Clinical trials: Neurogenic Bladder Dysfunction
Neurogenic Urinary Bladder Disorder, Urinary Bladder, Neurogenic
Efficacy and Tolerability of Propiverine Hydrochloride in Patients With Neurogenic Detrusor Overactivity
The purpose of this clinical study is to compare efficacy and safety of propiverine hydrochloride extended and immediate release formulations in patients suffering from neurogenic detrusor overactivity.
- Conditions
- Neurogenic Urinary Bladder Disorder, Urinary Bladder, Neurogenic, Bladder Disorder, Neurogenic, Urinary Bladder Disorder, Neurogenic
- Trial name
- NCT01530620
- Testing
- Propiverine hydrochloride ER (extended release), Propiverine hydrochloride IR (immediate release)
- Where
- 3 sites in Austria, Germany and 1 more
- Volunteers
- 66 people
- Sponsor
- APOGEPHA Arzneimittel GmbH
Lower Urinary Tract Symptoms
Group Versus Individual Urotherapy for Children
What are we doing? A pilot research study is planned to take place within the Pediatric Urology program at McMaster Children's hospital starting this spring/summer 2012.
- Trial name
- NCT01570673
- Testing
- Group urotherapy, Individual Urotherapy
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- Hamilton Health Sciences Corporation
Vesico-ureteral Reflux, Spinal Cord Injury
Reflux in Spinal Cord Injury Patients With Neurogenic Lower Urinary Tract Dysfunction
The purpose of this study is to investigate the incidence of reflux in patients with spinal cord injury in relation to the lesion level, duration of injury and bladder management
- Trial name
- NCT01297673
- Testing
- video-urodynamic examination
- Where
- Switzerland
- Volunteers
- 120 people
- Sponsor
- Balgrist University Hospital
Neurogenic Bladder Dysfunction
Bladder and TranscUtaneous Tibial Nerve Stimulation for nEurogenic Lower Urinary Tract Dysfunction
Many patients with neurological diseases suffer from neurogenic lower urinary tract dysfunction (NLUTD), which often severely impairs quality of life, due to urinary urgency with or without incontinence and voiding dysfunction.
- Trial name
- bTUNED (NCT04315142)
- Testing
- Experimental TTNS
- Where
- 12 sites in Belgium, Brazil and 2 more
- Volunteers
- 48 people
- Sponsor
- University of Zurich
Neurogenic Bladder, Bladder Dysfunction
Vascularized Composite Bladder Allograft Transplantation
This phase 0 trial tests the feasibility, functionality, and sustainability of vascularized composite bladder allograft transplantation in treating patients with terminal bladder pathology.
- Conditions
- Neurogenic Bladder, Bladder Dysfunction, Immunosuppression
- Trial name
- NCT05462561
- Testing
- Quality-of-Life Assessment, Robotic Vascularized Composite Bladder Allograft Transplantation
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- University of Southern California
Neurogenic Bladder Dysfunction
Chronic Electrical Stimulation to Reduce Bladder Hyperreflexia
Bladder spasms after spinal cord injury (SCI) can result in incontinence, urinary tract infections, kidney damage, trigger dangerous increases in blood pressure and decrease independence and quality of life.
- Trial name
- NCT03472599
- Testing
- Genital Nerve Stimulation
- Where
- 2 sites in United States
- Volunteers
- 17 people
- Sponsor
- VA Office of Research and Development
Myelomeningocele, Neurogenic Bladder
Efficacy of Contrast Enhanced Voiding Urosonography for Urodynamic Studies
The investigators will assess the feasibility of replacing fluoroscopy/iodinated contrast with ultrasound/sulfur hexafluoride lipid-type A microspheres during routine urodynamic studies.
- Conditions
- Myelomeningocele, Neurogenic Bladder, Tethered Cord Syndrome, Bladder, Neurogenic
- Trial name
- NCT04738539
- Testing
- Contrast Enhanced Voiding Urosonography with Urodynamic Testing, Urodynamic Testing
- Where
- United States
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Chronic Kidney Diseases, Bladder Dysfunction
Concomitant Renal and Urinary Bladder Allograft Transplantation
The purpose of this study is to establish if concomitant renal and vascularized urinary bladder allograft transplantation is feasible.
- Conditions
- Chronic Kidney Diseases, Bladder Dysfunction, Bladder Absence, Posterior Urethral Valve
- Trial name
- NCT04626167
- Testing
- Concomitant Renal and Urinary Bladder Allograft Transplantation
- Where
- 2 sites in United States
- Volunteers
- 30 people
- Sponsor
- Mayo Clinic
Neurogenic Bladder
Effect of Tamsulosin vs Prazosin in Treatment of Female Voiding Dysfunction
The purpose of this study is to determine whether Tamsolusin or Prazosin are effective in the treatment of female voiding dysfunction(BOO)
- Trial name
- NCT00602186
- Testing
- tamsolusin, prazosin
- Volunteers
- 80 people
- Sponsor
- Tabriz University
Spinal Cord Injuries, Neurogenic Lower Urinary Tract Dysfunction
Patient and Caregiver Perspectives on Intravesical Instillations for Urinary Symptoms
The goal of this observational qualitative study is to learn about the experiences and perspectives of patients with neurogenic lower urinary tract dysfunction (NLUTD) and their caregivers regarding different types of…
- Conditions
- Spinal Cord Injuries, Neurogenic Lower Urinary Tract Dysfunction, Neurogenic Bladder
- Trial name
- NCT07390591
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Medstar Health Research Institute
Neurogenic Bladder Dysfunction
Transcutaneous Tibial Nerve Stimulation for Treating Neurogenic Lower Urinary Tract Dysfunction
Many patients with neurological diseases suffer from neurogenic lower urinary tract dysfunction (NLUTD), which often severely impairs quality of life, due to urinary urgency with or without incontinence and voiding dysfunction.
- Trial name
- NCT02859844
- Testing
- Transcutaneous Tibial Nerve Stimulation (TTNS)
- Where
- 2 sites in Switzerland
- Volunteers
- 9 people
- Sponsor
- University of Zurich
Urinary Bladder Neurogenic Dysfunction
Neuro-urological Outcome After Spinal Cord Injury
Most patients with spinal cord injury suffer from bladder dysfunction which may - especially in the long-term - impair renal function. Improved treatment during the last decades improved life expectancy and quality of life.
- Trial name
- NCT01297660
- Testing
- Video-urodynamic examination
- Where
- Switzerland
- Volunteers
- 55 people
- Sponsor
- Balgrist University Hospital
Incontinence, Urinary, Bladder Dysfunction
Bladder Neck Surgery in Children With Neurogenic Bladder
Surgical outcomes of bladder neck surgery in children with neurogenic bladder. Consequences on bladder voiding.
- Conditions
- Incontinence, Urinary, Bladder Dysfunction, Spina Bifida, Neurogenic Bladder
- Trial name
- CERPED (NCT05861011)
- Where
- France
- Volunteers
- 48 people
- Sponsor
- University of Lorraine
Spinal Cord Injury, Neurogenic Lower Urinary Tract Dysfunction
Correlation of Ultrasound-Measured Detrusor and Bladder Wall Thickness With Urodynamic Parameters in Spinal Cord Injury
This study aims to investigate the correlation between detrusor and bladder wall thickness measured by suprapubic ultrasound and urodynamic parameters in patients with spinal cord injury.
- Trial name
- NCT07419165
- Where
- Turkey (Türkiye)
- Volunteers
- 116 people
- Sponsor
- Ankara City Hospital Bilkent
Spinal Cord Injuries, Neurogenic Bowel
Prebiotics for Spinal Cord Injury Patients With Bowel and Bladder Dysfunction
An investigator initiated pilot study: two arm, double blind, placebo controlled, randomized, group of approximately 60 patients with spinal cord injury, and who have evidence of neurogenic bladder.
- Conditions
- Spinal Cord Injuries, Neurogenic Bowel, Bladder Dysfunction
- Trial name
- NCT03987126
- Testing
- Human Milk Oligosaccharides (HMO)
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Bladder Dysfunction, Neurogenic Bladder Dysfunction
Feasibility Study of Transcutaneous Tibial Nerve Stimulation for Urinary Symptoms in People With Multiple Sclerosis
Neurogenic lower urinary tract dysfunction is common among people with Multiple sclerosis with a pooled prevalence of 68.41% using self-report measures and 63.95% using urodynamic studies.
- Conditions
- Bladder Dysfunction, Neurogenic Bladder Dysfunction, Urinary Incontinence, Urinary Bladder, Overactive
- Trial name
- NCT04528784
- Testing
- Transcutaneous tibial nerve stimulation
- Where
- Ireland
- Volunteers
- 23 people
- Sponsor
- University of Limerick
Neurogenic Bladder Dysfunction
Health-related Quality of Life of Patients With Neurogenic Bladder
Bladder management has a major impact on the quality of life in patients with neurogenic bladder dysfunction. This a prospective investigation of the effects of the method for bladder evacuation on the health-related quality of…
- Trial name
- NCT02179073
- Where
- Switzerland
- Volunteers
- 87 people
- Sponsor
- Swiss Paraplegic Research, Nottwil
Neurogenic Bladder Disorder, Non-Neurogenic Bladder
Define Final Selection Choice Criteria for a Coloplast Catheter Ensuring Highest Patient Satisfaction Via Surveys (EVA).
Understanding the Coloplast Intermittent Catheter Selection Study: This study aims to understand how adults who need to use catheters to empty their bladder by themselves decide which Coloplast catheter works best for them.
- Conditions
- Neurogenic Bladder Disorder, Non-Neurogenic Bladder, Bladder Dysfunction, Urinary Retention
- Trial name
- EVA (NCT07355803)
- Testing
- Questionnaires : Patient questionnaire on catheter use and satisfaction, IC-Di-Q, and I-CAT
- Where
- Belgium
- Volunteers
- 22 people
- Sponsor
- Coloplast NV/SA
Spinal Vascular Disorder Nos, Neurogenic Bladder Dysfunction Nos
Measurement of Bladder Function Change In Patients With SVMs Before and After Surgical Intervention
The investigators goal is to create a better understanding of patient with SVMs reported outcomes for bladder management strategies before and after surgery.
- Trial name
- NCT03280186
- Testing
- surgery
- Volunteers
- 100 people
- Sponsor
- Xuanwu Hospital, Beijing
Overactive Detrusor, Detrusor Hyperreflexia of Bladder
Onabotulinumtoxina Intradetrusorial Injections and NGF Expression
In the last years, botulinum toxin type A (onab/A) has been increasingly used as a treatment option for overactive bladder symptoms in patients affected by either neurogenic and idiopathic detrusor overactivity (DO).
- Trial name
- Onab/A-NGF (NCT01629433)
- Where
- Italy
- Volunteers
- 25 people
- Sponsor
- University Of Perugia