Clinical trials: Neurological Development
Craniosynostoses, Pain, Postoperative
Scalp Block Decreases Pain and Side Effects
Postoperative analgesia after corrective surgery of paediatric craniosynostosis is crucial in term of short and long-term outcomes.
- Trial name
- NCT04133467
- Testing
- scalp block
- Where
- Italy
- Volunteers
- 26 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Sleep Disorder
Melatonin CR for the Treatment of Impaired Sleep Maintenance in 4-8 Year Old Children With Autism Spectrum Disorders
The purpose of this research is to see the effects (good and bad) of Melatonin CR on sleep in 4-8 year old children with autism spectrum disorders and sleep problems.
- Trial name
- NCT01033565
- Testing
- Natrol
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- University of Nebraska
Low Back Pain, Hip Osteoarthritis
Observational Study of the Development of Low Back Pain After Total Hip Arthroplasty.
The investigators are going to observe the appearance of low back pain in patients who have undergone hip prosthesis surgery.
- Conditions
- Low Back Pain, Hip Osteoarthritis, Arthropathy of Hip
- Trial name
- NCT05647629
- Testing
- Total hip arthroplasty
- Where
- 2 sites in Spain
- Volunteers
- 618 people
- Sponsor
- Universidad de Zaragoza
Developmental Articulation Disorder, Speech Disorder
Characteristics of Idiopathic Familial Speech Disorders
According to studies, speech disorders with unknown causes (idiopathic) affect approximately 5% of the population at some point in their life.
- Conditions
- Developmental Articulation Disorder, Speech Disorder, Stuttering
- Trial name
- NCT00001551
- Where
- 2 sites in United States
- Volunteers
- 375 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Developmental Language Disorder and Language Impairment, Specific Language Impairment
Retrieval-Based Word Learning in Developmental Language Disorder During Book Reading II
Children with developmental language disorder (DLD; also referred to as specific language impairment) experience a significant deficit in language ability that is longstanding and harmful to the children's academic, social, and…
- Conditions
- Developmental Language Disorder and Language Impairment, Specific Language Impairment, Language Development
- Trial name
- NCT07048392
- Testing
- Retrieval-based word learning: Repeated Spaced Retrieval condition, Retrieval-based word learning: Repeated Study condition
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Purdue University
Infant Development, Sensory Disorder
The Prechtl's General Movement Assessment, Hammersmith Infant Neurological Examination and Sensory Profile-2
In the Neonatal Intensive Care Unit (NICU), infants encounter many sensory stimuli (excessive noise, bright lights, painful medical applications, etc.) that are not present in the uterus.
- Conditions
- Infant Development, Sensory Disorder, Sensory Processing Disorder, Motor Delay
- Trial name
- highrisk (NCT05217199)
- Testing
- Measurements
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Kahramanmaras Sutcu Imam University
Developmental Delay, Skeletal Abnormalities
Biomarker for Sly Disease (MPS VII) (BioSly)
Development of a new MS-based biomarker for the early and sensitive diagnosis of Sly disease from blood (plasma)
- Conditions
- Developmental Delay, Skeletal Abnormalities, Hepatomegaly, Splenomegaly
- Trial name
- BioSly (NCT02298699)
- Where
- 5 sites in Egypt, Germany and 2 more
- Sponsor
- CENTOGENE GmbH Rostock
Chronic Pain
Feasibility Study of an Online Self-management Program for Chronic Non-cancer Pain
Based on a mixed-methods design, the objective of this trial is to assess the feasibility and acceptability of the "Agir pour moi" program, an 8-week online self-management program for chronic non-cancer pain (CNCP).
- Trial name
- NCT05319652
- Testing
- Pain self-management program
- Where
- Canada
- Volunteers
- 63 people
- Sponsor
- CHU de Quebec-Universite Laval
Autism, Communication Disorders
iPad Application to Treat Prosodic Deficits in Students With Communication Disorders
The purpose of this study is to evaluate the utility of a specialized iPad application designed to treat difficulties with intonation (e.g., melody in voice) in children with autism spectrum disorders (ASD) and other…
- Trial name
- NCT01917864
- Testing
- iPad Application
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Yale University
Delirium, Dementia
Delirium and Cognitive Impairment Development in Hospitalized Older Adults Under Isolation Conditions
The goal of this observational study is to examine if older patients who need to be under isolation precautions due to multidrug resistant bacteria or other reasons have an increased risk of suffering from delirium or cognitive…
- Conditions
- Delirium, Dementia, Cognitive Impairment
- Trial name
- DELiso (NCT07114458)
- Where
- Germany
- Volunteers
- 404 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Global Developmental Delay
Design and Implementation of a Carer Aromatherapy Training (CAT) Program for Children With Global Developmental Delay in Hong Kong: A Mixed Qualitative Study Using the COM-B Framework
This project aims to design and implement a Carer Aromatherapy Training (CAT) program, guided by the Capability, Opportunity, Motivation and Behaviour (COM-B) model, to empower carers with safe and effective aromatherapy…
- Trial name
- CAT programme (NCT07800689)
- Testing
- Carer Aromatherapy Training (CAT) program and home massage with massage oil with the mixture of Petitgrain Mandarin (Citrus reticulate) essential oil and fractionated coconut oil
- Where
- Hong Kong
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Hong Kong Metropolitan University
Scoliosis, Kyphosis
Postoperative and Chronic Pain Genetic Spine and Pectus Surgery Study
This will be an open label, prospective study to determine the association between specific genotypes, epigenetics and behavioral factors, with the phenotypes, defined by pain perception, postoperative pain, analgesic and side…
- Conditions
- Scoliosis, Kyphosis, Kyphoscoliosis, Pectus Excavatum
- Trial name
- NCT02998138
- Where
- 5 sites in United States
- Volunteers
- 880 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Gastric Cancer Stage, Esophageal Cancer
Development and Validation of a Risk Prediction Model for Gastric Retention in Patients Undergoing Sedated Gastroscopy
Gastric retention not only compromises the quality of endoscopic examination but also significantly increases the risk of reflux and aspiration in sedated patients.
- Conditions
- Gastric Cancer Stage, Esophageal Cancer, Gastroparesis
- Trial name
- NCT07104214
- Where
- 3 sites in China
- Volunteers
- 5,000 people
- Sponsor
- Zhejiang University
Fibromyalgia
Development of Treatments Aiming at Improvement of Function in Patients With Chronic Widespread Pain
The study aims to evaluate the effects of adding supervised exercise in supplement to an educational self-management program, and to determine which subgroups would gain effects of the treatment.
- Trial name
- NCT00545649
- Testing
- Exercise and education, Education
- Where
- 3 sites in Sweden
- Volunteers
- 164 people
- Sponsor
- Göteborg University
Retrocochlear Pathology, Auditory Processing Disorder, Central
Cochlear Implantation in Single Sided Deafness and Asymmetrical Hearing Loss: a Cost/Utility Study.
The investigators assume that cochlear implants in this indication are not only effective but also cost-effective. The investigators' experimental protocol relies on real life therapeutic strategy, where a cochlear implant may be…
- Conditions
- Retrocochlear Pathology, Auditory Processing Disorder, Central, Major Cochlear Ossification or Malformation
- Trial name
- CISSD (NCT02204618)
- Testing
- cochlear implantation, 6 months initial abstention
- Where
- France
- Volunteers
- 160 people
- Sponsor
- University Hospital, Toulouse
Cognitive Disorder, Metabolic Disease
Characterization of Dysmorphology in Subjects With Creatine Transporter Deficiency
Background: Creatine transporter deficiency (CTD) is a genetic disorder that mainly affects the brain in males. CTD causes intellectual disability that can be mild to severe.
- Conditions
- Cognitive Disorder, Metabolic Disease, Autism Spectrum Disorder
- Trial name
- NCT05600946
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Hearing Loss, Speech and Language Development Delay Due to Hearing Loss
Teletherapy in Children Who Are Deaf and Hard of Hearing
This study seeks to determine the effectiveness of speech/language teletherapy to address disparities in speech and language outcomes in children who are deaf or hard-of-hearing (D/HH).
- Trial name
- NCT04928209
- Testing
- Speech-Language Teletherapy
- Where
- 5 sites in United States
- Volunteers
- 210 people
- Sponsor
- University of California, San Francisco
Hearing Loss
Maximizing Language Development in Children With Hearing Loss
The purpose of this study is to evaluate the effects of early intervention on language skills for children with hearing loss.
- Trial name
- NCT01963468
- Testing
- Early language intervention
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Pain, Development
Trial of Repeated Analgesia With Kangaroo Care
Mothers can provide pain relief to their newborns, even in the context of intensive neonatal care. There is a recent accumulation of data, being analyzed by ourselves in a Cochrane review, that mothers holding their infants in a…
- Trial name
- TRAKC (NCT01561547)
- Testing
- Kangaroo Mother Care, Sucrose
- Where
- Canada
- Volunteers
- 242 people
- Sponsor
- IWK Health Centre
Developmental Delay
Bright by Three (BB3) Effectiveness Study
The Investigators propose to conduct a pragmatic randomized controlled trial of 350 one to four year old children and their caregivers to study the effectiveness of 1) the Bright By Three (BB3) intervention for promoting…
- Trial name
- NCT02717390
- Testing
- Bright By Three (BB3), Texts for Child Safety (TCS)
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
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