Clinical trials: Neuromuscular Blockade
Residual Neuromuscular Block, Cardiovascular Diseases
Effects of Low-pressure Pneumoperitoneum Associated With Deep Pipecuronium-induced Neuromuscular Blockade on Hemodynamic Parameters for High Cardiovascular Risk Patient Undergoing General Anesthesia
Deep neuromuscular block (DNMB) during laparoscopy induces less haemodynamic stress by facilitating low-pressure pneumoperitoneum.
- Conditions
- Residual Neuromuscular Block, Cardiovascular Diseases, Neuromuscular Blockade Monitoring
- Trial name
- NCT06517524
- Where
- Hungary
- Volunteers
- 10 people
- Sponsor
- Tamas Vegh, MD
Posterior Cervical Decompression and Fusion
A Randomized Controlled Crossover Study Comparing Sugammadex and Placebo
Intraoperative monitoring of the motor evoked potentials has been shown to be both a sensitive and specific indicator for detecting intraoperative neurological injuries during spine surgery.(Fehlings, Brodke et al.
- Trial name
- NCT03087513
- Testing
- Sugammadex Injection [Bridion]
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- University Health Network, Toronto
Obstructive Sleep Apnea Syndrome
The Effect of Intubation Without Muscle Relaxation on Post Operative Recovery Conditions: Double Blind Randomized Controlled Study
The primary aim of this study is to research the effect of intubation without muscle relaxant on post-operative recovery conditions in patients with OSAS (obstructive sleep apnea syndrome).
- Trial name
- NCT03824470
- Volunteers
- 90 people
- Sponsor
- Yuzuncu Yil University
Neuromuscular Blockade
Electromyographic Assessment of the TetraGraph in Normal Volunteers
There is an urgent need for an easy-to-use and accurate quantitative neuromuscular monitor in the clinical setting. The aim of this clinical investigation is to examine a prototype of a quantitative monitoring instrument that…
- Trial name
- NCT02912039
- Testing
- TetraGraph, TOF Watch
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Anesthesia Recovery Period, Neuromuscular Blockade
The Dose of Sugammadex for Rapid Reversal of Profound Neuromuscular Block in Young and Elderly Patients
To find out the dose of sugammadex for recovery of the TOF ratio to 0.9 within 2 minutes from profound rocuronium-induced neuromuscular block in young and elderly adult patients.
- Trial name
- NCT01890057
- Testing
- Sugammadex
- Where
- South Korea
- Volunteers
- 44 people
- Sponsor
- Severance Hospital
Leiomyoma, Uterine, Benign Gynecological Disease
Deep Neuromuscular Blockade and a Low-Residue Diet for the Surgical Field in vNOTES Hysterectomy
vNOTES (vaginal natural orifice transluminal endoscopic surgery) hysterectomy is performed entirely through the vagina, with no abdominal incision.
- Conditions
- Leiomyoma, Uterine, Benign Gynecological Disease, Abnormal Uterine Bleeding (AUB), Uterine Prolapse
- Trial name
- vNOTES_NMBDIET (NCT07730970)
- Testing
- Deep Neuromuscular Blockade (NMB), Standard (moderate) neuromuscular blockade, Preoperative low-residue diet
- Where
- 3 sites in Turkey (Türkiye)
- Volunteers
- 160 people
- Sponsor
- Fatih Sultan Mehmet Training and Research Hospital
Post-stroke Upper Limb Spasticity
Comprehensive Protocol for Treatment of Upper Limb Spasticity in Post-stroke Hemiplegic Patients
The general objective of this study was to evaluate the efficacy of the comprehensive protocol in improving post-stroke upper limb spasticity.
- Trial name
- NCT05940805
- Testing
- Low-frequency transcranial electrical stimulation; Paraspinous block; Dry needling of spastic upper limb muscles; Muscular functional electrical stimulation (FES)
- Where
- Brazil
- Volunteers
- 32 people
- Sponsor
- University of Sao Paulo General Hospital
Pain, Neuropathic
Stellate Ganglion Block in Herpes Zoster
Patient who will be presented to Tanta University Hospitals complaining of acute herpes zoster with onset of vesicular eruption less than 7 days will be included in this clinical study.
- Trial name
- NCT04188327
- Testing
- Stellate ganglion block
- Where
- 3 sites in Egypt
- Volunteers
- 208 people
- Sponsor
- Tanta University
Airway Management, Neuromuscular Blockade
Effect of Neuromuscular Blockade on Video Laryngeal Mask Airway Ventilation
This prospective, randomized, double-blind study aims to evaluate the effect of different degrees of neuromuscular blockade on the performance of a video laryngeal mask airway (LMA) during general anesthesia.
- Conditions
- Airway Management, Neuromuscular Blockade, General Anesthesia
- Trial name
- NCT07828977
- Testing
- Normal Saline (Rocuronium 0 mg/kg), Rocuronium 0.3 mg/kg, Rocuronium 0.6 mg/kg
- Volunteers
- 96 people
- Sponsor
- Korea University Guro Hospital
Complex Regional Pain Syndromes
Impact of the Ultrasound-guided Approach on the Efficiency and Safety of the Stellate Ganglion Block in Chronic Pain
The first purpose of this study is to compare the effectiveness of the stellate ganglion block realized with two different approaches (blind and ultrasound-guided) in patients with a diagnosis of complex regional pain syndrome.
- Trial name
- NCT01954888
- Testing
- Blind technique, Ultrasound-guided technique
- Where
- Canada
- Volunteers
- 3 people
- Sponsor
- Maisonneuve-Rosemont Hospital
Forward Head Posture
Impact of Adding Integrated Neuromuscular Inhibition Technique to Mulligan Therapy in Symptomatic Forward Head Posture
this study will be conducted to investigate the impact of adding integrated neuromuscular inhibition technique to mulligan therapy in symptomatic forward head posture.
- Trial name
- FHP (NCT07086872)
- Testing
- Integrated Neuromuscular Inhibition Technique and mulligan therapy, Integrated Neuromuscular Inhibition Technique, mulligan therapy
- Volunteers
- 120 people
- Sponsor
- Cairo University
Carpal Tunnel Syndrome (CTS)
Combined Stellate Ganglion Block With Median Nerve Hydrodissection Versus Median Nerve Hydrodissection Only in Carpal Tunnel Syndrome
the study aims to compare clinical and electrophysiological outcomes of combined stellate ganglion block plus median nerve hydrodissection versus hydrodissection alone in carpal tunnel syndrome, assessing pain, function…
- Trial name
- NCT07839611
- Testing
- combined stellate ganglion block procedure and median nerve hydrodissection, Ultrasound-Guided Median Nerve Hydrodissection Procedure only
- Volunteers
- 80 people
- Sponsor
- Fayoum University
Neuromuscular Blockade
Prediction of the Recovery of Neuromuscular Transmission After Curarization
The vast majority of patients receive neuromuscular blockers during surgical procedures, either as a single injection to facilitate intubation or as repeated injections to induce muscle relaxation necessary for surgery.
- Trial name
- NCT03550664
- Testing
- Monitoring of neuromuscular transmission
- Where
- Belgium
- Volunteers
- 100 people
- Sponsor
- Brugmann University Hospital
Sleep Disturbance in Athletes
Effectiveness of Progressive Muscle Relaxation on Sleep Disturbance in Athletes
Literature supports that athletes have so many reasons for sleep disturbance in their day to day practice and during competition.
- Trial name
- NCT05695092
- Testing
- Progressive muscle relaxation, control
- Where
- Pakistan
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Efficacy and Safety of Mivacurium Chloride for Pediatric Patients
A Prospective, Multi-center, Randomized Controlled Study of Muscle Relaxation Effect and Safety of Mivacurium Chloride in Pediatric Surgery Patients
To evaluate the effect and safety of mivacurium chloride in pediatric patients.
- Trial name
- NCT02117401
- Testing
- mivacurium chloride, midazolam, ketamine
- Volunteers
- 1,152 people
- Sponsor
- Jiangsu Nhwa Pharmaceutical Co., Ltd.
Postoperative Gastrointestinal Dysfunction (POGD), Postoperative Ileus
Neuromuscular Blocking Agents on Gastrointestinal Function Following Colorectal Surgery
This study is a clinical research project conducted at Xijing Hospital to compare the effects of two different neuromuscular blockade reversal strategies on the recovery of gastrointestinal (GI) function after colorectal surgery.
- Conditions
- Postoperative Gastrointestinal Dysfunction (POGD), Postoperative Ileus, Colorectal Surgery
- Trial name
- NCT07271875
- Testing
- Neostigmine + Atropine, Sugammadex
- Volunteers
- 560 people
- Sponsor
- Xijing Hospital
Neuromuscular Blockade, Residual Neuromuscular Blockade
Neuromuscular Blockade Monitoring Using Kine-myography vs Electromyography.
This study aims to compare two monitoring methods of neuromuscular blockade - Kine-myography and Electromyography. The main questions to answer are: are electromyography and kine-myography interchangeable is electromyography…
- Trial name
- NCT05992090
- Where
- Czechia
- Volunteers
- 129 people
- Sponsor
- Masarykova Nemocnice v Usti nad Labem, Krajska Zdravotni a.s.
Inguinal Hernia, Abdominal Wall Muscles
Transversus Abdominis Plane Block and Inguinal Hernia Repair
This prospective, randomized, double blinded, placebo-controlled study is designed to evaluate the postoperative analgesic efficacy of the ultrasound-guided transversus abdominis plane block with ropivacaine 0,75 %, in patients…
- Conditions
- Inguinal Hernia, Abdominal Wall Muscles, Regional Anesthesia, Postoperative Pain
- Trial name
- NCT02030223
- Testing
- Transversus abdominis plane block
- Where
- Greece
- Volunteers
- 59 people
- Sponsor
- Papacharalampous Panagiota
Fibromyalgia
The Effects Of Progressive Muscle Relaxation Training in Women With Fibromyalgia
The purpose of the study is to examine the effects of progressive muscle relaxation training given in addition to a combined exercise program in women with fibromyalgia.
- Trial name
- NCT06243562
- Testing
- combined exercises and progressive muscle relaxation group, combined exercises group
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people
- Sponsor
- Abant Izzet Baysal University
GYN Disorders, Urologic Diseases
Does Depth of Neuromuscular Blockade (NMB) Affect Surgical Conditions in Obese Patients Undergoing Robotic Surgery
A prospective, randomized, outcome trial to evaluate, if depth of neuromuscular blockade (NMB) will affect surgical conditions and postoperative pain based on the degree of neuromuscular block during robotic surgery for…
- Trial name
- NMB (NCT03591289)
- Testing
- NMB with rocuronium bromide
- Where
- United States
- Sponsor
- Rainer Lenhardt