Clinical trials: Neurologic Ambulation Disorder
Stroke
Influence of Assistive Device Use While Performing Dual Task in Patients With Stroke
The primary purposes of the this three-year research proposal are to investigate the influence of assistive device use on dynamic balance and the associated attentional demands during standing and walking in patients with stroke
- Trial name
- NCT00173719
- Testing
- Standard cane
- Where
- Taiwan
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Multiple Sclerosis
VR and Orthoses for Rehabilitation in Multiple Sclerosis
This non-drug, non-medical device, interventional study explores the feasibility of integrating virtual reality (VR) with wearable sensors to support gait training using a passive orthosis in individuals with multiple sclerosis…
- Trial name
- VIRTUE (NCT07096700)
- Testing
- VR and walking brace-based gait rehabilitation
- Where
- 2 sites in Italy
- Volunteers
- 12 people
- Sponsor
- Azienda Usl di Bologna
Parkinson Disease, Walking, Difficulty
BeatPark: Self-rehabilitation in Walking With Parkinson's Disease
Physical activity has beneficial effects on the quality of walking for persons with Parkinson's disease (PD). However, regular physical activity is still limited in most patients' daily lives.
- Trial name
- BeatPark (NCT04543058)
- Testing
- BeatPark Application, BeatPark Application without synchronized music, BeatPark Application without music
- Where
- France
- Volunteers
- 396 people
- Sponsor
- Clinique Beau Soleil
Multiple Sclerosis
Unraveling Early Walking Dysfunction in Non-disabled MS People: Assessment and Potential Therapeutic Interventions
The aim of the study is to set up a pilot study to investigate the effects of treadmill training in preventing the onset and worsening of walking impairments, balance deficits and fatigue.
- Trial name
- NCT03492450
- Testing
- Treadmill training
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- Fondazione Don Carlo Gnocchi ETS
Stroke, Gait, Hemiplegic
A Comparison Between the Exoskeleton Hybrid Assistive Limb and Conventional Gait Training Early After Stroke
Overall aim is to evaluate HAL for gait training early after stroke and the effect of HAL on short- and long-term functioning, disability and health compared to conventional gait training as part of an inpatient rehabilitation…
- Conditions
- Stroke, Gait, Hemiplegic, Ambulation Difficulty, Hemiparesis
- Trial name
- HAL-RCT (NCT02410915)
- Testing
- Hybrid Assistive Limb (HAL); gait training, Control Group; Conventional gait training
- Where
- Sweden
- Volunteers
- 32 people
- Sponsor
- Danderyd Hospital
Stroke, Acute, Stroke, Ischemic
Effects of Atalante Exoskeleton on Gait Recovery in Non- or Poorly Ambulatory Patients With Hemiparesis in the Acute/Subacute Phase (Month 1 to 4)
The present clinical investigation - EarlyExo, is an interventional, international, multicentric, prospective, single-blinded randomized controlled trial.
- Conditions
- Stroke, Acute, Stroke, Ischemic, Stroke, Subacute, Stroke Hemorrhagic
- Trial name
- EarlyExo (NCT06107010)
- Testing
- Use of the Atalante exoskeleton
- Where
- 5 sites in France, Germany and 1 more
- Volunteers
- 66 people
- Sponsor
- Wandercraft
Multiple Sclerosis
Safety and Efficacy Study of Oral Fampridine-SR in Patients With Multiple Sclerosis
Multiple Sclerosis (MS) is a disorder of the body's immune system that affects the Central Nervous System (CNS). Normally, nerve fibers carry electrical impulses through the spinal cord, providing communication between the brain…
- Trial name
- NCT00053417
- Testing
- 10 milligram (mg) fampridine-SR (4-aminopyridine, 4-AP), 15 mg fampridine-SR (4-aminopyridine, 4-AP), 20 mg fampridine-SR (4-aminopyridine, 4-AP)
- Where
- 25 sites in United States, Canada
- Volunteers
- 206 people
- Sponsor
- Acorda Therapeutics
Injuries, Spinal Cord
Dual-task Obstacle Crossing Training in Ambulatory Subjects With Spinal Cord Injury
Is dual-task obstacle crossing training more efficiently than single-task obstacle crossing training on the improvement of walking ability, balance ability, and lower extremity muscle strength in ambulatory subjects with spinal…
- Trial name
- NCT02917590
- Testing
- Dual-task obstacle crossing training, Single-task obstacle crossing training
- Volunteers
- 7 people
- Sponsor
- Khon Kaen University
Stroke, Hemiparesis
Locomotor Training for Neurological Disease
The purpose of this study is to determine whether split belt training can be used to treat walking pattern deficits from stroke and to determine whether different schedules and types of long term training on a custom split belt…
- Trial name
- NCT01288040
- Testing
- Split Belt treadmill
- Where
- United States
- Volunteers
- 92 people
- Sponsor
- Hugo W. Moser Research Institute at Kennedy Krieger, Inc.
Spinal Cord Injury, Chronic Neuropathic Pain
VIRTUAL WALKING AND TRANSCRANIAL DIRECT CURRENT STIMULATION FOR CHRONIC NEUROPATHIC PAIN DUE TO SPINAL CORD INJURY
The goal of this feasibility study is to assess the feasibility of the combined treatment intervention "virtual walking (VW) and transcranial direct current stimulation (tDCS)" of neuropathic pain in patients with spinal cord…
- Trial name
- NCT06710808
- Testing
- Virtual walking and transcranial direct current stimulation
- Where
- Switzerland
- Volunteers
- 4 people
- Sponsor
- Swiss Paraplegic Research, Nottwil
Stroke, Cerebral Vascular Disorders
Discrete Versus Rhythmic Gait Training
The objective of this study is to compare the effects of novel versus standard locomotor training using a robotic gait orthosis (LT-RGO) after stroke.
- Trial name
- NCT02650440
- Testing
- Novel Protocol, Standard Protocol
- Where
- Brazil
- Volunteers
- 20 people
- Sponsor
- Thais Amanda Rodrigues
Rehabilitation
Changes in Physical Activity in All Day Life in People With MS Before and After Rehabilitation
The primary objective is to observe the impact of in-patient rehabilitation on physical activity in daily life using miniature, wearable sensors, fixed on the shoes. These sensors record data about various aspects of walking.
- Trial name
- NCT03769636
- Testing
- GaitUp Physilog 5
- Where
- Switzerland
- Volunteers
- 30 people
- Sponsor
- Klinik Valens
Stroke, Hemiplegia
Task-Oriented Training Versus High-Intensity Gait Training in People With Chronic Stroke
The purpose of this study is to compare the effects of high-repetition task-oriented training and high-intensity gait training on walking capacity and functional mobility in individuals with chronic stroke.
- Conditions
- Stroke, Hemiplegia, Chronic Stroke
- Trial name
- NCT07725211
- Testing
- Neurodevelopmental Treatment, High-Repetition Task-Oriented Training, High-Intensity Gait Training
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people
- Sponsor
- Istanbul University - Cerrahpasa
Spinal Cord Injuries, Neuropathic Pain
Brain Activity Patterns in Persons With Spinal Cord Injury and Neuropathic Pain After a Virtual Walking Training Program
The aim of this pilot study is to explore the association of changes in pain perception with changes in brain activity (functional Magnetic Resonance Imaging (fMRI)) and metabolic (Magnetic Resonance Spectroscopy (MRS)) patterns…
- Trial name
- VRandMRI (NCT05098587)
- Where
- Switzerland
- Volunteers
- 12 people
- Sponsor
- Swiss Paraplegic Research, Nottwil
Parkinson's Disease
Ambulosono Rasagiline Musical Walking Study
This study will investigate the effects of a contingency-based musical walking intervention program called Ambulosono on neural mechanisms in the brain.
- Trial name
- NCT02207387
- Testing
- Azilect, Exercise, Music
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- University of British Columbia
Sensorimotor Gait Disorder, Neurologic Ambulation Disorder
Clinical Study of the L300 Versus Ankle-foot Orthosis (AFO) on Post-Stroke Subjects With Foot Drop
The objective of this study is to determine the effectiveness of the NESS L300 (L300) in improving gait parameters, function, and quality of life among stroke subjects (greater than or equal to 3 months post stroke)with drop foot.
- Conditions
- Sensorimotor Gait Disorder, Neurologic Ambulation Disorder, Gait, Drop Foot, Poststroke Hemiparesis
- Trial name
- L300 (NCT01138995)
- Testing
- Ness L300, Ankle-foot orthosis
- Where
- 11 sites in United States
- Volunteers
- 197 people
- Sponsor
- Bioness Inc
Morbid Obesity, Postoperative Pain
Patients-Controlled Epidural Analgesia After Gastric Bypass for Morbid Obesity Using Morphine-Levobupivacaine Regimens
Adequate postoperative analgesia can facilitate recovery following gastric bypass surgery for morbid obesity. The efficacy and safety of intravenous patient - controlled analgesia has been studied, but up to date no data are…
- Conditions
- Morbid Obesity, Postoperative Pain, Postoperative Bowel Function, Postoperative Ambulation
- Trial name
- NCT01249872
- Testing
- GROUP A : 0 mg MORPHINE-0.1% LEVOBUPIVACAINE, GROUP B : 1 mg MORPHINE- 0.1% LEVOBUPIVACAINE, GROUP C : 2 mg MORPHINE-0.1% LEVOBUPIVACAINE
- Where
- Greece
- Volunteers
- 96 people
- Sponsor
- University of Patras
Acute Stroke, Stroke, Ischemic
Measuring Ambulation, Motor, and Behavioral Outcomes With Post-Stroke Fluoxetine in Tanzania
This is a phase II, randomized study of 120 adults age 18 or above who will prescribed 20mg daily Fluoxetine for 90 days following acute, ischemic stroke.
- Trial name
- MAMBO (NCT03728153)
- Testing
- Fluoxetine 20 MG Oral Tablet
- Where
- Tanzania
- Volunteers
- 34 people
- Sponsor
- Massachusetts General Hospital
Multiple Sclerosis
Endurance and Walking Training by Nordic Walking in Multiple Sclerosis
Walking capacity is one of the most valuable body functions among persons with multiple sclerosis (MS) and it is one of the most frequently affected, even in early stages of the disease.
- Trial name
- NCT03976128
- Testing
- Nordic Walking Training, Conventional endurance training
- Where
- Spain
- Volunteers
- 66 people
- Sponsor
- Multiple Sclerosis Center of Catalonia
Cerebral Palsy
Effect of Dysport Injections on Energy Expenditure and Walking Efficiency in Children With Cerebral Palsy
This study aims to evaluate the efficacy of single event multi level chemoneurolysis with the abobotulinumtoxin A drug, Dysport®, on walking energy expenditure and gait in children with spastic diplegia cerebral palsy.
- Trial name
- NCT03469999
- Testing
- Dysport Injectable Product
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Columbia University
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