Clinical trials: Neurodevelopmental Delay
Developmental Delay, Child Development
Prevalence of Developmental Delays in Preschool Children and the Role of Early Physical Therapy
This study was done to determine the prevalence of developmental delays among preschool children in Damietta and to evaluate the effect of early physical therapy intervention on children diagnosed with developmental delays.
- Conditions
- Developmental Delay, Child Development, Physical Therapy
- Trial name
- NCT07555028
- Testing
- domain-specific physical therapy interventions
- Where
- Egypt
- Volunteers
- 300 people
- Sponsor
- Horus University
Williams Syndrome, Child
Clemastine Fumarate in the Treatment of Neurodevelopmental Delays in Williams Syndrome
This study focuses on therapeutic targets for cognitive, motor, and social impairments in Williams syndrome by reversing brain myelin defects caused by GTF2I.
- Conditions
- Williams Syndrome, Child, Neurodevelopmental Delay
- Trial name
- NCT06315699
- Testing
- Clemastine Fumarate Tablets, corn starch tablets
- Where
- China
- Volunteers
- 28 people
- Sponsor
- Qilu Hospital of Shandong University
Developmental Delay
Development and Effectiveness of Home-based Programs for Preschool Children With Developmental Delay
Early intervention refers to the provision of early detection, early diagnosis, and early intervention for infants and young children with special needs.
- Trial name
- NCT02115334
- Testing
- professional therapists delivering the PHPA, parents executing the PHPA, health education
- Where
- Taiwan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Neurodevelopmental Delay
General Anesthesia/Surgical Exposure on White Matter Development in Children
International large-scale clinical studies have found that prolonged or repeated exposure to general anesthesia drugs in infancy and early childhood can lead to an increased risk of long-term neurodevelopmental abnormalities in…
- Trial name
- NCT06367062
- Testing
- MRI
- Volunteers
- 210 people
- Sponsor
- Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University
Autism Spectrum Disorder, Developmental Delay
A Salivary miRNA Diagnostic Test for Autism
The goal of this study is to validate a panel of miRNAs that distinguish children with autism spectrum disorder (ASD) from their non-ASD peers with a positive MCHAT-R.
- Trial name
- NCT02832557
- Testing
- Salivary collection, Vineland Adaptive Behavior Scale-III Assessment, Medical history questionaire
- Where
- United States
- Volunteers
- 998 people, healthy volunteers welcome
- Sponsor
- State University of New York - Upstate Medical University
Behavior, Child
Teacher Child Interaction Training (TCIT): Randomized Control Trial
This study is being conducted to evaluate the effects of TCIT on child development, child behavior, and teacher use of skills in the classroom.
- Trial name
- NCT04000230
- Testing
- TCIT, Booster
- Where
- 4 sites in United States
- Volunteers
- 622 people, healthy volunteers welcome
- Sponsor
- University of Miami
Intellectual Disabilities, Speech Delay
Pivotal Response Treatment for Individuals With Intellectual Disabilities
The investigators will assess the efficacy of Pivotal Response Treatment (PRT) in the treatment of communication deficits in children with intellectual disabilities.
- Conditions
- Intellectual Disabilities, Speech Delay, Language Disorder
- Trial name
- NCT01988623
- Testing
- Pivotal Response Treatment (PRT)
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- Stanford University
Developmental Delay
Effects of Power Ball on Proximal Muscle and Refractive Errors in Developmental Delay.
When a child does not meet developmental milestones at the anticipated times, it is referred to as having a developmental delay. These benchmarks cover social, emotional, cognitive, physical, and communication abilities.
- Trial name
- NCT06461572
- Testing
- conventional therapy, conventional therapy along with standard therapy and stability exercises.
- Where
- Pakistan
- Volunteers
- 32 people
- Sponsor
- Riphah International University
Attention Deficit Hyperactivity Disorder, Problem Behavior
Stimulant Effects on Disruptive Behavior
The goal of this study is to determine the effects of stimulant medication on disruptive behavior, function, preference and choice; however, it is primarily methodological and will add to current research by establishing an…
- Trial name
- NCT03420339
- Testing
- Stimulant
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Matthew J O'Brien, PhD, BCBA-D
Dementia, Cognitive Decline
Ammonia Levels and Cognitive Impairment
The purpose and objective of this study is to determine the prevalence of elevated ammonia levels in subjects with cognitive impairment, and to observe if treating the cause of the elevated ammonia level improves mental status.
- Conditions
- Dementia, Cognitive Decline, Cognitive Impairment, Developmental Delay
- Trial name
- NCT02059356
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Duke University
Obesity, Blood Pressure
Upstate New York Infant Development Screening Program
The goal of the Upstate KIDS Study is to track the growth, development and long-term health of children given the increasing use of infertility treatment, occurrence of maternal obesity and pregnancy complications, and rising…
- Conditions
- Obesity, Blood Pressure, Motor Delay, Developmental Delay
- Trial name
- Upstate KIDS (NCT03106493)
- Testing
- None (observational)
- Volunteers
- 6,171 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Autism, Development Delay
Use of Virtual Reality Game Playing During Venipuncture
To evaluate the impact of using virtual reality, VR, game playing on successful completion and reduction of distress and pain in pediatric venipuncture, and to increase adherence in obtaining the desired blood volume.
- Conditions
- Autism, Development Delay, Typical Development
- Trial name
- NCT03518346
- Testing
- Virtual Reality, Standard of Care
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- University of California, Davis
Problem Behavior, Developmental Delay
Problem Behavior Assessment and Intervention in IDEA Part C Services
The purpose of this study is to evaluate the effect of function-based assessment and intervention to reduce problem behavior in children with developmental disability or delay in the context of IDEA Part C services.
- Conditions
- Problem Behavior, Developmental Delay, Developmental Disability
- Trial name
- NCT06771284
- Testing
- Function-based assessment and intervention
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- University of Nevada, Las Vegas
Klinefelter Syndrome, Trisomy X
The eXtroardinarY Babies Study: Natural History of Health and Neurodevelopment in Infants and Young Children With Sex Chromosome Trisomy
This study is designed to research the natural history of neurodevelopment, health and early hormonal function in infants with XXY/Klinefelter syndrome, XYY, XXX and other sex chromosome variations in an effort to identify early…
- Conditions
- Klinefelter Syndrome, Trisomy X, XYY Syndrome, XXXY and XXXXY Syndrome
- Trial name
- NCT03396562
- Testing
- Assessments of Development and Growth
- Where
- 2 sites in United States
- Volunteers
- 300 people
- Sponsor
- University of Colorado, Denver
Global Developmental Delay
Virtual Reality and Neuropsychiatric Rehabilitation in Patients With Global Developmental Delay.
Global Developmental Delay is a disorder characterized by failure achievement of expected milestones in different areas of psychomotor development before 5 years of age.
- Trial name
- NCT05879952
- Testing
- TAU + BTsN session, TAU
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- IRCCS Centro Neurolesi Bonino Pulejo
Behavior Problem, Development Delay
Family Nurture Intervention, A Group Model in Connecticut
The purpose of this current study is to investigate the efficacy of a group model of Family Nurture Intervention in ameliorating behavioral problems in preschool-aged children.
- Conditions
- Behavior Problem, Development Delay, Emotional Disturbance, Family Conflict
- Trial name
- NCT02970565
- Testing
- Family Nurture Intervention, Nutrition and Play Intervention
- Where
- United States
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- Columbia University
Developmental Delay
Occupational Therapy in the Context of Head Start
The purpose of this study is to identify the role of occupational therapy within Head Start programs. Representatives within Head Start will be asked to participate in a nationwide internet based survey identifying the amount and…
- Trial name
- NCT01975506
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- Texas Woman's University
Developmental Delay, Behavioural Problem
Early Detection and Intervention in Developmental Delay / Behavioral Problems in Preschool Children - PLUSS
The PLUSS (Mental health, learning, development, collaboration around preschool children) is a collaborative project involving guardians, Jönköping County´s health care, preschools and social services.
- Conditions
- Developmental Delay, Behavioural Problem, Neurodevelopmental Delay
- Trial name
- PLUSS (NCT04815889)
- Testing
- PRIMUS parent training Group
- Where
- Sweden
- Volunteers
- 600 people
- Sponsor
- Region Jönköping County
Developmental Delay, Iron Deficiency
Early Versus Delayed Cord Clamping at Term: Neurodevelopmental Outcomes in Swedish Infants at 4 Years of Age
Delayed clamping of the umbilical cord might prevent or slow the onset of iron deficiency by increasing the infant's iron endowment at birth.
- Trial name
- NCT01581489
- Testing
- Time to clamping of the umbilical cord after delivery
- Where
- Sweden
- Volunteers
- 263 people
- Sponsor
- Uppsala University
Intellectual Disabilities Global Developmental Delay
Dyadic Creative Arts Therapies-based Intervention for Children With Intellectual and Developmental Disabilities
Background: Interactions between parents and children with intellectual and developmental disabilities (IDD) tend to be directive and didactic lacking in playfulness and enjoyment.
- Trial name
- NCT06541782
- Testing
- Dyadic CAT-based Intervention, Psycho-Educational Parent Counseling
- Where
- Israel
- Volunteers
- 60 people
- Sponsor
- University of Haifa