunnel Syndrome is a prevalent condition, up to 9% in women and 0.6% in men. Surgical decompression in the most effective treatment. After surgery, approximately 1,8% of the patients develop a wound infection.
- Conditions
- Carpal Tunnel Syndrome, Wound Infection, Suture, Complication
- Trial name
- SENSE (NCT05431101)
- Testing
- Carpal Tunnel Release
- Where
- 2 sites in Netherlands
- Volunteers
- 2,604 people, healthy volunteers welcome
- Sponsor
- Gelre Hospitals
Diabetic Foot, DFU
Trial Assessing the Efficacy of Human Placental Membrane Products and Standard of Care Versus Standard of Care Alone in the Management of Nonhealing Diabetic Foot Ulcers and Venous Leg Ulcers
The purpose of this study is to evaluate the efficacy of human placental membrane products and standard of care versus standard of care alone in the management of nonhealing diabetic foot ulcers and venous leg ulcers.
- Conditions
- Diabetic Foot, DFU, Diabetic Foot Ulcer, Foot Ulcer, Diabetic
- Trial name
- BIOCAMP (NCT07089602)
- Testing
- Standard of Care DFU, Tri-Membrane Wrap™ DFU, Membrane Wrap™ DFU
- Where
- United States
- Volunteers
- 650 people
- Sponsor
- BioLab Holdings
Low Back Pain, Mechanical, Piriformis Syndrome
Strain-Counterstrain Treatment of Piriformis Pain
The purpose of this investigator-initiated study is to provide an efficient and non-invasive treatment option for pain caused by the piriformis muscle.
- Conditions
- Low Back Pain, Mechanical, Piriformis Syndrome, Somatic Dysfunction of Sacral Region (Finding)
- Trial name
- NCT05023005
- Testing
- Strain-Counterstrain treatment of piriformis muscle
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Loma Linda University
Peripheral Neuropathy, Multiple Myeloma, Neoplasms
Fenofibrate Role in the Prophylaxis From Peripheral Neuropathy Induced by Bortezomib, Lenalidomide and Dexamethasone (VRd) Protocol in the Treatment of Patients With Multiple Myeloma (MM)
This study aims at evaluating the possible beneficial role of Fenofibrate in attenuating the peripheral neuropathy associated with bortezomib (velcade), lenalidomide (revlimid), and dexamethasone (VRd) regimen in newly diagnosed…
- Trial name
- VRd MM Fibrate (NCT07025005)
- Testing
- Bortezomib + Lenalidomide + Dexamethasone + Fenofibrate 160 mg tablet, Bortezomib + Lenalidomide + Dexamethasone
- Where
- 2 sites in Egypt
- Volunteers
- 44 people
- Sponsor
- Tanta University
Neuro-Ophthalmology, Optic Neuropathies
Optic Nerve Head Evaluation Through Multimodal Blood Flow Analysis: a Prospective Observational, Multi-center Study
OCT-A and eco-colordoppler are technologies which enable optic nerve head (ONH) blood perfusion detection. The aim of the study is to assess ONH vascular and structural components in optic neuropathies with and without ONH edema…
- Conditions
- Neuro-Ophthalmology, Optic Neuropathies, Optic Atrophy, Hereditary, Leber, Optic Neuropathy, Anterior Ischemic
- Trial name
- FlowONH (NCT07075887)
- Volunteers
- 70 people
- Sponsor
- Barboni
Muscular Dystrophies, Myopathies
Observational Study to Observe Variations of Gait Parameters in Patients With Neuromuscular Diseases
This study has the general objective of observing walking parameters during a clinical test to objectively estimate fatigue in patients with neuromuscular diseases.
- Conditions
- Muscular Dystrophies, Myopathies, Spinal Muscular Atrophy (SMA), Charcot Marie Tooth Disease
- Trial name
- NCT06666816
- Testing
- inapplicable
- Where
- 2 sites in Italy
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- IRCCS Eugenio Medea
Cerebellar Ataxia, Neuropathy
Evaluation of Urinary Dysfunction in CANVAS Patients
The investigator wishes to evaluate the prevalence of urinary symptoms in patients diagnosed with Cerebellar Ataxia, Neuropathy, Vestibular Areflexia Syndrome (CANVAS).
- Conditions
- Cerebellar Ataxia, Neuropathy, Vestibular Areflexia
- Trial name
- UROCANVAS (NCT06817707)
- Testing
- Evaluation of urinary dysfunction in patients with CANVAS
- Where
- 3 sites in France
- Volunteers
- 40 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Charcot-Marie-Tooth Disease
A Registered Cohort Study on Charcot-Marie-Tooth Disease
The aim of the study is to analyze the natural history data data from Charcot-Marie-Tooth disease and related disorders in China, to assess the clinical, genetic, epigenetic features of patients with Charcot-Marie-Tooth disease…
- Trial name
- NCT04010188
- Where
- China
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Ning Wang, MD., PhD.
Diabetic Foot Ulcer (DFU)
The Effects of Bromelain Supplement in Patients with Diabetic Foot Ulcers
This study will be conducted on people over 18 with diabetic foot ulcers.. The first group will receive the standard treatment along with bromelain supplement and the second group will receive the standard treatment and placebo.
- Trial name
- NCT06786403
- Testing
- Bromelain
- Where
- Iran
- Volunteers
- 70 people
- Sponsor
- Dr Azita Hekmatdoost
Diabetic Peripheral Neuropathic Pain
Evaluation of Efficacy and Safety of VX-993 for Pain Associated With Diabetic Peripheral Neuropathy
The purpose of this study is to evaluate the efficacy, safety, and tolerability of VX-993 in participants with pain associated with Diabetic Peripheral Neuropathy (DPN)
- Trial name
- NCT06619860
- Testing
- VX-993, Pregabalin
- Where
- 47 sites in United States, Canada and 4 more
- Volunteers
- 300 people
- Sponsor
- Vertex Pharmaceuticals Incorporated
Diabetes Mellitus, Diabetic Foot Ulcer (DFU)
Risk Perception Intervention for High-Risk Diabetic Foot
This study aims to evaluate the effect of health education based on information framing effects on foot ulcer risk perception in patients at high risk of diabetic foot.
- Conditions
- Diabetes Mellitus, Diabetic Foot Ulcer (DFU), Risk Perception, Peripheral Neuropathy With Type 2 Diabetes
- Trial name
- NCT07581262
- Testing
- Gain-Framed, Loss-Framed, Routine Care
- Volunteers
- 90 people
- Sponsor
- The Third Affiliated Hospital of Soochow University
Head and Neck (HNSCC), Head and Neck Squamous Cell Carcinoma (HNSCC) - Recurrent/Metastatic (R/M)
Aspirin and PAClitaxel in Head & Neck Squamous Cell Carcinoma
This is a phase II trial of aspirin and paclitaxel in patients with recurrent/metastatic (R/M) Head and Neck Squamous Cell Carcinoma (HNSCC) who have received prior platinum and PD-1 inhibitor treatment and have an alteration in…
- Conditions
- Head and Neck (HNSCC), Head and Neck Squamous Cell Carcinoma (HNSCC) - Recurrent/Metastatic (R/M), Head and Neck Squamous Cell Carcinoma, Recurrent / Metastatic Head and Neck Squamous Cell Carcinoma
- Trial name
- APAC (NCT07901803)
- Testing
- Aspirin, Paclitaxel
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Washington University School of Medicine