Clinical trials: Nephrotic Syndrome
Nephrotic Syndrome
Renal Doppler in Pediatric Patients With Idiopathic Nephrotic Syndrome
The use of the renal resistive index in pediatric patient with idiopathic nephrotic syndrome to detect steroid resistance and to use it as a prognostic instrument of the progression of the disease.
- Trial name
- NCT05912673
- Testing
- renal doppler
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Tanta University
Idiopathic Nephrotic Syndrome
Short-term gluCOCOrticoid in Adult STEROID-sensitive Nephrotic Syndrome: The COCO-ASTEROID Study
This study will compare a short-term course (12 week) glucocorticoid regimen with the Conventional 24-week regimen as originally proposed by KDIGO.
- Trial name
- NCT07151456
- Testing
- Conventional 24-week glucocorticoid regimen, short-term course (12 week) glucocorticoid regimen
- Where
- China
- Volunteers
- 224 people
- Sponsor
- First Affiliated Hospital of Wenzhou Medical University
Nephrotic Syndrome, Hyperlipidemia
Lipid Lowering Agents to Limit Lipid Oxidation and Activation of Clotting System in Nephrotic Syndrome
The purpose of this research study is to learn if using statin in patients with nephrotic syndrome could lower the risk of blood clots.
- Trial name
- OxLDL (NCT01845428)
- Testing
- Pravastatin
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- University of North Carolina, Chapel Hill
Nephrotic Syndrome
Furosemide Alone or Unexpectedly With Solution of Hypertonic Saline in Nephrotic Syndrome
The trial will test the hypothesis that hypertonic saline on top of standard diuretic treatment will help achieve adequate diuresis in patients with nephrotic syndrome.
- Trial name
- FLUSH-NS (NCT03750136)
- Testing
- Hypertonic saline, Furosemide Injection
- Where
- Poland
- Volunteers
- 30 people
- Sponsor
- Medical University of Bialystok
Nephrotic Syndrome, Membranous Nephropathy
Circulating Factors in Nephrotic Syndrome
A prospective observational study to investigate the treatment-associated changes of circulating factors associated with glomerular diseases among patients with de novo nephrotic syndrome admitted to hospital for a kidney biopsy.
- Conditions
- Nephrotic Syndrome, Membranous Nephropathy, Minimal Change Disease, Primary Focal Segmental Glomerulosclerosis
- Trial name
- NCT06315504
- Testing
- Observation
- Volunteers
- 104 people
- Sponsor
- Iain Bressendorff
Nephrotic Syndrome
Fluid Balance, Hormones and Urine Proteomics in Nephrotic Syndrome in Childhood
The purpose of this study is to describe the hormones controlling fluid balance in pediatric patients with nephrotic syndrome. Further more, an analysis of the urinary and plasma proteins will be done using proteomics.
- Trial name
- NCT00690586
- Where
- Denmark
- Volunteers
- 21 people
- Sponsor
- Aarhus University Hospital
Nephrotic Syndrome
Long Term Tapering or Standard Steroids for Nephrotic Syndrome
Parallel group double blind randomised in patients with first episode corticosteroid sensitive nephrotic syndrome comparing time to relapse and adverse effects associated with a longer tapering steroid regimen with standard regime
- Trial name
- NCT00308321
- Testing
- long term tapering of prednisolone, standard prednisolone treatment
- Where
- United Kingdom
- Volunteers
- 50 people
- Sponsor
- Institute of Child Health
Membranous Nephropathy, Nephrotic Syndrome
Belimumab With Rituximab for Primary Membranous Nephropathy
The primary objective of this study is to evaluate the effectiveness of belimumab and intravenous rituximab co-administration at inducing a complete or partial remission (CR or PR) compared to rituximab alone in participants with…
- Trial name
- REBOOT (NCT03949855)
- Testing
- Belimumab, Rituximab
- Where
- 20 sites in United States
- Volunteers
- 58 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Nephrotic Syndrome, Rituximab
Clinical Follow-up Study of Rituximab in the Treatment of Nephrotic Syndrome in Children
This was a retrospective study. Children who were diagnosed with refractory nephrotic syndrome and treated with rituximab (RTX) and followed up for ≥1 year in the Department of Pediatrics, the First Affiliated Hospital of Xiamen…
- Conditions
- Nephrotic Syndrome, Rituximab, Children, Efficacy
- Trial name
- NCT06530004
- Testing
- Rituximab
- Where
- China
- Volunteers
- 50 people
- Sponsor
- The First Affiliated Hospital of Xiamen University
Minimal Change Disease
Therapeutic Effect of Tacrolimus in Combination With Low Dose Corticosteroid in Adult Patient With Minimal Change Nephritic Syndrome
The hypothesis of this study is that tacrolimus reduces the proteinuria in adult patient with minimal change nephritic syndrome.
- Trial name
- MCNS (NCT01084980)
- Testing
- Tacrolimus
- Where
- South Korea
- Volunteers
- 20 people
- Sponsor
- Seoul National University Hospital