Clinical trials: Neonatology
Pre-Term
Modelling Weight Reference Centiles for Preterm Infants
The aim of this study is to model longitudinal data at NICU of Assuit University Children Hospital to create predictive growth charts for weight in preterm infants from birth till discharge, that take into account the differing…
- Trial name
- NCT04333121
- Testing
- weight
- Volunteers
- 100 people
- Sponsor
- Assiut University
Newborns, Neonatology
Interest of Peripheral Venous Catheter Insertion Using a Micro-guide in Neonatology
Peripheral venous catheterization represents the preferential option for term or preterm infant care in order to start drug treatment or hydration, or perform anesthesia.
- Conditions
- Newborns, Neonatology, Intensive Care
- Trial name
- EASYCATH (NCT04984967)
- Testing
- Insertion of peripheral venous catheter with micro-guide, Classic insertion of peripheral venous catheter, without micro-guide
- Where
- France
- Volunteers
- 116 people
- Sponsor
- University Hospital, Montpellier
Simulation-based Training on Residents
Efficacy of Simulation-based Neonatal Echocardiography Training (SimuEchoNeo)
Echocardiographic examination plays a critical role in neonatology, but its bedside training faces challenges due to limited patient access.
- Trial name
- SimuEchoNeo (NCT06442683)
- Testing
- TTE simulation-based medical training
- Where
- 3 sites in France
- Volunteers
- 52 people
- Sponsor
- University Hospital, Caen
Respiratory Distress Syndrome, Newborn
LISA vs Endotracheal Surfactant in Preterm Neonates: A Lung Ultrasound Distribution Study
This prospective, non-randomized, unblinded pilot study evaluates and compares the intrapulmonary distribution of exogenous surfactant in preterm neonates when administered via Less Invasive Surfactant Administration (LISA)…
- Trial name
- LISA-Ven-LUS (NCT07514481)
- Testing
- surfactant administration by ETT, surfactant administration by thin catheter
- Where
- Qatar
- Volunteers
- 22 people
- Sponsor
- Hamad General Hospital
Preterm Birth
What is the Future of Vulnerable New-borns
The aim of this data base is to know exactly the future of a "vulnerable newborns" cared in Pontoise Hospital (In the neonatology service) and compare the information with the national data of preterm birth.
- Trial name
- DNNV (NCT04021654)
- Testing
- Data collection
- Where
- France
- Volunteers
- 257 people
- Sponsor
- Hôpital NOVO
Neonatology
Optimization and Clinical Study of Early Prediction Model for Neonatal Acute Respiratory Distress Syndrome
The goal of this observational study is to learn about neonatal acute respiratory distress syndrome in describe participant population.
- Trial name
- NCT05647850
- Testing
- No intervention
- Where
- 2 sites in China
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- University-Town Hospital of Chongqing Medical University
Pain Score
Prevention of Pain Caused by the Oro-gastric Tube Laying in Neonatology
Subject of research : Evaluation of a technique of care to reduce the pain caused by the laying of the gastric tube in the newborn
- Trial name
- DOLATSONG (NCT03142230)
- Testing
- the laying of the gastric tube and a group using the holed baby bottle nipple, the feeding tube ideally positioned at the center of the intersection pharyngeal, the laying of the gastric tube and a group with simple non-nutritive suction, the feeding tube passing next to the newborn's personal pacifier
- Where
- 3 sites in France
- Volunteers
- 71 people
- Sponsor
- Centre Hospitalier Sud Francilien
Necrotizing Enterocolitis
Identification of Clostridium Butyricum and Clostridium Neonatal in the Digestive Microbiota of Premature Infants Before 34 Weeks and Developing or Not Ulcerative Necrotizing Enterocolitis (NEC) During Hospitalization
The study investigators hypothesize that Clostridium butyricum and Clostridium neonatal will be more frequently found in the stool of preterm infants with ulcerative necrotizing enterocolitis compared to healthy matched control…
- Trial name
- ECUN-2 (NCT04584320)
- Testing
- Stool sample
- Where
- France
- Volunteers
- 40 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Prematurity, Eye Fundus
Benefit of Singing in the Care of Premature Children Undergoing Screening for Retinopathy of Prematurity in the Neonatology and Neonatal Resuscitation Unit of the Dijon University Hospital
As part of the regular procedure for premature births, premature infants undergo several screening examinations, including an examination of the fundus.
- Trial name
- Voix Chantée (NCT03830580)
- Testing
- Positive stimulation (singing)
- Where
- France
- Volunteers
- 40 people
- Sponsor
- Centre Hospitalier Universitaire Dijon
Premature Lungs
Clinical Trial for the Evaluation of Customized 3D Printed NIV Nasal Masks in Premature Infants
Clinical trial with crossed groups, open, masked for the evaluation of the main outcome. Inclusion of all premature infants with a birth weight less than 1500 g requiring Non-invasive Ventilation (NIV).
- Trial name
- M3DPREMAT (NCT06224816)
- Testing
- Custom 3D mask (3DM) application in neonate, Traditional mask (TM) application in neonate
- Where
- Spain
- Volunteers
- 60 people
- Sponsor
- Hospital Universitario 12 de Octubre
Neonatology
A Stylet Use May be Beneficial for Elective and Rescue Intubation of Prematurely Born Infants
Contrary to recent findings suggesting that stylets offer no advantage in general infant intubations, this study focuses on their potential benefits for premature infants undergoing elective or rescue intubation in the delivery…
- Trial name
- NCT06316765
- Testing
- Intubation with stylet
- Volunteers
- 70 people
- Sponsor
- Charles University, Czech Republic
Neonatal Critical Care
Palliative Care in Maternity and Neonatology
Palliative care is now an accepted principle in most maternity and neonatology wards, however not much is known about its psychological and social consequences on families.
- Trial name
- VESPAN (NCT04619901)
- Testing
- Semi-structured interviews, Questionnaire, following Scales
- Where
- 4 sites in France
- Volunteers
- 1 people
- Sponsor
- University Hospital, Lille
Nephrocalcinosis, Preterm Infant
The Incidence and the Risk Factors of Nephrocalcinosis in Very Preterm Infants
The study aims to assess the incidence and the risk factors of nephrocalcinosis in very preterm infants using patient data collected during hospitalisation at the Neonatology Centre.
- Trial name
- NCT04382976
- Where
- Lithuania
- Volunteers
- 171 people
- Sponsor
- Vilnius University
The Focus of the Study is to Provide a Guideline on Osteopathic Approach in Treating Hospitalized Newborns.
Osteopathic Approach Into Neonatology Ward: the NE-O Model
Background Several studies have shown the effect of osteopathic manipulative treatment on neonatal care in reducing length of stay, gastrointestinal problems, clubfoot complications and improving cranial asymmetry of infants…
- Trial name
- NCT01902563
- Testing
- Osteopathic Manipulative Treatment
- Sponsor
- European Institute for Evidence Based Osteopathic Medicine
Neonatology
The Impact of Non-Routine Events on Neonatal Safety
The study objective is to decrease neonatal mortality and morbidity by elucidating the etiology of system failures during perioperative care.
- Trial name
- NCT02756195
- Where
- United States
- Volunteers
- 395 people
- Sponsor
- Vanderbilt University
Neonatal Intensive Care
Neonatal Mask Seal; a Two-handed Versus One-handed Approach: The NeoSeal Study
When babies can't breathe effectively, we can use a facemask to give them breaths and oxygen. The mask can be held with one or two hands, depending on the preference of the doctor.
- Trial name
- NeoSeal (NCT06740344)
- Testing
- Two-handed facemask hold, Control: One-handed facemask hold
- Where
- Ireland
- Volunteers
- 110 people
- Sponsor
- University College Dublin
Prematurity, Parenting
Study of the Quality of Sleep of Parents of Premature Children Compared to Parents of Full-term Children
This study evaluate the incidence of sleep disorders in parents of premature children hospitalized in unit care of neonatalogy or intensive unit care of neonatalogy, compared to parents of full-term child in maternity.
- Conditions
- Prematurity, Parenting, Sleep Deprivation
- Trial name
- SLEEP-PP (NCT03693651)
- Where
- France
- Volunteers
- 306 people, healthy volunteers welcome
- Sponsor
- University Hospital, Brest
Adverse Reaction to Drug, Neonatal Disorder
Exploratory Propofol Dose Finding Study In Neonates
The aim of the study is to explore the optimal propofol dose in neonates receiving a single intravenous propofol bolus for endotracheal intubation during (semi-)elective INSURE (intubation-surfactant-extubation) procedure…
- Trial name
- NEOPROP (NCT01621373)
- Testing
- propofol administration
- Where
- Belgium
- Volunteers
- 50 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Premature Birth
Decision Making in Neonatology : a Qualitative Study
This study aimed to describe and understand the decision making process in neonatology in situations of limiting of withdraw life sustaining treatments, by conducting interviews with physicians from one neonatology unit.
- Trial name
- PRODA (NCT03323970)
- Testing
- semi-structured interviews
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Besancon
EEG, Neonatology
An Observational Study of the NeuroBell EEG Monitor
An observational clinical investigation of the NeuroBell EEG Monitor (a portable and wireless EEG monitor).
- Conditions
- EEG, Neonatology, Seizure, Neurology
- Trial name
- NCT07508670
- Testing
- NeuroBell EEG Monitor
- Where
- Ireland
- Volunteers
- 17 people
- Sponsor
- University College Cork