Clinical trials: Nerve Pain
Plantar Fasciitis, Heel Pain
Baxter's Nerve Pulsed Radiofrequency Versus Platelet-Rich Plasma Injection or Both Together as a Treatment Modality of Recalcitrant Plantar Fasciitis
Plantar fasciitis is a common condition causing chronic heel pain due to degenerative changes in the tissue supporting the arch of the foot.
- Conditions
- Plantar Fasciitis, Heel Pain, Nerve Compression Syndromes
- Trial name
- NCT07826234
- Testing
- Baxter's Nerve Pulsed Radiofrequency, Autologous Platelet-Rich Plasma Injection
- Volunteers
- 75 people
- Sponsor
- Assiut University
Hip Fracture, Pain Management
Comparison of the Efficacy of Ultrasound-guided Supra-inguinal Fascia Iliaca and Lumbar Erector Spina Plan Block in Hip Fractures
The aim of our study was to evaluate the efficacy and patient satisfaction level of SI-FIB and lumbar ESPB for positioning and postoperative analgesia during spinal anesthesia in patients undergoing hip fracture surgery.
- Conditions
- Hip Fracture, Pain Management, Multimodal Analgesia, Peripheral Nerve Block
- Trial name
- NCT07639762
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Sehit Prof. Dr. Ilhan Varank Sancaktepe Training and Research Hospital
Paresthesia, Total Hip Arthroplasty (THA)
Percussive vs. Gentle Massage for Recovery After Hip Replacement
Many people who have hip replacement surgery through a "bikini incision" on the front of the hip (anterior approach) develop numbness, tingling, burning, or tightness in the front and side of the thigh afterward.
- Conditions
- Paresthesia, Total Hip Arthroplasty (THA), Direct Anterior Total Hip Arthroplasty, Lateral Femoral Cutaneous Nerve Injury
- Trial name
- NCT07790705
- Testing
- Percussive Massage Therapy (Toloco or Hyperice Hypervolt GO 2), Gentle Manual Massage
- Where
- United States
- Volunteers
- 58 people
- Sponsor
- Zachary M Ricciardelli
Intercostal Nerve Block, Serratus Posterior Superior Intercostal Plane Block
Analgesic Efficiency of SIPSPB vs ICNB in VATS Surgery
This study aims to evaluate the effectiveness of Serratus Posterior Superior Intercostal Plane (SPSIP) block compared to Intercostal Nerve (ICN) block in terms of postoperative pain control, reduction of opioid analgesic…
- Conditions
- Intercostal Nerve Block, Serratus Posterior Superior Intercostal Plane Block, Post-operative Pain Management, VATS
- Trial name
- NCT07577908
- Where
- Turkey (Türkiye)
- Volunteers
- 82 people
- Sponsor
- Kocaeli City Hospital
Postoperative Pain Breast Reduction, Mammaplasty
SPSIP Block for Pain Control After Breast Reduction Surgery
The goal of this clinical trial is to learn whether an ultrasound-guided serratus posterior superior intercostal plane block (SPSIP block) can lower the need for opioid pain medicine after breast reduction surgery.
- Conditions
- Postoperative Pain Breast Reduction, Mammaplasty, Analgesia, Nerve Block
- Trial name
- SPSIP-RM (NCT07657949)
- Testing
- Ultrasound-Guided Serratus Posterior Superior Intercostal Plane Block, Standard Perioperative Pain Treatment
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Cumhuriyet University Hospital
Functional Endoscopic Sinus Surgery, Vagal Nerve Stimulation
Auricular Neuromodulation for FESS
In this blinded prospective randomized control trial the researchers will investigate the impact of cutaneous vagal nerve stimulation on surgical conditions in patients undergoing functional and ascorbic sinus surgery (FESS).
- Conditions
- Functional Endoscopic Sinus Surgery, Vagal Nerve Stimulation, Platelet Activation
- Trial name
- NCT06662422
- Testing
- Spark Biomedical Sparrow Ascent Transcutaneous Auricular Neurostimulation (tAN) System
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Total Shoulder Arthroplasty, Reverse Total Shoulder Arthroplasty
Continuous Interscalene Blocks and Rebound Pain
The primary objectives of this present study are to examine whether a continuous interscalene block of a total duration of 48 hours reduces the incidence of rebound pain comparatively to single-shot interscalene block, through…
- Conditions
- Total Shoulder Arthroplasty, Reverse Total Shoulder Arthroplasty, Interscalene Analgesia, Interscalene Blocks
- Trial name
- NCT07770165
- Testing
- Continuous interscalene nerve block, Interscalene Block
- Where
- Canada
- Volunteers
- 154 people
- Sponsor
- University of Calgary
Peripheral Nerve Stimulation, Genicular Nerves
Peripheral Nerve Stimulation of Genicular Nerves Versus Conventional Therapy With Intra-articular Steroid Injection for Chronic Knee Pain: A Prospective, Randomized Pilot Study
To compare the effects of the following types of therapy on knee range of motion when given to patients with chronic knee pain: A standard steroid injection Peripheral nerve stimulation (PNS) therapy in combination with a…
- Conditions
- Peripheral Nerve Stimulation, Genicular Nerves, Chronic Knee Pain
- Trial name
- NCT06004882
- Testing
- PNS therapy, Triamcinolone, Bupivacaine
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- M.D. Anderson Cancer Center
Arthroplasty, Replacement, Knee, Nerve Block Assessment
Ultrasonographic Predictors of Adductor Canal Block Effectiveness in Total Knee Arthroplasty
Total knee arthroplasty (TKA) is associated with substantial postoperative pain and opioid requirements, making effective multimodal analgesia essential for early mobilization, functional recovery, and reduction of opioid-related…
- Conditions
- Arthroplasty, Replacement, Knee, Nerve Block Assessment, Pain, Postoperative Arthroscopy
- Trial name
- NCT07730216
- Testing
- Adductor Canal Block (ACB) Only
- Where
- Turkey (Türkiye)
- Volunteers
- 623 people
- Sponsor
- Konya City Hospital
Peripheral Nerve Block, Pain Management
Anterior Suprascapular and Axillary vs. Interscalene Block for Analgesia and Diaphragmatic Function in Shoulder Surgery
Shoulder surgeries are among the most frequently performed orthopedic interventions and are often associated with moderate to severe postoperative pain.
- Conditions
- Peripheral Nerve Block, Pain Management, Diaphragm Protective Block, Upper Extremity
- Trial name
- NCT07739303
- Testing
- Interscalene Block, Combination of Axillary and Anterior Suprascapular Blocks
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Ankara Etlik City Hospital
Spinal Cord Injuries, Nerve Injury
Closed-Loop Deep Brain Stimulation for Refractory Chronic Pain
Chronic pain affects 1 in 4 US adults, and many cases are resistant to almost any treatment. Deep brain stimulation (DBS) holds promise as a new option for patients suffering from treatment-resistant chronic pain, but traditional…
- Conditions
- Spinal Cord Injuries, Nerve Injury, Pain, Postoperative, Post Herpetic Neuralgia
- Trial name
- NCT04144972
- Testing
- Medtronic Summit RC+S or Percept RC
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- University of California, San Francisco
Chronic Back Pain, Basivertebral Nerve Ablation
Monopolar Basivertebral Nerve Ablation for Axial Low Back Pain
Determination of efficacy and safety of Monopolar Basivertebral Nerve Ablation for Axial Low Back Pain treatment, including the method optimization.
- Trial name
- NCT07559890
- Testing
- BVN ablation
- Where
- 3 sites in Czechia, Slovakia and 1 more
- Volunteers
- 100 people
- Sponsor
- EPC Education s.r.o.
Superior Cluneal Nerve Entrapment, Chronic Low Back Pain
Ultrasound-Guided Proximal Superior Cluneal Nerve Block for Superior Cluneal Nerve Entrapment
Superior cluneal nerve entrapment (SCNE) is an underrecognized cause of chronic low back pain and gluteal pain that may mimic lumbar spine disorders.
- Trial name
- PRO-SCN (NCT07712406)
- Testing
- Ultrasound-Guided Proximal Superior Cluneal Nerve Block
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Gaziosmanpasa Research and Education Hospital
Lumbar Microdiscectomy, Nerve Block
Comparing Thoracolumbar Interfascial and Quadro Iliac Plane Blocks on Postoperative Opioid Use Following Lumbar Microsurgery
Lumbar microdiscectomy is a commonly used surgical procedure for treating herniated discs. Effective postoperative analgesia is crucial for early mobilization and functional recovery.
- Trial name
- NCT06851533
- Testing
- Standard Analgesia (No Block), Thoracolumbar Interfascial Plane (TLIP) Block, Quadro Iliac Plane Block
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Medipol University
Peripheral Nerve Stimulation, Chronic Neuropathic Pain
Mechanisms of Stimulation for Pain Alleviation
This is a mechanistic randomized controlled trial of patients with chronic neuropathic pain (CNP) in the upper extremities, lower back, pelvis, and lower extremities, randomized to conventional medical management (CMM) or…
- Conditions
- Peripheral Nerve Stimulation, Chronic Neuropathic Pain, Chronic Neuropathic Pain (Below the Shoulders)
- Trial name
- M-SPA (NCT06741579)
- Testing
- Peripheral Nerve Stimulation, Conventional Care Regimen
- Where
- 2 sites in United States
- Volunteers
- 148 people
- Sponsor
- Stanford University
Chemotherapy-induced Peripheral Neuropathy, Nerve Pain
The Effect of Electroacupuncture on Nerve Pain Caused by Chemotherapy (Chemotherapy-Induced Peripheral Neuropathy)
This study is a randomized controlled trial of electroacupuncture (referred to as EA) versus sham acupuncture (referred to as EA) as effective treatments for Chemotherapy-Induced Peripheral Neuropathy (CIPN) pain in cancer…
- Conditions
- Chemotherapy-induced Peripheral Neuropathy, Nerve Pain, Neuropathy, Neuropathy, Painful
- Trial name
- ACT (NCT04917796)
- Testing
- Electroacupuncture
- Where
- 6 sites in United States
- Volunteers
- 255 people
- Sponsor
- Dana-Farber Cancer Institute
Pain Management, Recto Intercostal Nerve Block
Recto-intercostal Fascial Plane Block in Cholecystectomy
This study aims to evaluate whether an ultrasound-guided recto-intercostal fascial plane block performed before surgical incision in patients undergoing laparoscopic cholecystectomy reduces intraoperative opioid and volatile…
- Trial name
- NCT07502833
- Testing
- Procedure: Recto-intercostal fascial plane block
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people
- Sponsor
- Ankara Etlik City Hospital
Pain Management, Capsaicin-Induced Pain
TaVNS for Capsaicin-Induced Pain
Effective pain management remains a major clinical challenge. Transcutaneous auricular vagus nerve stimulation (taVNS) has emerged as a promising, non-invasive neuromodulation technique due to its safety, ease of administration…
- Conditions
- Pain Management, Capsaicin-Induced Pain, Transcranial Magnetic Stimulation Repetitive, Electroencephalography
- Trial name
- NCT07719868
- Testing
- Transcutaneous Auricular Vagus Nerve Stimulation
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Sciatic Leg Pain, Hamstring Muscle Tightness
Acute Effects of Neurodynamics on Strength and Endurance in Athletes
This study explores the acute effects of neurodynamics, an intervention commonly used by physical therapist to improve nerve mobility and decrease pain, on the strength and muscular endurance in the athletic population.
- Conditions
- Sciatic Leg Pain, Hamstring Muscle Tightness, Hamstring Muscle Strain, Hamstring Muscle Strength
- Trial name
- NCT07721220
- Testing
- Sciatic Slider, Sciatic Tensioner, Mechanically loaded neurodynamic sciatic floss
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- High Point University
Eye Pain, Neuropathy, Optic
Alternating and Direct Current Stimulation for Neuropathic Eye Pain
The goal of this clinical intervention is to test if two forms of transcranial current stimulation, transcranial direct current stimulation (tDCS) or transcranial alternating current stimulation (tACS) can alleviate neuropathic…
- Conditions
- Eye Pain, Neuropathy, Optic, Cerebral Injury
- Trial name
- NCT05931250
- Testing
- DC-Stimulator Plus (NeuroConn GmbH, Germany), Sooma direct current stimulator (Sooma, Finland)
- Where
- Sweden
- Volunteers
- 20 people
- Sponsor
- Neil Lagali